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The map label for this gene is aroA [H]

Identifier: 17232511

GI number: 17232511

Start: 5990851

End: 5992128

Strand: Reverse

Name: aroA [H]

Synonym: all5019

Alternate gene names: 17232511

Gene position: 5992128-5990851 (Counterclockwise)

Preceding gene: 17232512

Following gene: 17232510

Centisome position: 93.43

GC content: 46.09

Gene sequence:

>1278_bases
GTGGATACCATCGCCATCCCTGCTCTGAATCGTCCTGTGGATGCCACAGTAGAGATTCCGGGTTCTAAAAGTATCACTAA
TCGGGCATTGCTTGTTGCGGCTTTAGCGCAAGGCGACTCTACTTTAGAAAATGCCTTATTTAGTGAAGACAGTGAATATT
TTGCTAAATGTGTAGAGCAGTTGGGTATTCCCATCACACTACATCCTCATCTGGCGCAAATCCAAGTTTCAGGTAAGGGC
GGCGACATCCCGGCAAAACAAGCAGATTTGTTTGTGGGTTTAGCGGGTACAGCAGCAAGATTTATCACGGCGTTGGTAGC
ACTTGGTAATGGGGAATATCGCTTAGATGGAGTTCCTCGGATGCGGGAACGTCCAATGGGTGACTTGGTAACGGTGCTAC
AAAACAGTGGCATAACAATTAACTTTGAGGGCAACTCTGGTTTTATGCCCTACACTATTTATGGTCAGCAATTTGCAGGT
GGACATTTTCGCCTCAAAGCCAACCAAACCAGTCAGCAACTTTCCGCCTTGCTGATGATTGCGCCCTACGCCCAACAGGA
TACAACCATTGAGGTTGAGGGTACATTGGTTTCCCAATCTTATGTAAAAATGACTTGTCGCCTGATGGCTGATTTTGGTG
TGGATGTCACCCAAACTGACGACAACCAATTTCATATCAAAGCAGGTCAACGTTACCAAGCTCGACACTATACTATAGAA
CCCGATGCGTCGAATGCTTCTTACTTTTTCGCCGCCGCCGCCGTCACTGGTGGACGAGTGCGGGTGAACCATTTAACTAA
ACAATCTTGCCAAGGTGATATTTTGTGGCTGAATGTTTTAGAACAGATGGGTTGTCAGGTAATTGAGGGTGCAGATTACA
CCGAAGTTATTGGGCCAGAACAATTACAAGGTATCGACATTGATATGAATGATATGTCGGATTTGGTGCAAACATTGGGA
GCGATCGCCCCTTATGCTAGTTCACCTGTTATCATCCGTAATGTAGAACATATCCGCTATAAAGAAACCGAACGCATCCG
CGCCGTCGTCACCGAATTACGTCGTTTAGGTGTGAAAGTTGAAGAATTTGCCGACGGGATGAAAATTGAACCAACCCCCA
TCACCCCAGCCGCTATCGAAACCTACCACGACCATAGAATGGCAATGGCTTTTGCCGTTACAGGCTTAAAAACCCCAGGT
ATTGTGATTCAAGACCCAGGTTGTACAGCCAAGACATTCCCCGACTACTTTACCCGCTTCTTTAAAATGATTGATTAA

Upstream 100 bases:

>100_bases
GGTGTATGAAAAAAACACCAAAAAATATGACTGTTCCAGCAACCTTCATGATATGGGAACATATATAAGTTGTAGCTGAC
CACCCAGATAGAGGTTGAAA

Downstream 100 bases:

>100_bases
TATGATCGTTCGCAGTTGAGTTTAATACAGACCTAACCCCCAACCCCTTCCCTACAAGGGAAGGGGAGTAAGACTCAAAA
CCATACTACACATAAGCGAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MDTIAIPALNRPVDATVEIPGSKSITNRALLVAALAQGDSTLENALFSEDSEYFAKCVEQLGIPITLHPHLAQIQVSGKG
GDIPAKQADLFVGLAGTAARFITALVALGNGEYRLDGVPRMRERPMGDLVTVLQNSGITINFEGNSGFMPYTIYGQQFAG
GHFRLKANQTSQQLSALLMIAPYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVDVTQTDDNQFHIKAGQRYQARHYTIE
PDASNASYFFAAAAVTGGRVRVNHLTKQSCQGDILWLNVLEQMGCQVIEGADYTEVIGPEQLQGIDIDMNDMSDLVQTLG
AIAPYASSPVIIRNVEHIRYKETERIRAVVTELRRLGVKVEEFADGMKIEPTPITPAAIETYHDHRMAMAFAVTGLKTPG
IVIQDPGCTAKTFPDYFTRFFKMID

Sequences:

>Translated_425_residues
MDTIAIPALNRPVDATVEIPGSKSITNRALLVAALAQGDSTLENALFSEDSEYFAKCVEQLGIPITLHPHLAQIQVSGKG
GDIPAKQADLFVGLAGTAARFITALVALGNGEYRLDGVPRMRERPMGDLVTVLQNSGITINFEGNSGFMPYTIYGQQFAG
GHFRLKANQTSQQLSALLMIAPYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVDVTQTDDNQFHIKAGQRYQARHYTIE
PDASNASYFFAAAAVTGGRVRVNHLTKQSCQGDILWLNVLEQMGCQVIEGADYTEVIGPEQLQGIDIDMNDMSDLVQTLG
AIAPYASSPVIIRNVEHIRYKETERIRAVVTELRRLGVKVEEFADGMKIEPTPITPAAIETYHDHRMAMAFAVTGLKTPG
IVIQDPGCTAKTFPDYFTRFFKMID
>Mature_425_residues
MDTIAIPALNRPVDATVEIPGSKSITNRALLVAALAQGDSTLENALFSEDSEYFAKCVEQLGIPITLHPHLAQIQVSGKG
GDIPAKQADLFVGLAGTAARFITALVALGNGEYRLDGVPRMRERPMGDLVTVLQNSGITINFEGNSGFMPYTIYGQQFAG
GHFRLKANQTSQQLSALLMIAPYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVDVTQTDDNQFHIKAGQRYQARHYTIE
PDASNASYFFAAAAVTGGRVRVNHLTKQSCQGDILWLNVLEQMGCQVIEGADYTEVIGPEQLQGIDIDMNDMSDLVQTLG
AIAPYASSPVIIRNVEHIRYKETERIRAVVTELRRLGVKVEEFADGMKIEPTPITPAAIETYHDHRMAMAFAVTGLKTPG
IVIQDPGCTAKTFPDYFTRFFKMID

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=426, Percent_Identity=42.2535211267606, Blast_Score=311, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6320332, Length=462, Percent_Identity=34.6320346320346, Blast_Score=231, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46533; Mature: 46533

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIAIPALNRPVDATVEIPGSKSITNRALLVAALAQGDSTLENALFSEDSEYFAKCVEQ
CCCEECCCCCCCCCCEEECCCCCCCCHHHEEEEEHHCCCHHHHHHHHCCCHHHHHHHHHH
LGIPITLHPHLAQIQVSGKGGDIPAKQADLFVGLAGTAARFITALVALGNGEYRLDGVPR
HCCCEEECCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEECCCCC
MRERPMGDLVTVLQNSGITINFEGNSGFMPYTIYGQQFAGGHFRLKANQTSQQLSALLMI
HHHCCHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHEEEEE
APYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVDVTQTDDNQFHIKAGQRYQARHYTIE
ECCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEECEEEEEC
PDASNASYFFAAAAVTGGRVRVNHLTKQSCQGDILWLNVLEQMGCQVIEGADYTEVIGPE
CCCCCCCEEEEEEEECCCEEEEEEHHHHCCCCCCHHHHHHHHCCCEEECCCCCHHCCCCH
QLQGIDIDMNDMSDLVQTLGAIAPYASSPVIIRNVEHIRYKETERIRAVVTELRRLGVKV
HHCEEECCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCH
EEFADGMKIEPTPITPAAIETYHDHRMAMAFAVTGLKTPGIVIQDPGCTAKTFPDYFTRF
HHHHCCCEECCCCCCHHHHHHHHHHHEEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHH
FKMID
HHHCC
>Mature Secondary Structure
MDTIAIPALNRPVDATVEIPGSKSITNRALLVAALAQGDSTLENALFSEDSEYFAKCVEQ
CCCEECCCCCCCCCCEEECCCCCCCCHHHEEEEEHHCCCHHHHHHHHCCCHHHHHHHHHH
LGIPITLHPHLAQIQVSGKGGDIPAKQADLFVGLAGTAARFITALVALGNGEYRLDGVPR
HCCCEEECCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEECCCCC
MRERPMGDLVTVLQNSGITINFEGNSGFMPYTIYGQQFAGGHFRLKANQTSQQLSALLMI
HHHCCHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHEEEEE
APYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVDVTQTDDNQFHIKAGQRYQARHYTIE
ECCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEECEEEEEC
PDASNASYFFAAAAVTGGRVRVNHLTKQSCQGDILWLNVLEQMGCQVIEGADYTEVIGPE
CCCCCCCEEEEEEEECCCEEEEEEHHHHCCCCCCHHHHHHHHCCCEEECCCCCHHCCCCH
QLQGIDIDMNDMSDLVQTLGAIAPYASSPVIIRNVEHIRYKETERIRAVVTELRRLGVKV
HHCEEECCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCH
EEFADGMKIEPTPITPAAIETYHDHRMAMAFAVTGLKTPGIVIQDPGCTAKTFPDYFTRF
HHHHCCCEECCCCCCHHHHHHHHHHHEEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHH
FKMID
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA