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The map label for this gene is tadA [H]

Identifier: 17546170

GI number: 17546170

Start: 1552553

End: 1553104

Strand: Direct

Name: tadA [H]

Synonym: RSc1451

Alternate gene names: 17546170

Gene position: 1552553-1553104 (Clockwise)

Preceding gene: 17546169

Following gene: 17546171

Centisome position: 41.78

GC content: 72.28

Gene sequence:

>552_bases
ATGACGACTCCCCACGTGCTGACGCCGCCGCCAGGCATGTCCGCCCACGAGCGCGACGGCTACTGGATGCAGCAGGCGCT
GGTGCAGGCCCGTCTGGCGTGGGGCGAGGGCGAGGTGCCGGTGGGCGCGGTGGTGGTGCGGGGCAACGAGATCGTCGGGG
TCGGCTATAACGCGCCGATCGGTACGCACGATCCGTCCGCCCATGCCGAGATGCGCGCGCTGCGGCAGGCCGCCGTCAGG
CTGGGCAATTACCGCCTGCCCGAATGCGAAGTGTTCGTGACGCTGGAGCCGTGCGTGATGTGCGCGGGCGCCATGCTGCA
CGCCCGCGTGGCGCGCGTCGTCTACGGCGCGCCCGATCCCAAGACCGGCGCGGCCGGCAGCGTGCTGGACCTGTTTGCCG
AGACGCGCCTGAACCACCAGACCGCCATCATCGGCAGCGTGCTCGCGCAGGACTGCGGCGACATGCTGCGCGCCTTCTTC
GCCGAGCGCCGCGCCAGCCAGCGCGCCGCGCGCATGGCCTCCGCCTCCGACGATTCCGCTTCCGCCGCATGA

Upstream 100 bases:

>100_bases
CGGCTGTCCAAGCTGGTGCTGTACGAAACTCCCAATTGCTGGGCGGATGTGAAGCTCGCGCGTCCGCACGAGCAGGATTG
ACCCGGCCCATCCGACCCGC

Downstream 100 bases:

>100_bases
CCACTGTCCGCCTGATCGCGCCCTCCGGCTATCCGAACGATTCCGCCATCGCCGAGCGTGGCGTGGCGTTCCTGCAGGGG
CAGGGCTGCGCGGTGGTCAA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTTPHVLTPPPGMSAHERDGYWMQQALVQARLAWGEGEVPVGAVVVRGNEIVGVGYNAPIGTHDPSAHAEMRALRQAAVR
LGNYRLPECEVFVTLEPCVMCAGAMLHARVARVVYGAPDPKTGAAGSVLDLFAETRLNHQTAIIGSVLAQDCGDMLRAFF
AERRASQRAARMASASDDSASAA

Sequences:

>Translated_183_residues
MTTPHVLTPPPGMSAHERDGYWMQQALVQARLAWGEGEVPVGAVVVRGNEIVGVGYNAPIGTHDPSAHAEMRALRQAAVR
LGNYRLPECEVFVTLEPCVMCAGAMLHARVARVVYGAPDPKTGAAGSVLDLFAETRLNHQTAIIGSVLAQDCGDMLRAFF
AERRASQRAARMASASDDSASAA
>Mature_182_residues
TTPHVLTPPPGMSAHERDGYWMQQALVQARLAWGEGEVPVGAVVVRGNEIVGVGYNAPIGTHDPSAHAEMRALRQAAVRL
GNYRLPECEVFVTLEPCVMCAGAMLHARVARVVYGAPDPKTGAAGSVLDLFAETRLNHQTAIIGSVLAQDCGDMLRAFFA
ERRASQRAARMASASDDSASAA

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=160, Percent_Identity=33.75, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI145693172, Length=158, Percent_Identity=52.5316455696203, Blast_Score=181, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17541138, Length=155, Percent_Identity=34.8387096774194, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=37.1134020618557, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=79, Percent_Identity=41.7721518987342, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=33.7931034482759, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19438; Mature: 19307

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPHVLTPPPGMSAHERDGYWMQQALVQARLAWGEGEVPVGAVVVRGNEIVGVGYNAPI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCC
GTHDPSAHAEMRALRQAAVRLGNYRLPECEVFVTLEPCVMCAGAMLHARVARVVYGAPDP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCC
KTGAAGSVLDLFAETRLNHQTAIIGSVLAQDCGDMLRAFFAERRASQRAARMASASDDSA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SAA
CCC
>Mature Secondary Structure 
TTPHVLTPPPGMSAHERDGYWMQQALVQARLAWGEGEVPVGAVVVRGNEIVGVGYNAPI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCC
GTHDPSAHAEMRALRQAAVRLGNYRLPECEVFVTLEPCVMCAGAMLHARVARVVYGAPDP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCC
KTGAAGSVLDLFAETRLNHQTAIIGSVLAQDCGDMLRAFFAERRASQRAARMASASDDSA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]