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The map label for this gene is cyoA2 [H]

Identifier: 17546577

GI number: 17546577

Start: 2041647

End: 2042639

Strand: Direct

Name: cyoA2 [H]

Synonym: RSc1858

Alternate gene names: 17546577

Gene position: 2041647-2042639 (Clockwise)

Preceding gene: 17546575

Following gene: 17546578

Centisome position: 54.94

GC content: 65.36

Gene sequence:

>993_bases
ATGCTCAAACCTACCGCTTTGCCGGCAGACAACCCTCCGCAGGGGCGGCTTGCCGCCCCGCCCTCACCCATACCGTCGCG
CCTGGTCGCGCTTGCCCTCGGCGCCCTTGCAAGCCTGCTGCTGAGCGGCTGCAACCTCGAACTGCTGTCGCCGAAGGGCA
GCATCGGCGAGCAGGAGAAATCGCTCATCCTGGTCGCGCTGTTCGTCATGCTGCTGGTCGTCATTCCCGTGATCGTCCTG
ACGCTGTGGTTCGCATGGCGCTACCGCGAGACGAATACGCGCGCGGCGTACGCACCGACCTGGGCGCACTCGACAACGAT
CGAGATCGTCGTCTGGGGCATCCCGTGCCTGATCGTGGCCTTCCTGGGCGTGCTGATCTGGAACACGACGCACAAGCTCG
ATCCCTATCGGCCGCTGGCATCGCAAGTCGAGCCGGTCGAAATCGAGGTCATCGCGCTGAACTGGAAGTGGCTGTTCATC
TATCCCCAGTACGGTGTCGCCTCGCTGAACCAGCTGGCGATCCCGGTCGGCACGCCGATCAACTTCCGCCTGACCGCCGA
GTCGATGATGAACGCGTTCTTCATCCCGCAGCTGGGCAGCATGGTCTATACGATGGCGGGGATGCAGACGCGGCTGCACC
TGATCGCCGACACGCCGGGCGTCTATCTCGGGCAGTCCGCCGCCTACAGCGGTGCCGGCTTCTCCGACATGCATTTCAAG
ACACTGGCCACTTCGCGCGAGGCGTTCGACGCGTGGGTGCGCTCGGCCAAGGCCTCCGCCAACACGCTCGACTTCAAGAC
CTACCGCGGCCTGGAGCGCCCAAGCAACCGGGACGCCGTCACCCTCTTCTCGGCGGTGGCCCCGAAGCTGTTCGATCGCG
TGGTCGACAAATACATGCTGGCCAACGGCCAGGTCTGCCGCGCAGACGGGCCCGAGTCCCTGCAGGCCTTCCAGCCCATC
CCGTCCGCGTCCATCGGGCGCGTGGAGCAATAA

Upstream 100 bases:

>100_bases
CTTGCGCAGCCGGGTGTTTTTCCAGGGCTGCGGCGGTCATTGCTTCGGCCCTGAAGTGAGGGGCATGGATACCCGGTGAT
GCGTAACCACGGTGTCCGAC

Downstream 100 bases:

>100_bases
GCCATGTTCGGAAAACTCAACCTCAATGCCGTCCCGCTCCATGAGCCGATCATCATGGGAACGCTGGCGGCCGTGCTGGT
CCTCGGCGCGGCGCTGATCG

Product: transmembrane cytochrome O ubiquinol oxidase subunit II

Products: NA

Alternate protein names: Cytochrome o subunit 2; Cytochrome o ubiquinol oxidase subunit 2; Oxidase BO(3) subunit 2; Ubiquinol oxidase polypeptide II [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MLKPTALPADNPPQGRLAAPPSPIPSRLVALALGALASLLLSGCNLELLSPKGSIGEQEKSLILVALFVMLLVVIPVIVL
TLWFAWRYRETNTRAAYAPTWAHSTTIEIVVWGIPCLIVAFLGVLIWNTTHKLDPYRPLASQVEPVEIEVIALNWKWLFI
YPQYGVASLNQLAIPVGTPINFRLTAESMMNAFFIPQLGSMVYTMAGMQTRLHLIADTPGVYLGQSAAYSGAGFSDMHFK
TLATSREAFDAWVRSAKASANTLDFKTYRGLERPSNRDAVTLFSAVAPKLFDRVVDKYMLANGQVCRADGPESLQAFQPI
PSASIGRVEQ

Sequences:

>Translated_330_residues
MLKPTALPADNPPQGRLAAPPSPIPSRLVALALGALASLLLSGCNLELLSPKGSIGEQEKSLILVALFVMLLVVIPVIVL
TLWFAWRYRETNTRAAYAPTWAHSTTIEIVVWGIPCLIVAFLGVLIWNTTHKLDPYRPLASQVEPVEIEVIALNWKWLFI
YPQYGVASLNQLAIPVGTPINFRLTAESMMNAFFIPQLGSMVYTMAGMQTRLHLIADTPGVYLGQSAAYSGAGFSDMHFK
TLATSREAFDAWVRSAKASANTLDFKTYRGLERPSNRDAVTLFSAVAPKLFDRVVDKYMLANGQVCRADGPESLQAFQPI
PSASIGRVEQ
>Mature_330_residues
MLKPTALPADNPPQGRLAAPPSPIPSRLVALALGALASLLLSGCNLELLSPKGSIGEQEKSLILVALFVMLLVVIPVIVL
TLWFAWRYRETNTRAAYAPTWAHSTTIEIVVWGIPCLIVAFLGVLIWNTTHKLDPYRPLASQVEPVEIEVIALNWKWLFI
YPQYGVASLNQLAIPVGTPINFRLTAESMMNAFFIPQLGSMVYTMAGMQTRLHLIADTPGVYLGQSAAYSGAGFSDMHFK
TLATSREAFDAWVRSAKASANTLDFKTYRGLERPSNRDAVTLFSAVAPKLFDRVVDKYMLANGQVCRADGPESLQAFQPI
PSASIGRVEQ

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786635, Length=278, Percent_Identity=52.5179856115108, Blast_Score=311, Evalue=4e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012141
- InterPro:   IPR010514
- InterPro:   IPR008972
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR006333 [H]

Pfam domain/function: PF00116 COX2; PF06481 COX_ARM [H]

EC number: 1.10.3.-

Molecular weight: Translated: 36118; Mature: 36118

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPTALPADNPPQGRLAAPPSPIPSRLVALALGALASLLLSGCNLELLSPKGSIGEQEK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
SLILVALFVMLLVVIPVIVLTLWFAWRYRETNTRAAYAPTWAHSTTIEIVVWGIPCLIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECHHHHHHH
FLGVLIWNTTHKLDPYRPLASQVEPVEIEVIALNWKWLFIYPQYGVASLNQLAIPVGTPI
HHHHHHHCCCCCCCCCCHHHHCCCCEEEEEEEEEEEEEEEECCCCCCCHHHEEEECCCCE
NFRLTAESMMNAFFIPQLGSMVYTMAGMQTRLHLIADTPGVYLGQSAAYSGAGFSDMHFK
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCCCCCCCCCCCCCHHH
TLATSREAFDAWVRSAKASANTLDFKTYRGLERPSNRDAVTLFSAVAPKLFDRVVDKYML
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ANGQVCRADGPESLQAFQPIPSASIGRVEQ
CCCCEEECCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLKPTALPADNPPQGRLAAPPSPIPSRLVALALGALASLLLSGCNLELLSPKGSIGEQEK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
SLILVALFVMLLVVIPVIVLTLWFAWRYRETNTRAAYAPTWAHSTTIEIVVWGIPCLIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECHHHHHHH
FLGVLIWNTTHKLDPYRPLASQVEPVEIEVIALNWKWLFIYPQYGVASLNQLAIPVGTPI
HHHHHHHCCCCCCCCCCHHHHCCCCEEEEEEEEEEEEEEEECCCCCCCHHHEEEECCCCE
NFRLTAESMMNAFFIPQLGSMVYTMAGMQTRLHLIADTPGVYLGQSAAYSGAGFSDMHFK
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCCCCCCCCCCCCCHHH
TLATSREAFDAWVRSAKASANTLDFKTYRGLERPSNRDAVTLFSAVAPKLFDRVVDKYML
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ANGQVCRADGPESLQAFQPIPSASIGRVEQ
CCCCEEECCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]