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The map label for this gene is yhcK [H]

Identifier: 17546612

GI number: 17546612

Start: 2078915

End: 2080516

Strand: Reverse

Name: yhcK [H]

Synonym: RSc1893

Alternate gene names: 17546612

Gene position: 2080516-2078915 (Counterclockwise)

Preceding gene: 17546613

Following gene: 17546609

Centisome position: 55.98

GC content: 67.67

Gene sequence:

>1602_bases
ATGGGGCTGGGCGGATTGATTCTGCTGCTGGCCCTGGGTTCGGTGCTGCTGACCATGGCGAACGCCATGTATTCCAGTTA
TCGCACGCAGCGCGATCTGCTGATCCGGAATGCGCTGGAAGCCAACCGCGTCTATGCGGCCAAGCTGGCCGAGTCGACCG
ATTTGGCCATCGGCGTCACGCGGCAGGAGTTGGCCTATGGCGCGGGCCTCCTGGCCGCGCACATGGAGGATCCCGCGCGG
CTGACGGAAGAGGCCGAGCGGTTGCGCCAGCAGATGGGCAGCCTCAACTCGGTCGTCATCGTGCGCCGCGACGGCGCGGT
CATCGGGGCTTCGCCGGCCAGCCTGCAGCTGAAATCCATGCGCAGCGACTGGGGCCGCCGGCTGCTCGATTCCCGCATTC
CCGAGATCAGCCGGCCGTTCCGGGCGCCGACGGGCCGGCTGCTCATCTTCCTGTCCCATCCCGTGATCGATGGCCAGGGG
CGCCTGCTGGGCTATGTCGGCGGCACGATCTATCTGAACGAGAAGAACCTCCTCCACACGATCTTCGTCCATCACTACTA
TCGCGACGGTTCGTATATCTATGTCGTCGATCGCGATGGCACGGTCATCTACCATCCGAACAGCGGCTATGTCGGCGATA
TGACCGGCGCGAACCCGGCGGTGGCCGAAGTGATGCTGGGACATGCGGGGGCGCAGCGCATCCGGAGCCTGCACGGGATC
GACATGCTGGCCGGCTATGCGCCGGTGGCGTCGACGGGGTGGGGCATCGTGGCGCAGAAGCCCACCGAGACAACGCTGAG
CGATCTCAATGGCCTGATGCTGGTGACCCTGTCGCACAGCATTCCGTTGTTCGTGCTGTCCATCGTCTTCATCTGGTGGT
TTGCCAGGTCGATCTCCCGCCCGCTCGTCGAGCTGGCCAGCCAGGCCCGGCTGGTGGCGACGCCGGAGCGCCTGGAGCGG
ATCAAGACCGTGTCTTCCTGGTACATCGAAGCCCATCGTCTCAAGCGCGCGCTGCTGCGCGGCACGCGCCTGACCAGCAC
TCGCATGGCCAGGCTCAACCTCGAGGCGCTCACCGATCCCCTGACCGGCCTGTACAACCGCCGCGGCGTCGCGAATGCGC
TGCGCCTGCACGCGGGGCGGCACCAGCCGTTTTCGGCCGTCACGCTGGACGTCGATCACTTCAAGCGGATCAACGACCGG
CACGGGCACGATGTCGGCGACCAGGTGCTCCGGCACCTTGCCGCGCTGATCCGGGAGCAGGCCAGGCATGGCGATATCAC
CGGCCGCATCGGTGGGGAGGAGTTCATCCTCCTGCTGCCCGACGCCACGCCGGACGGTGCCTTCAGGACGGCCGAGCGGC
TGCGCCTGGCCGTGGAGGCGCGGCCGAACCCGGCGGGGCAGGTGGTCACGGTCTCGCTCGGGGTGGCGCACTATCCGCAG
TCAGCGGGGGAGGTCGATGCCGTCCTGAAACTGTCCGATCTTGCGCTCTATCAGGCCAAGCGCGACGGGCGCAACCGGAC
CGTGGTCTACCAGGCGGAGCGTGCGGACGGGCCCGCCGACCTGGAGCCGGCCTCGCGGGCACGGGCTGAGGAGGGCGGCT
GA

Upstream 100 bases:

