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The map label for this gene is yaaU [H]

Identifier: 17546831

GI number: 17546831

Start: 2287104

End: 2288432

Strand: Reverse

Name: yaaU [H]

Synonym: RSc2112

Alternate gene names: 17546831

Gene position: 2288432-2287104 (Counterclockwise)

Preceding gene: 17546832

Following gene: 17546830

Centisome position: 61.58

GC content: 63.96

Gene sequence:

>1329_bases
GTGGCAAACAACGTTTCTATCGAAGACGTTCCTTTGAATGGCTTCCATCAACTGCTCAGCATTCGATCCGGCGGCGGCTG
GGTCCTGGACGGCTACGTACTGAGCATCATCGGCGTGGCCATGGTGCAGTTGTCGGCGGCGCTGCATTTGAGCGGCTTCT
GGCAAGGCATGGTTGCGGCCTCGGCCTTGATCGGGATTTTCTGCGGAGGCTTCCTGGGCGGGCTGCTGACCGGATGCCTG
GGCCGCCAGAAGCTGTACTTCTTCGGTCCGACGATTTTCGTGGTGTGCTCGCTGGCGCAGTTCTGGGCGGATTCCGGCGC
GGCGCTGTTCTTCTTCCGATTCCTGATCGGGGTCGGTGTCGGGTTCGAATACCCGGTTGCGGGTTCCTTGCTGGTGGAGT
TCATGCCCAGGAAAGATCGAGGCCCGCGCTTGGCGATGCTGACCATCCTGTGGTTCGCCGGTGCGGCGCTGGCTTACATG
GTGGGCAACGCGATCCTGGATACCGGGCGTGCCGACGCATGGAGACTGGTCCTCGCAAGCCCGGCCGTCATCGGCGCACT
GCTGTTGCTGGTGCGCATCGGGACGCCAGAGTCGCCTCGCTGGCTGTTGAGCAAAGGGCGGGCAGCGGAGGCCGAGCGCG
TCATCCAGCAGGTCTATGGCCCCCAGTTTTCGCTCGAGAATCTTCCCGAACAACGGCCGGAGAAGAAGGTGTCGCTCCTG
AGCCTGCTGCACTCCGGGTACGGCAAGCGCATGCTGTTCGTGTCGGTCTTCTGGAGCTGCTCGGTGATTCCCGTGTTTGC
CGTGTACGCATTCGCGCCCACGGTACTGCAGGCGTTGCATCTGAAAGGGGCCTGGGCGTCGTTCGGCTCCGTGGCCATCA
CGCTGCTGTTCGTGGTCGGCTGTTTCGTCGCCACGCGGCTGATCAATACCGTCGGCCGCCGCAGCATGCTCATCCATAGC
TTCCTGTGGTCGGGGCTGGCGCTGCTGGGATTGGGCCTCTTCTGCGACGGCTCGGAAATGCTGGTGCTCGTGCTGTTCGG
TGCCTATGCCGTGTTTATCGGCGGTGCGCAGGTATTGCAGCTGGTCTATCCGAATGAGCTGTTTCCCACCGAAATCCGGT
CGGCCGCGGTGGGCATGGGGGCCTCGCTGTCGCGCATCGGCGCAGCCATTGGAACGTGGGCGGTCCCCGTCGCGCTGCAG
GGCATTGGTGTCGGCAACACGATGTTCGCGGCGGCCGGGGTGACGCTGTTCGGCCTGCTGGTGTCACTGGCCATCGCCCC
GGAAACGCGCGCGCTCAGCTTGCAGGAGGCGGCTTCGCTCAGTCGCTAG

Upstream 100 bases:

>100_bases
CATCAATAGGTATTGCCGAATGCCATAAACCGATTTCATTGATTAGACCCGGATTCATCATTCCATTTCACATCATCCGG
GCATTTGCAGGAGACAAAAG

Downstream 100 bases:

>100_bases
TTTCCCCGTGTCGCCGGTGGCGCGACCGGCGACGCAGTCTCTTCCTTGAAAACGACGCTTCCGCTTGAACGGAGAAAAGC
AATCATGAAATTCGAAGGCA

Product: metabolite transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MANNVSIEDVPLNGFHQLLSIRSGGGWVLDGYVLSIIGVAMVQLSAALHLSGFWQGMVAASALIGIFCGGFLGGLLTGCL
GRQKLYFFGPTIFVVCSLAQFWADSGAALFFFRFLIGVGVGFEYPVAGSLLVEFMPRKDRGPRLAMLTILWFAGAALAYM
VGNAILDTGRADAWRLVLASPAVIGALLLLVRIGTPESPRWLLSKGRAAEAERVIQQVYGPQFSLENLPEQRPEKKVSLL
SLLHSGYGKRMLFVSVFWSCSVIPVFAVYAFAPTVLQALHLKGAWASFGSVAITLLFVVGCFVATRLINTVGRRSMLIHS
FLWSGLALLGLGLFCDGSEMLVLVLFGAYAVFIGGAQVLQLVYPNELFPTEIRSAAVGMGASLSRIGAAIGTWAVPVALQ
GIGVGNTMFAAAGVTLFGLLVSLAIAPETRALSLQEAASLSR

Sequences:

>Translated_442_residues
MANNVSIEDVPLNGFHQLLSIRSGGGWVLDGYVLSIIGVAMVQLSAALHLSGFWQGMVAASALIGIFCGGFLGGLLTGCL
GRQKLYFFGPTIFVVCSLAQFWADSGAALFFFRFLIGVGVGFEYPVAGSLLVEFMPRKDRGPRLAMLTILWFAGAALAYM
VGNAILDTGRADAWRLVLASPAVIGALLLLVRIGTPESPRWLLSKGRAAEAERVIQQVYGPQFSLENLPEQRPEKKVSLL
SLLHSGYGKRMLFVSVFWSCSVIPVFAVYAFAPTVLQALHLKGAWASFGSVAITLLFVVGCFVATRLINTVGRRSMLIHS
FLWSGLALLGLGLFCDGSEMLVLVLFGAYAVFIGGAQVLQLVYPNELFPTEIRSAAVGMGASLSRIGAAIGTWAVPVALQ
GIGVGNTMFAAAGVTLFGLLVSLAIAPETRALSLQEAASLSR
>Mature_441_residues
ANNVSIEDVPLNGFHQLLSIRSGGGWVLDGYVLSIIGVAMVQLSAALHLSGFWQGMVAASALIGIFCGGFLGGLLTGCLG
RQKLYFFGPTIFVVCSLAQFWADSGAALFFFRFLIGVGVGFEYPVAGSLLVEFMPRKDRGPRLAMLTILWFAGAALAYMV
GNAILDTGRADAWRLVLASPAVIGALLLLVRIGTPESPRWLLSKGRAAEAERVIQQVYGPQFSLENLPEQRPEKKVSLLS
LLHSGYGKRMLFVSVFWSCSVIPVFAVYAFAPTVLQALHLKGAWASFGSVAITLLFVVGCFVATRLINTVGRRSMLIHSF
LWSGLALLGLGLFCDGSEMLVLVLFGAYAVFIGGAQVLQLVYPNELFPTEIRSAAVGMGASLSRIGAAIGTWAVPVALQG
IGVGNTMFAAAGVTLFGLLVSLAIAPETRALSLQEAASLSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI203098995, Length=215, Percent_Identity=26.9767441860465, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI24497490, Length=344, Percent_Identity=27.0348837209302, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI7662270, Length=216, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI216548223, Length=197, Percent_Identity=30.9644670050761, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21553331, Length=311, Percent_Identity=24.1157556270096, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI213021148, Length=473, Percent_Identity=22.6215644820296, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI262399383, Length=182, Percent_Identity=29.1208791208791, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786229, Length=442, Percent_Identity=39.3665158371041, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI87082159, Length=436, Percent_Identity=37.1559633027523, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1789312, Length=425, Percent_Identity=25.4117647058824, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790463, Length=420, Percent_Identity=22.1428571428571, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789207, Length=224, Percent_Identity=29.0178571428571, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788074, Length=386, Percent_Identity=23.8341968911917, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788068, Length=450, Percent_Identity=25.5555555555556, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=463, Percent_Identity=20.7343412526998, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71986689, Length=350, Percent_Identity=24.2857142857143, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193202825, Length=350, Percent_Identity=24.2857142857143, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193206721, Length=430, Percent_Identity=23.7209302325581, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=509, Percent_Identity=23.1827111984283, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24663515, Length=401, Percent_Identity=23.9401496259352, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24663519, Length=401, Percent_Identity=23.9401496259352, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24663511, Length=401, Percent_Identity=23.9401496259352, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24649622, Length=365, Percent_Identity=24.9315068493151, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19922616, Length=402, Percent_Identity=23.3830845771144, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24668440, Length=402, Percent_Identity=23.6318407960199, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 46974; Mature: 46843

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANNVSIEDVPLNGFHQLLSIRSGGGWVLDGYVLSIIGVAMVQLSAALHLSGFWQGMVAA
CCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALIGIFCGGFLGGLLTGCLGRQKLYFFGPTIFVVCSLAQFWADSGAALFFFRFLIGVGV
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GFEYPVAGSLLVEFMPRKDRGPRLAMLTILWFAGAALAYMVGNAILDTGRADAWRLVLAS
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
PAVIGALLLLVRIGTPESPRWLLSKGRAAEAERVIQQVYGPQFSLENLPEQRPEKKVSLL
HHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHH
SLLHSGYGKRMLFVSVFWSCSVIPVFAVYAFAPTVLQALHLKGAWASFGSVAITLLFVVG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
CFVATRLINTVGRRSMLIHSFLWSGLALLGLGLFCDGSEMLVLVLFGAYAVFIGGAQVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHH
LVYPNELFPTEIRSAAVGMGASLSRIGAAIGTWAVPVALQGIGVGNTMFAAAGVTLFGLL
HHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VSLAIAPETRALSLQEAASLSR
HHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANNVSIEDVPLNGFHQLLSIRSGGGWVLDGYVLSIIGVAMVQLSAALHLSGFWQGMVAA
CCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALIGIFCGGFLGGLLTGCLGRQKLYFFGPTIFVVCSLAQFWADSGAALFFFRFLIGVGV
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GFEYPVAGSLLVEFMPRKDRGPRLAMLTILWFAGAALAYMVGNAILDTGRADAWRLVLAS
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
PAVIGALLLLVRIGTPESPRWLLSKGRAAEAERVIQQVYGPQFSLENLPEQRPEKKVSLL
HHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHH
SLLHSGYGKRMLFVSVFWSCSVIPVFAVYAFAPTVLQALHLKGAWASFGSVAITLLFVVG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
CFVATRLINTVGRRSMLIHSFLWSGLALLGLGLFCDGSEMLVLVLFGAYAVFIGGAQVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHH
LVYPNELFPTEIRSAAVGMGASLSRIGAAIGTWAVPVALQGIGVGNTMFAAAGVTLFGLL
HHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VSLAIAPETRALSLQEAASLSR
HHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]