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The map label for this gene is yngJ [H]

Identifier: 17544998

GI number: 17544998

Start: 312256

End: 313437

Strand: Reverse

Name: yngJ [H]

Synonym: RSc0279

Alternate gene names: 17544998

Gene position: 313437-312256 (Counterclockwise)

Preceding gene: 17544999

Following gene: 17544997

Centisome position: 8.43

GC content: 66.58

Gene sequence:

>1182_bases
ATGATTGAACTGCCCGGCCTGAGATTCGACCTAGGCGTTGACATCGAAATGCTGCGCTCCGCCGTGCGCGACTGGGCCCA
GGCCGAGCTGGCGCCGCGCGCCGAAGCGATCGACCGCAGCGACCAGTTCCCGATGGACGCCTGGAAGCAGATGGGCGACC
TCGGCGTGCTGGGCATCACGGTGGCGGAGGAATACGGCGGCAGCGGCATGGGCTACCTGGCGCACATGATCGCCATGGAG
GAGATCAGCCGGGCGTCCGCCTCGGTCGGGCTGTCGTATGGCGCGCACTCCAACCTGTGCGTCAACCAGATCCACCGCAA
CGGCACGCCGGCGCAGAAGGCGAAGTACCTGCCCAAGCTGGTGTCGGGCGAGTGGATCGGCGCGCTGGCCATGAGCGAGC
CCAACGCCGGCTCGGACGTCGTCAGCATGAAGCTGCGCGCCGAGTGCCGCGGCGACCGCTACGTGCTCAACGGCACCAAG
ATGTGGATCACCAACGGGCCGGATTGCGACGTGCTGGTCGTCTACGGCAAGACCGAGCCGGAGCTGGGCGCGCGCGGCAT
GACGGCCTTCATCGTCGAGAAAGGCATGAAGGGCTTCTCGGTGGCGCAGAAGCTGGACAAGCTCGGCATGCGCGGCTCGC
ACACGGGCGAGCTGGTGTTCGACAACGTGGAAGTGCCCGCCGAGAACGTCCTGGGCGAGGAAAACGGCGGCACCCGCGTG
CTGATGAGCGGGCTGGACTACGAGCGTGCCGTGCTGTCGGGCGGCCCGATCGGCATCATGCAGGCGTGCATGGACGTGGT
GACCCCGTACATCCACGACCGCAAGCAGTTCGGCCAGAGCATCGGCGAATTCCAGCTGATCCAGGGCAAGATCGCCGACA
TGTACACCACGCTGCAGGCCTGCCGCGCCTACCTGTACACGGTCGGCAAGAACCTCGACGCGCTGGGCCGCGAGCACGTG
CGCCAGGTGCGCAAGGACTGCGCGGGCGTGATCCTCTACACCGCCGAGAAGGCCACCTGGATGGCCGGCGAGGCCATCCA
GATCCTGGGCGGCAACGGCTACATCAACGAATTCCCGACCGGGCGGCTGTGGCGCGACGCCAAGCTGTATGAAATCGGGG
CGGGCACGTCGGAAATCCGGCGCATGCTGATTGGTCGCGAACTGTATGCCGAAACCATGTGA

Upstream 100 bases:

>100_bases
ACCCTCCGATCCGGCGCGCCCGCCACAAGCGGCGCGCGCCTCGCGACCGCCATCCACCCGAGACACCGTCGCGGCCCGAG
CCGCGCCCAAGGAGACCACC

Downstream 100 bases:

>100_bases
CGGGTGGCGTGGCCGCCATAGGCGAAACGGATAAGGCGCCGATGCAGGACGGCGAAGCCCATACAATCTACCCATTGCGG
CCCCCGCCCTGCCCGAGCGC

Product: acyl-CoA dehydrogenase oxidoreductase

Products: 3-methylbut-2-enoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MIELPGLRFDLGVDIEMLRSAVRDWAQAELAPRAEAIDRSDQFPMDAWKQMGDLGVLGITVAEEYGGSGMGYLAHMIAME
EISRASASVGLSYGAHSNLCVNQIHRNGTPAQKAKYLPKLVSGEWIGALAMSEPNAGSDVVSMKLRAECRGDRYVLNGTK
MWITNGPDCDVLVVYGKTEPELGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFDNVEVPAENVLGEENGGTRV
LMSGLDYERAVLSGGPIGIMQACMDVVTPYIHDRKQFGQSIGEFQLIQGKIADMYTTLQACRAYLYTVGKNLDALGREHV
RQVRKDCAGVILYTAEKATWMAGEAIQILGGNGYINEFPTGRLWRDAKLYEIGAGTSEIRRMLIGRELYAETM

Sequences:

>Translated_393_residues
MIELPGLRFDLGVDIEMLRSAVRDWAQAELAPRAEAIDRSDQFPMDAWKQMGDLGVLGITVAEEYGGSGMGYLAHMIAME
EISRASASVGLSYGAHSNLCVNQIHRNGTPAQKAKYLPKLVSGEWIGALAMSEPNAGSDVVSMKLRAECRGDRYVLNGTK
MWITNGPDCDVLVVYGKTEPELGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFDNVEVPAENVLGEENGGTRV
LMSGLDYERAVLSGGPIGIMQACMDVVTPYIHDRKQFGQSIGEFQLIQGKIADMYTTLQACRAYLYTVGKNLDALGREHV
RQVRKDCAGVILYTAEKATWMAGEAIQILGGNGYINEFPTGRLWRDAKLYEIGAGTSEIRRMLIGRELYAETM
>Mature_393_residues
MIELPGLRFDLGVDIEMLRSAVRDWAQAELAPRAEAIDRSDQFPMDAWKQMGDLGVLGITVAEEYGGSGMGYLAHMIAME
EISRASASVGLSYGAHSNLCVNQIHRNGTPAQKAKYLPKLVSGEWIGALAMSEPNAGSDVVSMKLRAECRGDRYVLNGTK
MWITNGPDCDVLVVYGKTEPELGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFDNVEVPAENVLGEENGGTRV
LMSGLDYERAVLSGGPIGIMQACMDVVTPYIHDRKQFGQSIGEFQLIQGKIADMYTTLQACRAYLYTVGKNLDALGREHV
RQVRKDCAGVILYTAEKATWMAGEAIQILGGNGYINEFPTGRLWRDAKLYEIGAGTSEIRRMLIGRELYAETM

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=64.2857142857143, Blast_Score=495, Evalue=1e-140,
Organism=Homo sapiens, GI226958414, Length=366, Percent_Identity=64.4808743169399, Blast_Score=477, Evalue=1e-135,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=38.8739946380697, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=33.6, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI21361497, Length=360, Percent_Identity=36.6666666666667, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4501857, Length=386, Percent_Identity=31.8652849740933, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=32.9015544041451, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=32.9015544041451, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI76496475, Length=345, Percent_Identity=35.0724637681159, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4557235, Length=345, Percent_Identity=35.0724637681159, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4503943, Length=388, Percent_Identity=32.9896907216495, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI7656849, Length=368, Percent_Identity=29.0760869565217, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI7669494, Length=358, Percent_Identity=34.0782122905028, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI48976061, Length=288, Percent_Identity=25.6944444444444, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI211971008, Length=288, Percent_Identity=25.6944444444444, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI38505218, Length=285, Percent_Identity=21.7543859649123, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=28.3116883116883, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=28.2722513089005, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081702, Length=275, Percent_Identity=25.4545454545455, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082384, Length=259, Percent_Identity=25.0965250965251, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=63.4920634920635, Blast_Score=479, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=35.0684931506849, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17569725, Length=385, Percent_Identity=33.5064935064935, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17534899, Length=386, Percent_Identity=33.6787564766839, Blast_Score=221, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=32.8767123287671, Blast_Score=214, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17570075, Length=390, Percent_Identity=31.7948717948718, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=34.6478873239437, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=38.3211678832117, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=30.3191489361702, Blast_Score=199, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=40.2597402597403, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=283, Percent_Identity=36.3957597173145, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17534353, Length=388, Percent_Identity=29.8969072164948, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=267, Percent_Identity=32.5842696629214, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17505929, Length=363, Percent_Identity=30.3030303030303, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17551932, Length=372, Percent_Identity=27.1505376344086, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=27.8688524590164, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=288, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=64.26735218509, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=39.3617021276596, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=36.436170212766, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24666513, Length=382, Percent_Identity=34.2931937172775, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24660351, Length=387, Percent_Identity=32.8165374677003, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281363737, Length=376, Percent_Identity=33.7765957446808, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=31.758530183727, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24652780, Length=327, Percent_Identity=23.5474006116208, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.10

Molecular weight: Translated: 42966; Mature: 42966

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELPGLRFDLGVDIEMLRSAVRDWAQAELAPRAEAIDRSDQFPMDAWKQMGDLGVLGIT
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEE
VAEEYGGSGMGYLAHMIAMEEISRASASVGLSYGAHSNLCVNQIHRNGTPAQKAKYLPKL
EEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHH
VSGEWIGALAMSEPNAGSDVVSMKLRAECRGDRYVLNGTKMWITNGPDCDVLVVYGKTEP
HCCCCEEEEEECCCCCCCHHEEEEEHHHCCCCEEEECCEEEEEECCCCCCEEEEECCCCC
ELGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFDNVEVPAENVLGEENGGTRV
CCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHCCCCCCCCEE
LMSGLDYERAVLSGGPIGIMQACMDVVTPYIHDRKQFGQSIGEFQLIQGKIADMYTTLQA
EEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CRAYLYTVGKNLDALGREHVRQVRKDCAGVILYTAEKATWMAGEAIQILGGNGYINEFPT
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCEEEEECCCCCCCCCCC
GRLWRDAKLYEIGAGTSEIRRMLIGRELYAETM
CCEECCCEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIELPGLRFDLGVDIEMLRSAVRDWAQAELAPRAEAIDRSDQFPMDAWKQMGDLGVLGIT
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEE
VAEEYGGSGMGYLAHMIAMEEISRASASVGLSYGAHSNLCVNQIHRNGTPAQKAKYLPKL
EEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHH
VSGEWIGALAMSEPNAGSDVVSMKLRAECRGDRYVLNGTKMWITNGPDCDVLVVYGKTEP
HCCCCEEEEEECCCCCCCHHEEEEEHHHCCCCEEEECCEEEEEECCCCCCEEEEECCCCC
ELGARGMTAFIVEKGMKGFSVAQKLDKLGMRGSHTGELVFDNVEVPAENVLGEENGGTRV
CCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHCCCCCCCCEE
LMSGLDYERAVLSGGPIGIMQACMDVVTPYIHDRKQFGQSIGEFQLIQGKIADMYTTLQA
EEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CRAYLYTVGKNLDALGREHVRQVRKDCAGVILYTAEKATWMAGEAIQILGGNGYINEFPT
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCEEEEECCCCCCCCCCC
GRLWRDAKLYEIGAGTSEIRRMLIGRELYAETM
CCEECCCEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-methylbutanoyl-CoA; acceptor

Specific reaction: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]