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The map label for this gene is cutL [H]

Identifier: 17546187

GI number: 17546187

Start: 1570710

End: 1573094

Strand: Reverse

Name: cutL [H]

Synonym: RSc1468

Alternate gene names: 17546187

Gene position: 1573094-1570710 (Counterclockwise)

Preceding gene: 17546188

Following gene: 17546186

Centisome position: 42.33

GC content: 69.31

Gene sequence:

>2385_bases
ATGAACGCTCCCGCAGAACCCAACCGCCACCTGATCGGCGCGGCCGTCAAGCGCAAGGAGGACTACCGCTTCCTGACGGG
CGCGGGCCAGTACACCGACGACGTGGTGCAGGCACACCAGTCCTACGCCGTGTTCCTGCGCTCGCCGTATGCGCACGCGC
GCATTGTCCGCATCGATGCCGAAGCCGCCCGCAAGCAGCGCGGCGTGCTCGCCGTGCTCACGGGCGAGGACCTTGCCACC
GACAAGGTCAACGGCTTGCCGTGCGGCTGGCTGATCCACAGCCTCGACGGCTCGCCGATGAAGGAGCCGCCCCACCCCGT
GCTCGCGCAGGGCAAGGTGCGCCACGTGGGCGACCAGGTCGCGCTGGTGGTGGCCGAGTCGGTGAAGATCGCCAAGGATG
CCGTCGAGCTGATCGACGTGGAATATGAAGAGCTGCCCGCCGTGGTCGACCCTGCCGCGGCAAGCACCGCCGGCACCGCG
GTCCACGACGGCGTGCCCGACAACACCTGCTACACCTGGGGCCACGGCGACAAGGCTGCCACCGACGCCGCCTTCGCCCG
CGCCGCGCATGTCACCCGGCTCGACATCGTCAACAACCGGCTGATCCCGAACGCCATCGAGCCGCGTGCCGTGAACGCGA
GCTACTCGCGGCAGGACGACAGCTACACGCTCTATGTCGCCAACCAGAACCCGCACGTCGAGCGGCTGCTGATGTCGGCG
TTCGTGCTGGGGCTGTCCGAGGCCAAGGTGCGCGTGATCGCGCCCGACGTGGGCGGCGGCTTCGGCTCGAAGATCTTCCT
GTACCCGGAAGACGTGGCGCTGACCTGGGCATCGAAGAAGGTCGGCCGGCCGATCAAGTGGACGGCCGAGCGTTCCGAGT
CCTTCCTGACCGACGCGCATGGCCGCGATCACGTCACGCACGCAGAACTGGCGCTCGACGCGCAAGGCAACTTCCTCGGC
ATGCGCGTGCACACCATCGCCAACATGGGTGCGTACCTGTCGACGTTCGCCAGCAGCGTGCCGACCATCCTGTATGCCAC
GCTGCTCGCCGGGCAGTACCGGACGCCCGCCATCTACGCGGAAGTCAAGGCGGTGTTCACCAACACCGCGCCGGTCGATG
CCTATCGGGGTGCCGGGCGGCCGGAAGCCACCTATGTGGTCGAGCGGCTGGTCGAGACCGCGGCGCGCGAGCTGCAGATC
GACCCGGCCGAACTGCGCCGCCGCAACTTCATCCGCAGCTTCCCGTATGCCACGCCGGTCGGCCTGACGTATGACACGGG
CGACTACGAACCCTGCCTGGACCGCGCCATCGAACTGGCCGACGTGCCGGGCTTGCGCGCCCGCCGCGACGCCTCGCGCG
CCAAGGGCCGGCTGCGCGGCATGGGCTACTCCTGCTACATCGAGGCGTGCGGGCTGGCGCCGTCCAACATCGCCGGGGCG
CTGGGCGCGCGCGCGGGCCTGTTCGAGGTGGGCGAGATCCGCGTGCACCCGACCGGCTCCGTCACCGTGTTCACCGGCTC
GCACAGCCACGGACAAGGGCACGAGACGACCTTCGCGCAGGTGGTGGCCGATCGCCTGGGCGTGCCGATCGAGAACGTCG
AGATCGTGCACGGCGATACCGGGCGCATCCCCTTCGGCATGGGCACGTACGGCTCGCGCTCGATCGCGGTGGGCGGCTCG
GCCGTCATGAAGGCGCTCGACAAGATCGAGGCCAAGGCCAAGAAGATCGCCGCGCACCTGCTGGAAGCCTCCGCCGAGGA
CATCGAGTTCAAGGACGGCGTCTTCCGCGTGGCCGGCACCGACCGCACCAAGACCTTCGGCGAGGTCGCGCTCACGGCCT
ATGTGCCGCACAACTACCCCCTCGACAAGCTCGAGCCGGGCCTGAACGAAAACGCCTTCTACGACCCGGCCAACTTCACC
TACCCGGCCGGCGCCTACATTTGCGAGGTGGAGGTCGACCCCGAGACCGGCGAGGTGCGCATCGACCGCTTCGTGGCGGT
GGACGACTTCGGCAACATCATCAACCCGATGATCGTCGAGGGCCAGGTGCACGGCGGACTCGGCCAGGGCATCGGCCAGG
CGCTGCTGGAGGGCTGCGTGTACGACGACAGCGGCCAGCTGCTGACCGGCTCCTACATGGACTACGCCATGCCGCGCGCC
GACGACCTGCCGAGCTTCACCGTGGAGACCGCCAAGGGCACGCCCTGCACGCACAACCCGCTGGGCGTGAAGGGCTGCGG
CGAGGCCGGCGCGATCGGCTCGCCGCCGGCGCTGATCAACGCCATCGTCGATGCCCTGGCGCCGCTGGGCGTGAAGGACA
TCCAGATGCCGGCCACGCCCCACCGCGTCTGGCGGGCCATCCAATCCGCGCGGGCGAATGCCTGA

