Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 17546938

GI number: 17546938

Start: 2406380

End: 2407423

Strand: Direct

Name: gcp [H]

Synonym: RSc2219

Alternate gene names: 17546938

Gene position: 2406380-2407423 (Clockwise)

Preceding gene: 17546931

Following gene: 17546943

Centisome position: 64.75

GC content: 70.5

Gene sequence:

>1044_bases
ATGCTGGTCCTCGGCATCGAATCCTCCTGCGACGAAACCGGCGTCGCCCTGTACGACACCGACGCCGGCCTGCGCGCGCA
CGCGCTCTACTCGCAGATCGCCATGCACCGCGACTACGGCGGCGTGGTGCCGGAGCTGGCCTCGCGCGACCACATCCGCC
GCGTGATCCCGCTGCTGGAGGACGTGCTGGCCGAGGCCGGCGTCGGCCGCGCGGACATCGACGCCATCGCCTATACGAAA
GGGCCCGGACTGGCCGGCGCGCTGCTGGTGGGAGCCTCGGTCGCCAATGCGCTGGGCTTTGCGCTGGGCAAGCCGCTGGT
GGGCGTGCATCACCTGGAAGGGCATCTGCTCTCGCCGCTGCTGGAGGCGGACCGGCCCGCGTTTCCGTTCCTGGCGCTGC
TGGTGTCGGGCGGGCACACGCAGTTGATGCGCGTCGATGCGGTCGGCCAGTACACGCTGCTGGGCGAAACCCTCGACGAT
GCCGCCGGCGAGGCCTTCGACAAGACCGCCAAGCTGCTCGGCCTCGGGTATCCCGGCGGCCCGGCCGTCTCGCGGCTGGC
CGAGTTCGGCAACCCGGGCGCGTTCGAGCTGCCCCGGCCGATGCTGCATTCGGGCAATTTCGATTTCTCGTTCGCCGGTC
TGAAGACCGCCGTGCTGACGCAGGTGCGCAAACTCAATCTCGACGGCGGCGAGGCATGCGAACAGCCGCGCGCCGACTTG
GCCCGCGCCTTCGTCGATGCCATCGTCGACGTGCTCGTCGCCAAGACGCTGCGCGCCGCGCGCGAGCACGGCCTCAAGCG
CATCGTGGTGGCGGGCGGCGTGGGCGCCAACCGCCAGTTGCGCGAGCGCCTGAATGCCGAAGGCGGCAAGCGTGGCCTGC
GCGTCTACTACCCCGACCTGCAGTTCTGCACCGACAACGGCGCCATGATCGCTTTCGCCGGCGCGATGCGGCTGCAGGCC
GACCCCGGCCAGGTCCAGTCAGGCTACGGCTACGGCGTCACGCCGCGCTGGGACCTGGAAGACATCCGCATCCGGCAGGC
ATGA

Upstream 100 bases:

>100_bases
GCGCCGCCCCTTGGTTGCCTGTCTGTACGAAAACCGCGCATTTTAACTTGTGCTATCTTCGGCGGCCTTCCCATTGCATT
TCCTCACGCCTTCACGCGCC

Downstream 100 bases:

>100_bases
AAAAAGCCGCTCGATGGGGCGGCTTCTTCCGGGGGTCGGCGTCGATCAGCCGGCGCGGCGCTTGTCGCGCTCGATCAAGG
CATAGGCGCTGTGGTTGTGG

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLVLGIESSCDETGVALYDTDAGLRAHALYSQIAMHRDYGGVVPELASRDHIRRVIPLLEDVLAEAGVGRADIDAIAYTK
GPGLAGALLVGASVANALGFALGKPLVGVHHLEGHLLSPLLEADRPAFPFLALLVSGGHTQLMRVDAVGQYTLLGETLDD
AAGEAFDKTAKLLGLGYPGGPAVSRLAEFGNPGAFELPRPMLHSGNFDFSFAGLKTAVLTQVRKLNLDGGEACEQPRADL
ARAFVDAIVDVLVAKTLRAAREHGLKRIVVAGGVGANRQLRERLNAEGGKRGLRVYYPDLQFCTDNGAMIAFAGAMRLQA
DPGQVQSGYGYGVTPRWDLEDIRIRQA

Sequences:

>Translated_347_residues
MLVLGIESSCDETGVALYDTDAGLRAHALYSQIAMHRDYGGVVPELASRDHIRRVIPLLEDVLAEAGVGRADIDAIAYTK
GPGLAGALLVGASVANALGFALGKPLVGVHHLEGHLLSPLLEADRPAFPFLALLVSGGHTQLMRVDAVGQYTLLGETLDD
AAGEAFDKTAKLLGLGYPGGPAVSRLAEFGNPGAFELPRPMLHSGNFDFSFAGLKTAVLTQVRKLNLDGGEACEQPRADL
ARAFVDAIVDVLVAKTLRAAREHGLKRIVVAGGVGANRQLRERLNAEGGKRGLRVYYPDLQFCTDNGAMIAFAGAMRLQA
DPGQVQSGYGYGVTPRWDLEDIRIRQA
>Mature_347_residues
MLVLGIESSCDETGVALYDTDAGLRAHALYSQIAMHRDYGGVVPELASRDHIRRVIPLLEDVLAEAGVGRADIDAIAYTK
GPGLAGALLVGASVANALGFALGKPLVGVHHLEGHLLSPLLEADRPAFPFLALLVSGGHTQLMRVDAVGQYTLLGETLDD
AAGEAFDKTAKLLGLGYPGGPAVSRLAEFGNPGAFELPRPMLHSGNFDFSFAGLKTAVLTQVRKLNLDGGEACEQPRADL
ARAFVDAIVDVLVAKTLRAAREHGLKRIVVAGGVGANRQLRERLNAEGGKRGLRVYYPDLQFCTDNGAMIAFAGAMRLQA
DPGQVQSGYGYGVTPRWDLEDIRIRQA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=356, Percent_Identity=35.3932584269663, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI8923380, Length=346, Percent_Identity=32.0809248554913, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=57.0175438596491, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788109, Length=112, Percent_Identity=29.4642857142857, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17557464, Length=334, Percent_Identity=32.6347305389222, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=31.8042813455657, Blast_Score=133, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320099, Length=351, Percent_Identity=33.3333333333333, Blast_Score=170, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322891, Length=352, Percent_Identity=28.6931818181818, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI20129063, Length=352, Percent_Identity=34.9431818181818, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21357207, Length=323, Percent_Identity=32.1981424148607, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36801; Mature: 36801

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIESSCDETGVALYDTDAGLRAHALYSQIAMHRDYGGVVPELASRDHIRRVIPLLE
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DVLAEAGVGRADIDAIAYTKGPGLAGALLVGASVANALGFALGKPLVGVHHLEGHLLSPL
HHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LEADRPAFPFLALLVSGGHTQLMRVDAVGQYTLLGETLDDAAGEAFDKTAKLLGLGYPGG
HHCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
PAVSRLAEFGNPGAFELPRPMLHSGNFDFSFAGLKTAVLTQVRKLNLDGGEACEQPRADL
HHHHHHHHCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHCCHHHHH
ARAFVDAIVDVLVAKTLRAAREHGLKRIVVAGGVGANRQLRERLNAEGGKRGLRVYYPDL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCEEEECCE
QFCTDNGAMIAFAGAMRLQADPGQVQSGYGYGVTPRWDLEDIRIRQA
EEECCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCCHHHCEEECC
>Mature Secondary Structure
MLVLGIESSCDETGVALYDTDAGLRAHALYSQIAMHRDYGGVVPELASRDHIRRVIPLLE
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DVLAEAGVGRADIDAIAYTKGPGLAGALLVGASVANALGFALGKPLVGVHHLEGHLLSPL
HHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LEADRPAFPFLALLVSGGHTQLMRVDAVGQYTLLGETLDDAAGEAFDKTAKLLGLGYPGG
HHCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
PAVSRLAEFGNPGAFELPRPMLHSGNFDFSFAGLKTAVLTQVRKLNLDGGEACEQPRADL
HHHHHHHHCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHCCHHHHH
ARAFVDAIVDVLVAKTLRAAREHGLKRIVVAGGVGANRQLRERLNAEGGKRGLRVYYPDL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCEEEECCE
QFCTDNGAMIAFAGAMRLQADPGQVQSGYGYGVTPRWDLEDIRIRQA
EEECCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCCHHHCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA