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The map label for this gene is yeiG [H]

Identifier: 17545323

GI number: 17545323

Start: 650519

End: 651388

Strand: Reverse

Name: yeiG [H]

Synonym: RSc0604

Alternate gene names: 17545323

Gene position: 651388-650519 (Counterclockwise)

Preceding gene: 17545324

Following gene: 17545322

Centisome position: 17.53

GC content: 69.77

Gene sequence:

>870_bases
ATGAGCCAATCACCGACACTCGAACTGCTCTCGGAGCACGCCTGCTTCGGCGGCGTGCAGCGCTTTTACCGGCACGCCTC
GGCGGCGATCGGGCTGCCGATGCGCTTCTCGGTCTACCTGCCGCCGCAGGCCCTGGCCGGCGAGCGCTGCCCGGCGCTGG
TCTACCTCGCCGGGCTGACCTGCACCGAAGAGACCTTCCCGATCAAGGCCGGCGCCCAGCGCATCGCCGCGCGCGAGGGG
CTGATCCTGATCGCGCCCGATACCAGTCCGCGCGACGCCAACGTGCCAGGCGAGGCGGACAGCTGGGATTTCGGCGTCGG
CGCCGGCTTCTACCTGGATGCGACGCAGGCGCCGTGGCGCGAGCGCTACCGGATGGAGACCTACATCGTCGAGGAGCTGT
ACCACATTGCGCGGGTCGCCTTCCCGGTGGCGGCGGGGCGCGTCGGCATCTTCGGGCATTCGATGGGCGGGCACGGTGCG
TTGACGCTGGCGCTGCGTCACCGGGAGCGCTTCGCCTCGGTCTCGGCGTTTGCGCCCATTGCGCATCCGTCGGCCTGCCC
CTGGGGCGTGAAAGCGTTCACCGGCTACCTCGGCGAGGACCGCACCGCCTGGGCCGCGCACGACGCCACGCGGCTGATGC
AACTGGCGAACAACCCGTTTCCTGGCGGCATCCTGATCGATCAAGGCGAGGCGGACACCTTCCTCGCCGAGCAGCTGTAC
CCCGATGACTTCGCCGCCGCGTGCGAGGCGGCCGGGCAGCCACTGCAACTGCGCCGCCATCCCGGCTACGACCACGGCTA
TTACTTCATCCAGACCTTCATCGAAGACCACCTGCGGCACCACGCGGCACAACTGCGCGGCGTCGGCTAG

Upstream 100 bases:

>100_bases
ATCACGCACACGCTGCCGCTCGAGCGCATCAACGAGGGCTTCGACCTGATGAAGCGCGGCGAGTCGATCCGCTCGGTGGT
CCTGTACTGAGGAGGGCGCG

Downstream 100 bases:

>100_bases
CGAGCGGGGGCGCCGCGCTCAGCGGTTGCCCCAGTCGCCTGTGGTCGCGCCGGTGCCGGGGGCCCCCACCCTGCCATCGC
CGGGCGCACCGACCCGCCCA

Product: hydrolase oxidoreductase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSQSPTLELLSEHACFGGVQRFYRHASAAIGLPMRFSVYLPPQALAGERCPALVYLAGLTCTEETFPIKAGAQRIAAREG
LILIAPDTSPRDANVPGEADSWDFGVGAGFYLDATQAPWRERYRMETYIVEELYHIARVAFPVAAGRVGIFGHSMGGHGA
LTLALRHRERFASVSAFAPIAHPSACPWGVKAFTGYLGEDRTAWAAHDATRLMQLANNPFPGGILIDQGEADTFLAEQLY
PDDFAAACEAAGQPLQLRRHPGYDHGYYFIQTFIEDHLRHHAAQLRGVG

Sequences:

>Translated_289_residues
MSQSPTLELLSEHACFGGVQRFYRHASAAIGLPMRFSVYLPPQALAGERCPALVYLAGLTCTEETFPIKAGAQRIAAREG
LILIAPDTSPRDANVPGEADSWDFGVGAGFYLDATQAPWRERYRMETYIVEELYHIARVAFPVAAGRVGIFGHSMGGHGA
LTLALRHRERFASVSAFAPIAHPSACPWGVKAFTGYLGEDRTAWAAHDATRLMQLANNPFPGGILIDQGEADTFLAEQLY
PDDFAAACEAAGQPLQLRRHPGYDHGYYFIQTFIEDHLRHHAAQLRGVG
>Mature_288_residues
SQSPTLELLSEHACFGGVQRFYRHASAAIGLPMRFSVYLPPQALAGERCPALVYLAGLTCTEETFPIKAGAQRIAAREGL
ILIAPDTSPRDANVPGEADSWDFGVGAGFYLDATQAPWRERYRMETYIVEELYHIARVAFPVAAGRVGIFGHSMGGHGAL
TLALRHRERFASVSAFAPIAHPSACPWGVKAFTGYLGEDRTAWAAHDATRLMQLANNPFPGGILIDQGEADTFLAEQLYP
DDFAAACEAAGQPLQLRRHPGYDHGYYFIQTFIEDHLRHHAAQLRGVG

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=284, Percent_Identity=53.5211267605634, Blast_Score=323, Evalue=1e-88,
Organism=Escherichia coli, GI1788477, Length=279, Percent_Identity=50.8960573476703, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1786551, Length=280, Percent_Identity=46.7857142857143, Blast_Score=263, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI17510185, Length=283, Percent_Identity=46.643109540636, Blast_Score=259, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6322393, Length=296, Percent_Identity=38.1756756756757, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI45551932, Length=287, Percent_Identity=49.1289198606272, Blast_Score=287, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24648347, Length=282, Percent_Identity=49.645390070922, Blast_Score=283, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31583; Mature: 31452

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSPTLELLSEHACFGGVQRFYRHASAAIGLPMRFSVYLPPQALAGERCPALVYLAGLT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHCCCCCCEEEEEECCE
CTEETFPIKAGAQRIAAREGLILIAPDTSPRDANVPGEADSWDFGVGAGFYLDATQAPWR
ECCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHH
ERYRMETYIVEELYHIARVAFPVAAGRVGIFGHSMGGHGALTLALRHRERFASVSAFAPI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHCCC
AHPSACPWGVKAFTGYLGEDRTAWAAHDATRLMQLANNPFPGGILIDQGEADTFLAEQLY
CCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHCC
PDDFAAACEAAGQPLQLRRHPGYDHGYYFIQTFIEDHLRHHAAQLRGVG
CCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQSPTLELLSEHACFGGVQRFYRHASAAIGLPMRFSVYLPPQALAGERCPALVYLAGLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHCCCCCCEEEEEECCE
CTEETFPIKAGAQRIAAREGLILIAPDTSPRDANVPGEADSWDFGVGAGFYLDATQAPWR
ECCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHH
ERYRMETYIVEELYHIARVAFPVAAGRVGIFGHSMGGHGALTLALRHRERFASVSAFAPI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHCCC
AHPSACPWGVKAFTGYLGEDRTAWAAHDATRLMQLANNPFPGGILIDQGEADTFLAEQLY
CCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHCC
PDDFAAACEAAGQPLQLRRHPGYDHGYYFIQTFIEDHLRHHAAQLRGVG
CCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA