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The map label for this gene is tcp [H]

Identifier: 17545875

GI number: 17545875

Start: 1215097

End: 1216899

Strand: Direct

Name: tcp [H]

Synonym: RSc1156

Alternate gene names: 17545875

Gene position: 1215097-1216899 (Clockwise)

Preceding gene: 17545874

Following gene: 17545878

Centisome position: 32.7

GC content: 70.49

Gene sequence:

>1803_bases
GTGGAACGCTTCCTGAAAAACACCAGTGTGCGAGCCGGCCTGCTGGCGATTCTGGTGACCTTTGCACTGATGATCGTGGT
GGGCGCGGCGGTCGGCGTGCTGGCCCTGAGCACGGCCAACGTATCGACCGAGCGCGTGCATGCCATCTCGGCACGCAGCA
TGCTGCTCAATGACGCCTACAAGGACATGATGCGCGCCCGCACCGGGCTGGCGCGCGTCTACGGCATGCTGCGCGAGAAT
CCCGGCACGCCCTTGGCGTCCAACGCGCTCGATAGCGCCGAGTCGGGCGTGAAGAAATCGCTCGCCCAGCTCGACGCGTT
CAAGAGTGCGCCGGCCATCGAAGGCGTGGATCAGGCCCTGCGCCAGGCCGCCGCCCAGGCCGCGCAGGCGCATGCCGACG
CCGTGCAGCGCGCCATGGCCGCCCTGCGCGCCAGCGATGCGGCCGCCTACGCCACCATCAACGCCAAGGACGTCACCTCA
TCGGGGGCGGCCTGGTCGGTCGAGATCGAACGCTTCCAGAAGCTCAGCAGCCAACTGGCCCAGGAAGAGGCTGACGGCGG
GCAGGCGCGCTACGGCCTGATCGTCAAGTTCGTGAGCGTCGGCATCGTCATGGCGCTGGCGTTGATTGCCGCCGTGCACT
ACGCGCTCAAAGCCTTCGTGGTGACGCCGCTCAACGACGCGGTGGATGTGCTGACGCGCGTGGCCGAGGGCGATCTGTCT
GTGCAGGTGAGGGAAGGCGGACGCAACGAGCTGGGCCGGCTGCTGTCGGCCGTGGCCCGCATGCGCGCCAGCCTGCTGCA
GACGGTGCGCCAGGTGCGCAGCAGCTCGGACGCGGTCAACACCGGCGCGCACGAGATCGCCAGCGGCAACCTCGATCTGT
CGTCGCGGACCGAGCAGCAGTCGGCGTCGCTGGAGAAGACGGCCGCCAGCATGGAGCAGATGACCTCCACCGTCACCAAC
AACTCCGAGAACGCTCGCCAGGCCAGCGCGCTCGCGGCCAGCGCGGCCGACCTGGCCTCGCGCGGCGGCGAGGTGGTGCG
CGGCGTGGTCTCGACCATGGACGAGATCAGCGCGAGCTCGCGCAAGATGGCCGACATCATCGGCGTGATCGACGGCATCG
CCTTCCAGACCAATATCCTGGCGCTCAACGCGGCGGTGGAAGCCGCCCGCGCCGGCGAGCAGGGGCGCGGCTTCGCCGTG
GTGGCCGGCGAGGTGCGGGCCCTGGCCCAGCGCAGCGCGGCCGCCGCCAAGGAGATCAAGGACCTGATCGATGCCTCGGT
CGATCGCGTGCAGGCCGGCAACACGCTGGTGGCCCAGGCGGGTTCGACCATGACCGAGACGGTGGATGCGGTGCGCCGCG
TGGCCAATATCGTCGAAGACATTGCCGCCGCCTCGTCCGAGCAGACGCAGGGCATCCTGCAGATCAGCCAGGCGGTGTCG
GAGATGGAGCAGGTGACGCAGCAGAACGCCGCGCTGGTCGAGCAGGCCGCGGCCGCCGCGCAGTCGCTGGAGGAGCAGTC
GCTGAACCTGACCCACGTGGTGGCCCAGTTCCGGCTGGACGAGACGGACGGTGTGGTGGCGGCTGCCGCGTCCAAGCCGG
TGCGTACCGCGCCGGCTGCCGCCGTGAAGCCGGCCGCCAAGCCGCCGCGCCCGGTCGTGCGCAAGCGTGGGCCCAGCCCC
AAGGCCGTGGCGCCGGCCACCGTGCCTGTCGTTGCGCCCGCTGCCGCGCCTGTCGTTGCGCCGGTCAAGGCCCAGCCGCT
GGCCGCCGTCGCCGGCTCGGACGGCGACTGGGAAACCTTCTGA

Upstream 100 bases:

>100_bases
CGATGCCGACTGGGAAACCTTCTGAACCGTCCGGCGCGGCAACGCGCCGGCCTGACCCCGGCCCCGCACCTGGAATGCGG
GCCGGTCTCCGGAGACAACT

Downstream 100 bases:

>100_bases
TCGTCGGATCAGGCCTGCGGCGCGCGGCCCGAGGGCTCGCGCGCCGGGCCTTCGATCCGCTTGTCCCAGCTTTCCACCTC
GCCGCGTGCCAGCCGGTTCT

Product: methyl-accepting chemotaxis transducer transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MERFLKNTSVRAGLLAILVTFALMIVVGAAVGVLALSTANVSTERVHAISARSMLLNDAYKDMMRARTGLARVYGMLREN
PGTPLASNALDSAESGVKKSLAQLDAFKSAPAIEGVDQALRQAAAQAAQAHADAVQRAMAALRASDAAAYATINAKDVTS
SGAAWSVEIERFQKLSSQLAQEEADGGQARYGLIVKFVSVGIVMALALIAAVHYALKAFVVTPLNDAVDVLTRVAEGDLS
VQVREGGRNELGRLLSAVARMRASLLQTVRQVRSSSDAVNTGAHEIASGNLDLSSRTEQQSASLEKTAASMEQMTSTVTN
NSENARQASALAASAADLASRGGEVVRGVVSTMDEISASSRKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRALAQRSAAAAKEIKDLIDASVDRVQAGNTLVAQAGSTMTETVDAVRRVANIVEDIAAASSEQTQGILQISQAVS
EMEQVTQQNAALVEQAAAAAQSLEEQSLNLTHVVAQFRLDETDGVVAAAASKPVRTAPAAAVKPAAKPPRPVVRKRGPSP
KAVAPATVPVVAPAAAPVVAPVKAQPLAAVAGSDGDWETF

Sequences:

>Translated_600_residues
MERFLKNTSVRAGLLAILVTFALMIVVGAAVGVLALSTANVSTERVHAISARSMLLNDAYKDMMRARTGLARVYGMLREN
PGTPLASNALDSAESGVKKSLAQLDAFKSAPAIEGVDQALRQAAAQAAQAHADAVQRAMAALRASDAAAYATINAKDVTS
SGAAWSVEIERFQKLSSQLAQEEADGGQARYGLIVKFVSVGIVMALALIAAVHYALKAFVVTPLNDAVDVLTRVAEGDLS
VQVREGGRNELGRLLSAVARMRASLLQTVRQVRSSSDAVNTGAHEIASGNLDLSSRTEQQSASLEKTAASMEQMTSTVTN
NSENARQASALAASAADLASRGGEVVRGVVSTMDEISASSRKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRALAQRSAAAAKEIKDLIDASVDRVQAGNTLVAQAGSTMTETVDAVRRVANIVEDIAAASSEQTQGILQISQAVS
EMEQVTQQNAALVEQAAAAAQSLEEQSLNLTHVVAQFRLDETDGVVAAAASKPVRTAPAAAVKPAAKPPRPVVRKRGPSP
KAVAPATVPVVAPAAAPVVAPVKAQPLAAVAGSDGDWETF
>Mature_600_residues
MERFLKNTSVRAGLLAILVTFALMIVVGAAVGVLALSTANVSTERVHAISARSMLLNDAYKDMMRARTGLARVYGMLREN
PGTPLASNALDSAESGVKKSLAQLDAFKSAPAIEGVDQALRQAAAQAAQAHADAVQRAMAALRASDAAAYATINAKDVTS
SGAAWSVEIERFQKLSSQLAQEEADGGQARYGLIVKFVSVGIVMALALIAAVHYALKAFVVTPLNDAVDVLTRVAEGDLS
VQVREGGRNELGRLLSAVARMRASLLQTVRQVRSSSDAVNTGAHEIASGNLDLSSRTEQQSASLEKTAASMEQMTSTVTN
NSENARQASALAASAADLASRGGEVVRGVVSTMDEISASSRKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRALAQRSAAAAKEIKDLIDASVDRVQAGNTLVAQAGSTMTETVDAVRRVANIVEDIAAASSEQTQGILQISQAVS
EMEQVTQQNAALVEQAAAAAQSLEEQSLNLTHVVAQFRLDETDGVVAAAASKPVRTAPAAAVKPAAKPPRPVVRKRGPSP
KAVAPATVPVVAPAAAPVVAPVKAQPLAAVAGSDGDWETF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=615, Percent_Identity=41.7886178861789, Blast_Score=337, Evalue=2e-93,
Organism=Escherichia coli, GI1788195, Length=387, Percent_Identity=51.6795865633075, Blast_Score=331, Evalue=9e-92,
Organism=Escherichia coli, GI1787690, Length=429, Percent_Identity=46.6200466200466, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1788194, Length=386, Percent_Identity=50.7772020725389, Blast_Score=306, Evalue=3e-84,
Organism=Escherichia coli, GI1789453, Length=307, Percent_Identity=40.0651465798046, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62005; Mature: 62005

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFLKNTSVRAGLLAILVTFALMIVVGAAVGVLALSTANVSTERVHAISARSMLLNDAY
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KDMMRARTGLARVYGMLRENPGTPLASNALDSAESGVKKSLAQLDAFKSAPAIEGVDQAL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RQAAAQAAQAHADAVQRAMAALRASDAAAYATINAKDVTSSGAAWSVEIERFQKLSSQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECHHHCCCCCCEEEHHHHHHHHHHHHHH
QEEADGGQARYGLIVKFVSVGIVMALALIAAVHYALKAFVVTPLNDAVDVLTRVAEGDLS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCE
VQVREGGRNELGRLLSAVARMRASLLQTVRQVRSSSDAVNTGAHEIASGNLDLSSRTEQQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHH
SASLEKTAASMEQMTSTVTNNSENARQASALAASAADLASRGGEVVRGVVSTMDEISASS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSAAAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLIDASVDRVQAGNTLVAQAGSTMTETVDAVRRVANIVEDIAAASSEQTQGILQISQAVS
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EMEQVTQQNAALVEQAAAAAQSLEEQSLNLTHVVAQFRLDETDGVVAAAASKPVRTAPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
AVKPAAKPPRPVVRKRGPSPKAVAPATVPVVAPAAAPVVAPVKAQPLAAVAGSDGDWETF
HCCCCCCCCCHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCCC
>Mature Secondary Structure
MERFLKNTSVRAGLLAILVTFALMIVVGAAVGVLALSTANVSTERVHAISARSMLLNDAY
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KDMMRARTGLARVYGMLRENPGTPLASNALDSAESGVKKSLAQLDAFKSAPAIEGVDQAL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RQAAAQAAQAHADAVQRAMAALRASDAAAYATINAKDVTSSGAAWSVEIERFQKLSSQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECHHHCCCCCCEEEHHHHHHHHHHHHHH
QEEADGGQARYGLIVKFVSVGIVMALALIAAVHYALKAFVVTPLNDAVDVLTRVAEGDLS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCE
VQVREGGRNELGRLLSAVARMRASLLQTVRQVRSSSDAVNTGAHEIASGNLDLSSRTEQQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHH
SASLEKTAASMEQMTSTVTNNSENARQASALAASAADLASRGGEVVRGVVSTMDEISASS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSAAAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLIDASVDRVQAGNTLVAQAGSTMTETVDAVRRVANIVEDIAAASSEQTQGILQISQAVS
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EMEQVTQQNAALVEQAAAAAQSLEEQSLNLTHVVAQFRLDETDGVVAAAASKPVRTAPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
AVKPAAKPPRPVVRKRGPSPKAVAPATVPVVAPAAAPVVAPVKAQPLAAVAGSDGDWETF
HCCCCCCCCCHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]