>100_bases
GCTGAAACACTTGGGGCCATGCTACGATGCCTCAACTCTTGTTTCGGCACGACCGATGCCTGTGCAATCGCGCTTTCGTC
TCGCCAGGGGCGCGCCGAGG

Downstream 100 bases:

>100_bases
GATCGCGGGGCGCTCGGGCGGTGGGCGTCGCGCCGGCGACGCCCGGCCGGCCTCGCTCGCCGGGGCGCCGGGGCGATAAA
AAAGCCCGGGCACGCGGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MGLGGLILLLALGSVLLTMANAMYSSYRTQRDLLIRNALEANRVYAAKLAESTDLAIGVTRQELAYGAGLLAAHMEDPAR
LTEEAERLRQQMGSLNSVVIVRRDGAVIGASPASLQLKSMRSDWGRRLLDSRIPEISRPFRAPTGRLLIFLSHPVIDGQG
RLLGYVGGTIYLNEKNLLHTIFVHHYYRDGSYIYVVDRDGTVIYHPNSGYVGDMTGANPAVAEVMLGHAGAQRIRSLHGI
DMLAGYAPVASTGWGIVAQKPTETTLSDLNGLMLVTLSHSIPLFVLSIVFIWWFARSISRPLVELASQARLVATPERLER
IKTVSSWYIEAHRLKRALLRGTRLTSTRMARLNLEALTDPLTGLYNRRGVANALRLHAGRHQPFSAVTLDVDHFKRINDR
HGHDVGDQVLRHLAALIREQARHGDITGRIGGEEFILLLPDATPDGAFRTAERLRLAVEARPNPAGQVVTVSLGVAHYPQ
SAGEVDAVLKLSDLALYQAKRDGRNRTVVYQAERADGPADLEPASRARAEEGG

Sequences:

>Translated_533_residues
MGLGGLILLLALGSVLLTMANAMYSSYRTQRDLLIRNALEANRVYAAKLAESTDLAIGVTRQELAYGAGLLAAHMEDPAR
LTEEAERLRQQMGSLNSVVIVRRDGAVIGASPASLQLKSMRSDWGRRLLDSRIPEISRPFRAPTGRLLIFLSHPVIDGQG
RLLGYVGGTIYLNEKNLLHTIFVHHYYRDGSYIYVVDRDGTVIYHPNSGYVGDMTGANPAVAEVMLGHAGAQRIRSLHGI
DMLAGYAPVASTGWGIVAQKPTETTLSDLNGLMLVTLSHSIPLFVLSIVFIWWFARSISRPLVELASQARLVATPERLER
IKTVSSWYIEAHRLKRALLRGTRLTSTRMARLNLEALTDPLTGLYNRRGVANALRLHAGRHQPFSAVTLDVDHFKRINDR
HGHDVGDQVLRHLAALIREQARHGDITGRIGGEEFILLLPDATPDGAFRTAERLRLAVEARPNPAGQVVTVSLGVAHYPQ
SAGEVDAVLKLSDLALYQAKRDGRNRTVVYQAERADGPADLEPASRARAEEGG
>Mature_532_residues
GLGGLILLLALGSVLLTMANAMYSSYRTQRDLLIRNALEANRVYAAKLAESTDLAIGVTRQELAYGAGLLAAHMEDPARL
TEEAERLRQQMGSLNSVVIVRRDGAVIGASPASLQLKSMRSDWGRRLLDSRIPEISRPFRAPTGRLLIFLSHPVIDGQGR
LLGYVGGTIYLNEKNLLHTIFVHHYYRDGSYIYVVDRDGTVIYHPNSGYVGDMTGANPAVAEVMLGHAGAQRIRSLHGID
MLAGYAPVASTGWGIVAQKPTETTLSDLNGLMLVTLSHSIPLFVLSIVFIWWFARSISRPLVELASQARLVATPERLERI
KTVSSWYIEAHRLKRALLRGTRLTSTRMARLNLEALTDPLTGLYNRRGVANALRLHAGRHQPFSAVTLDVDHFKRINDRH
GHDVGDQVLRHLAALIREQARHGDITGRIGGEEFILLLPDATPDGAFRTAERLRLAVEARPNPAGQVVTVSLGVAHYPQS
AGEVDAVLKLSDLALYQAKRDGRNRTVVYQAERADGPADLEPASRARAEEGG