Upstream 100 bases:

>100_bases
GCAAGGCGCCGAGGCCATGGCGGCTGCCGAAGGCGAAGACGCCTCGCTGCAGAGCCTGGCCGCCGCGCGCGCCCATGCCG
CCTGACGCGAGGAGACCGCC

Downstream 100 bases:

>100_bases
CCTGACCAGGAGCGCGCCATGTATGCCTTCGAGTACCACAAAGCCACCGACGCCCAGACCGCCGTCACCGCGCTGAAGAT
GCATCCGGACGGCAAGTACC

Product: oxidoreductase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MNAPAEPNRHLIGAAVKRKEDYRFLTGAGQYTDDVVQAHQSYAVFLRSPYAHARIVRIDAEAARKQRGVLAVLTGEDLAT
DKVNGLPCGWLIHSLDGSPMKEPPHPVLAQGKVRHVGDQVALVVAESVKIAKDAVELIDVEYEELPAVVDPAAASTAGTA
VHDGVPDNTCYTWGHGDKAATDAAFARAAHVTRLDIVNNRLIPNAIEPRAVNASYSRQDDSYTLYVANQNPHVERLLMSA
FVLGLSEAKVRVIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTHAELALDAQGNFLG
MRVHTIANMGAYLSTFASSVPTILYATLLAGQYRTPAIYAEVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAARELQI
DPAELRRRNFIRSFPYATPVGLTYDTGDYEPCLDRAIELADVPGLRARRDASRAKGRLRGMGYSCYIEACGLAPSNIAGA
LGARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQVVADRLGVPIENVEIVHGDTGRIPFGMGTYGSRSIAVGGS
AVMKALDKIEAKAKKIAAHLLEASAEDIEFKDGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPANFT
YPAGAYICEVEVDPETGEVRIDRFVAVDDFGNIINPMIVEGQVHGGLGQGIGQALLEGCVYDDSGQLLTGSYMDYAMPRA
DDLPSFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPALINAIVDALAPLGVKDIQMPATPHRVWRAIQSARANA

Sequences:

>Translated_794_residues
MNAPAEPNRHLIGAAVKRKEDYRFLTGAGQYTDDVVQAHQSYAVFLRSPYAHARIVRIDAEAARKQRGVLAVLTGEDLAT
DKVNGLPCGWLIHSLDGSPMKEPPHPVLAQGKVRHVGDQVALVVAESVKIAKDAVELIDVEYEELPAVVDPAAASTAGTA
VHDGVPDNTCYTWGHGDKAATDAAFARAAHVTRLDIVNNRLIPNAIEPRAVNASYSRQDDSYTLYVANQNPHVERLLMSA
FVLGLSEAKVRVIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTHAELALDAQGNFLG
MRVHTIANMGAYLSTFASSVPTILYATLLAGQYRTPAIYAEVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAARELQI
DPAELRRRNFIRSFPYATPVGLTYDTGDYEPCLDRAIELADVPGLRARRDASRAKGRLRGMGYSCYIEACGLAPSNIAGA
LGARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQVVADRLGVPIENVEIVHGDTGRIPFGMGTYGSRSIAVGGS
AVMKALDKIEAKAKKIAAHLLEASAEDIEFKDGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPANFT
YPAGAYICEVEVDPETGEVRIDRFVAVDDFGNIINPMIVEGQVHGGLGQGIGQALLEGCVYDDSGQLLTGSYMDYAMPRA
DDLPSFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPALINAIVDALAPLGVKDIQMPATPHRVWRAIQSARANA
>Mature_794_residues
MNAPAEPNRHLIGAAVKRKEDYRFLTGAGQYTDDVVQAHQSYAVFLRSPYAHARIVRIDAEAARKQRGVLAVLTGEDLAT
DKVNGLPCGWLIHSLDGSPMKEPPHPVLAQGKVRHVGDQVALVVAESVKIAKDAVELIDVEYEELPAVVDPAAASTAGTA
VHDGVPDNTCYTWGHGDKAATDAAFARAAHVTRLDIVNNRLIPNAIEPRAVNASYSRQDDSYTLYVANQNPHVERLLMSA
FVLGLSEAKVRVIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTHAELALDAQGNFLG
MRVHTIANMGAYLSTFASSVPTILYATLLAGQYRTPAIYAEVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAARELQI
DPAELRRRNFIRSFPYATPVGLTYDTGDYEPCLDRAIELADVPGLRARRDASRAKGRLRGMGYSCYIEACGLAPSNIAGA
LGARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQVVADRLGVPIENVEIVHGDTGRIPFGMGTYGSRSIAVGGS
AVMKALDKIEAKAKKIAAHLLEASAEDIEFKDGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPANFT
YPAGAYICEVEVDPETGEVRIDRFVAVDDFGNIINPMIVEGQVHGGLGQGIGQALLEGCVYDDSGQLLTGSYMDYAMPRA
DDLPSFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPALINAIVDALAPLGVKDIQMPATPHRVWRAIQSARANA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=801, Percent_Identity=23.8451935081149, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI91823271, Length=789, Percent_Identity=23.3206590621039, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789230, Length=780, Percent_Identity=29.4871794871795, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI1789246, Length=828, Percent_Identity=27.2946859903382, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI1786478, Length=735, Percent_Identity=26.8027210884354, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17540638, Length=830, Percent_Identity=25.1807228915663, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17539860, Length=817, Percent_Identity=23.6230110159119, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17737937, Length=797, Percent_Identity=25.7214554579674, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24647193, Length=812, Percent_Identity=23.0295566502463, Blast_Score=102, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85128; Mature: 85128

