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The map label for this gene is dksA [H]

Identifier: 17544765

GI number: 17544765

Start: 50669

End: 51088

Strand: Reverse

Name: dksA [H]

Synonym: RSc0046

Alternate gene names: 17544765

Gene position: 51088-50669 (Counterclockwise)

Preceding gene: 17544766

Following gene: 17544764

Centisome position: 1.37

GC content: 63.33

Gene sequence:

>420_bases
ATGAGCAGCAAGAAACTACTCACCGAAGCCGAAATCCTGAAGATGGGCGACAAGGATTACATGAACGAGGCCCAGCTCGC
CTTCTTCAAGGACCGGCTTGAAAAGCTCCGCGACGACATTCTCAAGAATGCCGGCCAGACCACCGAGCACCTGCGCGAAA
CCGTGATCGTGCCGGACCCGGCCGACCGCGCCACGATCGAGGAAGAGCACGCGCTGGAACTGCGCACCCGCGATCGCGAG
CGCAAGCTGCTCAAGAAGGTCGAGCAGTCGATCGCCCGCATCGACGAGGGCAACTATGGCTACTGCGACGAAACCGGCGA
GCCGATCGGCATCCCGCGTCTGCTGGCCCGCCCGACCGCCACGCTGACGCTGGAGGCGCAGGAGCGCCGCGAAAAGCGCC
AGAAGCTGTTTGGCGACTGA

Upstream 100 bases:

>100_bases
CAAGCCCGCCGCCAGCCAGAACATGTCCGGCGCATCCCCGCGCGAGGACAACGCGACAGCCGACACGGCGCGCGATTTAC
CAGGATCATCCGCAGCAACC

Downstream 100 bases:

>100_bases
CGTGCTCGTCGACCCAGCCTGACCCCGCAGCCCGGTGATCGCCGGGCTGTTTGCTTTGTAGGCACTGCCATGACTCGACC
CCTTCCCGTCACCGTGCTGT

Product: DNAK suppressor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MSSKKLLTEAEILKMGDKDYMNEAQLAFFKDRLEKLRDDILKNAGQTTEHLRETVIVPDPADRATIEEEHALELRTRDRE
RKLLKKVEQSIARIDEGNYGYCDETGEPIGIPRLLARPTATLTLEAQERREKRQKLFGD

Sequences:

>Translated_139_residues
MSSKKLLTEAEILKMGDKDYMNEAQLAFFKDRLEKLRDDILKNAGQTTEHLRETVIVPDPADRATIEEEHALELRTRDRE
RKLLKKVEQSIARIDEGNYGYCDETGEPIGIPRLLARPTATLTLEAQERREKRQKLFGD
>Mature_138_residues
SSKKLLTEAEILKMGDKDYMNEAQLAFFKDRLEKLRDDILKNAGQTTEHLRETVIVPDPADRATIEEEHALELRTRDRER
KLLKKVEQSIARIDEGNYGYCDETGEPIGIPRLLARPTATLTLEAQERREKRQKLFGD

Specific function: Dosage-Dependent Suppressor Of A Dnak Deletion Mutation. It Suppressed Not Only The Temperature-Sensitive Growth But Also The Filamentous Phenotype Of The Dnak Deletion Strain, While The Defect Of Lambda Growth Is Not Suppressed. [C]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=118, Percent_Identity=47.4576271186441, Blast_Score=109, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 16084; Mature: 15952

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKKLLTEAEILKMGDKDYMNEAQLAFFKDRLEKLRDDILKNAGQTTEHLRETVIVPDP
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
ADRATIEEEHALELRTRDRERKLLKKVEQSIARIDEGNYGYCDETGEPIGIPRLLARPTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCC
TLTLEAQERREKRQKLFGD
EEEECHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSKKLLTEAEILKMGDKDYMNEAQLAFFKDRLEKLRDDILKNAGQTTEHLRETVIVPDP
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
ADRATIEEEHALELRTRDRERKLLKKVEQSIARIDEGNYGYCDETGEPIGIPRLLARPTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCC
TLTLEAQERREKRQKLFGD
EEEECHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9555902 [H]