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The map label for this gene is gpmB [H]

Identifier: 17545218

GI number: 17545218

Start: 533504

End: 534187

Strand: Direct

Name: gpmB [H]

Synonym: RSc0499

Alternate gene names: 17545218

Gene position: 533504-534187 (Clockwise)

Preceding gene: 17545217

Following gene: 17545229

Centisome position: 14.36

GC content: 71.05

Gene sequence:

>684_bases
ATGGCACGCACCGCCGCCATGCCCATGCCGATGCCGCAGATCACCCACATCGTGCTGGTGCGGCACGGCGAGACCGACTG
GAACCGCGAGCGCCGGCTCCAGGGCCAGCTCGACGTGCCGCTCAATGCGCAAGGGCGCGAACAGGCCGCGCAGCTGGGCC
GGGCGCTGGCGCGCGAGCCGTTCGATGCGATCTATGCCAGCGATCTGTCGCGCGCCAGGGAGACGGCGCAGGCATTGGCC
GGCGAGGTCGGCAAGGCTGTGCGCGATGACACCGGCCTGCGCGAACGCTGCTACGGCGGGTTCGAAGGGCTGACCTATGC
AGAGGTGGCCGAGCGCCATCCGGCGGAATTCGAGGCGTGGCAGAGCCGCGTGCCGGAATTCGCCCCGCCCGGCGGCGGCG
AGACGCTGGCCGGGTTCCACGCGCGCGCGGTGGATGCGGCGCTGCGGCTGATTCGCCGCCATCCGGGCGAGCGCATCGCG
CTGGTTAGCCATGGCGGTGTGCTCGATTGCCTGTACCGGCACGCCAACGCCATGACGCTCACCGAGCCGCGCCAGCACGC
GCTGCGCAATGCCAGCATCAACCGGCTGTCGTCCGACGGGCACCAGCTGACCGTGCTGCAGTGGGGGGATGTCGCGCACC
TGGACCTGCTGGTGCTCGACGAAGTGGATCGGCGCGTACCGTAG

Upstream 100 bases:

>100_bases
ACGCGCCGATTCCCGTCGAATGTGTCGAAGGCCACGCGCTGGCCGAGGCGTCCGTGACCGGCACCTGCATGCGCAACCCG
AGCCCTGCGGAGAAGCCCTG

Downstream 100 bases:

>100_bases
GGTGGCCTCAGACCCGCGGCCGGGGCGGCATGCAGCCGATGCGCCGATGCTGCGGCTGATCGGCTAGGCGTTGTTGTCCC
ACAGGTCGCGCGCCGGACCG

Product: phosphoglycerate mutase 2 protein

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MARTAAMPMPMPQITHIVLVRHGETDWNRERRLQGQLDVPLNAQGREQAAQLGRALAREPFDAIYASDLSRARETAQALA
GEVGKAVRDDTGLRERCYGGFEGLTYAEVAERHPAEFEAWQSRVPEFAPPGGGETLAGFHARAVDAALRLIRRHPGERIA
LVSHGGVLDCLYRHANAMTLTEPRQHALRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP

Sequences:

>Translated_227_residues
MARTAAMPMPMPQITHIVLVRHGETDWNRERRLQGQLDVPLNAQGREQAAQLGRALAREPFDAIYASDLSRARETAQALA
GEVGKAVRDDTGLRERCYGGFEGLTYAEVAERHPAEFEAWQSRVPEFAPPGGGETLAGFHARAVDAALRLIRRHPGERIA
LVSHGGVLDCLYRHANAMTLTEPRQHALRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP
>Mature_226_residues
ARTAAMPMPMPQITHIVLVRHGETDWNRERRLQGQLDVPLNAQGREQAAQLGRALAREPFDAIYASDLSRARETAQALAG
EVGKAVRDDTGLRERCYGGFEGLTYAEVAERHPAEFEAWQSRVPEFAPPGGGETLAGFHARAVDAALRLIRRHPGERIAL
VSHGGVLDCLYRHANAMTLTEPRQHALRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=135, Percent_Identity=38.5185185185185, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI50593010, Length=122, Percent_Identity=37.7049180327869, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1790856, Length=222, Percent_Identity=36.9369369369369, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1786970, Length=200, Percent_Identity=31.5, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786857, Length=153, Percent_Identity=31.3725490196078, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324857, Length=218, Percent_Identity=28.8990825688073, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322697, Length=125, Percent_Identity=36, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24646216, Length=120, Percent_Identity=37.5, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571815, Length=127, Percent_Identity=33.8582677165354, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648979, Length=127, Percent_Identity=33.8582677165354, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571817, Length=127, Percent_Identity=33.8582677165354, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25128; Mature: 24997

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTAAMPMPMPQITHIVLVRHGETDWNRERRLQGQLDVPLNAQGREQAAQLGRALAREP
CCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCH
FDAIYASDLSRARETAQALAGEVGKAVRDDTGLRERCYGGFEGLTYAEVAERHPAEFEAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHCCCCHHHHH
QSRVPEFAPPGGGETLAGFHARAVDAALRLIRRHPGERIALVSHGGVLDCLYRHANAMTL
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEE
TEPRQHALRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARTAAMPMPMPQITHIVLVRHGETDWNRERRLQGQLDVPLNAQGREQAAQLGRALAREP
CCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCH
FDAIYASDLSRARETAQALAGEVGKAVRDDTGLRERCYGGFEGLTYAEVAERHPAEFEAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHCCCCHHHHH
QSRVPEFAPPGGGETLAGFHARAVDAALRLIRRHPGERIALVSHGGVLDCLYRHANAMTL
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEE
TEPRQHALRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA