Click here to switch to the map view.

The map label for this gene is fnr [H]

Identifier: 17544909

GI number: 17544909

Start: 211194

End: 211994

Strand: Reverse

Name: fnr [H]

Synonym: RSc0190

Alternate gene names: 17544909

Gene position: 211994-211194 (Counterclockwise)

Preceding gene: 17544912

Following gene: 17544902

Centisome position: 5.7

GC content: 62.05

Gene sequence:

>801_bases
ATGATTCCGAGCACGCTCAAGGCCCAGACATCCGCCGACGTGACCCGCCCCACGCCCCTGCCTCAACTCAAGCTGGTTCG
CGATGCAACACAGGCCCGCCAAACAGTAAGCCCAGCACTGAGCAGTCAGTGCGCCAACTGCATGATGCACTGGGTGTGCA
TCGCGGGCGCCGTGCCGTCCACCCAGCAGGAACGCGTGGATCGGATGGTCCATACGTGGCGCAAGGTCGGCAAGGGCGAA
GCGCTTTTCCGCGCCGGCGACACCTTCCATGCGCTGTATGCGATCCGCTCCGGCTCATTCAAGACGGTGGTATCGCACCC
CAACGGCTCAAGCCATGTCACGGGCTTCCAGTTGGCCGGCGAAACCCTCGGGCTCGACGGCATTGCCGCCGATCGCCATA
CGTGCGATGCGATTGCCCTGGAAGACAGCACCGTATGCTCGATGCCGTTTCACTGTGTCGAAGACCTGTGCCAGGCAATT
CGCCCGCTGCAGCACCGGCTTCACCAGTTGCTGGCAGAGGAAATCGTGCGTGAATCCGGGCTGATGTTGCTGCTGGCAAG
GCTCACCGCAGAGGCGCGCGTTGCGACCTTCCTGCTGAACCTGTCCTCACGCATGCAAGACCGGGGCTATTCTGGTTCCT
GCTTCACGCTGCGCATGACGCGTGAAGAGATTGGCAGCTATCTGGGCATGCAACTGGAAACGGTCAGCCGAGCGCTGTCG
CGGTTCCAGCGCGAGGGTTGGATCTCGGTAAACGGCAAGCAAATCGAACTCGCCAACAAGGCAGCGCTCAGCGAGCTATA
G

Upstream 100 bases:

>100_bases
CATACGGGCACCACGCCCTGGCTGCGTGCGGTGGCCGATCCTCAACCGCTCCAAACAGACGCGGGAGCCGCAGACAGCAC
ATGTCTTCCGGAGACCCTTC

Downstream 100 bases:

>100_bases
CCGTATACGCGAATACGATGCAAACACGCCACTCTCGCGGGTGGCGTGTTTGTCATCATGGCGCGAGCTGCAGATGGTCG
ATGACCTCCGTCACGCCAGG

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MIPSTLKAQTSADVTRPTPLPQLKLVRDATQARQTVSPALSSQCANCMMHWVCIAGAVPSTQQERVDRMVHTWRKVGKGE
ALFRAGDTFHALYAIRSGSFKTVVSHPNGSSHVTGFQLAGETLGLDGIAADRHTCDAIALEDSTVCSMPFHCVEDLCQAI
RPLQHRLHQLLAEEIVRESGLMLLLARLTAEARVATFLLNLSSRMQDRGYSGSCFTLRMTREEIGSYLGMQLETVSRALS
RFQREGWISVNGKQIELANKAALSEL

Sequences:

>Translated_266_residues
MIPSTLKAQTSADVTRPTPLPQLKLVRDATQARQTVSPALSSQCANCMMHWVCIAGAVPSTQQERVDRMVHTWRKVGKGE
ALFRAGDTFHALYAIRSGSFKTVVSHPNGSSHVTGFQLAGETLGLDGIAADRHTCDAIALEDSTVCSMPFHCVEDLCQAI
RPLQHRLHQLLAEEIVRESGLMLLLARLTAEARVATFLLNLSSRMQDRGYSGSCFTLRMTREEIGSYLGMQLETVSRALS
RFQREGWISVNGKQIELANKAALSEL
>Mature_266_residues
MIPSTLKAQTSADVTRPTPLPQLKLVRDATQARQTVSPALSSQCANCMMHWVCIAGAVPSTQQERVDRMVHTWRKVGKGE
ALFRAGDTFHALYAIRSGSFKTVVSHPNGSSHVTGFQLAGETLGLDGIAADRHTCDAIALEDSTVCSMPFHCVEDLCQAI
RPLQHRLHQLLAEEIVRESGLMLLLARLTAEARVATFLLNLSSRMQDRGYSGSCFTLRMTREEIGSYLGMQLETVSRALS
RFQREGWISVNGKQIELANKAALSEL

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=234, Percent_Identity=38.4615384615385, Blast_Score=184, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 29253; Mature: 29253

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSTLKAQTSADVTRPTPLPQLKLVRDATQARQTVSPALSSQCANCMMHWVCIAGAVPS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TQQERVDRMVHTWRKVGKGEALFRAGDTFHALYAIRSGSFKTVVSHPNGSSHVTGFQLAG
HHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHEECC
ETLGLDGIAADRHTCDAIALEDSTVCSMPFHCVEDLCQAIRPLQHRLHQLLAEEIVRESG
CCCCCCCCCCCCCCCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LMLLLARLTAEARVATFLLNLSSRMQDRGYSGSCFTLRMTREEIGSYLGMQLETVSRALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCHHHHHHHHHH
RFQREGWISVNGKQIELANKAALSEL
HHHHCCCEEECCCEEEHHHHHHHHCC
>Mature Secondary Structure
MIPSTLKAQTSADVTRPTPLPQLKLVRDATQARQTVSPALSSQCANCMMHWVCIAGAVPS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TQQERVDRMVHTWRKVGKGEALFRAGDTFHALYAIRSGSFKTVVSHPNGSSHVTGFQLAG
HHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHEECC
ETLGLDGIAADRHTCDAIALEDSTVCSMPFHCVEDLCQAIRPLQHRLHQLLAEEIVRESG
CCCCCCCCCCCCCCCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LMLLLARLTAEARVATFLLNLSSRMQDRGYSGSCFTLRMTREEIGSYLGMQLETVSRALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCHHHHHHHHHH
RFQREGWISVNGKQIELANKAALSEL
HHHHCCCEEECCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA