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The map label for this gene is rbsK [H]

Identifier: 17545732

GI number: 17545732

Start: 1066264

End: 1067211

Strand: Reverse

Name: rbsK [H]

Synonym: RSc1013

Alternate gene names: 17545732

Gene position: 1067211-1066264 (Counterclockwise)

Preceding gene: 17545733

Following gene: 17545729

Centisome position: 28.72

GC content: 72.78

Gene sequence:

>948_bases
ATGGTGGCCAAGCGTTCCGTTCTCTCCTCGGCCGCTGCCGACGTGCTGGTCGTCGGCAGCCTCAACATGGATCTCGTGAT
CCGCACCCCTTGTTTGCCCCGTCCGGGGCAAACGGTTGCCGCGCCGGCGCTGGAAACCATCCCCGGCGGCAAAGGCGCCA
ACCAGGCCGTGGCCTCGGCGCGCCTGGGCAGCCGCGTCGCCATGCTCGGCTGCGTGGGCGACGACCCCCACGGCATGGCC
CTGCGCGAAGGCCTGCTGCGGGAAGGCGTCGATACCGCGATGGTGACCGCGCATGCGGGCGCGCCCACGGGCATCGCCTG
CGTGACGGTGGCCGACAACGGTCAGAACACCATCGTGATCGTGGCCGGCGCCAACCGGCAGCTGACCCCGGCGATGATCG
ACGCACAGCGGGCCGCCTTCGAGCGGGCCAAGGTCATCGTCTGCCAGTTGGAATCGCCGCCGGACGCGGTGGAGCGCGCG
CTGCTGCTCGGGCAGCGGCTGGGCAAGACCGTCATCCTGAACCCGGCGCCCGCCGCCGGTCCGCTGCCGACGCCGTGGCT
CGCCGCCTGCGACTACCTGATCCCCAACGAGACCGAAGCCGCGCTGCTGACGGCGCGGCGGGTGGATTCGCCCGAAGCGG
CACTGAACGCCGCCGCCGATCTGCATGCGCAGGGCGCGCGCCACGTCATCGTCACGCTGGGCGCGCGCGGCGTCGCCTAC
GTGGATGCGACCACCCGCCTGCTGATGCCCGCCCATCCCGCGCAGGCCATCGACACCACCGCGGCCGGCGATACCTTCGT
CGGCGCGCTGGCCACGGCGCTGGCGGAGGGCGCGGCGCCGGTCGAGGCGATCCAGTTCGGCCTGGCCGCGGCCGCGGTGT
CGGTCACGCGGCTGGGTGCGCAGCCCTCGATTCCGTTCCGCAGCGAACTGGCCTCACCGGTGCAATAG

Upstream 100 bases:

>100_bases
GCCGCCGCGCCTGTCGCTGCGCGAGTCGACCGCCGAGCCCGCACGCCCCGCGCGCGCGGCCTAAACTCCAGTCAACAGAA
ACCGCAACCCTTTGCCCACC

Downstream 100 bases:

>100_bases
TGCGGACCGCCCCCCTCGGGGGCGGTTCAGGCCGGCGTGCCGGCAGTGGGCGGGGCCGGCTCGGTCGGCGCGCGCGGCAC
CAGCAGGCACAGCGGATCGC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MVAKRSVLSSAAADVLVVGSLNMDLVIRTPCLPRPGQTVAAPALETIPGGKGANQAVASARLGSRVAMLGCVGDDPHGMA
LREGLLREGVDTAMVTAHAGAPTGIACVTVADNGQNTIVIVAGANRQLTPAMIDAQRAAFERAKVIVCQLESPPDAVERA
LLLGQRLGKTVILNPAPAAGPLPTPWLAACDYLIPNETEAALLTARRVDSPEAALNAAADLHAQGARHVIVTLGARGVAY
VDATTRLLMPAHPAQAIDTTAAGDTFVGALATALAEGAAPVEAIQFGLAAAAVSVTRLGAQPSIPFRSELASPVQ

Sequences:

>Translated_315_residues
MVAKRSVLSSAAADVLVVGSLNMDLVIRTPCLPRPGQTVAAPALETIPGGKGANQAVASARLGSRVAMLGCVGDDPHGMA
LREGLLREGVDTAMVTAHAGAPTGIACVTVADNGQNTIVIVAGANRQLTPAMIDAQRAAFERAKVIVCQLESPPDAVERA
LLLGQRLGKTVILNPAPAAGPLPTPWLAACDYLIPNETEAALLTARRVDSPEAALNAAADLHAQGARHVIVTLGARGVAY
VDATTRLLMPAHPAQAIDTTAAGDTFVGALATALAEGAAPVEAIQFGLAAAAVSVTRLGAQPSIPFRSELASPVQ
>Mature_315_residues
MVAKRSVLSSAAADVLVVGSLNMDLVIRTPCLPRPGQTVAAPALETIPGGKGANQAVASARLGSRVAMLGCVGDDPHGMA
LREGLLREGVDTAMVTAHAGAPTGIACVTVADNGQNTIVIVAGANRQLTPAMIDAQRAAFERAKVIVCQLESPPDAVERA
LLLGQRLGKTVILNPAPAAGPLPTPWLAACDYLIPNETEAALLTARRVDSPEAALNAAADLHAQGARHVIVTLGARGVAY
VDATTRLLMPAHPAQAIDTTAAGDTFVGALATALAEGAAPVEAIQFGLAAAAVSVTRLGAQPSIPFRSELASPVQ

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=39.1891891891892, Blast_Score=169, Evalue=4e-42,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=45.3333333333333, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI87082343, Length=291, Percent_Identity=29.8969072164948, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788484, Length=285, Percent_Identity=28.4210526315789, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081971, Length=279, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788491, Length=291, Percent_Identity=25.4295532646048, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788017, Length=272, Percent_Identity=26.8382352941176, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=304, Percent_Identity=37.5, Blast_Score=174, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=30.7228915662651, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=37.785016286645, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24583886, Length=308, Percent_Identity=33.7662337662338, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31944; Mature: 31944

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKRSVLSSAAADVLVVGSLNMDLVIRTPCLPRPGQTVAAPALETIPGGKGANQAVASA
CCCHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCEEECCHHHHCCCCCCCHHHHHHH
RLGSRVAMLGCVGDDPHGMALREGLLREGVDTAMVTAHAGAPTGIACVTVADNGQNTIVI
HHCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCEEEEE
VAGANRQLTPAMIDAQRAAFERAKVIVCQLESPPDAVERALLLGQRLGKTVILNPAPAAG
EECCCCCCCHHHHHHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCCC
PLPTPWLAACDYLIPNETEAALLTARRVDSPEAALNAAADLHAQGARHVIVTLGARGVAY
CCCCCHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
VDATTRLLMPAHPAQAIDTTAAGDTFVGALATALAEGAAPVEAIQFGLAAAAVSVTRLGA
EECHHEEEECCCCHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
QPSIPFRSELASPVQ
CCCCCHHHHHCCCCC
>Mature Secondary Structure
MVAKRSVLSSAAADVLVVGSLNMDLVIRTPCLPRPGQTVAAPALETIPGGKGANQAVASA
CCCHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCEEECCHHHHCCCCCCCHHHHHHH
RLGSRVAMLGCVGDDPHGMALREGLLREGVDTAMVTAHAGAPTGIACVTVADNGQNTIVI
HHCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCEEEEE
VAGANRQLTPAMIDAQRAAFERAKVIVCQLESPPDAVERALLLGQRLGKTVILNPAPAAG
EECCCCCCCHHHHHHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCCC
PLPTPWLAACDYLIPNETEAALLTARRVDSPEAALNAAADLHAQGARHVIVTLGARGVAY
CCCCCHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
VDATTRLLMPAHPAQAIDTTAAGDTFVGALATALAEGAAPVEAIQFGLAAAAVSVTRLGA
EECHHEEEECCCCHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
QPSIPFRSELASPVQ
CCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]