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The map label for this gene is hexR [H]

Identifier: 17546096

GI number: 17546096

Start: 1467553

End: 1468551

Strand: Direct

Name: hexR [H]

Synonym: RSc1377

Alternate gene names: 17546096

Gene position: 1467553-1468551 (Clockwise)

Preceding gene: 17546093

Following gene: 17546097

Centisome position: 39.49

GC content: 72.97

Gene sequence:

>999_bases
ATGGCGAAGCCTTCCCGCAAGCGTCCGGACGCGCAGCAAGCCGCGTTCGCCGCCGATGCGTCGATCTCCGAGCGCATCGC
GGCCGCGCTCGCCACGCTGACGCCGGCGCACCAGCGCATGGCGGAATACGTGCTGGCGAACCCGTTTCGCGCGGCCACCA
TGCGCATCGACGAATTTGCCGAGGCCGTGGGGATGTCGGTGGCGACGGCCAACCGTTTCGCGCATGCGCTGGGCTTCGAC
GGCTATCCGCGCTTTCGCGCCGAGCTGGTGCGCGGCTTCGAGGCGACGCTCGCGCCGGTCGAAAAGCTGCGGCATGAGCT
GGCGCGTCCGGCCAGCAGCGCCGAGATCTTCGCCGCCTCGCTGAACGAAGACATCGGCAACCTGGAGGCCACCCGCCGCA
TGCTCGACCCGGCCGCCTGCGAGCGGGCGGTGGAGGCCATCCTGGCCGCCCCGCGCATCTACGTGGTGGGGTTCGGCGCC
AGCGGCTACCTGGCCGGGCTGCTGCGGCACGGGCTGGATCTGTACTGCGACACGGTGTTGTCGGTGTCGCAGGCGGGCGG
GGCGTCGGACGCGGCGCGGCAACTGCGCAAGATCGCGCCGGACGACCTGCTGATCGCCATCGCCTTTCCGCGCTACGCCG
CCGACACCATCACGCTGGCCAAGCGCGTGCGCGACCACGGCGGCCGCGTGCTGGCGCTGACCGACGGCCCGGCCTCGCCG
CTGGCGCCGCTGGCCGACATCGCACTCTATGCTCGCACGGAGCGGCAGTTTTCCGCCTCGTCCGATTCGGCCACGGTGGC
GCTGATCGAAGCGCTGTGCGGTGCCGTCGCGCATCGCTCGGCGCGTTCGCTGGAATCGGCCGCGAACCTGACCGCCTTCG
TGCTGCCCTGGCTGCATGCGGGCCAGGCGCCGCGCGCCACGCCGGCTGCGCCTGCCGACACGGCCCGCGTGGCCACGGCC
ACCACCCGGCGCGGCCGCAAGCGCGCGTCGGCCGACTGA

Upstream 100 bases:

>100_bases
CGGCGGTTAGGGAAAACCATAGGCCGGTGTGAAAGTTTTTTTCTTTACATGGTGCGATCGTGTAAATACATTTACAGCAA
CCTTCCACGGCCACAGGATC

Downstream 100 bases:

>100_bases
TCCCGAGATTGCCGAGACCGACCCGTATGCCCACCCCGATCCTCGCCATCCATGGCGGCGCCGGCACCATTACCCGGGCG
GCGATGGACGCCGACAAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAKPSRKRPDAQQAAFAADASISERIAAALATLTPAHQRMAEYVLANPFRAATMRIDEFAEAVGMSVATANRFAHALGFD
GYPRFRAELVRGFEATLAPVEKLRHELARPASSAEIFAASLNEDIGNLEATRRMLDPAACERAVEAILAAPRIYVVGFGA
SGYLAGLLRHGLDLYCDTVLSVSQAGGASDAARQLRKIAPDDLLIAIAFPRYAADTITLAKRVRDHGGRVLALTDGPASP
LAPLADIALYARTERQFSASSDSATVALIEALCGAVAHRSARSLESAANLTAFVLPWLHAGQAPRATPAAPADTARVATA
TTRRGRKRASAD

Sequences:

>Translated_332_residues
MAKPSRKRPDAQQAAFAADASISERIAAALATLTPAHQRMAEYVLANPFRAATMRIDEFAEAVGMSVATANRFAHALGFD
GYPRFRAELVRGFEATLAPVEKLRHELARPASSAEIFAASLNEDIGNLEATRRMLDPAACERAVEAILAAPRIYVVGFGA
SGYLAGLLRHGLDLYCDTVLSVSQAGGASDAARQLRKIAPDDLLIAIAFPRYAADTITLAKRVRDHGGRVLALTDGPASP
LAPLADIALYARTERQFSASSDSATVALIEALCGAVAHRSARSLESAANLTAFVLPWLHAGQAPRATPAAPADTARVATA
TTRRGRKRASAD
>Mature_331_residues
AKPSRKRPDAQQAAFAADASISERIAAALATLTPAHQRMAEYVLANPFRAATMRIDEFAEAVGMSVATANRFAHALGFDG
YPRFRAELVRGFEATLAPVEKLRHELARPASSAEIFAASLNEDIGNLEATRRMLDPAACERAVEAILAAPRIYVVGFGAS
GYLAGLLRHGLDLYCDTVLSVSQAGGASDAARQLRKIAPDDLLIAIAFPRYAADTITLAKRVRDHGGRVLALTDGPASPL
APLADIALYARTERQFSASSDSATVALIEALCGAVAHRSARSLESAANLTAFVLPWLHAGQAPRATPAAPADTARVATAT
TRRGRKRASAD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=239, Percent_Identity=28.0334728033473, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 35096; Mature: 34965

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPSRKRPDAQQAAFAADASISERIAAALATLTPAHQRMAEYVLANPFRAATMRIDEFA
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHH
EAVGMSVATANRFAHALGFDGYPRFRAELVRGFEATLAPVEKLRHELARPASSAEIFAAS
HHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LNEDIGNLEATRRMLDPAACERAVEAILAAPRIYVVGFGASGYLAGLLRHGLDLYCDTVL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
SVSQAGGASDAARQLRKIAPDDLLIAIAFPRYAADTITLAKRVRDHGGRVLALTDGPASP
HHHHCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCC
LAPLADIALYARTERQFSASSDSATVALIEALCGAVAHRSARSLESAANLTAFVLPWLHA
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQAPRATPAAPADTARVATATTRRGRKRASAD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKPSRKRPDAQQAAFAADASISERIAAALATLTPAHQRMAEYVLANPFRAATMRIDEFA
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHH
EAVGMSVATANRFAHALGFDGYPRFRAELVRGFEATLAPVEKLRHELARPASSAEIFAAS
HHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LNEDIGNLEATRRMLDPAACERAVEAILAAPRIYVVGFGASGYLAGLLRHGLDLYCDTVL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
SVSQAGGASDAARQLRKIAPDDLLIAIAFPRYAADTITLAKRVRDHGGRVLALTDGPASP
HHHHCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCC
LAPLADIALYARTERQFSASSDSATVALIEALCGAVAHRSARSLESAANLTAFVLPWLHA
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQAPRATPAAPADTARVATATTRRGRKRASAD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]