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The map label for this gene is coxS [H]

Identifier: 17546188

GI number: 17546188

Start: 1573110

End: 1573637

Strand: Reverse

Name: coxS [H]

Synonym: RSc1469

Alternate gene names: 17546188

Gene position: 1573637-1573110 (Counterclockwise)

Preceding gene: 17546189

Following gene: 17546187

Centisome position: 42.34

GC content: 69.7

Gene sequence:

>528_bases
ATGGCGATCAGCCTCAGCCTGTCGGTCAACGGCGCGCCCGTCACCGTCAGCGTCGAACCCCATACCCTGCTGGTCGAGCT
GCTGCGCGAGCACCTGAGGCTCACCGGTACGCATGTCGGCTGCGATACCGCGCAATGCGGCGCCTGCACCGTCCACATGA
ACGGCCGCGCGGTGAAGTCGTGCAATATCCTGGCCGTGCAGGCCGACGGCGCGGACGTCACCACCATCGAAGGCCTGGCC
AGGAACGGCAAGCTGCACCCGATGCAGGAAGCCTTCCGCGAATGCCACGGCCTGCAATGCGGCTTCTGCACGCCGGGCAT
GGTGATGGCGGCGACCGCGCTGGTCGCGCAGTACCCCCATCCCGACGAGCGCCAGGTGCGCGAGCAGCTGGACGGCAACC
TGTGCCGCTGCACGGGCTACCACAACATCGTGCGCGCCGTGCTGCAAGGCGCCGAGGCCATGGCGGCTGCCGAAGGCGAA
GACGCCTCGCTGCAGAGCCTGGCCGCCGCGCGCGCCCATGCCGCCTGA

Upstream 100 bases:

>100_bases
TGGTGTGCTTTACTGAGTAGAGCCGCGACCACCCACACAGACCTCGCGCGCATCTTCGCTGCGACGCAGGCATCCGGCGC
CCATCCCCAAGGAGACTCCC

Downstream 100 bases:

>100_bases
CGCGAGGAGACCGCCATGAACGCTCCCGCAGAACCCAACCGCCACCTGATCGGCGCGGCCGTCAAGCGCAAGGAGGACTA
CCGCTTCCTGACGGGCGCGG

Product: dehydrogenase oxidoreductase

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MAISLSLSVNGAPVTVSVEPHTLLVELLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKSCNILAVQADGADVTTIEGLA
RNGKLHPMQEAFRECHGLQCGFCTPGMVMAATALVAQYPHPDERQVREQLDGNLCRCTGYHNIVRAVLQGAEAMAAAEGE
DASLQSLAAARAHAA

Sequences:

>Translated_175_residues
MAISLSLSVNGAPVTVSVEPHTLLVELLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKSCNILAVQADGADVTTIEGLA
RNGKLHPMQEAFRECHGLQCGFCTPGMVMAATALVAQYPHPDERQVREQLDGNLCRCTGYHNIVRAVLQGAEAMAAAEGE
DASLQSLAAARAHAA
>Mature_174_residues
AISLSLSVNGAPVTVSVEPHTLLVELLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKSCNILAVQADGADVTTIEGLAR
NGKLHPMQEAFRECHGLQCGFCTPGMVMAATALVAQYPHPDERQVREQLDGNLCRCTGYHNIVRAVLQGAEAMAAAEGED
ASLQSLAAARAHAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=157, Percent_Identity=40.7643312101911, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI91823271, Length=166, Percent_Identity=38.5542168674699, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=41.4634146341463, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789232, Length=151, Percent_Identity=45.0331125827815, Blast_Score=128, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17540638, Length=157, Percent_Identity=43.9490445859873, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=38.8157894736842, Blast_Score=116, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=36.8421052631579, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI17737937, Length=168, Percent_Identity=42.2619047619048, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=37.5, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=37.5, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=34.4155844155844, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=36.1290322580645, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24647193, Length=156, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 18411; Mature: 18280

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISLSLSVNGAPVTVSVEPHTLLVELLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKS
CEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECC
CNILAVQADGADVTTIEGLARNGKLHPMQEAFRECHGLQCGFCTPGMVMAATALVAQYPH
CEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
PDERQVREQLDGNLCRCTGYHNIVRAVLQGAEAMAAAEGEDASLQSLAAARAHAA
CCHHHHHHHHCCCEEEECCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AISLSLSVNGAPVTVSVEPHTLLVELLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKS
EEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECC
CNILAVQADGADVTTIEGLARNGKLHPMQEAFRECHGLQCGFCTPGMVMAATALVAQYPH
CEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
PDERQVREQLDGNLCRCTGYHNIVRAVLQGAEAMAAAEGEDASLQSLAAARAHAA
CCHHHHHHHHCCCEEEECCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]