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The map label for this gene is ycjZ [C]

Identifier: 17544924

GI number: 17544924

Start: 227886

End: 228788

Strand: Reverse

Name: ycjZ [C]

Synonym: RSc0205

Alternate gene names: 17544924

Gene position: 228788-227886 (Counterclockwise)

Preceding gene: 17544928

Following gene: 17544918

Centisome position: 6.16

GC content: 61.02

Gene sequence:

>903_bases
ATGCCCAGACACAACCTCAACGATCTGCTGGCGTTCGTGACAGTGGCGCGCGAAGGCAGCTTTACGCGGGCGGCAGCTAA
GCTGGGCGTGACCCAATCGGCGCTCAGCCAAACGGTATCGGGCCTGGAAACACGGCTGAAGATCCGGCTCCTCACACGCA
CCACACGCAGCGTCTCACCCACCGCTGCCGGCGAACGTCTGCTCCAAGCCATCGGTCATCGCTTCGATGAGATCGAATCT
GAACTGGAGGCATTGACGGAGCTGCGCGACAAGCCGGCCGGGACGGTGCGCATCACGTGTGGCGATCAGATCATTAGGAC
AACGCTGTTGCCCAAGCTGATGCCATTGCTACACGAATATCCCGACATCAAGCTGGAGCTCGACATCAACTACGGATTCC
GAGACATCGTTGCTGACCGCTTCGACGCAGGGGTACGTTTCAGCGGCACGGTCGACAAGGACATGATCGCTGTACGCATC
GGACCCGACATGCGCATGGCGGTGGTCGCTTCGCCTGCCTACTTCGCCAAGCACCCTGCGCCGAAGACCCCTCGCGATCT
AGTGCATCACCAGTGCATCAACATTCGGTTTCCGACGTACGGGGGACTGGATGTCTGGGAGTTTGAGCGTCGTGGACGCA
AGCTGAAGATCCGTGTCGACGGTCAGCTTGTCGTCAATACGACCCCCCATATTGCCGCGGCTGCGGTGGGCGGCTTGGGC
GTGGCCTATCTGCCCGAGGATGAATTTTGGCCCCACCTCGAAGAAGGACGCCTGGTGCGCGTACTGGAAGACTGGTGCCC
GCCCTTCTCGGGCTATCACCTGTATTACCCCAGCCGTCGGCAGCCATCGCCCGCGTTTGCGCTCGTTCTCGACGCACTGC
GTATGGGGCGTCAGGTGAAGTGA

Upstream 100 bases:

>100_bases
CGCATCGACATTCTTGCGGAACGGGGTAAGCCTGATAAGCTAATGAATGCTTAATTGCTCTATAAGCAGAGCTAATCAAT
GTTCGATGGGACACTGAGCG

Downstream 100 bases:

>100_bases
CCCTACACCAAGAAACAGTACCACTGAGAAGTAGAGAACCCTCGCCAACCACCCTTCCGAAGCCGACGAACCGGCATGGC
ACCTGTATGAGGAAGTATTC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPRHNLNDLLAFVTVAREGSFTRAAAKLGVTQSALSQTVSGLETRLKIRLLTRTTRSVSPTAAGERLLQAIGHRFDEIES
ELEALTELRDKPAGTVRITCGDQIIRTTLLPKLMPLLHEYPDIKLELDINYGFRDIVADRFDAGVRFSGTVDKDMIAVRI
GPDMRMAVVASPAYFAKHPAPKTPRDLVHHQCINIRFPTYGGLDVWEFERRGRKLKIRVDGQLVVNTTPHIAAAAVGGLG
VAYLPEDEFWPHLEEGRLVRVLEDWCPPFSGYHLYYPSRRQPSPAFALVLDALRMGRQVK

Sequences:

>Translated_300_residues
MPRHNLNDLLAFVTVAREGSFTRAAAKLGVTQSALSQTVSGLETRLKIRLLTRTTRSVSPTAAGERLLQAIGHRFDEIES
ELEALTELRDKPAGTVRITCGDQIIRTTLLPKLMPLLHEYPDIKLELDINYGFRDIVADRFDAGVRFSGTVDKDMIAVRI
GPDMRMAVVASPAYFAKHPAPKTPRDLVHHQCINIRFPTYGGLDVWEFERRGRKLKIRVDGQLVVNTTPHIAAAAVGGLG
VAYLPEDEFWPHLEEGRLVRVLEDWCPPFSGYHLYYPSRRQPSPAFALVLDALRMGRQVK
>Mature_299_residues
PRHNLNDLLAFVTVAREGSFTRAAAKLGVTQSALSQTVSGLETRLKIRLLTRTTRSVSPTAAGERLLQAIGHRFDEIESE
LEALTELRDKPAGTVRITCGDQIIRTTLLPKLMPLLHEYPDIKLELDINYGFRDIVADRFDAGVRFSGTVDKDMIAVRIG
PDMRMAVVASPAYFAKHPAPKTPRDLVHHQCINIRFPTYGGLDVWEFERRGRKLKIRVDGQLVVNTTPHIAAAAVGGLGV
AYLPEDEFWPHLEEGRLVRVLEDWCPPFSGYHLYYPSRRQPSPAFALVLDALRMGRQVK

Specific function: May have a role in the regulation of oprD expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=294, Percent_Identity=48.9795918367347, Blast_Score=300, Evalue=7e-83,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=40.3389830508475, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI1789440, Length=271, Percent_Identity=27.3062730627306, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786401, Length=276, Percent_Identity=29.3478260869565, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=28.719723183391, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789639, Length=243, Percent_Identity=30.8641975308642, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI145693193, Length=278, Percent_Identity=30.9352517985612, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790011, Length=260, Percent_Identity=25.7692307692308, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786448, Length=308, Percent_Identity=26.2987012987013, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=125, Percent_Identity=39.2, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI145693105, Length=163, Percent_Identity=31.2883435582822, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786713, Length=271, Percent_Identity=27.3062730627306, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789173, Length=270, Percent_Identity=27.037037037037, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082132, Length=261, Percent_Identity=26.0536398467433, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=170, Percent_Identity=30, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786508, Length=106, Percent_Identity=38.6792452830189, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788706, Length=239, Percent_Identity=23.8493723849372, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=28, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=30.6451612903226, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33631; Mature: 33500

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRHNLNDLLAFVTVAREGSFTRAAAKLGVTQSALSQTVSGLETRLKIRLLTRTTRSVSP
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCC
TAAGERLLQAIGHRFDEIESELEALTELRDKPAGTVRITCGDQIIRTTLLPKLMPLLHEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCC
PDIKLELDINYGFRDIVADRFDAGVRFSGTVDKDMIAVRIGPDMRMAVVASPAYFAKHPA
CCEEEEEEECCCHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEECCHHHHCCCC
PKTPRDLVHHQCINIRFPTYGGLDVWEFERRGRKLKIRVDGQLVVNTTPHIAAAAVGGLG
CCCHHHHHHHHHEEEECCCCCCCCHHHHHHCCCEEEEEECCEEEEECCCCHHHHHHCCCC
VAYLPEDEFWPHLEEGRLVRVLEDWCPPFSGYHLYYPSRRQPSPAFALVLDALRMGRQVK
EEECCCCCCCCCCCCCCEEEHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRHNLNDLLAFVTVAREGSFTRAAAKLGVTQSALSQTVSGLETRLKIRLLTRTTRSVSP
CCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCC
TAAGERLLQAIGHRFDEIESELEALTELRDKPAGTVRITCGDQIIRTTLLPKLMPLLHEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCC
PDIKLELDINYGFRDIVADRFDAGVRFSGTVDKDMIAVRIGPDMRMAVVASPAYFAKHPA
CCEEEEEEECCCHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEECCHHHHCCCC
PKTPRDLVHHQCINIRFPTYGGLDVWEFERRGRKLKIRVDGQLVVNTTPHIAAAAVGGLG
CCCHHHHHHHHHEEEECCCCCCCCHHHHHHCCCEEEEEECCEEEEECCCCHHHHHHCCCC
VAYLPEDEFWPHLEEGRLVRVLEDWCPPFSGYHLYYPSRRQPSPAFALVLDALRMGRQVK
EEECCCCCCCCCCCCCCEEEHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]