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The map label for this gene is 17545169

Identifier: 17545169

GI number: 17545169

Start: 478618

End: 479541

Strand: Direct

Name: 17545169

Synonym: RSc0450

Alternate gene names: NA

Gene position: 478618-479541 (Clockwise)

Preceding gene: 17545165

Following gene: 17545171

Centisome position: 12.88

GC content: 67.1

Gene sequence:

>924_bases
ATGGACATCCGGTCGTTCCTTTCCCGGCGCACGCGCCGCGGGCGCAAGCTCTGGTCCGGCACCCAGCACGTGATTGCCCA
CGGCATGCCGCCGCTCGGCTGGCGCGACATCTACCACCGCGCGCTGGAGGTGAACTGGCCGACGTTCTTCGCGCTGCTCG
CCGGGCTGTTCTTCATGCTGAACACCGTCTTCGCCGGGCTGTATTCGCTCGGCACGGCGTCCATCGCCAACCAGTCGCCG
CCGGGCTTCGTCGGGGCGTTCTTCTTCAGCGTGGAGACGCTCGCCACCGTCGGCTACGGCGACATGCACCCGCAGACCCT
CTACGCGCACTGCATCGCCACGCTGGAGATCTTCGTCGGCATGTCGGGCATCGCCCTGGCCACGGGGCTGGTGTTCGCGC
GCTTCTCGCGGCCGCGCGCCAAGATCATGTTCGTGCGCAATCCGATCGTGCGCACGCTCAACGGCAAGCCGACGCTGATG
GTGCGTGCCGCCAACGCACGCCAGAACGTGATCGCCGAGGCCACGGCCAAGCTGCGCCTGCTGCAGGACGAACGCTCGCC
CGAGGGCTACACGCTCTACAAGATTCGCGATCTCACGCTGGTGCGCAGCGAGCATCCGATCTTCCTGCTCGGCTGGATCC
TGATGCACGTGATCGACGAGACGAGTCCGCTCTTCGGCGCTACCGCCGCGTCGCTCGCCGCCGGCGATGCCTTGCTGCTG
CTCACCATCGGGGGCTCCGACGAGACCGCCGCCCAGACCTTGCTGGCACGCCATTCCTGGCGGCACGACGAGATTCGCTG
GGGGCATCGCTATGTCGACCTGATGCACGACGAAGGCAACGTCACGCATGTCGACTACGCGAACTTTCACGAGACCGTGC
CGGTGGACGAGCCGGCCGCTGGCGCATCATCCGACCAGGCTTGA

Upstream 100 bases:

>100_bases
ATCACGCGGCGTCTTGTGCCAGGGCCGGACCGGTCGGTACACTGCCCCGGCCGCCCGGGGCCCGGGCACAACCCCTGTAC
CTTTCGGGAGGAGGGCAGCG

Downstream 100 bases:

>100_bases
GCGGCGCGGGACTACACGGCCTTCGGCTGCACTGCGCGCCGTTCCATGACCGCCGCGATCACCCAGGCTTGCGCCGCCGC
GATGACGGCCCAGAAACCCA

Product: ATP-sensitive inward rectifier potassium channel related transmembrane protein

Products: NA

Alternate protein names: Ion Transport 2 Domain-Containing Protein; K+ Channel Inward Rectifier; Inward Rectifier Potassium Channel; Inward Rectifier Potassium Channel Protein; Inward Rectifier Potassium Channel Superfamily; TrkA-N Family Protein; K+ Channel Inward Rectifier Protein; ATP-Sensitive Potassium Transporter; Potassium Channel Protein; Inward Rectifier Potassium Channel Irk; K+ Channel Protein; ATP-Sensitive Potassium Channel Protein; Ion Transport 2 Domain Protein; ATP-Sensitive Inward Rectifier Potassium Channel

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDIRSFLSRRTRRGRKLWSGTQHVIAHGMPPLGWRDIYHRALEVNWPTFFALLAGLFFMLNTVFAGLYSLGTASIANQSP
PGFVGAFFFSVETLATVGYGDMHPQTLYAHCIATLEIFVGMSGIALATGLVFARFSRPRAKIMFVRNPIVRTLNGKPTLM
VRAANARQNVIAEATAKLRLLQDERSPEGYTLYKIRDLTLVRSEHPIFLLGWILMHVIDETSPLFGATAASLAAGDALLL
LTIGGSDETAAQTLLARHSWRHDEIRWGHRYVDLMHDEGNVTHVDYANFHETVPVDEPAAGASSDQA

Sequences:

>Translated_307_residues
MDIRSFLSRRTRRGRKLWSGTQHVIAHGMPPLGWRDIYHRALEVNWPTFFALLAGLFFMLNTVFAGLYSLGTASIANQSP
PGFVGAFFFSVETLATVGYGDMHPQTLYAHCIATLEIFVGMSGIALATGLVFARFSRPRAKIMFVRNPIVRTLNGKPTLM
VRAANARQNVIAEATAKLRLLQDERSPEGYTLYKIRDLTLVRSEHPIFLLGWILMHVIDETSPLFGATAASLAAGDALLL
LTIGGSDETAAQTLLARHSWRHDEIRWGHRYVDLMHDEGNVTHVDYANFHETVPVDEPAAGASSDQA
>Mature_307_residues
MDIRSFLSRRTRRGRKLWSGTQHVIAHGMPPLGWRDIYHRALEVNWPTFFALLAGLFFMLNTVFAGLYSLGTASIANQSP
PGFVGAFFFSVETLATVGYGDMHPQTLYAHCIATLEIFVGMSGIALATGLVFARFSRPRAKIMFVRNPIVRTLNGKPTLM
VRAANARQNVIAEATAKLRLLQDERSPEGYTLYKIRDLTLVRSEHPIFLLGWILMHVIDETSPLFGATAASLAAGDALLL
LTIGGSDETAAQTLLARHSWRHDEIRWGHRYVDLMHDEGNVTHVDYANFHETVPVDEPAAGASSDQA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4826802, Length=231, Percent_Identity=31.1688311688312, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI23110982, Length=236, Percent_Identity=31.7796610169492, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI303227939, Length=233, Percent_Identity=31.3304721030043, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4826798, Length=235, Percent_Identity=32.7659574468085, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI23110984, Length=235, Percent_Identity=32.7659574468085, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI4504839, Length=251, Percent_Identity=29.4820717131474, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI25121970, Length=232, Percent_Identity=30.6034482758621, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4504835, Length=298, Percent_Identity=27.5167785234899, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI24497471, Length=240, Percent_Identity=30.8333333333333, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI148539892, Length=240, Percent_Identity=30.8333333333333, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI24497467, Length=240, Percent_Identity=30.8333333333333, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI24497473, Length=240, Percent_Identity=30.8333333333333, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI4504837, Length=240, Percent_Identity=30.8333333333333, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI25777635, Length=280, Percent_Identity=28.2142857142857, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI7019439, Length=280, Percent_Identity=28.2142857142857, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI25121966, Length=299, Percent_Identity=27.0903010033445, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4504843, Length=235, Percent_Identity=28.0851063829787, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI24797141, Length=235, Percent_Identity=27.2340425531915, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI239751249, Length=297, Percent_Identity=28.6195286195286, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310117729, Length=297, Percent_Identity=28.6195286195286, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI62388888, Length=291, Percent_Identity=27.4914089347079, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI261399884, Length=245, Percent_Identity=30.2040816326531, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI25777640, Length=296, Percent_Identity=25.3378378378378, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI25777638, Length=296, Percent_Identity=25.3378378378378, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI21361127, Length=296, Percent_Identity=25.3378378378378, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI8923823, Length=227, Percent_Identity=27.7533039647577, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI25777630, Length=227, Percent_Identity=27.7533039647577, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI25777628, Length=227, Percent_Identity=27.7533039647577, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI156119627, Length=283, Percent_Identity=24.7349823321555, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI289547204, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71993162, Length=285, Percent_Identity=29.1228070175439, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17568583, Length=327, Percent_Identity=27.5229357798165, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17568581, Length=293, Percent_Identity=25.938566552901, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI62484243, Length=320, Percent_Identity=28.75, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24649234, Length=338, Percent_Identity=25.7396449704142, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161078534, Length=337, Percent_Identity=25.8160237388724, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281362353, Length=338, Percent_Identity=25.7396449704142, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221476063, Length=294, Percent_Identity=29.2517006802721, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281362366, Length=235, Percent_Identity=27.2340425531915, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24649327, Length=235, Percent_Identity=27.2340425531915, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24649329, Length=235, Percent_Identity=27.2340425531915, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34033; Mature: 34033

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRSFLSRRTRRGRKLWSGTQHVIAHGMPPLGWRDIYHRALEVNWPTFFALLAGLFFML
CCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
NTVFAGLYSLGTASIANQSPPGFVGAFFFSVETLATVGYGDMHPQTLYAHCIATLEIFVG
HHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
MSGIALATGLVFARFSRPRAKIMFVRNPIVRTLNGKPTLMVRAANARQNVIAEATAKLRL
CCHHHHHHHHHHHHCCCCCEEEEEEECCHHEECCCCCEEEEEECCCHHHHHHHHHHHHHH
LQDERSPEGYTLYKIRDLTLVRSEHPIFLLGWILMHVIDETSPLFGATAASLAAGDALLL
HHHCCCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEE
LTIGGSDETAAQTLLARHSWRHDEIRWGHRYVDLMHDEGNVTHVDYANFHETVPVDEPAA
EEECCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCC
GASSDQA
CCCCCCC
>Mature Secondary Structure
MDIRSFLSRRTRRGRKLWSGTQHVIAHGMPPLGWRDIYHRALEVNWPTFFALLAGLFFML
CCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
NTVFAGLYSLGTASIANQSPPGFVGAFFFSVETLATVGYGDMHPQTLYAHCIATLEIFVG
HHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
MSGIALATGLVFARFSRPRAKIMFVRNPIVRTLNGKPTLMVRAANARQNVIAEATAKLRL
CCHHHHHHHHHHHHCCCCCEEEEEEECCHHEECCCCCEEEEEECCCHHHHHHHHHHHHHH
LQDERSPEGYTLYKIRDLTLVRSEHPIFLLGWILMHVIDETSPLFGATAASLAAGDALLL
HHHCCCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEE
LTIGGSDETAAQTLLARHSWRHDEIRWGHRYVDLMHDEGNVTHVDYANFHETVPVDEPAA
EEECCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCC
GASSDQA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA