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The map label for this gene is gpmA [H]

Identifier: 17545072

GI number: 17545072

Start: 385285

End: 386088

Strand: Reverse

Name: gpmA [H]

Synonym: RSc0353

Alternate gene names: 17545072

Gene position: 386088-385285 (Counterclockwise)

Preceding gene: 17545077

Following gene: 17545071

Centisome position: 10.39

GC content: 66.79

Gene sequence:

>804_bases
ATGACGCAGCGCGTCCCGGCCACCGCGCAGGTTTTCTCACTTCTCATCATGGCAGTCATGCACAAGCTCGTCCTCATCCG
CCACGGCGAATCGACGTGGAACCTCGAAAACCGCTTCACCGGCTGGGTCGACGTCGACCTGACCGACACCGGCATCGCCC
AGGCCCGCCAGGGCGGCCGCCTGCTGCGCGAAGCCGGCTTCACCTTCGACCTGGCCTACACCTCGGTGCTCAAGCGCGCC
ATCCGCACACTGTGGCACGTGCAGGATGAAATGGACCTGATGTGGATCCCGACCCGCACCGAATGGCGCCTGAACGAGCG
CCACTATGGCGGCCTGTCGGGTCTGAACAAGGCCGAGACCGCCGCCCAGTACGGCGACCAGCAGGTGCTGGTCTGGCGCC
GCAGCTACGACACGCCGCCGCCCGCGCTGGAAGCCGGCGACGAGCGCGACGCGTATGGCAACCCGCGCTATGCGGGCCTG
CCGCGCGAACAGGTGCCGCTCACCGAATGCCTGAAGGACACCGTGGCGCGCGTGCTGCCGCTGTGGGAAACGTCGATCGC
CCCGGACATCAAGAGCGGCAAGCGCGTCGTGATCGCCGCGCACGGCAACAGCATCCGCGCCCTGGTGAAGTACCTCGACA
ACATCTCGGACGACGACATCGTCGGCCTGAACATCCCCAACGGCACGCCGCTCGTCTACGAACTGGACGCCAACCTGAAG
CCCATCCGCCATTACTATCTCGGCGACCAGGAAGCGATCGCCGCGTCGCTCGCCGCCGTGGCTGGCCAGGGCAAGGCGAA
ATAA

Upstream 100 bases:

>100_bases
GGCTGGCGGCCAAATCGGCGCGCATCGCGACGTCATCCGAACAGTTCGGGGTGCACGGTGCCGGCGGCATTATAAAATAG
CGCGTTTCGGCGGCCGCTCG

Downstream 100 bases:

>100_bases
AGCGTAACCGCCGGGCGTAACGGCGCAGGGCACTTCCAACGCCTTTATACTGTCGAAACGCCAGCCCGGGACACGCACCA
GCGGTCCCGGGCCATGTTTA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTQRVPATAQVFSLLIMAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGIAQARQGGRLLREAGFTFDLAYTSVLKRA
IRTLWHVQDEMDLMWIPTRTEWRLNERHYGGLSGLNKAETAAQYGDQQVLVWRRSYDTPPPALEAGDERDAYGNPRYAGL
PREQVPLTECLKDTVARVLPLWETSIAPDIKSGKRVVIAAHGNSIRALVKYLDNISDDDIVGLNIPNGTPLVYELDANLK
PIRHYYLGDQEAIAASLAAVAGQGKAK

Sequences:

>Translated_267_residues
MTQRVPATAQVFSLLIMAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGIAQARQGGRLLREAGFTFDLAYTSVLKRA
IRTLWHVQDEMDLMWIPTRTEWRLNERHYGGLSGLNKAETAAQYGDQQVLVWRRSYDTPPPALEAGDERDAYGNPRYAGL
PREQVPLTECLKDTVARVLPLWETSIAPDIKSGKRVVIAAHGNSIRALVKYLDNISDDDIVGLNIPNGTPLVYELDANLK
PIRHYYLGDQEAIAASLAAVAGQGKAK
>Mature_266_residues
TQRVPATAQVFSLLIMAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGIAQARQGGRLLREAGFTFDLAYTSVLKRAI
RTLWHVQDEMDLMWIPTRTEWRLNERHYGGLSGLNKAETAAQYGDQQVLVWRRSYDTPPPALEAGDERDAYGNPRYAGLP
REQVPLTECLKDTVARVLPLWETSIAPDIKSGKRVVIAAHGNSIRALVKYLDNISDDDIVGLNIPNGTPLVYELDANLKP
IRHYYLGDQEAIAASLAAVAGQGKAK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=253, Percent_Identity=55.3359683794466, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=58.4, Blast_Score=296, Evalue=1e-80,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=56.4, Blast_Score=285, Evalue=4e-77,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=46.8253968253968, Blast_Score=257, Evalue=9e-69,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=46.8253968253968, Blast_Score=257, Evalue=9e-69,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=59.8765432098765, Blast_Score=194, Evalue=9e-50,
Organism=Escherichia coli, GI1786970, Length=251, Percent_Identity=61.3545816733068, Blast_Score=320, Evalue=9e-89,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=51.219512195122, Blast_Score=235, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=32.4414715719064, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324516, Length=296, Percent_Identity=32.4324324324324, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=50.597609561753, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI85725270, Length=255, Percent_Identity=51.3725490196078, Blast_Score=257, Evalue=6e-69,
Organism=Drosophila melanogaster, GI85725272, Length=255, Percent_Identity=51.3725490196078, Blast_Score=257, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24650981, Length=255, Percent_Identity=51.3725490196078, Blast_Score=257, Evalue=6e-69,
Organism=Drosophila melanogaster, GI28571815, Length=257, Percent_Identity=38.1322957198444, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28571817, Length=257, Percent_Identity=38.1322957198444, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24648979, Length=256, Percent_Identity=38.28125, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 29805; Mature: 29674

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRVPATAQVFSLLIMAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGIAQARQGGR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCH
LLREAGFTFDLAYTSVLKRAIRTLWHVQDEMDLMWIPTRTEWRLNERHYGGLSGLNKAET
HHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCCCCCCCHHHH
AAQYGDQQVLVWRRSYDTPPPALEAGDERDAYGNPRYAGLPREQVPLTECLKDTVARVLP
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LWETSIAPDIKSGKRVVIAAHGNSIRALVKYLDNISDDDIVGLNIPNGTPLVYELDANLK
HHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCC
PIRHYYLGDQEAIAASLAAVAGQGKAK
HHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TQRVPATAQVFSLLIMAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGIAQARQGGR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCH
LLREAGFTFDLAYTSVLKRAIRTLWHVQDEMDLMWIPTRTEWRLNERHYGGLSGLNKAET
HHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCCCCCCCHHHH
AAQYGDQQVLVWRRSYDTPPPALEAGDERDAYGNPRYAGLPREQVPLTECLKDTVARVLP
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LWETSIAPDIKSGKRVVIAAHGNSIRALVKYLDNISDDDIVGLNIPNGTPLVYELDANLK
HHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCC
PIRHYYLGDQEAIAASLAAVAGQGKAK
HHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]