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The map label for this gene is nahR [H]

Identifier: 17546737

GI number: 17546737

Start: 2196578

End: 2197543

Strand: Reverse

Name: nahR [H]

Synonym: RSc2018

Alternate gene names: 17546737

Gene position: 2197543-2196578 (Counterclockwise)

Preceding gene: 17546743

Following gene: 17546736

Centisome position: 59.13

GC content: 71.84

Gene sequence:

>966_bases
TTGCCATCCATCAATATCGTGCATATTTCGCGGGTCGACCTCAACCTGTTCGTCGTCTTTGACGCCATCTACAGCGAAGG
CGGCATCACCGCGGCCGCGCGCACGCTCAACCTGACGCAGCCGGCCGTCAGCCACGCGCTGGGGCGGCTGCGCGAGCTGT
TCGACGATCCGCTGTTCGAGCGGCGCGGGCAGGGCATGGTGCCGACGCCGCTGGCCCGCACGCTGGTCGCCGAGGTGCGC
GCCGCGTTGCAGGGCTTCGAGCGCACGCTGCGCGAAGGCACGCGCTTCGATCCGGCCGCCAGCGAGCGCCGCTTCACGCT
GTCGATGCGCGATGCGCTGGAAGCGACGCTGCTGCCGCCGCTGATGGCCGCCATCGCCCGCGAGGCGCCGCGCATCGATG
TGACCACCGTGCGCGGCGACCGCCGCCAGCTCGAAGCCGAACTGCTCGCCGGCACCATCGATGCGGCGGTCGACATCCTG
CTGCCGGTGTCGCCGGCCATCCGCCACGCGCCCCTGCTGTCGGACCCGATGGTGGTGCTGGCGCGGCCTGGCCATCCGGT
CACGCAGGGGCCGCTGACACTGGAGCGCTACCTGGCCTACGAGCACGTGCACGTGTCATCGCGCCGGCGCGGCGCGGGGC
TGGAGGACGTGGAGCTGCGCCGGCTCGGGCGCGAGCGGCGCGTGCGGCTGCGCTGCCAGCATTACCCGGCGGCGTGTCGC
GTGGTCAGCTGCACCGACCTGCTGGTGACGCTGCCGGTGCGCTATGCGCGCATCGCCAACGCGCCGTACGGCAACGTGAT
GCTGCCGCTGCCGTTCAAGGTGCCGCCGCTGGAGCTCTACCTGTACTGGCACGCCAACAGTGACCAGGATGCCGCCGGCC
GCTGGCTGCGCGATCACGTACTCGCCGCGATGGCCGGCGTGGCCGAAGACGAGGCTGCCGCGGCGCTCGCCGGCAGGAAC
GCATAG

Upstream 100 bases:

>100_bases
ACGGTCAGGTTGGCGGCGGAGGTCATGGCGGGCACGACGGCAAACACGGATGCCCGCAGCATAAGCGCTCGCCTAAAATA
AGAGAAATGAATTTCGTGGA

Downstream 100 bases:

>100_bases
CGGGCGGCCGGCTGGACGAACGGCCGCAATCGGCCTACGGTCTTTCCATCCCCGGGGGCGGCGTCATGGTGTCCGGTGCA
TCGCGGCAGCCGGTGCGGCC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MPSINIVHISRVDLNLFVVFDAIYSEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGMVPTPLARTLVAEVR
AALQGFERTLREGTRFDPAASERRFTLSMRDALEATLLPPLMAAIAREAPRIDVTTVRGDRRQLEAELLAGTIDAAVDIL
LPVSPAIRHAPLLSDPMVVLARPGHPVTQGPLTLERYLAYEHVHVSSRRRGAGLEDVELRRLGRERRVRLRCQHYPAACR
VVSCTDLLVTLPVRYARIANAPYGNVMLPLPFKVPPLELYLYWHANSDQDAAGRWLRDHVLAAMAGVAEDEAAAALAGRN
A

Sequences:

>Translated_321_residues
MPSINIVHISRVDLNLFVVFDAIYSEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGMVPTPLARTLVAEVR
AALQGFERTLREGTRFDPAASERRFTLSMRDALEATLLPPLMAAIAREAPRIDVTTVRGDRRQLEAELLAGTIDAAVDIL
LPVSPAIRHAPLLSDPMVVLARPGHPVTQGPLTLERYLAYEHVHVSSRRRGAGLEDVELRRLGRERRVRLRCQHYPAACR
VVSCTDLLVTLPVRYARIANAPYGNVMLPLPFKVPPLELYLYWHANSDQDAAGRWLRDHVLAAMAGVAEDEAAAALAGRN
A
>Mature_320_residues
PSINIVHISRVDLNLFVVFDAIYSEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGMVPTPLARTLVAEVRA
ALQGFERTLREGTRFDPAASERRFTLSMRDALEATLLPPLMAAIAREAPRIDVTTVRGDRRQLEAELLAGTIDAAVDILL
PVSPAIRHAPLLSDPMVVLARPGHPVTQGPLTLERYLAYEHVHVSSRRRGAGLEDVELRRLGRERRVRLRCQHYPAACRV
VSCTDLLVTLPVRYARIANAPYGNVMLPLPFKVPPLELYLYWHANSDQDAAGRWLRDHVLAAMAGVAEDEAAAALAGRNA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=291, Percent_Identity=31.9587628865979, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081766, Length=271, Percent_Identity=26.1992619926199, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=27.1523178807947, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786820, Length=286, Percent_Identity=23.7762237762238, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787601, Length=285, Percent_Identity=23.5087719298246, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35413; Mature: 35282

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSINIVHISRVDLNLFVVFDAIYSEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFE
CCCCEEEEEEEECEEEEEEEEHHHCCCCCEEHHHEECCCHHHHHHHHHHHHHHHCCHHHH
RRGQGMVPTPLARTLVAEVRAALQGFERTLREGTRFDPAASERRFTLSMRDALEATLLPP
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
LMAAIAREAPRIDVTTVRGDRRQLEAELLAGTIDAAVDILLPVSPAIRHAPLLSDPMVVL
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEE
ARPGHPVTQGPLTLERYLAYEHVHVSSRRRGAGLEDVELRRLGRERRVRLRCQHYPAACR
ECCCCCCCCCCHHHHHHHHHHHHECCCCCCCCCCCHHHHHHCCHHHHEEEEECCCCCCEE
VVSCTDLLVTLPVRYARIANAPYGNVMLPLPFKVPPLELYLYWHANSDQDAAGRWLRDHV
EEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHH
LAAMAGVAEDEAAAALAGRNA
HHHHHCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
PSINIVHISRVDLNLFVVFDAIYSEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFE
CCCEEEEEEEECEEEEEEEEHHHCCCCCEEHHHEECCCHHHHHHHHHHHHHHHCCHHHH
RRGQGMVPTPLARTLVAEVRAALQGFERTLREGTRFDPAASERRFTLSMRDALEATLLPP
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
LMAAIAREAPRIDVTTVRGDRRQLEAELLAGTIDAAVDILLPVSPAIRHAPLLSDPMVVL
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEE
ARPGHPVTQGPLTLERYLAYEHVHVSSRRRGAGLEDVELRRLGRERRVRLRCQHYPAACR
ECCCCCCCCCCHHHHHHHHHHHHECCCCCCCCCCCHHHHHHCCHHHHEEEEECCCCCCEE
VVSCTDLLVTLPVRYARIANAPYGNVMLPLPFKVPPLELYLYWHANSDQDAAGRWLRDHV
EEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHH
LAAMAGVAEDEAAAALAGRNA
HHHHHCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]