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The map label for this gene is iolI [H]

Identifier: 17545964

GI number: 17545964

Start: 1320458

End: 1321279

Strand: Direct

Name: iolI [H]

Synonym: RSc1245

Alternate gene names: 17545964

Gene position: 1320458-1321279 (Clockwise)

Preceding gene: 17545963

Following gene: 17545965

Centisome position: 35.53

GC content: 66.67

Gene sequence:

>822_bases
ATGAACCACCGCATCCAATTTGGCATCAACCGGATCAGCGCACCGCGCCAGACGTTTGCCGACTATCTGGCCATGTGCAA
GCGCATCGGCGTTTCGGCCATCGAGATCCGCAACGACCTGAAAGGCGTGGAGATCAGCGACGGCACGCCGGCCGCCGAAC
TGAAGGCGCAGGCCGAGCAGGCCGGTATTGTCATCCGCTCGATCAACGCGCTGTATCCGTTCGACGTGTTCGACGCCGGG
CTCGAGGCCCGGGCGCGCTCGATGGCCGCCTACGCGCGCGCCTGCGGCGCCCAGGCGCTGGTGATGTGCCCGCTCAACAG
CCGGGATGACCAGCGGACCGAGGCCGAGCGCCGCCGGGATCTGGTGCACGCGCTGCGCAGGCTGCGCCCGATTCTGGACG
AGTACGGTATCGAAGGGCTGGTCGAGCCGCTCGGCTTCGAGGAATGCGTCCTGCGCCGCAAGTCCGATGCCGTCGAAGCC
ATCTATGCCGCCGCCGGCGAGCGGCATTTCAAGCTGGTGCACGACACGTTCCACCACCACCTGGCCGGCGAGGACATCTT
CTTTCCCGACCTGACGGGGCTCGTGCATGTGTCGGGCGTCGAATCGGCGGAGCTCGACGCGCGCGACATGCGCGATGGCC
ACCGCGTCCTGGTCGGGCAGGGTGACCGGCTCGGCAATATCGCGCAACTGCGTACGCTGCTCGATCGCGGCTACCGGGGC
CTGGTGTCGTTCGAGCCGTTCGCGGCCGAAGTGATGGAGGCGGAGAACAGCGAGGCGTTGCTTGCCGAGAGCATGCACTA
CATCCACCACGCATTGTCTTGA

Upstream 100 bases:

>100_bases
CGCGGAGGCATCGTCCCGCTTCATGCGCGGTGAACTGCAACGTTACATCGACCGATATTTCCGCGGCGCCGTGCGCTGAA
TCCACCAATCGACCCCAACC

Downstream 100 bases:

>100_bases
CACGCTGGACGACAGGGAAAACGGTATGACTCTGCAAATTGGGGTGATCGGCTGCGGCGCGATCGGCCAGGACCACATCC
GGCGGCTGACGCGCACGTTG

Product: protein implicated IN myo-inositol catabolique pathway

Products: NA

Alternate protein names: 2-keto-myo-inositol isomerase; 2KMI isomerase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MNHRIQFGINRISAPRQTFADYLAMCKRIGVSAIEIRNDLKGVEISDGTPAAELKAQAEQAGIVIRSINALYPFDVFDAG
LEARARSMAAYARACGAQALVMCPLNSRDDQRTEAERRRDLVHALRRLRPILDEYGIEGLVEPLGFEECVLRRKSDAVEA
IYAAAGERHFKLVHDTFHHHLAGEDIFFPDLTGLVHVSGVESAELDARDMRDGHRVLVGQGDRLGNIAQLRTLLDRGYRG
LVSFEPFAAEVMEAENSEALLAESMHYIHHALS

Sequences:

>Translated_273_residues
MNHRIQFGINRISAPRQTFADYLAMCKRIGVSAIEIRNDLKGVEISDGTPAAELKAQAEQAGIVIRSINALYPFDVFDAG
LEARARSMAAYARACGAQALVMCPLNSRDDQRTEAERRRDLVHALRRLRPILDEYGIEGLVEPLGFEECVLRRKSDAVEA
IYAAAGERHFKLVHDTFHHHLAGEDIFFPDLTGLVHVSGVESAELDARDMRDGHRVLVGQGDRLGNIAQLRTLLDRGYRG
LVSFEPFAAEVMEAENSEALLAESMHYIHHALS
>Mature_273_residues
MNHRIQFGINRISAPRQTFADYLAMCKRIGVSAIEIRNDLKGVEISDGTPAAELKAQAEQAGIVIRSINALYPFDVFDAG
LEARARSMAAYARACGAQALVMCPLNSRDDQRTEAERRRDLVHALRRLRPILDEYGIEGLVEPLGFEECVLRRKSDAVEA
IYAAAGERHFKLVHDTFHHHLAGEDIFFPDLTGLVHVSGVESAELDARDMRDGHRVLVGQGDRLGNIAQLRTLLDRGYRG
LVSFEPFAAEVMEAENSEALLAESMHYIHHALS

Specific function: Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6/3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5/4,6- pentahydroxycyclohexanone) [H]

COG id: COG4130

COG function: function code G; Predicted sugar epimerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolI family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: NA

Molecular weight: Translated: 30359; Mature: 30359

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHRIQFGINRISAPRQTFADYLAMCKRIGVSAIEIRNDLKGVEISDGTPAAELKAQAEQ
CCCEEEECHHHHCCCHHHHHHHHHHHHHHCCHHEEHHHCCCCCEECCCCCHHHHHHHHHH
AGIVIRSINALYPFDVFDAGLEARARSMAAYARACGAQALVMCPLNSRDDQRTEAERRRD
HCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
LVHALRRLRPILDEYGIEGLVEPLGFEECVLRRKSDAVEAIYAAAGERHFKLVHDTFHHH
HHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAGEDIFFPDLTGLVHVSGVESAELDARDMRDGHRVLVGQGDRLGNIAQLRTLLDRGYRG
HCCCCCCCCCCCCEEEECCCCCHHCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
LVSFEPFAAEVMEAENSEALLAESMHYIHHALS
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHRIQFGINRISAPRQTFADYLAMCKRIGVSAIEIRNDLKGVEISDGTPAAELKAQAEQ
CCCEEEECHHHHCCCHHHHHHHHHHHHHHCCHHEEHHHCCCCCEECCCCCHHHHHHHHHH
AGIVIRSINALYPFDVFDAGLEARARSMAAYARACGAQALVMCPLNSRDDQRTEAERRRD
HCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
LVHALRRLRPILDEYGIEGLVEPLGFEECVLRRKSDAVEAIYAAAGERHFKLVHDTFHHH
HHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAGEDIFFPDLTGLVHVSGVESAELDARDMRDGHRVLVGQGDRLGNIAQLRTLLDRGYRG
HCCCCCCCCCCCCEEEECCCCCHHCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
LVSFEPFAAEVMEAENSEALLAESMHYIHHALS
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]