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The map label for this gene is can [H]

Identifier: 17544996

GI number: 17544996

Start: 309615

End: 310295

Strand: Reverse

Name: can [H]

Synonym: RSc0277

Alternate gene names: 17544996

Gene position: 310295-309615 (Counterclockwise)

Preceding gene: 17544997

Following gene: 17544995

Centisome position: 8.35

GC content: 63.58

Gene sequence:

>681_bases
ATGCCACATCGCATCAAGGAACTCTTCGAGAACAACCGCAAGTGGGTCGAGCGCGTCAATGCCGAAGACCCGGCGTTCTT
CTCCGGCCTGGCCAACCAGCAAAACCCCGAATACCTGTGGATCGGCTGCTCCGACTCGCGCGTGCCGGCCAACCAGATCA
TCGGCCTGCCGCCGGGCGAAGTGTTCGTCCATCGCAACATCGCCAACGTGGTGGTGCACTCGGACCTGAACTGCCTGTCG
GTGCTGCAGTTCGCGGTGGAAGTGCTGAAGATCCGGCACATCACCGTGGTCGGGCACTACGGCTGCTCGGGCGTGAAGGC
CGCGCTGACCAACCAGCGCTTCGGGCTGGCGGACAACTGGATCCGCCACGTGCGCGACGTCGCCGAGCAGCACGACACCT
ACCTCGGCACGGTGATCCGCGAGCAGGACCGGCACGACCGGCTGTGCGAGCTCAATGTCATCCACCAGGTCAACAACGTG
TGCCTGACCACCGTCGTGCAGGACGCCTGGGAACGCGGGCAGCCGCTGACCGTGCATGGCTGGATCTACGGCGTGAAGGA
CGGGCTGCTGCGCAATCTGGGGATGGCGGTGAACTCCAACGAAGAACTGCATGGCCAGTTGGCGAGTGCCTGGTTGAATT
ACGGGAAGAAGGGGAGTGTGCCTACGCCTGTGGGGTATTGA

Upstream 100 bases:

>100_bases
AACGCTTCGTCAACCGCTACGGCGACAGCGCGCCGGGAAACGCAGCGACACCGCTGCGGCGCGCCGCTGCCTGAACCCCG
CAACAACAAGACGGAAACAC

Downstream 100 bases:

>100_bases
GGCTTTTGTTTGGGGGGAGGTGATGGGCTTGGGTTATGTGCTTGTGGTCCATCCCGGGTTTCGTCCCCTGCCGGGGCCGA
CTCACTTTCTTTGTCTTGCC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPHRIKELFENNRKWVERVNAEDPAFFSGLANQQNPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLNCLS
VLQFAVEVLKIRHITVVGHYGCSGVKAALTNQRFGLADNWIRHVRDVAEQHDTYLGTVIREQDRHDRLCELNVIHQVNNV
CLTTVVQDAWERGQPLTVHGWIYGVKDGLLRNLGMAVNSNEELHGQLASAWLNYGKKGSVPTPVGY

Sequences:

>Translated_226_residues
MPHRIKELFENNRKWVERVNAEDPAFFSGLANQQNPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLNCLS
VLQFAVEVLKIRHITVVGHYGCSGVKAALTNQRFGLADNWIRHVRDVAEQHDTYLGTVIREQDRHDRLCELNVIHQVNNV
CLTTVVQDAWERGQPLTVHGWIYGVKDGLLRNLGMAVNSNEELHGQLASAWLNYGKKGSVPTPVGY
>Mature_225_residues
PHRIKELFENNRKWVERVNAEDPAFFSGLANQQNPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLNCLSV
LQFAVEVLKIRHITVVGHYGCSGVKAALTNQRFGLADNWIRHVRDVAEQHDTYLGTVIREQDRHDRLCELNVIHQVNNVC
LTTVVQDAWERGQPLTVHGWIYGVKDGLLRNLGMAVNSNEELHGQLASAWLNYGKKGSVPTPVGY

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=199, Percent_Identity=53.7688442211055, Blast_Score=236, Evalue=9e-64,
Organism=Escherichia coli, GI1786534, Length=198, Percent_Identity=28.2828282828283, Blast_Score=77, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=198, Percent_Identity=33.8383838383838, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25447; Mature: 25316

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHRIKELFENNRKWVERVNAEDPAFFSGLANQQNPEYLWIGCSDSRVPANQIIGLPPGE
CCHHHHHHHHCCHHHHHHCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHEECCCCCC
VFVHRNIANVVVHSDLNCLSVLQFAVEVLKIRHITVVGHYGCSGVKAALTNQRFGLADNW
EEEECCHHHEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCCCHHHH
IRHVRDVAEQHDTYLGTVIREQDRHDRLCELNVIHQVNNVCLTTVVQDAWERGQPLTVHG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
WIYGVKDGLLRNLGMAVNSNEELHGQLASAWLNYGKKGSVPTPVGY
EEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PHRIKELFENNRKWVERVNAEDPAFFSGLANQQNPEYLWIGCSDSRVPANQIIGLPPGE
CHHHHHHHHCCHHHHHHCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHEECCCCCC
VFVHRNIANVVVHSDLNCLSVLQFAVEVLKIRHITVVGHYGCSGVKAALTNQRFGLADNW
EEEECCHHHEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCCCHHHH
IRHVRDVAEQHDTYLGTVIREQDRHDRLCELNVIHQVNNVCLTTVVQDAWERGQPLTVHG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
WIYGVKDGLLRNLGMAVNSNEELHGQLASAWLNYGKKGSVPTPVGY
EEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]