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The map label for this gene is pcaR [H]

Identifier: 17545476

GI number: 17545476

Start: 800954

End: 801775

Strand: Direct

Name: pcaR [H]

Synonym: RSc0757

Alternate gene names: 17545476

Gene position: 800954-801775 (Clockwise)

Preceding gene: 17545473

Following gene: 17545480

Centisome position: 21.55

GC content: 72.02

Gene sequence:

>822_bases
ATGCGTACCGAGAGTCTCCCCGATACCGAATCCGGCGCCGGACGCGAAGGCGATCCGAACTTCGTCACGGCCCTGGCGCG
CGGGCTGGAACTGCTGCGCGCGTTCCGCCCCGGCGACACGCTGCTCGGCAACCAGGAGTTCGTGCGCCGCACCGGCTTTC
CCAAGGCCACCGTCAGCCGGCTGGCCGGTACGCTGGTCGCGCTCGGCTACCTGCGCTATGACGATGCGCTTGGCAAGTAC
GGGCTCGACGCGGGCGTGCTGGCGCTGGGGTTCGCCTACCTGGCTTCGAGCGACGTGGTGCAGCTGGCGCGTCCGCACAT
GAGCGCGTTCGCGCAGCGGCACGGCGTGTCGATTTCGCTCGGCCGACGCGAGCGGCTGGACATGGTCTACCTGGAAACGA
TCCGCCACGACAGCCCGGCAATGGGCGGCTCGTCGGGGCTGGGTGTGGGCTCGCGGCTGTCGATGCTGTCGAGCTCGATG
GGGCGGGCCTATCTGGCCGCGCTGCCGGCGGCGCGGCGCGAGCGGCGATACGACGCGCTGCGCACGCAGCAGCCCGCGCA
ATGGGCCGCCGAGGGCGCGGCTGCCACGGATGCGGTCAAGGCCGGCGTCCGCGAGGGCTACGCGGTGTCGCTGCGCGAGT
GGCATCCTGCCATCCACGCCTGCGCGGTGGCGTTTTTCGTGCCGGGCCAGCGCGAGCCCTATGTGGTCAGCTGCAGCGCG
CCGCATACGGCGGCCGATGCCGGGCGCATCCGCGCCGAACTGGTGCCCGCCTTGCGGGAACTGGCGGCGCGGCTGGGGCA
GTTGGCCCAACCGACCGGATAA

Upstream 100 bases:

>100_bases
GGATCGGATCTCTGCACTGTGGTTCCGTAATACGGAACAGTGTTTCGAAATTTAGGTTTATCATAACGCAGCCGACGGCA
ATTTCTACTCTTTCCTTGCA

Downstream 100 bases:

>100_bases
GACGCAGCGATCAGAGATCGGTGCGCAGCTTCCACAGTTCCGGAAACAGCACCACGTCCAGCATCTTGCGCAGGTAGTTG
ACGCCTTCGGTGCCGCCGGT

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRTESLPDTESGAGREGDPNFVTALARGLELLRAFRPGDTLLGNQEFVRRTGFPKATVSRLAGTLVALGYLRYDDALGKY
GLDAGVLALGFAYLASSDVVQLARPHMSAFAQRHGVSISLGRRERLDMVYLETIRHDSPAMGGSSGLGVGSRLSMLSSSM
GRAYLAALPAARRERRYDALRTQQPAQWAAEGAAATDAVKAGVREGYAVSLREWHPAIHACAVAFFVPGQREPYVVSCSA
PHTAADAGRIRAELVPALRELAARLGQLAQPTG

Sequences:

>Translated_273_residues
MRTESLPDTESGAGREGDPNFVTALARGLELLRAFRPGDTLLGNQEFVRRTGFPKATVSRLAGTLVALGYLRYDDALGKY
GLDAGVLALGFAYLASSDVVQLARPHMSAFAQRHGVSISLGRRERLDMVYLETIRHDSPAMGGSSGLGVGSRLSMLSSSM
GRAYLAALPAARRERRYDALRTQQPAQWAAEGAAATDAVKAGVREGYAVSLREWHPAIHACAVAFFVPGQREPYVVSCSA
PHTAADAGRIRAELVPALRELAARLGQLAQPTG
>Mature_273_residues
MRTESLPDTESGAGREGDPNFVTALARGLELLRAFRPGDTLLGNQEFVRRTGFPKATVSRLAGTLVALGYLRYDDALGKY
GLDAGVLALGFAYLASSDVVQLARPHMSAFAQRHGVSISLGRRERLDMVYLETIRHDSPAMGGSSGLGVGSRLSMLSSSM
GRAYLAALPAARRERRYDALRTQQPAQWAAEGAAATDAVKAGVREGYAVSLREWHPAIHACAVAFFVPGQREPYVVSCSA
PHTAADAGRIRAELVPALRELAARLGQLAQPTG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29148; Mature: 29148

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTESLPDTESGAGREGDPNFVTALARGLELLRAFRPGDTLLGNQEFVRRTGFPKATVSR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHH
LAGTLVALGYLRYDDALGKYGLDAGVLALGFAYLASSDVVQLARPHMSAFAQRHGVSISL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GRRERLDMVYLETIRHDSPAMGGSSGLGVGSRLSMLSSSMGRAYLAALPAARRERRYDAL
CCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTQQPAQWAAEGAAATDAVKAGVREGYAVSLREWHPAIHACAVAFFVPGQREPYVVSCSA
HCCCCHHHHHHCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
PHTAADAGRIRAELVPALRELAARLGQLAQPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRTESLPDTESGAGREGDPNFVTALARGLELLRAFRPGDTLLGNQEFVRRTGFPKATVSR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHH
LAGTLVALGYLRYDDALGKYGLDAGVLALGFAYLASSDVVQLARPHMSAFAQRHGVSISL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GRRERLDMVYLETIRHDSPAMGGSSGLGVGSRLSMLSSSMGRAYLAALPAARRERRYDAL
CCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTQQPAQWAAEGAAATDAVKAGVREGYAVSLREWHPAIHACAVAFFVPGQREPYVVSCSA
HCCCCHHHHHHCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
PHTAADAGRIRAELVPALRELAARLGQLAQPTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]