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The map label for this gene is nahR [H]

Identifier: 17544863

GI number: 17544863

Start: 165575

End: 166540

Strand: Reverse

Name: nahR [H]

Synonym: RSc0144

Alternate gene names: 17544863

Gene position: 166540-165575 (Counterclockwise)

Preceding gene: 17544864

Following gene: 17544858

Centisome position: 4.48

GC content: 71.22

Gene sequence:

>966_bases
ATGCGCGATATCAGAACCCTGGACCTGAACCTGCTCAAAGCGCTGGACGCGCTGCTGGACGAGCGCAACGTCACGCGCGC
AGCGGTCCGGCTGGCGATCACGCAACCGGCGATGAGCGGCATGCTGACGCGGCTGCGCGACAGCTTCGACGACCCGCTCT
TCGTGCGCACGCAGCGCGGCGTCGTGCCCACCCAGCGTGCGCTGGAGCTGGCCGGACCGGTCAAGCAGGTGCTGGGCGAA
GTCGATGCGCTGCTTCAGCCGCCGACCTTCGACCCGTCGACGGCGAGCCTCACGCTGTCCGTGGCGGCCACCGACTATGG
GCTGCGGGCCGTGGTGGTGCCGTTCCTGCTGGCGCTCCGGCAGCGCGCCCCGCACGTCCGGCTGGCAGCGCGGCCGGTCA
AGGATGCCCTGGTGCAGGCGCAGCTCGAACGCGGCGAGCTCGACCTCGCCCTGCTGACGCCGGACAGCACGCCGGCCGAC
CTGTACGCCCGCCACCTGTTCGAAGAGCGCTACGTCTGCGCGCTGCGCCGGGACCATCCGGATGCGAGAGACGGCCGCCT
GTCGCTCGACCGGTTCTGCGCCCTCGATCATGCGCTGGTGTCGTACGTGGGGGGCGGTTTCGCGGGCGTGACGGATGAAG
CGCTGGCCAGGCTCGGCCGGACGCGCCGGGTGACCTTGTCCGTGGGCAGTTTCCTGATCCTGCCCGAGATCCTGCGCGCG
AGCGACCTGGTCGCCGTGGTGCCGCGGCGGCTGGTTGCGCAGGTGGAGGGCCTGGCGCTGCTCGATCCGCCCATCGAGAT
CCCGGGCTTTACCAAGGTCGTCGCCTGGCATGCGCGCACGCATCGGCATCCCGGCCACCGCTGGCTGCGCGCGCTGCTGT
TCGAGACGTGCGGCACGCCGGATACGGCCCCCTCGCAAGTGCCCGCGGAAAGCGGATCGGACCTCCACTTCCCTGCGGGT
ACCTGA

Upstream 100 bases:

>100_bases
ACGCGGCCCAGCATCGTTGGATTGTGCTGCCGGCGCTCCTTGTGCAACCGAAGGCCGAGCGCTATAAGACGGAAGCCCTC
CTCATCGCCAAGAAATCAGC

Downstream 100 bases:

>100_bases
CCCGCCAGCCAGCCACCAGGTTACCGACCGGCTGCCGCGCGCACGCCCTCGACCGCGCTGCGCGCCAGACCGTCGACCCA
CGCCTGGTGGGCATTGAGCA

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRDIRTLDLNLLKALDALLDERNVTRAAVRLAITQPAMSGMLTRLRDSFDDPLFVRTQRGVVPTQRALELAGPVKQVLGE
VDALLQPPTFDPSTASLTLSVAATDYGLRAVVVPFLLALRQRAPHVRLAARPVKDALVQAQLERGELDLALLTPDSTPAD
LYARHLFEERYVCALRRDHPDARDGRLSLDRFCALDHALVSYVGGGFAGVTDEALARLGRTRRVTLSVGSFLILPEILRA
SDLVAVVPRRLVAQVEGLALLDPPIEIPGFTKVVAWHARTHRHPGHRWLRALLFETCGTPDTAPSQVPAESGSDLHFPAG
T

Sequences:

>Translated_321_residues
MRDIRTLDLNLLKALDALLDERNVTRAAVRLAITQPAMSGMLTRLRDSFDDPLFVRTQRGVVPTQRALELAGPVKQVLGE
VDALLQPPTFDPSTASLTLSVAATDYGLRAVVVPFLLALRQRAPHVRLAARPVKDALVQAQLERGELDLALLTPDSTPAD
LYARHLFEERYVCALRRDHPDARDGRLSLDRFCALDHALVSYVGGGFAGVTDEALARLGRTRRVTLSVGSFLILPEILRA
SDLVAVVPRRLVAQVEGLALLDPPIEIPGFTKVVAWHARTHRHPGHRWLRALLFETCGTPDTAPSQVPAESGSDLHFPAG
T
>Mature_321_residues
MRDIRTLDLNLLKALDALLDERNVTRAAVRLAITQPAMSGMLTRLRDSFDDPLFVRTQRGVVPTQRALELAGPVKQVLGE
VDALLQPPTFDPSTASLTLSVAATDYGLRAVVVPFLLALRQRAPHVRLAARPVKDALVQAQLERGELDLALLTPDSTPAD
LYARHLFEERYVCALRRDHPDARDGRLSLDRFCALDHALVSYVGGGFAGVTDEALARLGRTRRVTLSVGSFLILPEILRA
SDLVAVVPRRLVAQVEGLALLDPPIEIPGFTKVVAWHARTHRHPGHRWLRALLFETCGTPDTAPSQVPAESGSDLHFPAG
T

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=298, Percent_Identity=27.1812080536913, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081766, Length=255, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790147, Length=300, Percent_Identity=27.3333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790399, Length=182, Percent_Identity=29.6703296703297, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35130; Mature: 35130

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50931 HTH_LYSR ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDIRTLDLNLLKALDALLDERNVTRAAVRLAITQPAMSGMLTRLRDSFDDPLFVRTQRG
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
VVPTQRALELAGPVKQVLGEVDALLQPPTFDPSTASLTLSVAATDYGLRAVVVPFLLALR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHH
QRAPHVRLAARPVKDALVQAQLERGELDLALLTPDSTPADLYARHLFEERYVCALRRDHP
HCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
DARDGRLSLDRFCALDHALVSYVGGGFAGVTDEALARLGRTRRVTLSVGSFLILPEILRA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHH
SDLVAVVPRRLVAQVEGLALLDPPIEIPGFTKVVAWHARTHRHPGHRWLRALLFETCGTP
HHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
DTAPSQVPAESGSDLHFPAGT
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDIRTLDLNLLKALDALLDERNVTRAAVRLAITQPAMSGMLTRLRDSFDDPLFVRTQRG
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
VVPTQRALELAGPVKQVLGEVDALLQPPTFDPSTASLTLSVAATDYGLRAVVVPFLLALR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHH
QRAPHVRLAARPVKDALVQAQLERGELDLALLTPDSTPADLYARHLFEERYVCALRRDHP
HCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
DARDGRLSLDRFCALDHALVSYVGGGFAGVTDEALARLGRTRRVTLSVGSFLILPEILRA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHH
SDLVAVVPRRLVAQVEGLALLDPPIEIPGFTKVVAWHARTHRHPGHRWLRALLFETCGTP
HHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
DTAPSQVPAESGSDLHFPAGT
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]