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The map label for this gene is iorB [H]

Identifier: 17545346

GI number: 17545346

Start: 674033

End: 676243

Strand: Direct

Name: iorB [H]

Synonym: RSc0627

Alternate gene names: 17545346

Gene position: 674033-676243 (Clockwise)

Preceding gene: 17545345

Following gene: 17545347

Centisome position: 18.14

GC content: 63.86

Gene sequence:

>2211_bases
ATGACGAACAAGACCGCTCATATCGAGAACGCAAGTCGGCGCAACTTCCTGAACGGCGCGATGGGATTGACCCTGGCTAT
TTACCTGCCAGGCGTAGCCGCGGCGACCGGAGCCGGCAAGGCACGAAGTGCGACGGCTCCCGCGCTGGCGTCCTTTGAGC
CGAATGCCTTTGTGCGCGTCGCTGCCGACAGCACCGTGACGGTCATCTCGAAACACATCGAGATGGGGCAAGGCACGTAT
ACCGGGCTTGCCACGATCGTCGCCGAGGAGCTCGATGCTGCCTGGTCCCAGGTGCGGGTAGAGGGTGCCCCGGCCGATGC
GAAACGGTACAACAACCTGAAGTTCGGCCCGTTCCAGGGAACGGGGGGCAGCACCGCCATTGCCAACTCTTGGGAGCAGT
TGCGCCAAGCAGGGGCTACCGCGCGAGCCATGCTGGTTGGCGCCGCGGCCAAGCAGTGGCAAGTTCCCGCAAACGAGATC
CGTGTCGAAGATGGGGTGGTGCTGCACTCGCGCAGTGGGCGTAAAGCCAACTTCGGTCAGCTTGCGCGGGCAGCCGCGCA
ACAGCCCGTGCCGACCGACGTCAAGCTGAAAGACCCGAAGGACTTCAAACTCATCGGCAAGCGCGCACCGCGCAAAGACA
GTGCAGACAAGACCAACGGCAAGGCACGCTTCACGCAGGACGTGCATCTGCCCGGCATGCTGACGGCCATGGTTGCGCAC
CCGCCGCGCTTTGGCGCCAAAGTGAAATCGTTTAACGCGACCCCCGCCAAGGCGGTACAAGGTGTGGTGGACGTGGTGCA
GATCCCGACCGGCGTGGCCGTGCTAGCCAAGGATACCTGGAGCGCCCGTAAGGGTCGCGATGCTTTACAGGTGGAGTGGG
ACGAATCCGCTGCATTCAAGCTGAGCAGCGACGAGATTTTTGCCCGTTACCACGAATTGGCTAAAACGCCGGGCAGCGTG
GCCCGCAAGGAGGGCGACGTCGATGCCGCGTTTACTCAACCCGCACGCGTGCTGCGTGCCGCGTACGATTTTCCCTTTCT
GGCACATGCGGCCATGGAGCCATTGAACTGCGTCGTGCAGCTCAGCCCGAATGCGTGCGAGATCTGGAACGGCGAGCAAT
TCCAGTCGATTGACCAGACTGCCGTGGCTGCGTTGCTCGGTCTGAAGCCGGAGCAGGTCACGCTCCACATGCTCTACGCC
GGCGGCAGCTTCGGCCGGCGCGCCAGCAAGGACGCAGACTACGTGCTCGAAGCCGTGAATGTCGCCAAGGCGAGCAACAG
CCGCGCACCGGTCAAGCTGGTCTGGACACGCGAAGATGACATGCGGGGCGGCTATTACCGTCCGGCGTTTCATCACGCAC
TGGAAGCGGCGTTGGATACGCAAGGGCGTCCGATTGGTTGGCGCCATCGGCTGGTGGGGCAATCCATCGTGGCCGATACG
GTGTTCGGCGGCATGATCAAGGACGGTGTCGACCCGACGTCGGTGGAGGGCGCGGCCAACTTGCCGTATGCCATTCCGGC
CCTGCACGTCGATTTGCACACGCCGCACGATATTCCGGTGCCCTCGCACTGGTGGCGCTCAGTGGGCTCGACCCACACGG
CGTATTCCACCGAAACCTTCATCGATGAGCTGGCCATCGCAGCGGGGCAAGACCCTGTCGCCTTCAGGCTCGCGTTGCTG
CAAAAGCATCCTCGGCATGCCGGGGCATTGAAGCTCGCTGCGGACAAGGCCGGCTGGGGCCAGCCGCTGGTACCTGCCGC
AGATGGCGCCAAGCGGGCGCGCGGTGTGGCCGTGCACGAGTCGTTCGGGACGGTTGTGGCAGAAGTCGCTGAGGTGACGA
TCAAGCCCGATGGCAGCTTTAGCGTCGATCGAGTGGTCTGTGCGGTCGATTGCGGTGTCGTGGTGAATCCGGATGTGGTG
CGTGCGCAGGTGGAGGGCGGCGTCGGTTATGCGCTTTCTGCTGCGTTACACGGTGCGATCACGTTCAAGGACGGTGCGGT
GGAGCAATCCAATTTCCATGACTACGCGCCGATCCGCATCAATGAGATGCCGAAGGTCGAGGTGCACATCGTGCCTTCCG
CCGAACACCCGACCGGCATTGGCGAGCCGGGGGTGCCGCCGCTGGCGCCAGCAGTGGCTAACGCCATTGCCGCCGCTACG
GGCAAGCGGGTGCGCAGTCTGCCGATCCGCCCCGAAGCGTTGACCGCTTGA

Upstream 100 bases:

>100_bases
GCCGCCATGGCGGGCAACATCTGCCGCTGCGCCACTTACGTCCGTATCCGCGCCGCCATTCACGATGCGGCGAAGCGCCT
GGCCTAACTGGAGCGCAGCC

Downstream 100 bases:

>100_bases
TGCAAGGCGTTGATCTACAGGTACTGGCCGCCGCACGGCAATGGGCGGCCGAGGGGCGGCGCTTTGCGCTTGTGACGGTG
GCACGGACCTGGGGGTCGGC

Product: dehydrogenase large chain transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 736; Mature: 735

Protein sequence:

>736_residues
MTNKTAHIENASRRNFLNGAMGLTLAIYLPGVAAATGAGKARSATAPALASFEPNAFVRVAADSTVTVISKHIEMGQGTY
TGLATIVAEELDAAWSQVRVEGAPADAKRYNNLKFGPFQGTGGSTAIANSWEQLRQAGATARAMLVGAAAKQWQVPANEI
RVEDGVVLHSRSGRKANFGQLARAAAQQPVPTDVKLKDPKDFKLIGKRAPRKDSADKTNGKARFTQDVHLPGMLTAMVAH
PPRFGAKVKSFNATPAKAVQGVVDVVQIPTGVAVLAKDTWSARKGRDALQVEWDESAAFKLSSDEIFARYHELAKTPGSV
ARKEGDVDAAFTQPARVLRAAYDFPFLAHAAMEPLNCVVQLSPNACEIWNGEQFQSIDQTAVAALLGLKPEQVTLHMLYA
GGSFGRRASKDADYVLEAVNVAKASNSRAPVKLVWTREDDMRGGYYRPAFHHALEAALDTQGRPIGWRHRLVGQSIVADT
VFGGMIKDGVDPTSVEGAANLPYAIPALHVDLHTPHDIPVPSHWWRSVGSTHTAYSTETFIDELAIAAGQDPVAFRLALL
QKHPRHAGALKLAADKAGWGQPLVPAADGAKRARGVAVHESFGTVVAEVAEVTIKPDGSFSVDRVVCAVDCGVVVNPDVV
RAQVEGGVGYALSAALHGAITFKDGAVEQSNFHDYAPIRINEMPKVEVHIVPSAEHPTGIGEPGVPPLAPAVANAIAAAT
GKRVRSLPIRPEALTA

Sequences:

>Translated_736_residues
MTNKTAHIENASRRNFLNGAMGLTLAIYLPGVAAATGAGKARSATAPALASFEPNAFVRVAADSTVTVISKHIEMGQGTY
TGLATIVAEELDAAWSQVRVEGAPADAKRYNNLKFGPFQGTGGSTAIANSWEQLRQAGATARAMLVGAAAKQWQVPANEI
RVEDGVVLHSRSGRKANFGQLARAAAQQPVPTDVKLKDPKDFKLIGKRAPRKDSADKTNGKARFTQDVHLPGMLTAMVAH
PPRFGAKVKSFNATPAKAVQGVVDVVQIPTGVAVLAKDTWSARKGRDALQVEWDESAAFKLSSDEIFARYHELAKTPGSV
ARKEGDVDAAFTQPARVLRAAYDFPFLAHAAMEPLNCVVQLSPNACEIWNGEQFQSIDQTAVAALLGLKPEQVTLHMLYA
GGSFGRRASKDADYVLEAVNVAKASNSRAPVKLVWTREDDMRGGYYRPAFHHALEAALDTQGRPIGWRHRLVGQSIVADT
VFGGMIKDGVDPTSVEGAANLPYAIPALHVDLHTPHDIPVPSHWWRSVGSTHTAYSTETFIDELAIAAGQDPVAFRLALL
QKHPRHAGALKLAADKAGWGQPLVPAADGAKRARGVAVHESFGTVVAEVAEVTIKPDGSFSVDRVVCAVDCGVVVNPDVV
RAQVEGGVGYALSAALHGAITFKDGAVEQSNFHDYAPIRINEMPKVEVHIVPSAEHPTGIGEPGVPPLAPAVANAIAAAT
GKRVRSLPIRPEALTA
>Mature_735_residues
TNKTAHIENASRRNFLNGAMGLTLAIYLPGVAAATGAGKARSATAPALASFEPNAFVRVAADSTVTVISKHIEMGQGTYT
GLATIVAEELDAAWSQVRVEGAPADAKRYNNLKFGPFQGTGGSTAIANSWEQLRQAGATARAMLVGAAAKQWQVPANEIR
VEDGVVLHSRSGRKANFGQLARAAAQQPVPTDVKLKDPKDFKLIGKRAPRKDSADKTNGKARFTQDVHLPGMLTAMVAHP
PRFGAKVKSFNATPAKAVQGVVDVVQIPTGVAVLAKDTWSARKGRDALQVEWDESAAFKLSSDEIFARYHELAKTPGSVA
RKEGDVDAAFTQPARVLRAAYDFPFLAHAAMEPLNCVVQLSPNACEIWNGEQFQSIDQTAVAALLGLKPEQVTLHMLYAG
GSFGRRASKDADYVLEAVNVAKASNSRAPVKLVWTREDDMRGGYYRPAFHHALEAALDTQGRPIGWRHRLVGQSIVADTV
FGGMIKDGVDPTSVEGAANLPYAIPALHVDLHTPHDIPVPSHWWRSVGSTHTAYSTETFIDELAIAAGQDPVAFRLALLQ
KHPRHAGALKLAADKAGWGQPLVPAADGAKRARGVAVHESFGTVVAEVAEVTIKPDGSFSVDRVVCAVDCGVVVNPDVVR
AQVEGGVGYALSAALHGAITFKDGAVEQSNFHDYAPIRINEMPKVEVHIVPSAEHPTGIGEPGVPPLAPAVANAIAAATG
KRVRSLPIRPEALTA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=121, Percent_Identity=31.404958677686, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 78135; Mature: 78004

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKTAHIENASRRNFLNGAMGLTLAIYLPGVAAATGAGKARSATAPALASFEPNAFVRV
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCEEEE
AADSTVTVISKHIEMGQGTYTGLATIVAEELDAAWSQVRVEGAPADAKRYNNLKFGPFQG
ECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCCCCCCCC
TGGSTAIANSWEQLRQAGATARAMLVGAAAKQWQVPANEIRVEDGVVLHSRSGRKANFGQ
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECCCEEEECCCCCCCCHHH
LARAAAQQPVPTDVKLKDPKDFKLIGKRAPRKDSADKTNGKARFTQDVHLPGMLTAMVAH
HHHHHHCCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHC
PPRFGAKVKSFNATPAKAVQGVVDVVQIPTGVAVLAKDTWSARKGRDALQVEWDESAAFK
CCCCCCEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEE
LSSDEIFARYHELAKTPGSVARKEGDVDAAFTQPARVLRAAYDFPFLAHAAMEPLNCVVQ
ECCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEE
LSPNACEIWNGEQFQSIDQTAVAALLGLKPEQVTLHMLYAGGSFGRRASKDADYVLEAVN
ECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHH
VAKASNSRAPVKLVWTREDDMRGGYYRPAFHHALEAALDTQGRPIGWRHRLVGQSIVADT
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VFGGMIKDGVDPTSVEGAANLPYAIPALHVDLHTPHDIPVPSHWWRSVGSTHTAYSTETF
HHHHHHHCCCCCCCCCCCCCCCEECEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHH
IDELAIAAGQDPVAFRLALLQKHPRHAGALKLAADKAGWGQPLVPAADGAKRARGVAVHE
HHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHCCEEEEH
SFGTVVAEVAEVTIKPDGSFSVDRVVCAVDCGVVVNPDVVRAQVEGGVGYALSAALHGAI
HHHHHHHHHHHEEECCCCCCCHHEEEEEEECCEEECCHHEEEEECCCCCHHHHHHHHEEE
TFKDGAVEQSNFHDYAPIRINEMPKVEVHIVPSAEHPTGIGEPGVPPLAPAVANAIAAAT
EECCCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
GKRVRSLPIRPEALTA
CCHHHCCCCCCHHCCC
>Mature Secondary Structure 
TNKTAHIENASRRNFLNGAMGLTLAIYLPGVAAATGAGKARSATAPALASFEPNAFVRV
CCCCCCCCCCHHHHHHHHHHHEEEEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCEEEE
AADSTVTVISKHIEMGQGTYTGLATIVAEELDAAWSQVRVEGAPADAKRYNNLKFGPFQG
ECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCCCCCCCC
TGGSTAIANSWEQLRQAGATARAMLVGAAAKQWQVPANEIRVEDGVVLHSRSGRKANFGQ
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECCCEEEECCCCCCCCHHH
LARAAAQQPVPTDVKLKDPKDFKLIGKRAPRKDSADKTNGKARFTQDVHLPGMLTAMVAH
HHHHHHCCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHC
PPRFGAKVKSFNATPAKAVQGVVDVVQIPTGVAVLAKDTWSARKGRDALQVEWDESAAFK
CCCCCCEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEE
LSSDEIFARYHELAKTPGSVARKEGDVDAAFTQPARVLRAAYDFPFLAHAAMEPLNCVVQ
ECCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEE
LSPNACEIWNGEQFQSIDQTAVAALLGLKPEQVTLHMLYAGGSFGRRASKDADYVLEAVN
ECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHH
VAKASNSRAPVKLVWTREDDMRGGYYRPAFHHALEAALDTQGRPIGWRHRLVGQSIVADT
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VFGGMIKDGVDPTSVEGAANLPYAIPALHVDLHTPHDIPVPSHWWRSVGSTHTAYSTETF
HHHHHHHCCCCCCCCCCCCCCCEECEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHH
IDELAIAAGQDPVAFRLALLQKHPRHAGALKLAADKAGWGQPLVPAADGAKRARGVAVHE
HHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHCCEEEEH
SFGTVVAEVAEVTIKPDGSFSVDRVVCAVDCGVVVNPDVVRAQVEGGVGYALSAALHGAI
HHHHHHHHHHHEEECCCCCCCHHEEEEEEECCEEECCHHEEEEECCCCCHHHHHHHHEEE
TFKDGAVEQSNFHDYAPIRINEMPKVEVHIVPSAEHPTGIGEPGVPPLAPAVANAIAAAT
EECCCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
GKRVRSLPIRPEALTA
CCHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]