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The map label for this gene is yegD [H]

Identifier: 17545358

GI number: 17545358

Start: 685976

End: 687229

Strand: Reverse

Name: yegD [H]

Synonym: RSc0639

Alternate gene names: 17545358

Gene position: 687229-685976 (Counterclockwise)

Preceding gene: 17545367

Following gene: 17545354

Centisome position: 18.49

GC content: 66.27

Gene sequence:

>1254_bases
ATGATGTCAAACGCTTGCGGCGTCGATTTCGGCACGTCCAACTCCACCGTCGGCTGGCTGCGCTCGGACGCACCCACCCT
GCTGCCGCTCGAAGACGGCAAGGTTACGCTGCCTTCCGTCATCTTCTTTCACGCCGAAGACCCGCTGGTCAGCTACGGCC
GTGCCGCGCTGACCGACTATCTTGCCGGCTACGAGGGCCGCCTGATGCGCTCGCTCAAGAGCCTGCTCGGCACGTCGATG
ATGGACGAGAGCACCGAGGTCATGGGCCAGGCCATGCCCTTCCGCAAGCTGCTGGCGCATTTCATCGGCGAACTCAAGAG
GCGCGCCGAGCGCGCCGCCGGCCATGAATTCCGCCGCGCCGTGCTGGGCCGCCCGGTGTTCTTCATCGACGAAGATCCCA
AGGCCGACCAGCTCGCCGAAGACACGCTGTCGGAAATCGCGCGCGACGCCGGCTTCGACGAGATCGCCTTCCAGTACGAG
CCCATCGCCGCCGCGTTCGACTACGAGGCCGGCATCAGCGGTGAAGAACTTGTGCTGGTGGCGGACATTGGCGGCGGTAC
GTCGGACTTCTCGCTGGTGCGCCTGTCGCCCGACCGCGCGAAACGCCCTGACCGCCGCGAGGACATCCTCGCCAACGGCG
GCGTTCACATCGGTGGCACCGACTTCGACCGCGCCTTGAGCCTAGCCAACGTGATGCCGCTACTGGGCCTGAACAGCACG
CTGCGCAACGGCAAGGCGATGCCGTCCGGCCAGTATTTCGACCTGGCGAGCTGGCACACCATCAACCACGTGTACACGCG
CAAGGCGTGGGCGGTGGTGATGGACAATTACCGAGATGTCGCCGACACCGAAAAACTCGACCGCCTAATCCGCCTGATCC
GCGAGCGCGCCGGCCACTGGCTGGCCATCCAGGTGGAAGACGCGAAGATCGCGCTGTCGGACGTCCCGGTGGCGGAGATC
GACCTGCAGCGCATCGCGCCCGAGTTGAAGCAGCCCGTCACGCGCGAGGATTTCGACCAGTCGATTGGGAAGCTGGTCGG
CAAGACGGTCTCGACGGTGCAGGCGATGCTGAAGACGGCGGGCGTCGCAGCAGAAACGGTCGATACCATTCTCTTCGCCG
GCGGCTCCAGCGGGGTGCCGTTGCTGCGCGAGCAACTGGCGCAAGTGCTGCCGTCGGCGCGGCGCGTCGAGGGCGACCTG
TTCGGCGGGATCGGTTCTGGCCTGGCGCGCGATGCGGCGCGCAAGTTTAGCTGA

Upstream 100 bases:

>100_bases
GCACAAAGCCACTACAATAGCGCCCCTTCGCCGGTGGCGCCCGCTCCTGATATCCCGTGCAGGCGCATGCCTCCCGCTGC
ACTCGAGAAGCCACAATCCT

Downstream 100 bases:

>100_bases
CGGGCTGAAAGGCTGAGGGACGGCGGGACGTTTCGAGCGTATCGAACCATTCGGGCTGGGATAGCCGATTTTTATCTCCT
TCGCTCCATCCTATCGGAAC

Product: heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MMSNACGVDFGTSNSTVGWLRSDAPTLLPLEDGKVTLPSVIFFHAEDPLVSYGRAALTDYLAGYEGRLMRSLKSLLGTSM
MDESTEVMGQAMPFRKLLAHFIGELKRRAERAAGHEFRRAVLGRPVFFIDEDPKADQLAEDTLSEIARDAGFDEIAFQYE
PIAAAFDYEAGISGEELVLVADIGGGTSDFSLVRLSPDRAKRPDRREDILANGGVHIGGTDFDRALSLANVMPLLGLNST
LRNGKAMPSGQYFDLASWHTINHVYTRKAWAVVMDNYRDVADTEKLDRLIRLIRERAGHWLAIQVEDAKIALSDVPVAEI
DLQRIAPELKQPVTREDFDQSIGKLVGKTVSTVQAMLKTAGVAAETVDTILFAGGSSGVPLLREQLAQVLPSARRVEGDL
FGGIGSGLARDAARKFS

Sequences:

