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The map label for this gene is coxC [H]

Identifier: 17545086

GI number: 17545086

Start: 395834

End: 396694

Strand: Direct

Name: coxC [H]

Synonym: RSc0367

Alternate gene names: 17545086

Gene position: 395834-396694 (Clockwise)

Preceding gene: 17545085

Following gene: 17545088

Centisome position: 10.65

GC content: 65.85

Gene sequence:

>861_bases
ATGAGTGCGAATCGAGCGAACGCTCCGTACTACTTCGTGCCAGGGCCCTCGCGGCATCCGATTTCGGCGAGCATCGGCCT
GCTGATCGTGCTGCTCAGCGCGGCGGCGTGGGTCAACGCGCAGCCGTGGGCGCCGTGGACCTTCCTGATCGGCCTGCTGT
GGTTCCTGTTCGTGCTGCGCGCGTGGTTCGCCGACGCCATCTCCGAGTCCGAGGGCGGCCAGTACGGCGACCGCGTGGAC
GCCTCGTTCCGTTGGTCGATGAGCTGGTTCATCTTCTCGGAAGTGATGTTCTTCGCCGCCTTCTTCGGCGCGCTGTTCTA
TGCCCGCACCATTGCCATGCCGTGGCTGGGCGACCTGAACAACAAGCTGCTGTGGCCCGACTTCAACGCGCTGTGGCCGA
ACGCCGGCCCGGCCGGCACGGTGCCGCCGTTCACGACGATGGGTCCGTGGCCGATCCCGACCATCAACACCGCGCTGCTG
CTCACTTCCGGCGTGACGCTGACCTGGGCGCACCACGCGCTGCGCGAGGGCAAGCGGGCACAGGTCATCCAGGGCATGCT
GCTGACGGTCATCCTGGGCGCCACGTTCATGTGCCTGCAGGCGTACGAATACATCCACGCCTACCACGAGCTGAACCTGA
AGCTGACCTCGGGCATCTACGGCTCGACCTTCTTCATGCTGACCGGCTTCCACGGCTTCCACGTGACGATGGGCGCGATC
ATGCTGGCGGTGGTGCTGGGCCGCGTGATCAAGGGGCACTTCACGCCGGAGCACCACTTCGCGTTCGAGGGCGCCGCCTG
GTACTGGCACTTCGTGGACGTGGTCTGGCTCGGCCTGTACGTGGTGGTGTACTGGCTGTAG

Upstream 100 bases:

>100_bases
CGTGCGGTGGTGGGTTGAGGAGGCGGTCCGGCGCGTCGCGCATCGCCGCGGCGCCGGGCGGATCGAGTGTGGTTCCAATA
AGAGAGCTGGAGAACAAGAG

Downstream 100 bases:

>100_bases
GCGGGCCCGGGGGCGGTCGCGCATGCGTCGCCCCTGTCGCATCGATGCCGCAGACGGGAAGCCGCTGCGGCGTTTTCATT
TTTATCGGCCGAGCTGGATG

Product: cytochrome C oxidase subunit III transmembrane protein

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSANRANAPYYFVPGPSRHPISASIGLLIVLLSAAAWVNAQPWAPWTFLIGLLWFLFVLRAWFADAISESEGGQYGDRVD
ASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKLLWPDFNALWPNAGPAGTVPPFTTMGPWPIPTINTALL
LTSGVTLTWAHHALREGKRAQVIQGMLLTVILGATFMCLQAYEYIHAYHELNLKLTSGIYGSTFFMLTGFHGFHVTMGAI
MLAVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Sequences:

>Translated_286_residues
MSANRANAPYYFVPGPSRHPISASIGLLIVLLSAAAWVNAQPWAPWTFLIGLLWFLFVLRAWFADAISESEGGQYGDRVD
ASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKLLWPDFNALWPNAGPAGTVPPFTTMGPWPIPTINTALL
LTSGVTLTWAHHALREGKRAQVIQGMLLTVILGATFMCLQAYEYIHAYHELNLKLTSGIYGSTFFMLTGFHGFHVTMGAI
MLAVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
>Mature_285_residues
SANRANAPYYFVPGPSRHPISASIGLLIVLLSAAAWVNAQPWAPWTFLIGLLWFLFVLRAWFADAISESEGGQYGDRVDA
SFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKLLWPDFNALWPNAGPAGTVPPFTTMGPWPIPTINTALLL
TSGVTLTWAHHALREGKRAQVIQGMLLTVILGATFMCLQAYEYIHAYHELNLKLTSGIYGSTFFMLTGFHGFHVTMGAIM
LAVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=225, Percent_Identity=45.3333333333333, Blast_Score=168, Evalue=5e-42,
Organism=Escherichia coli, GI1786633, Length=151, Percent_Identity=33.7748344370861, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6226542, Length=227, Percent_Identity=35.2422907488987, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32179; Mature: 32048

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANRANAPYYFVPGPSRHPISASIGLLIVLLSAAAWVNAQPWAPWTFLIGLLWFLFVLR
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AWFADAISESEGGQYGDRVDASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLN
HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NKLLWPDFNALWPNAGPAGTVPPFTTMGPWPIPTINTALLLTSGVTLTWAHHALREGKRA
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHH
QVIQGMLLTVILGATFMCLQAYEYIHAYHELNLKLTSGIYGSTFFMLTGFHGFHVTMGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCHHHHHHHHH
MLAVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SANRANAPYYFVPGPSRHPISASIGLLIVLLSAAAWVNAQPWAPWTFLIGLLWFLFVLR
CCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AWFADAISESEGGQYGDRVDASFRWSMSWFIFSEVMFFAAFFGALFYARTIAMPWLGDLN
HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NKLLWPDFNALWPNAGPAGTVPPFTTMGPWPIPTINTALLLTSGVTLTWAHHALREGKRA
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHH
QVIQGMLLTVILGATFMCLQAYEYIHAYHELNLKLTSGIYGSTFFMLTGFHGFHVTMGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCHHHHHHHHH
MLAVVLGRVIKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]