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The map label for this gene is 17546727

Identifier: 17546727

GI number: 17546727

Start: 2187253

End: 2188398

Strand: Reverse

Name: 17546727

Synonym: RSc2008

Alternate gene names: NA

Gene position: 2188398-2187253 (Counterclockwise)

Preceding gene: 17546728

Following gene: 17546716

Centisome position: 58.88

GC content: 69.02

Gene sequence:

>1146_bases
ATGACCGCCACCCAGCCGTATCTCTCCAGCACGTTCGACAGCGGCGCCATCGAGATCGTCGATGCCGCGCGCGCCGACGC
CATCCGGCTGCGCATCCGCCGCGATTCGCACGCGGACTTCACGCAGTGGTTCCACTTCCGCCTGCAGGGCGTGCAGGGGC
AGGCGTGCCGGCTGGTGCTGGAGAACGCCGGCGAGTGCACGTACCCGGCCGGCTGGAAGGACTACCAGGCCGTCGCGTCC
TACGACCGGCAGCACTGGTTCCGCGTGCCGACGCGCTACGACGGCCGGGCGCTCACCATCGAGCTCACGCCCGAGCACGA
CAGCCTCTGGTTCGCCTATTTCGAGCCGTATCCCGATGAGCGCCACCTGTCGCTGGTGGCCGCGGCGCAAGCCGCGCCGG
GTGTGCGCACGCGGCGCCTGGGGCAGACGGTGCAGGGCCGCGACATGACCTGCATCACCGTGGGCGAGCCCGGTCCGGGC
AAGAAGACGGTGTGGCTCATCGCGCGCCAGCATCCGGGTGAAACGATGGCCGAGTGGTTCGTCGAAGGGCTGCTCGCCCG
CCTGACGCGCCAGGGCGCATGGCGCGGTGACCCGCTGGGCCGCGTGCTGGCCGAACGCACCGTTTTCCACATCGTGCCGA
ACATGAACCCTGATGGTTCGTCGCTCGGCAACCTGCGCACCAACGCCGCCGGCGCCAACCTGAACCGCGAGTGGATGGAG
CCGAACGCCGAGACCAGCCCCGAAGTCCTGTGCGTGCGCCAGGCCATCGAAGCCACCGGCGTCGACCTGTTCTTCGACAT
CCACGGCGATGAGGCGCTGCCCTACGTGTTCATCGCGGGCAGCGAGATGCTGCCGGGCTTCACCGACGCCCAGCGCGCCG
ATCAGGCACGCTTCGCCGCGGCGTTCCTGCGTGCCTCGCCCGATTTCCAGACACGGTTCGGCTACGAGGCCAGCAAGTAC
GACCAGGACGCGCTCAAGCTGGCCTCCAAGTACATCGGCCACACCTTCGGCTGCCTGTCGCTGACGCTGGAAATGCCGTT
CAAGGACAACGCCAACCTGCCCGATGCCCGGGTCGGCTGGGATGGTGCCCGCAGCGCCGCGCTGGGCGCGGCCATGCTGC
AGGCGATTCTCGAATATCTGGGCTGA

Upstream 100 bases:

>100_bases
AAGGCTACGCGTTTGCCGCCGAAGCCTCCGACGATGAGCGCTGGGTCTTCCGCCGCAAGGCCGCCTGATTTCTCCCGCAT
CGCGCACCACAGGATTGCCC

Downstream 100 bases:

>100_bases
ACGGCGCGGCCTGGGGCCGATGCGGAGCCGATGCCGCCGCGGTTCCGGCGGCATCGGCTTGAGCTGTCAGCCGGCGTTCG
ACTTCTTGGTCTTCTTGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTATQPYLSSTFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACRLVLENAGECTYPAGWKDYQAVAS
YDRQHWFRVPTRYDGRALTIELTPEHDSLWFAYFEPYPDERHLSLVAAAQAAPGVRTRRLGQTVQGRDMTCITVGEPGPG
KKTVWLIARQHPGETMAEWFVEGLLARLTRQGAWRGDPLGRVLAERTVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
PNAETSPEVLCVRQAIEATGVDLFFDIHGDEALPYVFIAGSEMLPGFTDAQRADQARFAAAFLRASPDFQTRFGYEASKY
DQDALKLASKYIGHTFGCLSLTLEMPFKDNANLPDARVGWDGARSAALGAAMLQAILEYLG

Sequences:

>Translated_381_residues
MTATQPYLSSTFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACRLVLENAGECTYPAGWKDYQAVAS
YDRQHWFRVPTRYDGRALTIELTPEHDSLWFAYFEPYPDERHLSLVAAAQAAPGVRTRRLGQTVQGRDMTCITVGEPGPG
KKTVWLIARQHPGETMAEWFVEGLLARLTRQGAWRGDPLGRVLAERTVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
PNAETSPEVLCVRQAIEATGVDLFFDIHGDEALPYVFIAGSEMLPGFTDAQRADQARFAAAFLRASPDFQTRFGYEASKY
DQDALKLASKYIGHTFGCLSLTLEMPFKDNANLPDARVGWDGARSAALGAAMLQAILEYLG
>Mature_380_residues
TATQPYLSSTFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACRLVLENAGECTYPAGWKDYQAVASY
DRQHWFRVPTRYDGRALTIELTPEHDSLWFAYFEPYPDERHLSLVAAAQAAPGVRTRRLGQTVQGRDMTCITVGEPGPGK
KTVWLIARQHPGETMAEWFVEGLLARLTRQGAWRGDPLGRVLAERTVFHIVPNMNPDGSSLGNLRTNAAGANLNREWMEP
NAETSPEVLCVRQAIEATGVDLFFDIHGDEALPYVFIAGSEMLPGFTDAQRADQARFAAAFLRASPDFQTRFGYEASKYD
QDALKLASKYIGHTFGCLSLTLEMPFKDNANLPDARVGWDGARSAALGAAMLQAILEYLG

Specific function: Unknown

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI190194403, Length=375, Percent_Identity=28.2666666666667, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI31657119, Length=310, Percent_Identity=27.4193548387097, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI170763513, Length=326, Percent_Identity=24.5398773006135, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI222352158, Length=347, Percent_Identity=24.207492795389, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI120444924, Length=328, Percent_Identity=26.219512195122, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI78482633, Length=109, Percent_Identity=33.9449541284404, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI118421091, Length=109, Percent_Identity=33.9449541284404, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533904, Length=412, Percent_Identity=23.3009708737864, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193202888, Length=190, Percent_Identity=31.0526315789474, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571179, Length=239, Percent_Identity=28.4518828451883, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24641847, Length=239, Percent_Identity=28.4518828451883, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI161077807, Length=239, Percent_Identity=28.4518828451883, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641845, Length=238, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 42336; Mature: 42205

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATQPYLSSTFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACRLVL
CCCCCCCHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHH
ENAGECTYPAGWKDYQAVASYDRQHWFRVPTRYDGRALTIELTPEHDSLWFAYFEPYPDE
HCCCCCCCCCCCHHHHHHHHHCHHHEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCCC
RHLSLVAAAQAAPGVRTRRLGQTVQGRDMTCITVGEPGPGKKTVWLIARQHPGETMAEWF
CCEEEEEHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHH
VEGLLARLTRQGAWRGDPLGRVLAERTVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
HHHHHHHHHHCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCC
PNAETSPEVLCVRQAIEATGVDLFFDIHGDEALPYVFIAGSEMLPGFTDAQRADQARFAA
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
AFLRASPDFQTRFGYEASKYDQDALKLASKYIGHTFGCLSLTLEMPFKDNANLPDARVGW
HHHHCCCCCHHHCCCCHHHCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCC
DGARSAALGAAMLQAILEYLG
CCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TATQPYLSSTFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACRLVL
CCCCCCHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHH
ENAGECTYPAGWKDYQAVASYDRQHWFRVPTRYDGRALTIELTPEHDSLWFAYFEPYPDE
HCCCCCCCCCCCHHHHHHHHHCHHHEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCCC
RHLSLVAAAQAAPGVRTRRLGQTVQGRDMTCITVGEPGPGKKTVWLIARQHPGETMAEWF
CCEEEEEHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHH
VEGLLARLTRQGAWRGDPLGRVLAERTVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
HHHHHHHHHHCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCC
PNAETSPEVLCVRQAIEATGVDLFFDIHGDEALPYVFIAGSEMLPGFTDAQRADQARFAA
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
AFLRASPDFQTRFGYEASKYDQDALKLASKYIGHTFGCLSLTLEMPFKDNANLPDARVGW
HHHHCCCCCHHHCCCCHHHCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCC
DGARSAALGAAMLQAILEYLG
CCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8320209 [H]