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The map label for this gene is dapA [H]

Identifier: 17546830

GI number: 17546830

Start: 2286111

End: 2287019

Strand: Reverse

Name: dapA [H]

Synonym: RSc2111

Alternate gene names: 17546830

Gene position: 2287019-2286111 (Counterclockwise)

Preceding gene: 17546831

Following gene: 17546829

Centisome position: 61.54

GC content: 65.46

Gene sequence:

>909_bases
ATGAAATTCGAAGGCATCTACACGCCCGCAATCACACCCCTGACGCAAGAGGGGAACATCGACAAAGGCGCCTTTGCCGA
AGTCCTGGAATCCCTGCTGGATGCCAACGTCCACGGCATCGTCATCGGGGGCTCGACCGGCGAATACTATGCGCACACGC
CGCAGGAGCGTTTTGAACTCGCCGCGCTCGCCAAGTCGGTGATCGGTACGCGTGTGCCGCTGGTGGTCGGCACCGGAGCC
GTGCGCACCGAAGATTCGGTCGAGTATGCCAAGGCGGCCAAGGCCATCAAGGCCGACGCGATTCTCGTCGGCTCGCCGCC
GTACGCGCTGCCGACCGAGCGCGAGAACGCGGCCCACGCGCTCACGATCGACCGGGCGGCGGGCCTGCCCATCATGCTCT
ACAACTATCCCGGGCGGATGAGCGTGTCGATGGGCCGCGAGTTCTTCAGCACCGTCTCGGCCGCCTCCAGCAACTTCGTT
GCGATCAAGGAGAGCTCCGGCCAGACGGCACAGCTGCACATGCTGGCCGCGGCGTTCCCGAACATCGGCATCTCGTGCGG
CTGGGACGACCAGGCGCTGGAGTTCTTCGCCTGGGGCGCCCGCAGCTGGGTGTGCGCGGGCTCGAACTTCATCCCGCACG
AGCATATCGCGCTGTACGAAGCCTGCGTCATCGAAAAGAATTTCGACAAGGGCCGCCGCATCATGGCGGCGATGCTGCCG
TTGATGGATTTCCTGGAAGGCGGGAAATTCGTGCAGTCCATCAAGTTCGGCTGCGAACTGGCCGGACTGCGTTCGGGCGG
GGTGCGGGCCCCGCTGGCGTCGCTCGACGAGAGCGAGAAGCAGACGCTGCAAGCCATCGTCGCCCGGCTGCGGCACGATG
TCGCCACGGTCGTCGCGGAGGGCGTCTGA

Upstream 100 bases:

>100_bases
TTCGCTCAGTCGCTAGTTTCCCCGTGTCGCCGGTGGCGCGACCGGCGACGCAGTCTCTTCCTTGAAAACGACGCTTCCGC
TTGAACGGAGAAAAGCAATC

Downstream 100 bases:

>100_bases
TGGCTCAACTTCTGACCGTATCCGAATACGCCGCGATGGCCGGGAAGCTCGCGCTGCCGACGCAGGCGTTCATCGATGGC
GCTTTTGTGCCCGCCGTGTC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKFEGIYTPAITPLTQEGNIDKGAFAEVLESLLDANVHGIVIGGSTGEYYAHTPQERFELAALAKSVIGTRVPLVVGTGA
VRTEDSVEYAKAAKAIKADAILVGSPPYALPTERENAAHALTIDRAAGLPIMLYNYPGRMSVSMGREFFSTVSAASSNFV
AIKESSGQTAQLHMLAAAFPNIGISCGWDDQALEFFAWGARSWVCAGSNFIPHEHIALYEACVIEKNFDKGRRIMAAMLP
LMDFLEGGKFVQSIKFGCELAGLRSGGVRAPLASLDESEKQTLQAIVARLRHDVATVVAEGV

Sequences:

>Translated_302_residues
MKFEGIYTPAITPLTQEGNIDKGAFAEVLESLLDANVHGIVIGGSTGEYYAHTPQERFELAALAKSVIGTRVPLVVGTGA
VRTEDSVEYAKAAKAIKADAILVGSPPYALPTERENAAHALTIDRAAGLPIMLYNYPGRMSVSMGREFFSTVSAASSNFV
AIKESSGQTAQLHMLAAAFPNIGISCGWDDQALEFFAWGARSWVCAGSNFIPHEHIALYEACVIEKNFDKGRRIMAAMLP
LMDFLEGGKFVQSIKFGCELAGLRSGGVRAPLASLDESEKQTLQAIVARLRHDVATVVAEGV
>Mature_302_residues
MKFEGIYTPAITPLTQEGNIDKGAFAEVLESLLDANVHGIVIGGSTGEYYAHTPQERFELAALAKSVIGTRVPLVVGTGA
VRTEDSVEYAKAAKAIKADAILVGSPPYALPTERENAAHALTIDRAAGLPIMLYNYPGRMSVSMGREFFSTVSAASSNFV
AIKESSGQTAQLHMLAAAFPNIGISCGWDDQALEFFAWGARSWVCAGSNFIPHEHIALYEACVIEKNFDKGRRIMAAMLP
LMDFLEGGKFVQSIKFGCELAGLRSGGVRAPLASLDESEKQTLQAIVARLRHDVATVVAEGV

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=304, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786463, Length=287, Percent_Identity=28.9198606271777, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082415, Length=273, Percent_Identity=28.2051282051282, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=22.680412371134, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789620, Length=199, Percent_Identity=26.1306532663317, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32310; Mature: 32310

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFEGIYTPAITPLTQEGNIDKGAFAEVLESLLDANVHGIVIGGSTGEYYAHTPQERFEL
CCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHH
AALAKSVIGTRVPLVVGTGAVRTEDSVEYAKAAKAIKADAILVGSPPYALPTERENAAHA
HHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEE
LTIDRAAGLPIMLYNYPGRMSVSMGREFFSTVSAASSNFVAIKESSGQTAQLHMLAAAFP
EEEECCCCCCEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCEEHEEEHHHHCC
NIGISCGWDDQALEFFAWGARSWVCAGSNFIPHEHIALYEACVIEKNFDKGRRIMAAMLP
CCCEECCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LMDFLEGGKFVQSIKFGCELAGLRSGGVRAPLASLDESEKQTLQAIVARLRHDVATVVAE
HHHHHCCCHHHHHHHHCCEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
GV
CC
>Mature Secondary Structure
MKFEGIYTPAITPLTQEGNIDKGAFAEVLESLLDANVHGIVIGGSTGEYYAHTPQERFEL
CCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHH
AALAKSVIGTRVPLVVGTGAVRTEDSVEYAKAAKAIKADAILVGSPPYALPTERENAAHA
HHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEE
LTIDRAAGLPIMLYNYPGRMSVSMGREFFSTVSAASSNFVAIKESSGQTAQLHMLAAAFP
EEEECCCCCCEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCEEHEEEHHHHCC
NIGISCGWDDQALEFFAWGARSWVCAGSNFIPHEHIALYEACVIEKNFDKGRRIMAAMLP
CCCEECCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LMDFLEGGKFVQSIKFGCELAGLRSGGVRAPLASLDESEKQTLQAIVARLRHDVATVVAE
HHHHHCCCHHHHHHHHCCEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA