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The map label for this gene is ybiT [H]

Identifier: 17546172

GI number: 17546172

Start: 1554140

End: 1555762

Strand: Direct

Name: ybiT [H]

Synonym: RSc1453

Alternate gene names: 17546172

Gene position: 1554140-1555762 (Clockwise)

Preceding gene: 17546171

Following gene: 17546173

Centisome position: 41.82

GC content: 64.26

Gene sequence:

>1623_bases
GTGCTTTCCACCGCCAACATCACCATGCAGTTCGGGCCCAAGCCCTTGTTCGAGAACATCTCGGTCAAGTTCGGCGAGGG
CAATCGCTATGGCCTGATCGGCGCCAACGGCTGCGGCAAGTCGACCTTCATGAAGATCCTGGGCAGCGATCTGGAGCCGA
GCGCAGGCAATGTGATGCTGGAGCCGGGCGTGCGCCTGGGCAAGCTGCGCCAGGACCAGTTCGCCTACGAAGACATGCGC
GTGCTCGACGTGGTGATGATGGGCCACACCGAGATGTGGGCCGCCGCGCAGGAGCGCGACGCCATCTACGCCAACCCGGA
AGCGACCGACGACGACTACATGAAGGCCGCCGACCTGGAGGCCAAGTACGCCGAATACGACGGCTACACCGCTGAGGCCC
GCGCGGGCGAACTGCTGCTCGGCGTCGGTATCCCGATCGATCAGCACAACGGCCCGATGAGCAGCGTCGCCCCCGGCTGG
AAGCTGCGCGTGCTGCTGGCGCAGGCGCTGTTCTCGAATCCGGACGTGCTGCTGCTGGACGAGCCGACCAACAACCTCGA
CATCAACACGATCCGCTGGCTGGAATCGGTGCTCAACGAGCGCAATTCCACCATGATCATCATCTCCCACGATCGCCACT
TCCTGAACTCGGTCTGTACCCACATGGCCGACATGGACTACGGCACGCTCAAGGTCTACCCGGGCAACTACGACGACTAC
ATGGAAGCCTCCATCCAGGCGCGCGAACGCCTGCAGGCCGCCAATGCGCGCGCCAAGGAGCGCATCTCCGACCTGCAGGA
CTTCGTGCGCCGCTTCTCGGCCAACAAGTCCAAGGCGCGCCAGGCCACGTCGCGCCTGAAGATGATCGACAAGATCAAGG
TGGAAGACATCAAGCCGTCGTCGCGCCAGAACCCGTTCATCCGCTTCGAGTTCGAGAAGAAGCTGCACAACCTGGCGGTG
GAAGCCGAGAACGCGCGCAAGACGTACGACCGCAAGATCTTCGACGGCCTGACCATGGCCGTGCGCGCCGGCGAGAAGAT
CGCCATCATCGGCGAGAACGGCGCGGGCAAGACCACGCTGCTGCGCTCGCTGCTCAACCACTCGGTCAAGACCGGTGTGC
AGCGCGGCATCGACGTGGACGGCGGCATCATCAAGTGGGCCGAGCACGCCAACGTCGGCTACATGCCGCAGGACACCTAC
GAAGAATTCCCCGAAGACCGCGACCTGATGGACTGGATGAGCCAGTGGACGCAGGCCGGCGACGACGACCAATCGCTGCG
CGGCACGATGGGCCGCCTGCTGTTCTCGGCCGACGACATCAAGAAGAGCGTCAAGGTGCTCTCCGGCGGCGAGAAGGGCC
GCATGATCTGGGGCAAGCTGATGCTGGGCCGCCACAACGTGCTGGCGCTGGACGAGCCGACCAACCACATGGACATGGAG
TCGATCGAGTCGCTGCAGGTCGCGCTGGACAAGTTCGAGGGCACGCTGATCTTCGTCTCGCACGACCGCGAGTTCGTCAG
CGGCCTGGCCACGCGCGTCATCGAAGTGCGGCCGGACGGCACGCTGACCGACTACCTCGGCACGTATGACGAGTATCTGC
AGAGCCAGGGCGTGGAGGTCTGA

Upstream 100 bases:

>100_bases
CCGCGTCACCGGCGGGTGGTAAAATTCCAGGTTTTCCAGATGGTGTCTGGCCTGTCACTGTGCCGGCGCCGCTCACCGCT
TTTTTCATCAGGGTTTCCAC

Downstream 100 bases:

>100_bases
GCGTCGCCATTGCCGATCCGCCAGGAAGGAGGCCGCGTTTACCGCGGCCTTTTTTTTTCGCGCGGGCGCCGGAAGCCAGG
CCTTGGAATCGCGCTACCCG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGSDLEPSAGNVMLEPGVRLGKLRQDQFAYEDMR
VLDVVMMGHTEMWAAAQERDAIYANPEATDDDYMKAADLEAKYAEYDGYTAEARAGELLLGVGIPIDQHNGPMSSVAPGW
KLRVLLAQALFSNPDVLLLDEPTNNLDINTIRWLESVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
MEASIQARERLQAANARAKERISDLQDFVRRFSANKSKARQATSRLKMIDKIKVEDIKPSSRQNPFIRFEFEKKLHNLAV
EAENARKTYDRKIFDGLTMAVRAGEKIAIIGENGAGKTTLLRSLLNHSVKTGVQRGIDVDGGIIKWAEHANVGYMPQDTY
EEFPEDRDLMDWMSQWTQAGDDDQSLRGTMGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
SIESLQVALDKFEGTLIFVSHDREFVSGLATRVIEVRPDGTLTDYLGTYDEYLQSQGVEV

Sequences:

>Translated_540_residues
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGSDLEPSAGNVMLEPGVRLGKLRQDQFAYEDMR
VLDVVMMGHTEMWAAAQERDAIYANPEATDDDYMKAADLEAKYAEYDGYTAEARAGELLLGVGIPIDQHNGPMSSVAPGW
KLRVLLAQALFSNPDVLLLDEPTNNLDINTIRWLESVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
MEASIQARERLQAANARAKERISDLQDFVRRFSANKSKARQATSRLKMIDKIKVEDIKPSSRQNPFIRFEFEKKLHNLAV
EAENARKTYDRKIFDGLTMAVRAGEKIAIIGENGAGKTTLLRSLLNHSVKTGVQRGIDVDGGIIKWAEHANVGYMPQDTY
EEFPEDRDLMDWMSQWTQAGDDDQSLRGTMGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
SIESLQVALDKFEGTLIFVSHDREFVSGLATRVIEVRPDGTLTDYLGTYDEYLQSQGVEV
>Mature_540_residues
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGSDLEPSAGNVMLEPGVRLGKLRQDQFAYEDMR
VLDVVMMGHTEMWAAAQERDAIYANPEATDDDYMKAADLEAKYAEYDGYTAEARAGELLLGVGIPIDQHNGPMSSVAPGW
KLRVLLAQALFSNPDVLLLDEPTNNLDINTIRWLESVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
MEASIQARERLQAANARAKERISDLQDFVRRFSANKSKARQATSRLKMIDKIKVEDIKPSSRQNPFIRFEFEKKLHNLAV
EAENARKTYDRKIFDGLTMAVRAGEKIAIIGENGAGKTTLLRSLLNHSVKTGVQRGIDVDGGIIKWAEHANVGYMPQDTY
EEFPEDRDLMDWMSQWTQAGDDDQSLRGTMGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
SIESLQVALDKFEGTLIFVSHDREFVSGLATRVIEVRPDGTLTDYLGTYDEYLQSQGVEV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=547, Percent_Identity=31.4442413162706, Blast_Score=245, Evalue=7e-65,
Organism=Homo sapiens, GI10947137, Length=543, Percent_Identity=28.9134438305709, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI27881506, Length=543, Percent_Identity=29.4659300184162, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI10947135, Length=553, Percent_Identity=27.124773960217, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI69354671, Length=553, Percent_Identity=27.124773960217, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=65.3703703703704, Blast_Score=744, Evalue=0.0,
Organism=Escherichia coli, GI1789751, Length=538, Percent_Identity=32.5278810408922, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1787182, Length=548, Percent_Identity=30.8394160583942, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI2367384, Length=531, Percent_Identity=28.4369114877589, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=27.0386266094421, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788165, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788761, Length=244, Percent_Identity=24.5901639344262, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=541, Percent_Identity=31.6081330868762, Blast_Score=234, Evalue=9e-62,
Organism=Caenorhabditis elegans, GI17555318, Length=541, Percent_Identity=29.0203327171904, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17559834, Length=511, Percent_Identity=27.5929549902153, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI115533592, Length=211, Percent_Identity=27.4881516587678, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=197, Percent_Identity=26.9035532994924, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=545, Percent_Identity=27.7064220183486, Blast_Score=220, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6321121, Length=544, Percent_Identity=28.3088235294118, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6323278, Length=434, Percent_Identity=24.4239631336406, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324314, Length=437, Percent_Identity=24.9427917620137, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325030, Length=426, Percent_Identity=24.8826291079812, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666836, Length=536, Percent_Identity=29.2910447761194, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24642252, Length=537, Percent_Identity=27.7467411545624, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI18859989, Length=537, Percent_Identity=27.7467411545624, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24641342, Length=556, Percent_Identity=28.7769784172662, Blast_Score=212, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60549; Mature: 60549

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGSDLEPSAGNVML
CCCCCEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
EPGVRLGKLRQDQFAYEDMRVLDVVMMGHTEMWAAAQERDAIYANPEATDDDYMKAADLE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCHHHHHHCCC
AKYAEYDGYTAEARAGELLLGVGIPIDQHNGPMSSVAPGWKLRVLLAQALFSNPDVLLLD
HHHHHCCCEECCCCCCCEEEEECCEECCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDINTIRWLESVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
CCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
MEASIQARERLQAANARAKERISDLQDFVRRFSANKSKARQATSRLKMIDKIKVEDIKPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCC
SRQNPFIRFEFEKKLHNLAVEAENARKTYDRKIFDGLTMAVRAGEKIAIIGENGAGKTTL
CCCCCEEEEEHHHHHHHHHEECHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCHHHH
LRSLLNHSVKTGVQRGIDVDGGIIKWAEHANVGYMPQDTYEEFPEDRDLMDWMSQWTQAG
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCC
DDDQSLRGTMGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
CCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCCCCHH
SIESLQVALDKFEGTLIFVSHDREFVSGLATRVIEVRPDGTLTDYLGTYDEYLQSQGVEV
HHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGSDLEPSAGNVML
CCCCCEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
EPGVRLGKLRQDQFAYEDMRVLDVVMMGHTEMWAAAQERDAIYANPEATDDDYMKAADLE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCHHHHHHCCC
AKYAEYDGYTAEARAGELLLGVGIPIDQHNGPMSSVAPGWKLRVLLAQALFSNPDVLLLD
HHHHHCCCEECCCCCCCEEEEECCEECCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDINTIRWLESVLNERNSTMIIISHDRHFLNSVCTHMADMDYGTLKVYPGNYDDY
CCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHH
MEASIQARERLQAANARAKERISDLQDFVRRFSANKSKARQATSRLKMIDKIKVEDIKPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCC
SRQNPFIRFEFEKKLHNLAVEAENARKTYDRKIFDGLTMAVRAGEKIAIIGENGAGKTTL
CCCCCEEEEEHHHHHHHHHEECHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCHHHH
LRSLLNHSVKTGVQRGIDVDGGIIKWAEHANVGYMPQDTYEEFPEDRDLMDWMSQWTQAG
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCC
DDDQSLRGTMGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLALDEPTNHMDME
CCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCCCCHH
SIESLQVALDKFEGTLIFVSHDREFVSGLATRVIEVRPDGTLTDYLGTYDEYLQSQGVEV
HHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]