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The map label for this gene is ahpC [C]

Identifier: 17545473

GI number: 17545473

Start: 797056

End: 797694

Strand: Direct

Name: ahpC [C]

Synonym: RSc0754

Alternate gene names: 17545473

Gene position: 797056-797694 (Clockwise)

Preceding gene: 17545469

Following gene: 17545476

Centisome position: 21.45

GC content: 61.19

Gene sequence:

>639_bases
ATGTCTCTACGTCTGGGCGATATCGCCCCCGATTTCGAGCAGGATTCCAGCGAAGGCCGCATCCAGTTCCACACGTGGCT
GGGGAACAGCTGGGGCGTGCTTTTCTCGCATCCGGCGGACTTTACGCCGGTGTGCACCACCGAGCTGGGGCTGACCGCCA
AGCTCAAGGACGCGTTTGCCAAGCGCAACGTCAAGGTCATTGCCCTGTCGGTGGATCCGGTCGATTCGCACAAGAAATGG
ATCGACGACATCAATGAGACACAGAACACCCGCGTCAACTTCCCGATCATCGCCGATGCCGACCGCAAGGTCTCGCAGCT
CTACGACATGATCCACCCGAACGCGAGCGAGACGTTCACCGTGCGCTCGCTATTCGTGATCGACCCGAACAAGAAGGTGC
GGCTGACCATCACGTATCCCGCGTCCACGGGGCGCAACTTCGACGAGGTGCTGCGCGTGATCGATTCGCTGCAGCTGACG
GACCACCACAGCGTGGCTACGCCGGGCAACTGGAAGGACGGCGACGACGTCGTCATCGTGCCGTCGCTGAAGGACGAAGA
GGTCATCAAGCAGAAATTCCCGAAGGGCTACAAGGCCGTGCGGCCGTATCTGCGCCTGACGCCGCAGCCCAACAAGTGA

Upstream 100 bases:

>100_bases
GCGCCAAATGACAAAAAGTGATGTTGTTGTGAATTTATAGTCGTTTTGGTTGGATGGCAATCTGGCTATAGTGGTTCCCA
ACATGGGTATGGAGGACACA

Downstream 100 bases:

>100_bases
CCGTCTCCTTGGTAGTGTGATTGCCGTCCGGTGCGTTGCGCCGGGTGTTTTTTTCGTGCGCGCAAACGGTTGGAATGCGT
GCTGCAGGCACAGCCGGCCA

Product: antioxidant oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLGDIAPDFEQDSSEGRIQFHTWLGNSWGVLFSHPADFTPVCTTELGLTAKLKDAFAKRNVKVIALSVDPVDSHKKW
IDDINETQNTRVNFPIIADADRKVSQLYDMIHPNASETFTVRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLT
DHHSVATPGNWKDGDDVVIVPSLKDEEVIKQKFPKGYKAVRPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSLRLGDIAPDFEQDSSEGRIQFHTWLGNSWGVLFSHPADFTPVCTTELGLTAKLKDAFAKRNVKVIALSVDPVDSHKKW
IDDINETQNTRVNFPIIADADRKVSQLYDMIHPNASETFTVRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLT
DHHSVATPGNWKDGDDVVIVPSLKDEEVIKQKFPKGYKAVRPYLRLTPQPNK
>Mature_211_residues
SLRLGDIAPDFEQDSSEGRIQFHTWLGNSWGVLFSHPADFTPVCTTELGLTAKLKDAFAKRNVKVIALSVDPVDSHKKWI
DDINETQNTRVNFPIIADADRKVSQLYDMIHPNASETFTVRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLTD
HHSVATPGNWKDGDDVVIVPSLKDEEVIKQKFPKGYKAVRPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=52.7027027027027, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI32189392, Length=197, Percent_Identity=32.48730964467, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4505591, Length=181, Percent_Identity=30.939226519337, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI32455266, Length=181, Percent_Identity=30.939226519337, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI32455264, Length=181, Percent_Identity=30.939226519337, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5453549, Length=148, Percent_Identity=31.0810810810811, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32483377, Length=140, Percent_Identity=30.7142857142857, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI5802974, Length=151, Percent_Identity=31.1258278145695, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=41.2060301507538, Blast_Score=164, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=156, Percent_Identity=32.6923076923077, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565831, Length=156, Percent_Identity=32.6923076923077, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554494, Length=144, Percent_Identity=30.5555555555556, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=55.188679245283, Blast_Score=226, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6323613, Length=154, Percent_Identity=30.5194805194805, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=156, Percent_Identity=29.4871794871795, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=50.2283105022831, Blast_Score=216, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=50.9708737864078, Blast_Score=196, Evalue=9e-51,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=50.9708737864078, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=50.9708737864078, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17738015, Length=175, Percent_Identity=32, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17157991, Length=159, Percent_Identity=30.8176100628931, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641739, Length=159, Percent_Identity=30.8176100628931, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=26.9430051813472, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656348, Length=176, Percent_Identity=29.5454545454545, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864676, Length=176, Percent_Identity=29.5454545454545, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23957; Mature: 23826

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDIAPDFEQDSSEGRIQFHTWLGNSWGVLFSHPADFTPVCTTELGLTAKLKDAFA
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEECCCCCCHHHHHHHH
KRNVKVIALSVDPVDSHKKWIDDINETQNTRVNFPIIADADRKVSQLYDMIHPNASETFT
HCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLTDHHSVATPGNWKDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
PSLKDEEVIKQKFPKGYKAVRPYLRLTPQPNK
ECCCCHHHHHHHCCCCHHHHCHHEECCCCCCC
>Mature Secondary Structure 
SLRLGDIAPDFEQDSSEGRIQFHTWLGNSWGVLFSHPADFTPVCTTELGLTAKLKDAFA
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEECCCCCCHHHHHHHH
KRNVKVIALSVDPVDSHKKWIDDINETQNTRVNFPIIADADRKVSQLYDMIHPNASETFT
HCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLTDHHSVATPGNWKDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
PSLKDEEVIKQKFPKGYKAVRPYLRLTPQPNK
ECCCCHHHHHHHCCCCHHHHCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]