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPAEPNRHLIGAAVKRKEDYRFLTGAGQYTDDVVQAHQSYAVFLRSPYAHARIVRIDA
CCCCCCCCCEEEHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEEEEECCCCCEEEEEEEH
EAARKQRGVLAVLTGEDLATDKVNGLPCGWLIHSLDGSPMKEPPHPVLAQGKVRHVGDQV
HHHHHHCCEEEEEECCCCCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCHHHCCCEE
ALVVAESVKIAKDAVELIDVEYEELPAVVDPAAASTAGTAVHDGVPDNTCYTWGHGDKAA
EEEEHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHCCCCCCCCEEECCCCCCHH
TDAAFARAAHVTRLDIVNNRLIPNAIEPRAVNASYSRQDDSYTLYVANQNPHVERLLMSA
HHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
FVLGLSEAKVRVIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAH
HHHCCCCCEEEEEECCCCCCCCCEEEEEECCEEEEECHHHCCCCEEEEHHHHHHHHHCCC
GRDHVTHAELALDAQGNFLGMRVHTIANMGAYLSTFASSVPTILYATLLAGQYRTPAIYA
CCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHE
EVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAARELQIDPAELRRRNFIRSFPYATPV
EEEHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
GLTYDTGDYEPCLDRAIELADVPGLRARRDASRAKGRLRGMGYSCYIEACGLAPSNIAGA
CEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
LGARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQVVADRLGVPIENVEIVHGDT
HHCCCCCEEECEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
GRIPFGMGTYGSRSIAVGGSAVMKALDKIEAKAKKIAAHLLEASAEDIEFKDGVFRVAGT
CCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECC
DRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPANFTYPAGAYICEVEVDPETGEVR
CCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCEE
IDRFVAVDDFGNIINPMIVEGQVHGGLGQGIGQALLEGCVYDDSGQLLTGSYMDYAMPRA
EEEEEEECHHCHHCCCEEEEEEECCCHHHHHHHHHHHCCEECCCCCEEECCHHHHCCCCC
DDLPSFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPALINAIVDALAPLGVKDIQMPATP
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
HRVWRAIQSARANA
HHHHHHHHHHCCCC
>Mature Secondary Structure
MNAPAEPNRHLIGAAVKRKEDYRFLTGAGQYTDDVVQAHQSYAVFLRSPYAHARIVRIDA
CCCCCCCCCEEEHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEEEEECCCCCEEEEEEEH
EAARKQRGVLAVLTGEDLATDKVNGLPCGWLIHSLDGSPMKEPPHPVLAQGKVRHVGDQV
HHHHHHCCEEEEEECCCCCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCHHHCCCEE
ALVVAESVKIAKDAVELIDVEYEELPAVVDPAAASTAGTAVHDGVPDNTCYTWGHGDKAA
EEEEHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHCCCCCCCCEEECCCCCCHH
TDAAFARAAHVTRLDIVNNRLIPNAIEPRAVNASYSRQDDSYTLYVANQNPHVERLLMSA
HHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
FVLGLSEAKVRVIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAH
HHHCCCCCEEEEEECCCCCCCCCEEEEEECCEEEEECHHHCCCCEEEEHHHHHHHHHCCC
GRDHVTHAELALDAQGNFLGMRVHTIANMGAYLSTFASSVPTILYATLLAGQYRTPAIYA
CCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHE
EVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAARELQIDPAELRRRNFIRSFPYATPV
EEEHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
GLTYDTGDYEPCLDRAIELADVPGLRARRDASRAKGRLRGMGYSCYIEACGLAPSNIAGA
CEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
LGARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQVVADRLGVPIENVEIVHGDT
HHCCCCCEEECEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
GRIPFGMGTYGSRSIAVGGSAVMKALDKIEAKAKKIAAHLLEASAEDIEFKDGVFRVAGT
CCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECC
DRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPANFTYPAGAYICEVEVDPETGEVR
CCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCEE
IDRFVAVDDFGNIINPMIVEGQVHGGLGQGIGQALLEGCVYDDSGQLLTGSYMDYAMPRA
EEEEEEECHHCHHCCCEEEEEEECCCHHHHHHHHHHHCCEECCCCCEEECCHHHHCCCCC
DDLPSFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPALINAIVDALAPLGVKDIQMPATP
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
HRVWRAIQSARANA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]