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The map label for this gene is glnP [H]

Identifier: 17546823

GI number: 17546823

Start: 2279232

End: 2279978

Strand: Direct

Name: glnP [H]

Synonym: RSc2104

Alternate gene names: 17546823

Gene position: 2279232-2279978 (Clockwise)

Preceding gene: 17546822

Following gene: 17546824

Centisome position: 61.33

GC content: 64.93

Gene sequence:

>747_bases
ATGGCATATCAATTCGACTTTGGCGCCGTCTTCAGTTACAGCGGCCAGTTGGCGCAGGGCGCCGGCTTTACGCTCGCGCT
CACGGCGGCGGGCGCTGTGCTCGGCGGCGCCATCGGCTTGGCTGGGGGCGTGTGCCGCGCCTGGCGCATCGCGCCCTTTA
ACGGGCTGTTCAAGGTGTATGTGGAGGCCATCCGCAACACGCCCTTCCTGATTCAGCTGATGTTCGTGTTCTTCGGCTTG
CCCTCGCTGGGCCTGCAGATCAACGAATGGCAAGCCGCCTTGCTCACAACGGTGGTCAACCTGGGGGCCTACATCACCGA
GATCGTGCGCGCGGGCATCCAGGAAACACCGCGTGGCCAGTTGGAAGCTGCCAGCGCGCTGGCCATGAGCCGCTGGACGT
GCTTTCGTCATGTGGTGTTGCGGCCGGCGCTGCAGAAGGTCTGGCCGGCACTGAGCAGCCAGATCGTGATCGTGATGCTG
GGCACCTCGGTGGTCTCGCAGATCGCCGCGCAGGACCTGACCTTTGCCGCCAACTTCATCCAGTCGCGCAACTTCCGCGC
CTTTGAAACCTATCTGGTGGTCACGGCGCTGTACTTCGCGCTGGCCCTGTTGCTGCGTCAGTTGCTGGCCTGGATTGCCC
AGCGCTTTGTCGTGGTTCGCCGCACACCGGCTGCACCTGCCTCAGCGGCCGCACCTGCGGCAGCACGCACAGCCACAGCC
ACCACCTCAGCCCGGAACGCCGCATGA

Upstream 100 bases:

>100_bases
CAGCGCTGGATCAAGATGCCGCTGCCCGCAAAACTGTAAGCAACGCCTTCGTAACGCAGGCCTGCCGCACGCGCGGTCGT
GCGGCATCCGGAACACCTCA

Downstream 100 bases:

>100_bases
TTGCCGATATCCCTTTGCTGCCCATCCTCCTCAAACTCAGTGAGGGGCTGCTTGCCACGCTGTTGCTGTCGTTGATGGCC
TTCGCTCTGGGTGGCGCGGC

Product: amino-acid transmembrane ABC transporter protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MAYQFDFGAVFSYSGQLAQGAGFTLALTAAGAVLGGAIGLAGGVCRAWRIAPFNGLFKVYVEAIRNTPFLIQLMFVFFGL
PSLGLQINEWQAALLTTVVNLGAYITEIVRAGIQETPRGQLEAASALAMSRWTCFRHVVLRPALQKVWPALSSQIVIVML
GTSVVSQIAAQDLTFAANFIQSRNFRAFETYLVVTALYFALALLLRQLLAWIAQRFVVVRRTPAAPASAAAPAAARTATA
TTSARNAA

Sequences:

>Translated_248_residues
MAYQFDFGAVFSYSGQLAQGAGFTLALTAAGAVLGGAIGLAGGVCRAWRIAPFNGLFKVYVEAIRNTPFLIQLMFVFFGL
PSLGLQINEWQAALLTTVVNLGAYITEIVRAGIQETPRGQLEAASALAMSRWTCFRHVVLRPALQKVWPALSSQIVIVML
GTSVVSQIAAQDLTFAANFIQSRNFRAFETYLVVTALYFALALLLRQLLAWIAQRFVVVRRTPAAPASAAAPAAARTATA
TTSARNAA
>Mature_247_residues
AYQFDFGAVFSYSGQLAQGAGFTLALTAAGAVLGGAIGLAGGVCRAWRIAPFNGLFKVYVEAIRNTPFLIQLMFVFFGLP
SLGLQINEWQAALLTTVVNLGAYITEIVRAGIQETPRGQLEAASALAMSRWTCFRHVVLRPALQKVWPALSSQIVIVMLG
TSVVSQIAAQDLTFAANFIQSRNFRAFETYLVVTALYFALALLLRQLLAWIAQRFVVVRRTPAAPASAAAPAAARTATAT
TSARNAA

Specific function: Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=218, Percent_Identity=34.8623853211009, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1788226, Length=192, Percent_Identity=31.25, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=28.8288288288288, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788646, Length=226, Percent_Identity=26.1061946902655, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786874, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787087, Length=240, Percent_Identity=24.1666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788645, Length=205, Percent_Identity=24.390243902439, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994930, Length=136, Percent_Identity=30.8823529411765, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI87082239, Length=160, Percent_Identity=31.875, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1787086, Length=213, Percent_Identity=24.4131455399061, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26562; Mature: 26431

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQFDFGAVFSYSGQLAQGAGFTLALTAAGAVLGGAIGLAGGVCRAWRIAPFNGLFKVY
CCEECCCCHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VEAIRNTPFLIQLMFVFFGLPSLGLQINEWQAALLTTVVNLGAYITEIVRAGIQETPRGQ
HHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LEAASALAMSRWTCFRHVVLRPALQKVWPALSSQIVIVMLGTSVVSQIAAQDLTFAANFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH
QSRNFRAFETYLVVTALYFALALLLRQLLAWIAQRFVVVRRTPAAPASAAAPAAARTATA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
TTSARNAA
CCCCCCCC
>Mature Secondary Structure 
AYQFDFGAVFSYSGQLAQGAGFTLALTAAGAVLGGAIGLAGGVCRAWRIAPFNGLFKVY
CEECCCCHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VEAIRNTPFLIQLMFVFFGLPSLGLQINEWQAALLTTVVNLGAYITEIVRAGIQETPRGQ
HHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LEAASALAMSRWTCFRHVVLRPALQKVWPALSSQIVIVMLGTSVVSQIAAQDLTFAANFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH
QSRNFRAFETYLVVTALYFALALLLRQLLAWIAQRFVVVRRTPAAPASAAAPAAARTATA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
TTSARNAA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]