Click here to switch to the map view.

The map label for this gene is mocR [H]

Identifier: 17544749

GI number: 17544749

Start: 35476

End: 37005

Strand: Direct

Name: mocR [H]

Synonym: RSc0030

Alternate gene names: 17544749

Gene position: 35476-37005 (Clockwise)

Preceding gene: 17544742

Following gene: 17544753

Centisome position: 0.95

GC content: 72.48

Gene sequence:

>1530_bases
ATGGCAGAACATTCCCCCGCCCATCGCGCCAGCATGCTGGTGGACTACCTGCAGCGCCGCTTCGACCGTGCCGGCCCCGG
CGGCGAGCCCGACCACCGCCGCCTCTACCGCATGCTGCAGGAAGGCATCCTGCGCGACGAGCTGCAGCCCGGCACGCGCC
TGCCCTCCTCGCGGCAGCTGGCGGCGGAGCTGGGCATCGCGCGCAACACCGTGATCCATGTCTACGAGCAACTGGGCGTG
GAGGGCTATGTGTCGGCGGGCGTGGGCAGCGGCACCTTTGTCGCCGATACCGTGCCGGACCGGCTCGATGCCGCGCCGCC
GCCGGCCGCCGCGCCCGTCAGCATCAGCGAAGCGGCGATGCCCGCGGCGCCCATGCTGTCTTCGCGCGGCCGGGCGCTGG
TGCGCGATGCCGGTGCGAGCTCGCGCCAATGGGGCGCCTTCATGCCGGGCGTGCCCGAGGTGCGGATGTTTCCGGCGCGG
ACCTGGTCGCGGCTGCACAACCGGCTGCTGCGCAAGCCGTCGCCGGCGCTGCTGACGTACCCGGTGGGCGCCGGCTACCT
GCCGCTGCGCACGGCGCTGGCCGACTACCTGCGCACCGCGCGCGGCGTGCGCTGCGAGCCGGAGCAGATCATCATCACCG
CCGGCATTCACCCGTCGCTGCAGCTGATCGCGCAGTTGCTGTGCGACGCCGGCGACAGCGCGTGGATCGAAGACCCCGGC
TACTGGGGCGTGCGCAGCGTGCTCACCGCGGCCGGCGTGCGCACCGTGCCGCTGCCGGTGGACGACGAGGGCATGCGCTT
CGAGGCCGCCGGACGCCGCCAGCGCGGCAGGCCGCCCAAGCTGATGGTGGTGTCGCCCTCGCACCAGTACCCGCTCGGCT
CGGTGATGAGCCTGGCGCGCCGCCGCCAGCTGCTGGCCACCGCGCAGGCCACCGATGCGTGGATCGTCGAGGACGACTAC
GACAGCGAGTTCCGCTACGGCAGCCGCCCGCTGCCGTCATTGCAGGGGCTGGACGAGGGCGGGCGCGTGCTCTACATGGG
CACTTTCTCCAAGGTGCTGTTCCCCAGCCTGCGCATCGGCTACCTGGTGGTGCCGCCTGCCTTGGCCGAGGCCTTTGCGA
CAGGGCTGTCGGAGATGTTCCGCGGCGGGCAGATCCTGACGCAGGCAGTGCTGGCCGAGTTCATCGCCGAGGGGCATTTC
GTGTCGCACATCCGGCGCATGCGCGGCGTCTATGCCGAGCGGCGCGAAACGCTGCTCGAGGCCATTCGCCGCGAGTTCGG
CGAGGCGCTGCCGGTGCACGACGGCGCGTCCGGCCTGCACCTCGTGCTGGGCCTGCCGCCGGGCACCGACGATGTCGCCG
TGGTGGAAGCGGCGCTGGCGCGCGATGTCGTCACACGGCCGCTGTCGCGCTATTACCAGGATGACGCGCGCCGCCAGCCC
GGGCTGTTGCTTGGCTATGGGCATGTGGAGACTGAGGCGATCGGGGGGCGCTTCGCGGTGCTGGCCGAGGCGATCCGCGC
GGCGGGGTGA

Upstream 100 bases:

>100_bases
AAAAGGTGCGATGCGGGCCAGTGTGGCAGCCATTGGCCCCGTACAATGAGACCCAATCGAGTTTTTCTGATGGAGCCAAT
CCGGCGCCACGCTCCTTGCC

Downstream 100 bases:

>100_bases
GCCGCGTCCGGGCGCAAAAAAAGCCCCGCATGGCGGTAATGCCGTTCAGTTAAGGCAAAAAAGGCCGCTCCGATTGACGT
CGGAGCGGCCTTTTTCCCTG

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MAEHSPAHRASMLVDYLQRRFDRAGPGGEPDHRRLYRMLQEGILRDELQPGTRLPSSRQLAAELGIARNTVIHVYEQLGV
EGYVSAGVGSGTFVADTVPDRLDAAPPPAAAPVSISEAAMPAAPMLSSRGRALVRDAGASSRQWGAFMPGVPEVRMFPAR
TWSRLHNRLLRKPSPALLTYPVGAGYLPLRTALADYLRTARGVRCEPEQIIITAGIHPSLQLIAQLLCDAGDSAWIEDPG
YWGVRSVLTAAGVRTVPLPVDDEGMRFEAAGRRQRGRPPKLMVVSPSHQYPLGSVMSLARRRQLLATAQATDAWIVEDDY
DSEFRYGSRPLPSLQGLDEGGRVLYMGTFSKVLFPSLRIGYLVVPPALAEAFATGLSEMFRGGQILTQAVLAEFIAEGHF
VSHIRRMRGVYAERRETLLEAIRREFGEALPVHDGASGLHLVLGLPPGTDDVAVVEAALARDVVTRPLSRYYQDDARRQP
GLLLGYGHVETEAIGGRFAVLAEAIRAAG

Sequences:

>Translated_509_residues
MAEHSPAHRASMLVDYLQRRFDRAGPGGEPDHRRLYRMLQEGILRDELQPGTRLPSSRQLAAELGIARNTVIHVYEQLGV
EGYVSAGVGSGTFVADTVPDRLDAAPPPAAAPVSISEAAMPAAPMLSSRGRALVRDAGASSRQWGAFMPGVPEVRMFPAR
TWSRLHNRLLRKPSPALLTYPVGAGYLPLRTALADYLRTARGVRCEPEQIIITAGIHPSLQLIAQLLCDAGDSAWIEDPG
YWGVRSVLTAAGVRTVPLPVDDEGMRFEAAGRRQRGRPPKLMVVSPSHQYPLGSVMSLARRRQLLATAQATDAWIVEDDY
DSEFRYGSRPLPSLQGLDEGGRVLYMGTFSKVLFPSLRIGYLVVPPALAEAFATGLSEMFRGGQILTQAVLAEFIAEGHF
VSHIRRMRGVYAERRETLLEAIRREFGEALPVHDGASGLHLVLGLPPGTDDVAVVEAALARDVVTRPLSRYYQDDARRQP
GLLLGYGHVETEAIGGRFAVLAEAIRAAG
>Mature_508_residues
AEHSPAHRASMLVDYLQRRFDRAGPGGEPDHRRLYRMLQEGILRDELQPGTRLPSSRQLAAELGIARNTVIHVYEQLGVE
GYVSAGVGSGTFVADTVPDRLDAAPPPAAAPVSISEAAMPAAPMLSSRGRALVRDAGASSRQWGAFMPGVPEVRMFPART
WSRLHNRLLRKPSPALLTYPVGAGYLPLRTALADYLRTARGVRCEPEQIIITAGIHPSLQLIAQLLCDAGDSAWIEDPGY
WGVRSVLTAAGVRTVPLPVDDEGMRFEAAGRRQRGRPPKLMVVSPSHQYPLGSVMSLARRRQLLATAQATDAWIVEDDYD
SEFRYGSRPLPSLQGLDEGGRVLYMGTFSKVLFPSLRIGYLVVPPALAEAFATGLSEMFRGGQILTQAVLAEFIAEGHFV
SHIRRMRGVYAERRETLLEAIRREFGEALPVHDGASGLHLVLGLPPGTDDVAVVEAALARDVVTRPLSRYYQDDARRQPG
LLLGYGHVETEAIGGRFAVLAEAIRAAG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=379, Percent_Identity=23.4828496042216, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI33469970, Length=379, Percent_Identity=23.4828496042216, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1790797, Length=431, Percent_Identity=29.6983758700696, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1787710, Length=451, Percent_Identity=27.7161862527716, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321236, Length=304, Percent_Identity=24.0131578947368, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55397; Mature: 55266

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHSPAHRASMLVDYLQRRFDRAGPGGEPDHRRLYRMLQEGILRDELQPGTRLPSSRQL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AAELGIARNTVIHVYEQLGVEGYVSAGVGSGTFVADTVPDRLDAAPPPAAAPVSISEAAM
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCHHHCCCCCCCCCCCCHHHHHC
PAAPMLSSRGRALVRDAGASSRQWGAFMPGVPEVRMFPARTWSRLHNRLLRKPSPALLTY
CCCHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCEEEE
PVGAGYLPLRTALADYLRTARGVRCEPEQIIITAGIHPSLQLIAQLLCDAGDSAWIEDPG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCC
YWGVRSVLTAAGVRTVPLPVDDEGMRFEAAGRRQRGRPPKLMVVSPSHQYPLGSVMSLAR
CHHHHHHHHHCCCEEECCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
RRQLLATAQATDAWIVEDDYDSEFRYGSRPLPSLQGLDEGGRVLYMGTFSKVLFPSLRIG
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCC
YLVVPPALAEAFATGLSEMFRGGQILTQAVLAEFIAEGHFVSHIRRMRGVYAERRETLLE
EEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AIRREFGEALPVHDGASGLHLVLGLPPGTDDVAVVEAALARDVVTRPLSRYYQDDARRQP
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLLLGYGHVETEAIGGRFAVLAEAIRAAG
CEEEECCCCCHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AEHSPAHRASMLVDYLQRRFDRAGPGGEPDHRRLYRMLQEGILRDELQPGTRLPSSRQL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AAELGIARNTVIHVYEQLGVEGYVSAGVGSGTFVADTVPDRLDAAPPPAAAPVSISEAAM
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCHHHCCCCCCCCCCCCHHHHHC
PAAPMLSSRGRALVRDAGASSRQWGAFMPGVPEVRMFPARTWSRLHNRLLRKPSPALLTY
CCCHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCEEEE
PVGAGYLPLRTALADYLRTARGVRCEPEQIIITAGIHPSLQLIAQLLCDAGDSAWIEDPG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCC
YWGVRSVLTAAGVRTVPLPVDDEGMRFEAAGRRQRGRPPKLMVVSPSHQYPLGSVMSLAR
CHHHHHHHHHCCCEEECCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
RRQLLATAQATDAWIVEDDYDSEFRYGSRPLPSLQGLDEGGRVLYMGTFSKVLFPSLRIG
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCC
YLVVPPALAEAFATGLSEMFRGGQILTQAVLAEFIAEGHFVSHIRRMRGVYAERRETLLE
EEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AIRREFGEALPVHDGASGLHLVLGLPPGTDDVAVVEAALARDVVTRPLSRYYQDDARRQP
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLLLGYGHVETEAIGGRFAVLAEAIRAAG
CEEEECCCCCHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]