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The map label for this gene is yggW [H]

Identifier: 17546880

GI number: 17546880

Start: 2343596

End: 2344870

Strand: Direct

Name: yggW [H]

Synonym: RSc2161

Alternate gene names: 17546880

Gene position: 2343596-2344870 (Clockwise)

Preceding gene: 17546879

Following gene: 17546882

Centisome position: 63.06

GC content: 68.78

Gene sequence:

>1275_bases
ATGATTCCGATCCACCCCGTGGGCGGGAGCCAGACGCCCGCTTCTTCCACCGCCGCAGCCGGGACCGGCGATGCCGTCAC
GTCGGTCTTCCTGCAGCCGGGCAGGATCAGCCTGCCGGCCTCGCCGCCGCTGTCGCTCTATGTGCATGTGCCGTGGTGCG
TGCGCAAATGCCCCTATTGCGATTTCAACTCGCATGCGGAGCCGGAGGCGGGCATCCCGGAAGACCGCTTCCTCGCGGCC
ATCCGGCAGGACCTGGAGGCCGCGCTGCCGATGGTGTGGGGCCGACGCGTGCATACGATCTTCATCGGCGGCGGCACGCC
GAGCCTGCTGTCGGCGCGGGGGCTGGATACGCTGCTGTCGGACATCCGCATGCTGCTGCCGGTCGATGCGGATGCCGAGA
TCACCATGGAGGCCAATCCCGGCACCTTCGAGGCCGAGCGCTTCCGCAGCTATCGGGCCAGCGGCGTGAACCGGCTGTCG
ATCGGCATCCAGAGCTTCAACGACACGCACCTGCAGGCGCTGGGCCGCATCCACAGCGCCGCCGAGGCACGGGCGGCCAT
CGACATCGCCCGCGCGCACTTCGACAACATCAACCTCGACCTGATGTTCGCCCTGCCCGGCCAGACCCTGGCCGAATGCG
AGGCCGATGTGGAAGCCGCGCTGTCGTTCGGCACCAGCCACGTCTCGCTGTACCACCTGACGCTGGAGCCCAACACCTAC
TTTGCCAAGCACCCGCCCGCGCTGCCGGACGACGACACCGCGTTCGCCATGCAGGACTGGATCCACGCACGGCTGGCCGC
GGCCGGCTACGAGCACTACGAGGTGTCGGCCTACGCCAGGCCGGGCAAGCGCTGCAAGCACAACCTGAACTACTGGCAGT
TCGGCGATTACCTCGGCATCGGGCCGGGCGCGCACGGCAAGCTGAGCTTTCCGCACCGGGTGATCCGGGACATGCGCCAC
AAGCACCCCGAGACCTACCTGCGCCAGGCGGAAACGGCCGGCGGCGCGACGGTGGTGCAGGAGCAGCGCGAAGTCGACGC
GGCCGACCTGCCGTTCGAGTTCATGCTCAACGCGCTGCGGCTGACCGACGGCTTCCCCGTCACGCTGTTCCAGGAGCGCA
CCGGCCTGCCGCTGCGCGGCATCGAGCGCGAACTCGATGCCGCCGAGCGGCGCGGCCTGCTCGTGCACGACCACGCAACG
ATCCGGCCGACCGAACTGGGCCAGCGCTTTCTCAACGATCTGCAGGCGCTGTTCCTCGCCGACGACGAAAACTGA

Upstream 100 bases:

>100_bases
CGAGCTGTCCAAGGCCGAGAAGAATGCCGTCAGCCACCGCGCGCAAGCGCTCGCGCAGCTGGTCGAGCGGCTGCGCCTGT
TCGAGAACGCCTGACGCTTC

Downstream 100 bases:

>100_bases
CAATCCCGTCGGCCGGCGGACTGTGCTGCCGCGCCGGCAGCCGTTACAATGGCGGCCTCGCGCGCCATGTGCGCGCATGC
CGTCTCCGGAAGCGTGGCCG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MIPIHPVGGSQTPASSTAAAGTGDAVTSVFLQPGRISLPASPPLSLYVHVPWCVRKCPYCDFNSHAEPEAGIPEDRFLAA
IRQDLEAALPMVWGRRVHTIFIGGGTPSLLSARGLDTLLSDIRMLLPVDADAEITMEANPGTFEAERFRSYRASGVNRLS
IGIQSFNDTHLQALGRIHSAAEARAAIDIARAHFDNINLDLMFALPGQTLAECEADVEAALSFGTSHVSLYHLTLEPNTY
FAKHPPALPDDDTAFAMQDWIHARLAAAGYEHYEVSAYARPGKRCKHNLNYWQFGDYLGIGPGAHGKLSFPHRVIRDMRH
KHPETYLRQAETAGGATVVQEQREVDAADLPFEFMLNALRLTDGFPVTLFQERTGLPLRGIERELDAAERRGLLVHDHAT
IRPTELGQRFLNDLQALFLADDEN

Sequences:

>Translated_424_residues
MIPIHPVGGSQTPASSTAAAGTGDAVTSVFLQPGRISLPASPPLSLYVHVPWCVRKCPYCDFNSHAEPEAGIPEDRFLAA
IRQDLEAALPMVWGRRVHTIFIGGGTPSLLSARGLDTLLSDIRMLLPVDADAEITMEANPGTFEAERFRSYRASGVNRLS
IGIQSFNDTHLQALGRIHSAAEARAAIDIARAHFDNINLDLMFALPGQTLAECEADVEAALSFGTSHVSLYHLTLEPNTY
FAKHPPALPDDDTAFAMQDWIHARLAAAGYEHYEVSAYARPGKRCKHNLNYWQFGDYLGIGPGAHGKLSFPHRVIRDMRH
KHPETYLRQAETAGGATVVQEQREVDAADLPFEFMLNALRLTDGFPVTLFQERTGLPLRGIERELDAAERRGLLVHDHAT
IRPTELGQRFLNDLQALFLADDEN
>Mature_424_residues
MIPIHPVGGSQTPASSTAAAGTGDAVTSVFLQPGRISLPASPPLSLYVHVPWCVRKCPYCDFNSHAEPEAGIPEDRFLAA
IRQDLEAALPMVWGRRVHTIFIGGGTPSLLSARGLDTLLSDIRMLLPVDADAEITMEANPGTFEAERFRSYRASGVNRLS
IGIQSFNDTHLQALGRIHSAAEARAAIDIARAHFDNINLDLMFALPGQTLAECEADVEAALSFGTSHVSLYHLTLEPNTY
FAKHPPALPDDDTAFAMQDWIHARLAAAGYEHYEVSAYARPGKRCKHNLNYWQFGDYLGIGPGAHGKLSFPHRVIRDMRH
KHPETYLRQAETAGGATVVQEQREVDAADLPFEFMLNALRLTDGFPVTLFQERTGLPLRGIERELDAAERRGLLVHDHAT
IRPTELGQRFLNDLQALFLADDEN

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=279, Percent_Identity=40.1433691756272, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=49.2146596858639, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI87082341, Length=285, Percent_Identity=27.719298245614, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 46672; Mature: 46672

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPIHPVGGSQTPASSTAAAGTGDAVTSVFLQPGRISLPASPPLSLYVHVPWCVRKCPYC
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHEECCCEEECCCCCCCEEEEECCHHHHHCCCC
DFNSHAEPEAGIPEDRFLAAIRQDLEAALPMVWGRRVHTIFIGGGTPSLLSARGLDTLLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCHHHHHH
DIRMLLPVDADAEITMEANPGTFEAERFRSYRASGVNRLSIGIQSFNDTHLQALGRIHSA
HHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHH
AEARAAIDIARAHFDNINLDLMFALPGQTLAECEADVEAALSFGTSHVSLYHLTLEPNTY
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCE
FAKHPPALPDDDTAFAMQDWIHARLAAAGYEHYEVSAYARPGKRCKHNLNYWQFGDYLGI
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCCEECCCCCCC
GPGAHGKLSFPHRVIRDMRHKHPETYLRQAETAGGATVVQEQREVDAADLPFEFMLNALR
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHH
LTDGFPVTLFQERTGLPLRGIERELDAAERRGLLVHDHATIRPTELGQRFLNDLQALFLA
HCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHEEEEE
DDEN
CCCC
>Mature Secondary Structure
MIPIHPVGGSQTPASSTAAAGTGDAVTSVFLQPGRISLPASPPLSLYVHVPWCVRKCPYC
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHEECCCEEECCCCCCCEEEEECCHHHHHCCCC
DFNSHAEPEAGIPEDRFLAAIRQDLEAALPMVWGRRVHTIFIGGGTPSLLSARGLDTLLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCHHHHHH
DIRMLLPVDADAEITMEANPGTFEAERFRSYRASGVNRLSIGIQSFNDTHLQALGRIHSA
HHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHH
AEARAAIDIARAHFDNINLDLMFALPGQTLAECEADVEAALSFGTSHVSLYHLTLEPNTY
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCE
FAKHPPALPDDDTAFAMQDWIHARLAAAGYEHYEVSAYARPGKRCKHNLNYWQFGDYLGI
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCCEECCCCCCC
GPGAHGKLSFPHRVIRDMRHKHPETYLRQAETAGGATVVQEQREVDAADLPFEFMLNALR
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHH
LTDGFPVTLFQERTGLPLRGIERELDAAERRGLLVHDHATIRPTELGQRFLNDLQALFLA
HCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHEEEEE
DDEN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]