>Translated_417_residues
MMSNACGVDFGTSNSTVGWLRSDAPTLLPLEDGKVTLPSVIFFHAEDPLVSYGRAALTDYLAGYEGRLMRSLKSLLGTSM
MDESTEVMGQAMPFRKLLAHFIGELKRRAERAAGHEFRRAVLGRPVFFIDEDPKADQLAEDTLSEIARDAGFDEIAFQYE
PIAAAFDYEAGISGEELVLVADIGGGTSDFSLVRLSPDRAKRPDRREDILANGGVHIGGTDFDRALSLANVMPLLGLNST
LRNGKAMPSGQYFDLASWHTINHVYTRKAWAVVMDNYRDVADTEKLDRLIRLIRERAGHWLAIQVEDAKIALSDVPVAEI
DLQRIAPELKQPVTREDFDQSIGKLVGKTVSTVQAMLKTAGVAAETVDTILFAGGSSGVPLLREQLAQVLPSARRVEGDL
FGGIGSGLARDAARKFS
>Mature_417_residues
MMSNACGVDFGTSNSTVGWLRSDAPTLLPLEDGKVTLPSVIFFHAEDPLVSYGRAALTDYLAGYEGRLMRSLKSLLGTSM
MDESTEVMGQAMPFRKLLAHFIGELKRRAERAAGHEFRRAVLGRPVFFIDEDPKADQLAEDTLSEIARDAGFDEIAFQYE
PIAAAFDYEAGISGEELVLVADIGGGTSDFSLVRLSPDRAKRPDRREDILANGGVHIGGTDFDRALSLANVMPLLGLNST
LRNGKAMPSGQYFDLASWHTINHVYTRKAWAVVMDNYRDVADTEKLDRLIRLIRERAGHWLAIQVEDAKIALSDVPVAEI
DLQRIAPELKQPVTREDFDQSIGKLVGKTVSTVQAMLKTAGVAAETVDTILFAGGSSGVPLLREQLAQVLPSARRVEGDL
FGGIGSGLARDAARKFS

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=409, Percent_Identity=23.960880195599, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24234688, Length=421, Percent_Identity=22.5653206650831, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI124256496, Length=409, Percent_Identity=23.960880195599, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI34419635, Length=416, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082035, Length=457, Percent_Identity=30.4157549234136, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1786196, Length=416, Percent_Identity=23.5576923076923, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788875, Length=247, Percent_Identity=29.5546558704453, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534015, Length=411, Percent_Identity=26.0340632603406, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534013, Length=411, Percent_Identity=26.0340632603406, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17507981, Length=413, Percent_Identity=25.181598062954, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534771, Length=412, Percent_Identity=23.7864077669903, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17568549, Length=412, Percent_Identity=22.8155339805825, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319314, Length=412, Percent_Identity=24.0291262135922, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323004, Length=412, Percent_Identity=24.0291262135922, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322505, Length=412, Percent_Identity=24.7572815533981, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320805, Length=414, Percent_Identity=23.9130434782609, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322426, Length=420, Percent_Identity=23.5714285714286, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319396, Length=415, Percent_Identity=23.3734939759036, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320950, Length=412, Percent_Identity=22.5728155339806, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641406, Length=431, Percent_Identity=23.4338747099768, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641408, Length=431, Percent_Identity=23.4338747099768, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641402, Length=431, Percent_Identity=23.4338747099768, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641404, Length=431, Percent_Identity=23.4338747099768, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737941, Length=428, Percent_Identity=23.8317757009346, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 45441; Mature: 45441

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNACGVDFGTSNSTVGWLRSDAPTLLPLEDGKVTLPSVIFFHAEDPLVSYGRAALTDY
CCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEECEEEEEECCCCHHHHHHHHHHHH
LAGYEGRLMRSLKSLLGTSMMDESTEVMGQAMPFRKLLAHFIGELKRRAERAAGHEFRRA
HCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGRPVFFIDEDPKADQLAEDTLSEIARDAGFDEIAFQYEPIAAAFDYEAGISGEELVLV
HHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCHHEEECCCCCCCCCCEEEE
ADIGGGTSDFSLVRLSPDRAKRPDRREDILANGGVHIGGTDFDRALSLANVMPLLGLNST
EECCCCCCCCEEEEECCHHCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCHH
LRNGKAMPSGQYFDLASWHTINHVYTRKAWAVVMDNYRDVADTEKLDRLIRLIRERAGHW
HHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
LAIQVEDAKIALSDVPVAEIDLQRIAPELKQPVTREDFDQSIGKLVGKTVSTVQAMLKTA
EEEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAAETVDTILFAGGSSGVPLLREQLAQVLPSARRVEGDLFGGIGSGLARDAARKFS
CCHHHHHHHHEEECCCCCCHHHHHHHHHHCCHHHHHCCHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MMSNACGVDFGTSNSTVGWLRSDAPTLLPLEDGKVTLPSVIFFHAEDPLVSYGRAALTDY
CCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEECEEEEEECCCCHHHHHHHHHHHH
LAGYEGRLMRSLKSLLGTSMMDESTEVMGQAMPFRKLLAHFIGELKRRAERAAGHEFRRA
HCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGRPVFFIDEDPKADQLAEDTLSEIARDAGFDEIAFQYEPIAAAFDYEAGISGEELVLV
HHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCHHEEECCCCCCCCCCEEEE
ADIGGGTSDFSLVRLSPDRAKRPDRREDILANGGVHIGGTDFDRALSLANVMPLLGLNST
EECCCCCCCCEEEEECCHHCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCHH
LRNGKAMPSGQYFDLASWHTINHVYTRKAWAVVMDNYRDVADTEKLDRLIRLIRERAGHW
HHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
LAIQVEDAKIALSDVPVAEIDLQRIAPELKQPVTREDFDQSIGKLVGKTVSTVQAMLKTA
EEEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAAETVDTILFAGGSSGVPLLREQLAQVLPSARRVEGDLFGGIGSGLARDAARKFS
CCHHHHHHHHEEECCCCCCHHHHHHHHHHCCHHHHHCCHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]