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=199, Percent_Identity=36.1809045226131, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082007, Length=190, Percent_Identity=37.8947368421053, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87081881, Length=154, Percent_Identity=42.2077922077922, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787802, Length=167, Percent_Identity=35.9281437125749, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=37.037037037037, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=36, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787541, Length=183, Percent_Identity=32.7868852459016, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788381, Length=182, Percent_Identity=35.1648351648352, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=31.9018404907975, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081977, Length=194, Percent_Identity=28.8659793814433, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081974, Length=194, Percent_Identity=31.4432989690722, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 58485; Mature: 58354

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGGLILLLALGSVLLTMANAMYSSYRTQRDLLIRNALEANRVYAAKLAESTDLAIGVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCCEEEECC
RQELAYGAGLLAAHMEDPARLTEEAERLRQQMGSLNSVVIVRRDGAVIGASPASLQLKSM
HHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCHHHHHHH
RSDWGRRLLDSRIPEISRPFRAPTGRLLIFLSHPVIDGQGRLLGYVGGTIYLNEKNLLHT
HHHHHHHHHHHCCCHHCCCCCCCCCCEEEEEECCEECCCCCEEEEECCEEEECCCCCEEE
IFVHHYYRDGSYIYVVDRDGTVIYHPNSGYVGDMTGANPAVAEVMLGHAGAQRIRSLHGI
EEEEHEEECCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
DMLAGYAPVASTGWGIVAQKPTETTLSDLNGLMLVTLSHSIPLFVLSIVFIWWFARSISR
HHHHCCCCCCCCCCCEEECCCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
PLVELASQARLVATPERLERIKTVSSWYIEAHRLKRALLRGTRLTSTRMARLNLEALTDP
HHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEHHHHHHH
LTGLYNRRGVANALRLHAGRHQPFSAVTLDVDHFKRINDRHGHDVGDQVLRHLAALIREQ
HHHHHHCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ARHGDITGRIGGEEFILLLPDATPDGAFRTAERLRLAVEARPNPAGQVVTVSLGVAHYPQ
HHCCCCEEEECCCEEEEEECCCCCCCHHHHHHHHEEEEECCCCCCCCEEEEEECHHHCCC
SAGEVDAVLKLSDLALYQAKRDGRNRTVVYQAERADGPADLEPASRARAEEGG
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
GLGGLILLLALGSVLLTMANAMYSSYRTQRDLLIRNALEANRVYAAKLAESTDLAIGVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCCEEEECC
RQELAYGAGLLAAHMEDPARLTEEAERLRQQMGSLNSVVIVRRDGAVIGASPASLQLKSM
HHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCHHHHHHH
RSDWGRRLLDSRIPEISRPFRAPTGRLLIFLSHPVIDGQGRLLGYVGGTIYLNEKNLLHT
HHHHHHHHHHHCCCHHCCCCCCCCCCEEEEEECCEECCCCCEEEEECCEEEECCCCCEEE
IFVHHYYRDGSYIYVVDRDGTVIYHPNSGYVGDMTGANPAVAEVMLGHAGAQRIRSLHGI
EEEEHEEECCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
DMLAGYAPVASTGWGIVAQKPTETTLSDLNGLMLVTLSHSIPLFVLSIVFIWWFARSISR
HHHHCCCCCCCCCCCEEECCCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
PLVELASQARLVATPERLERIKTVSSWYIEAHRLKRALLRGTRLTSTRMARLNLEALTDP
HHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEHHHHHHH
LTGLYNRRGVANALRLHAGRHQPFSAVTLDVDHFKRINDRHGHDVGDQVLRHLAALIREQ
HHHHHHCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ARHGDITGRIGGEEFILLLPDATPDGAFRTAERLRLAVEARPNPAGQVVTVSLGVAHYPQ
HHCCCCEEEECCCEEEEEECCCCCCCHHHHHHHHEEEEECCCCCCCCEEEEEECHHHCCC
SAGEVDAVLKLSDLALYQAKRDGRNRTVVYQAERADGPADLEPASRARAEEGG
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]