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The map label for this gene is namA [H]

Identifier: 17546545

GI number: 17546545

Start: 1994866

End: 1997184

Strand: Reverse

Name: namA [H]

Synonym: RSc1826

Alternate gene names: 17546545

Gene position: 1997184-1994866 (Counterclockwise)

Preceding gene: 17546546

Following gene: 17546544

Centisome position: 53.74

GC content: 70.16

Gene sequence:

>2319_bases
GTGAAAATCGTCTGCCTCGGCGGCGGCCCCGCCGGCCTCTATTTCGGGCTGCTGATGAAGCTGCAGGACCCGTCCAACGA
CGTCGTGGTCATCGAGCGCAACCGCCCCTATGACACCTTCGGCTGGGGCGTCGTGTTCTCCGATGCCACCATGGGCAATC
TGCGGGAGGCCGACCCCGTTTCCGGCGCGACGATCGGCGACGCCTTCAACCGCTGGGACGACGTCGAGGTGCACTTCAAG
GGCGAAGCGGTGCGCAGCGGCGGCCACGGCTTCATCGGGATCGGCCGCAAGAAGCTGCTCAACATCCTCCAGGCCCGCTG
CGAGGAAGTGGGCGTCCAGCTCGTGTTCGAGCAGTATGTCGAAGACGATCAGGCAATCGCCCGCAAATACGGCGCCGACC
TGGTGCTGGCCTCCGACGGCCTCAACAGCCTGGTGCGCAAGCGCTACGCCGAGACCTTCCGCCCGGACATCGACACGCGC
AAGTGCCGCTTCGTGTGGCTCGGCACGAAGAAGGTGTTCGACGCCTTCAACTTCATCTTCGTGCCCACCGAGCATGGCTG
GTTCCAGGCGCACGCCTACCGCTTCGAGGACGGCACCTCCACGTTCATCGTCGAGACGCCGGAAGCGACGTGGAAAGCGG
CCGGCATCGACCAGATGTCGCAGGAAGAAGGCATCGCCTACTGCGAAAAACTTTTCGCCCCCTACCTGGACGGCCACCCG
CTCATCAGCAACGCCTCGCACCTGCGCGGCTCCGCGATCTGGATCCAGTTCCCGCGCGTGATCTGCGAGCGCTGGGTGCA
CTGGAACGAGATCGACGGCAAGCACGTGCCGGTGGTGCTGATGGGCGATGCGGCCCACACCGCGCACTTCTCGATCGGCT
CGGGGACCAAGCTCGCGCTGGAAGACGCCATCGAACTGGCGCGCACGCTCAAGAACGTCGATGGCCCGCTCGAAGCCGCG
CTCCAGCACTATGAGGCGGTCCGCTCGGTGGAAGTCCTGAAGATCCAGAACGCCGCGCGCAACTCGACCGAGTGGTTCGA
GAACGTGGCCCGCTACGCCGGCCTGGCGCCCGAGCAGTTCGCCTATTCGCTGCTGACGCGCTCGCAGCGCATCTCGCACG
AGAACCTGCGCCTGCGCGACCCGAAGTGGCTCGAAGACTACGAGCGCTGGCTGGCGCAGCGCGCCGGCGTGCCGGCCGCC
GACGGCGGGCGCCCCTGCCCGCCCCTGCTGACGCCATACACCGTGCGCGGCATCACCCTGAAAAACCGCGTGGTGGTGTC
GCCCACGCTGCTGTATTCGAGCCAGGACGGCGTGCCGGGGGCCTTCCACCTCGTGCACCTGGGCAGCCGGGCGCTGGGCG
GCGCCGGCCTGCTGCTGACGGAGATGACGGCAGTGGCCCCCGAGGCGCGCATGACGCCGGGATGCCCGGGGCTCTGGAAC
GACGAACAGGCCGCCGCCTGGAAGCGCGTCACCGACTTCGTGCACGGGCACGGCGACACGCGCATCGGCGTGCAGCTCGG
CCACGCGGGGCGCCGCGGCTCGACCCGGGTCGGCTGGGACACGCCCGATCAGCCGCTGGCCGAGGGCAACTGGCCGCTCG
TCTCCGCCAGCGCCTTGCCCTATCTGCCTGGCCGCTCCCAGCTGCCGCGCGAGGCCAGCCTGGACGATCTGGCGCGCATC
CGCGAACAGTTTGTCGAGGCCACGCGCCGCGCCGCGGCCGCCGGCTTCGACTGGCTGGAGCTGCAGGCCGGCCACGGCTT
CCTGCTGTCGAGCTTCATTTCGCCGCTGACCAACCAGCGCACCGACGCCTACGGCGGCGCGCTGGAGAACCGGCTGCGCT
TCCCGCTGGAGGTGCTGGCCGCCGTGCGCGCGGCCTGGCCGGCGCACCTGCCGATCTCGGTGCGCATCTCGTGCACCGAC
TGGGCGCCGGGCGGCACCACGGTCGACGAGGCGGTCGAGATCGCCCGGCGCCTGCACCTGGGCGGCGCGGACCTGGTGGA
CGTCTCGTCCGGCGAGGTCACGCCCGACCAGAAGCCGGTCTACGGCCGCCTGTACCAGACGCCGTTCGCCGACCGCATCC
GCAACGAAGCCCGCGTGCCGACGATCGCGGTGGGCGCCATCAGCGACGCCGACCAGGTCAACGGCATCGTCGCCTCGGGC
CGCGCCGACCTGTGCGCCCTCTCGCGAGCGCACCTGGCGGACGCGGCCTGGGTGCTGCGGGAAAGCGCCCGGCTGGGCTG
GCACGACGTCGAATGGCCGCCCGCCTACCGGTTCGGCAAGGAACCGCTCGAACGCAGCTTTGCCCGCGGCCGCGCGTGA

Upstream 100 bases:

>100_bases
TGGTGTCGACCTCGCTGACGACGCACCGCGCCATCGATATCCCGCAGGCCCTGCGGCAAGCCCTGACCGCGGCCCCCCTC
AACGCAACAAGGAGCGCATC

Downstream 100 bases:

>100_bases
TGCCGGCATTCGCCTGAACCAGACCAAGGAGATCCACGATGACAACAACCGCGTACGACGCCTATCGGGAAAGCATTGCC
GGCCGTGCCGACGTGGCGGA

Product: salicylyl-CoA 5-hydroxylase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MKIVCLGGGPAGLYFGLLMKLQDPSNDVVVIERNRPYDTFGWGVVFSDATMGNLREADPVSGATIGDAFNRWDDVEVHFK
GEAVRSGGHGFIGIGRKKLLNILQARCEEVGVQLVFEQYVEDDQAIARKYGADLVLASDGLNSLVRKRYAETFRPDIDTR
KCRFVWLGTKKVFDAFNFIFVPTEHGWFQAHAYRFEDGTSTFIVETPEATWKAAGIDQMSQEEGIAYCEKLFAPYLDGHP
LISNASHLRGSAIWIQFPRVICERWVHWNEIDGKHVPVVLMGDAAHTAHFSIGSGTKLALEDAIELARTLKNVDGPLEAA
LQHYEAVRSVEVLKIQNAARNSTEWFENVARYAGLAPEQFAYSLLTRSQRISHENLRLRDPKWLEDYERWLAQRAGVPAA
DGGRPCPPLLTPYTVRGITLKNRVVVSPTLLYSSQDGVPGAFHLVHLGSRALGGAGLLLTEMTAVAPEARMTPGCPGLWN
DEQAAAWKRVTDFVHGHGDTRIGVQLGHAGRRGSTRVGWDTPDQPLAEGNWPLVSASALPYLPGRSQLPREASLDDLARI
REQFVEATRRAAAAGFDWLELQAGHGFLLSSFISPLTNQRTDAYGGALENRLRFPLEVLAAVRAAWPAHLPISVRISCTD
WAPGGTTVDEAVEIARRLHLGGADLVDVSSGEVTPDQKPVYGRLYQTPFADRIRNEARVPTIAVGAISDADQVNGIVASG
RADLCALSRAHLADAAWVLRESARLGWHDVEWPPAYRFGKEPLERSFARGRA

Sequences:

>Translated_772_residues
MKIVCLGGGPAGLYFGLLMKLQDPSNDVVVIERNRPYDTFGWGVVFSDATMGNLREADPVSGATIGDAFNRWDDVEVHFK
GEAVRSGGHGFIGIGRKKLLNILQARCEEVGVQLVFEQYVEDDQAIARKYGADLVLASDGLNSLVRKRYAETFRPDIDTR
KCRFVWLGTKKVFDAFNFIFVPTEHGWFQAHAYRFEDGTSTFIVETPEATWKAAGIDQMSQEEGIAYCEKLFAPYLDGHP
LISNASHLRGSAIWIQFPRVICERWVHWNEIDGKHVPVVLMGDAAHTAHFSIGSGTKLALEDAIELARTLKNVDGPLEAA
LQHYEAVRSVEVLKIQNAARNSTEWFENVARYAGLAPEQFAYSLLTRSQRISHENLRLRDPKWLEDYERWLAQRAGVPAA
DGGRPCPPLLTPYTVRGITLKNRVVVSPTLLYSSQDGVPGAFHLVHLGSRALGGAGLLLTEMTAVAPEARMTPGCPGLWN
DEQAAAWKRVTDFVHGHGDTRIGVQLGHAGRRGSTRVGWDTPDQPLAEGNWPLVSASALPYLPGRSQLPREASLDDLARI
REQFVEATRRAAAAGFDWLELQAGHGFLLSSFISPLTNQRTDAYGGALENRLRFPLEVLAAVRAAWPAHLPISVRISCTD
WAPGGTTVDEAVEIARRLHLGGADLVDVSSGEVTPDQKPVYGRLYQTPFADRIRNEARVPTIAVGAISDADQVNGIVASG
RADLCALSRAHLADAAWVLRESARLGWHDVEWPPAYRFGKEPLERSFARGRA
>Mature_772_residues
MKIVCLGGGPAGLYFGLLMKLQDPSNDVVVIERNRPYDTFGWGVVFSDATMGNLREADPVSGATIGDAFNRWDDVEVHFK
GEAVRSGGHGFIGIGRKKLLNILQARCEEVGVQLVFEQYVEDDQAIARKYGADLVLASDGLNSLVRKRYAETFRPDIDTR
KCRFVWLGTKKVFDAFNFIFVPTEHGWFQAHAYRFEDGTSTFIVETPEATWKAAGIDQMSQEEGIAYCEKLFAPYLDGHP
LISNASHLRGSAIWIQFPRVICERWVHWNEIDGKHVPVVLMGDAAHTAHFSIGSGTKLALEDAIELARTLKNVDGPLEAA
LQHYEAVRSVEVLKIQNAARNSTEWFENVARYAGLAPEQFAYSLLTRSQRISHENLRLRDPKWLEDYERWLAQRAGVPAA
DGGRPCPPLLTPYTVRGITLKNRVVVSPTLLYSSQDGVPGAFHLVHLGSRALGGAGLLLTEMTAVAPEARMTPGCPGLWN
DEQAAAWKRVTDFVHGHGDTRIGVQLGHAGRRGSTRVGWDTPDQPLAEGNWPLVSASALPYLPGRSQLPREASLDDLARI
REQFVEATRRAAAAGFDWLELQAGHGFLLSSFISPLTNQRTDAYGGALENRLRFPLEVLAAVRAAWPAHLPISVRISCTD
WAPGGTTVDEAVEIARRLHLGGADLVDVSSGEVTPDQKPVYGRLYQTPFADRIRNEARVPTIAVGAISDADQVNGIVASG
RADLCALSRAHLADAAWVLRESARLGWHDVEWPPAYRFGKEPLERSFARGRA

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=344, Percent_Identity=31.9767441860465, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1789463, Length=341, Percent_Identity=28.1524926686217, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17565138, Length=237, Percent_Identity=29.535864978903, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=226, Percent_Identity=29.646017699115, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559802, Length=173, Percent_Identity=34.1040462427746, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI72001454, Length=228, Percent_Identity=29.3859649122807, Blast_Score=93, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=226, Percent_Identity=29.646017699115, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540738, Length=173, Percent_Identity=31.2138728323699, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17566914, Length=238, Percent_Identity=25.2100840336134, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=30.6666666666667, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=225, Percent_Identity=28.4444444444444, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 85071; Mature: 85071

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVCLGGGPAGLYFGLLMKLQDPSNDVVVIERNRPYDTFGWGVVFSDATMGNLREADPV
CEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCC
SGATIGDAFNRWDDVEVHFKGEAVRSGGHGFIGIGRKKLLNILQARCEEVGVQLVFEQYV
CCCCHHHHHCCCCCEEEEEECCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
EDDQAIARKYGADLVLASDGLNSLVRKRYAETFRPDIDTRKCRFVWLGTKKVFDAFNFIF
CHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHCCCCEEE
VPTEHGWFQAHAYRFEDGTSTFIVETPEATWKAAGIDQMSQEEGIAYCEKLFAPYLDGHP
EECCCCCEEEEEEEECCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
LISNASHLRGSAIWIQFPRVICERWVHWNEIDGKHVPVVLMGDAAHTAHFSIGSGTKLAL
CCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHH
EDAIELARTLKNVDGPLEAALQHYEAVRSVEVLKIQNAARNSTEWFENVARYAGLAPEQF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEHHHCCCHHHHHHHHHHHCCCCHHHH
AYSLLTRSQRISHENLRLRDPKWLEDYERWLAQRAGVPAADGGRPCPPLLTPYTVRGITL
HHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEE
KNRVVVSPTLLYSSQDGVPGAFHLVHLGSRALGGAGLLLTEMTAVAPEARMTPGCPGLWN
CCEEEEEEEEEECCCCCCCHHHHEEECCCHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
DEQAAAWKRVTDFVHGHGDTRIGVQLGHAGRRGSTRVGWDTPDQPLAEGNWPLVSASALP
CHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
YLPGRSQLPREASLDDLARIREQFVEATRRAAAAGFDWLELQAGHGFLLSSFISPLTNQR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCC
TDAYGGALENRLRFPLEVLAAVRAAWPAHLPISVRISCTDWAPGGTTVDEAVEIARRLHL
CCHHCCHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHC
GGADLVDVSSGEVTPDQKPVYGRLYQTPFADRIRNEARVPTIAVGAISDADQVNGIVASG
CCCCEEECCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCCEEEEECCCCHHHHCCEEECC
RADLCALSRAHLADAAWVLRESARLGWHDVEWPPAYRFGKEPLERSFARGRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHCCCC
>Mature Secondary Structure
MKIVCLGGGPAGLYFGLLMKLQDPSNDVVVIERNRPYDTFGWGVVFSDATMGNLREADPV
CEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCC
SGATIGDAFNRWDDVEVHFKGEAVRSGGHGFIGIGRKKLLNILQARCEEVGVQLVFEQYV
CCCCHHHHHCCCCCEEEEEECCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
EDDQAIARKYGADLVLASDGLNSLVRKRYAETFRPDIDTRKCRFVWLGTKKVFDAFNFIF
CHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHCCCCEEE
VPTEHGWFQAHAYRFEDGTSTFIVETPEATWKAAGIDQMSQEEGIAYCEKLFAPYLDGHP
EECCCCCEEEEEEEECCCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
LISNASHLRGSAIWIQFPRVICERWVHWNEIDGKHVPVVLMGDAAHTAHFSIGSGTKLAL
CCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHH
EDAIELARTLKNVDGPLEAALQHYEAVRSVEVLKIQNAARNSTEWFENVARYAGLAPEQF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEHHHCCCHHHHHHHHHHHCCCCHHHH
AYSLLTRSQRISHENLRLRDPKWLEDYERWLAQRAGVPAADGGRPCPPLLTPYTVRGITL
HHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEE
KNRVVVSPTLLYSSQDGVPGAFHLVHLGSRALGGAGLLLTEMTAVAPEARMTPGCPGLWN
CCEEEEEEEEEECCCCCCCHHHHEEECCCHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
DEQAAAWKRVTDFVHGHGDTRIGVQLGHAGRRGSTRVGWDTPDQPLAEGNWPLVSASALP
CHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
YLPGRSQLPREASLDDLARIREQFVEATRRAAAAGFDWLELQAGHGFLLSSFISPLTNQR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCC
TDAYGGALENRLRFPLEVLAAVRAAWPAHLPISVRISCTDWAPGGTTVDEAVEIARRLHL
CCHHCCHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHC
GGADLVDVSSGEVTPDQKPVYGRLYQTPFADRIRNEARVPTIAVGAISDADQVNGIVASG
CCCCEEECCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCCEEEEECCCCHHHHCCEEECC
RADLCALSRAHLADAAWVLRESARLGWHDVEWPPAYRFGKEPLERSFARGRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA