Click here to switch to the map view.

The map label for this gene is ubiG [H]

Identifier: 17545617

GI number: 17545617

Start: 947840

End: 948622

Strand: Reverse

Name: ubiG [H]

Synonym: RSc0898

Alternate gene names: 17545617

Gene position: 948622-947840 (Counterclockwise)

Preceding gene: 17545619

Following gene: 17545616

Centisome position: 25.53

GC content: 64.24

Gene sequence:

>783_bases
TTGGTCCGGACAAGGCTTTTTGGTACATTTCCTCACCTCAGCCGTTCAGCACAGGCGCAGCGCAACATGACGACGACTTA
CGCGAACGCCGATCCTGGCGAACTCGAAAAATTCAGCGAACTCGCCCACCGCTGGTGGGATCCGAACAGCGAGTTCAAGC
CACTGCACGAAATCAATCCGCTGCGCCTCGACTGGATCCAATCCACGGCGCCGCTGGCGGGCAAGCGTGTGGTCGATGTC
GGCTGCGGCGGCGGCATCCTCTCCGAAAGCATGGCGCGCGCCGGGGCCAACGTCAAAGGCATCGACCTGTCGCGCAAGGC
CTTGCGCGTGGCCGACCTCCACAGCCTGGAAGCCGGCGTGGCGGTCGACTACGAGGAGATCGCCGCGGAAGCCCTCGCAG
CACGCGAACCGGGCAGCTTCGATGTCGTGACTTGCATGGAAATGCTTGAACATGTGCCCGATCCCGCCTCGGTTGTCCGA
GCTTGCGCGACCTTGGTCAAGCCCGGCGGCCATGTCTTCTTCTCGACCATCCATCGCAATGCCAAGGCCTATCTGCTGGC
GGTGATCGGTGCCGAGTATGTGCTCAACATGCTGCCGCGCGGTACGCACGACTACGCCAAGTTCATCCGCCCGTCGGAGC
TGGCGGGATTTGCCCGCACGGCCGGACTGGAGCCGGCGCAGTTGCGCGGCCTCGAATACAACCCGCTCACGGGCCGCTAC
GCGCTGACGCACGACACCAGCGTCAACTACCTGATAGCGACCCGCCGGCCGGACGCGCCATGA

Upstream 100 bases:

>100_bases
TTCATGATTTCTCCCAGAGCAAGGGTGACAATTGGAGAGCGTAAGCGCACGTTTGTTCGTTCCTGTTTCAATATGAAACG
CTTTTATCGCGCGAGGTGAT

Downstream 100 bases:

>100_bases
CCACGACGAGGTTTCCCGATCCGCTGGGCGCGGTGCTGTTCGACCTGGACGGCACGCTGGCCGATACGGCGCCGGACCTG
GCCGCAGCGGCCAACAAGGT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MVRTRLFGTFPHLSRSAQAQRNMTTTYANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLDWIQSTAPLAGKRVVDV
GCGGGILSESMARAGANVKGIDLSRKALRVADLHSLEAGVAVDYEEIAAEALAAREPGSFDVVTCMEMLEHVPDPASVVR
ACATLVKPGGHVFFSTIHRNAKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELAGFARTAGLEPAQLRGLEYNPLTGRY
ALTHDTSVNYLIATRRPDAP

Sequences:

>Translated_260_residues
MVRTRLFGTFPHLSRSAQAQRNMTTTYANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLDWIQSTAPLAGKRVVDV
GCGGGILSESMARAGANVKGIDLSRKALRVADLHSLEAGVAVDYEEIAAEALAAREPGSFDVVTCMEMLEHVPDPASVVR
ACATLVKPGGHVFFSTIHRNAKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELAGFARTAGLEPAQLRGLEYNPLTGRY
ALTHDTSVNYLIATRRPDAP
>Mature_260_residues
MVRTRLFGTFPHLSRSAQAQRNMTTTYANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLDWIQSTAPLAGKRVVDV
GCGGGILSESMARAGANVKGIDLSRKALRVADLHSLEAGVAVDYEEIAAEALAAREPGSFDVVTCMEMLEHVPDPASVVR
ACATLVKPGGHVFFSTIHRNAKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELAGFARTAGLEPAQLRGLEYNPLTGRY
ALTHDTSVNYLIATRRPDAP

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=244, Percent_Identity=33.6065573770492, Blast_Score=171, Evalue=6e-43,
Organism=Escherichia coli, GI1788564, Length=228, Percent_Identity=57.4561403508772, Blast_Score=278, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI115533050, Length=236, Percent_Identity=34.3220338983051, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324476, Length=295, Percent_Identity=32.2033898305085, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281365311, Length=279, Percent_Identity=30.4659498207885, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24585589, Length=275, Percent_Identity=31.2727272727273, Blast_Score=127, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 28451; Mature: 28451

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTRLFGTFPHLSRSAQAQRNMTTTYANADPGELEKFSELAHRWWDPNSEFKPLHEINP
CCCCCEECCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
LRLDWIQSTAPLAGKRVVDVGCGGGILSESMARAGANVKGIDLSRKALRVADLHSLEAGV
CEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCC
AVDYEEIAAEALAAREPGSFDVVTCMEMLEHVPDPASVVRACATLVKPGGHVFFSTIHRN
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHCC
AKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELAGFARTAGLEPAQLRGLEYNPLTGRY
CHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCE
ALTHDTSVNYLIATRRPDAP
EEEECCCCEEEEEECCCCCC
>Mature Secondary Structure
MVRTRLFGTFPHLSRSAQAQRNMTTTYANADPGELEKFSELAHRWWDPNSEFKPLHEINP
CCCCCEECCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
LRLDWIQSTAPLAGKRVVDVGCGGGILSESMARAGANVKGIDLSRKALRVADLHSLEAGV
CEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCC
AVDYEEIAAEALAAREPGSFDVVTCMEMLEHVPDPASVVRACATLVKPGGHVFFSTIHRN
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHCC
AKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELAGFARTAGLEPAQLRGLEYNPLTGRY
CHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCE
ALTHDTSVNYLIATRRPDAP
EEEECCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]