Click here to switch to the map view.

The map label for this gene is gmhB [H]

Identifier: 17545242

GI number: 17545242

Start: 560668

End: 561267

Strand: Reverse

Name: gmhB [H]

Synonym: RSc0523

Alternate gene names: 17545242

Gene position: 561267-560668 (Counterclockwise)

Preceding gene: 17545243

Following gene: 17545241

Centisome position: 15.1

GC content: 70.5

Gene sequence:

>600_bases
ATGCCGCACATACCGAAGCTCGTGATCCTGGACCGCGATGGCGTCATCAACCTCGACAGCGACCAGTTCATCAAGTCGCC
CGACGAGTGGATCGCCATCGAGGGCAGCCTGGAGGCGATCGCCGAACTGAACCAGGCCGGCTACCAGGTGGTGGTCGCCA
CCAACCAGTCGGGCATCGGGCGCGGACTGTTCGAGGCCGCCGCGCTCAACGCCATGCACGAGAAGATGTACAAGGCGCTG
GCGTCGCAGGGCGGCCGCGTCGATGCGGTCTTCTTCTGCCCGCACACCGCCGCCGAAGGGTGCGACTGCCGCAAGCCCAA
GGCCGGCATGTTCCGTGAAATCGCCCGCCGCTTCGACGTCGACCTCGCCGGCGTGCCGGTGGTCGGCGACTCGCTGCGCG
ACCTGCAGGCCGGCGCGGAAGTCGGCGCCGTGCCGCACCTCGTGCTGACCGGCAAGGGCGCCAAGACGCTGCAGGCCGGC
AACCTGCCGCCCGGCACGCACGTCCACCAGGACCTGCGCGCCTTCGCCCGCGCGCTGCTCTCGCCCGCACATCATCCTCC
CGGCGCGCCGTCGCGCGCGCCGACCGAACCCGCACCATGA

Upstream 100 bases:

>100_bases
GCGACAACCGCCTGGCCCTGCTGGGCGAGCTGCACGGCCTGATGAACCGCGTGGCCGACATCTCCAAGCTGGCAGCGTAA
GCCCTGCCCCGGAGCCCGAC

Downstream 100 bases:

>100_bases
CTTTTGTCCGTTCGCTGCTGTACCTGAGTTTCCTGATCGTCTGGACACCGTTCTATGCGGTGGCCTGCTTCATCGCCTTT
CCGTTCATGAACCCGCATCG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPHIPKLVILDRDGVINLDSDQFIKSPDEWIAIEGSLEAIAELNQAGYQVVVATNQSGIGRGLFEAAALNAMHEKMYKAL
ASQGGRVDAVFFCPHTAAEGCDCRKPKAGMFREIARRFDVDLAGVPVVGDSLRDLQAGAEVGAVPHLVLTGKGAKTLQAG
NLPPGTHVHQDLRAFARALLSPAHHPPGAPSRAPTEPAP

Sequences:

>Translated_199_residues
MPHIPKLVILDRDGVINLDSDQFIKSPDEWIAIEGSLEAIAELNQAGYQVVVATNQSGIGRGLFEAAALNAMHEKMYKAL
ASQGGRVDAVFFCPHTAAEGCDCRKPKAGMFREIARRFDVDLAGVPVVGDSLRDLQAGAEVGAVPHLVLTGKGAKTLQAG
NLPPGTHVHQDLRAFARALLSPAHHPPGAPSRAPTEPAP
>Mature_198_residues
PHIPKLVILDRDGVINLDSDQFIKSPDEWIAIEGSLEAIAELNQAGYQVVVATNQSGIGRGLFEAAALNAMHEKMYKALA
SQGGRVDAVFFCPHTAAEGCDCRKPKAGMFREIARRFDVDLAGVPVVGDSLRDLQAGAEVGAVPHLVLTGKGAKTLQAGN
LPPGTHVHQDLRAFARALLSPAHHPPGAPSRAPTEPAP

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=154, Percent_Identity=38.961038961039, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082027, Length=144, Percent_Identity=34.0277777777778, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 21048; Mature: 20917

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHIPKLVILDRDGVINLDSDQFIKSPDEWIAIEGSLEAIAELNQAGYQVVVATNQSGIG
CCCCCEEEEECCCCEEECCCHHHHCCCCCEEEECCCHHHHHHHHHCCEEEEEEECCCCCC
RGLFEAAALNAMHEKMYKALASQGGRVDAVFFCPHTAAEGCDCRKPKAGMFREIARRFDV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
DLAGVPVVGDSLRDLQAGAEVGAVPHLVLTGKGAKTLQAGNLPPGTHVHQDLRAFARALL
CCCCCCEECCHHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHH
SPAHHPPGAPSRAPTEPAP
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PHIPKLVILDRDGVINLDSDQFIKSPDEWIAIEGSLEAIAELNQAGYQVVVATNQSGIG
CCCCEEEEECCCCEEECCCHHHHCCCCCEEEECCCHHHHHHHHHCCEEEEEEECCCCCC
RGLFEAAALNAMHEKMYKALASQGGRVDAVFFCPHTAAEGCDCRKPKAGMFREIARRFDV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
DLAGVPVVGDSLRDLQAGAEVGAVPHLVLTGKGAKTLQAGNLPPGTHVHQDLRAFARALL
CCCCCCEECCHHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHH
SPAHHPPGAPSRAPTEPAP
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]