Click here to switch to the map view.

The map label for this gene is qor [H]

Identifier: 17232500

GI number: 17232500

Start: 5979600

End: 5980670

Strand: Reverse

Name: qor [H]

Synonym: all5008

Alternate gene names: 17232500

Gene position: 5980670-5979600 (Counterclockwise)

Preceding gene: 17232501

Following gene: 17232498

Centisome position: 93.25

GC content: 43.32

Gene sequence:

>1071_bases
GTGGTTGGCGCAGAAGTACGCCGAGGATTTGTCATTGTTTGTGTATTTGGGCATTTTTTGGGGATGAAAAGAGAAAGTTA
CAGGAAGTTAATCGCTAAGGGGCTTAGTCAAGATTTTAAATCTGCTGCGGAAATTGTGGAAGTTCCTATTCCGCAAGTTG
GTATTGGTCAGCTTTTAATTGAAAATAAATTTGCGGGGATTAATGGTGGTTTTGATACTTTAGTTTGTCGTGGTGATATT
CCCTATTTTGAGATAATTCCTCCTTTTGATTTGGGGGTGGAGGCGGTGGGAAAGGTTGTGGCTGTGGGTGAAAATGTTAC
AGGTTTTCAGATAGGTGATGCGGTTGTCACTACAGTCCGTGGTAGCGGTTATCGAGAATATCAGGTGATTGATGCAAACT
TAGCGGTGAAGGTGCGGGAAGCTACGCCAGAAGTTTTAACTTTGATGCCTACTGGTGTATCAGCTTTGGTGGCGTTGGAA
CAAGTGGGGGAGATGACAAGTAATGAAGTGGTTTTGGTGACTGCTGCGGCTGGGGGGACTGGTCATATTGCGGTGCAGTT
GGCTAAGTTAGCCGGGAATCATGTGATTGGTACTTGTAGTTCTGAGGCGAAGTCTAAGTTACTCAAAGCATTAGGATGCG
ATCGCATCATTAACTATCGCACAGAAAACCTGGATCAAGTCCTTAAACAAGAATACCCCAAAGGAATTAACTTAATTTTT
GAGTGTGTAGGTAAAGATGTTTTTGATACCTGCGTTGATAACTTAGCCATTCGCGGACGTTTAGTCAGCATTGGTCACAT
TTCCGAATACGGGAAAAATGTAGAACCAGTGACTCAAGCGCGCATTTATCATCAACTGATGTGGAAAGCAGCTTCAGTCA
GGGGTTTTCTCACACCGTACTATCAAGAATATATCCCGGAAGCAGGCGATCGCCTGTTAAATCTTTTTTACAATGGCAAA
CTCCAAGTTAGTGTTGACCCTACGCAGTTCAACGGCTTAGAATCCATTCCTACAGCAGTGGAATACCTGTTAAGTGGTCA
CAATTGTGGCAAAGTAGTTGTGAAGTTTTAA

Upstream 100 bases:

>100_bases
GATAAGGCTTTATTGAGTTGATATGGGAAGTTTTTAAACGCGGAGTGTCGCTATAGACGCTTCGGCTACTCTACGAGAAC
GCTAAGAGCGAACCCGCAGG

Downstream 100 bases:

>100_bases
AAACTAATGACGGGTATCAGAACGCTCAAACTTAGTTTTTACTTTTTGAGCTATGAACACCAGTATTACTGCTAATAAGG
AAGTTACCACAGCCACAGAT

Product: oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MVGAEVRRGFVIVCVFGHFLGMKRESYRKLIAKGLSQDFKSAAEIVEVPIPQVGIGQLLIENKFAGINGGFDTLVCRGDI
PYFEIIPPFDLGVEAVGKVVAVGENVTGFQIGDAVVTTVRGSGYREYQVIDANLAVKVREATPEVLTLMPTGVSALVALE
QVGEMTSNEVVLVTAAAGGTGHIAVQLAKLAGNHVIGTCSSEAKSKLLKALGCDRIINYRTENLDQVLKQEYPKGINLIF
ECVGKDVFDTCVDNLAIRGRLVSIGHISEYGKNVEPVTQARIYHQLMWKAASVRGFLTPYYQEYIPEAGDRLLNLFYNGK
LQVSVDPTQFNGLESIPTAVEYLLSGHNCGKVVVKF

Sequences:

>Translated_356_residues
MVGAEVRRGFVIVCVFGHFLGMKRESYRKLIAKGLSQDFKSAAEIVEVPIPQVGIGQLLIENKFAGINGGFDTLVCRGDI
PYFEIIPPFDLGVEAVGKVVAVGENVTGFQIGDAVVTTVRGSGYREYQVIDANLAVKVREATPEVLTLMPTGVSALVALE
QVGEMTSNEVVLVTAAAGGTGHIAVQLAKLAGNHVIGTCSSEAKSKLLKALGCDRIINYRTENLDQVLKQEYPKGINLIF
ECVGKDVFDTCVDNLAIRGRLVSIGHISEYGKNVEPVTQARIYHQLMWKAASVRGFLTPYYQEYIPEAGDRLLNLFYNGK
LQVSVDPTQFNGLESIPTAVEYLLSGHNCGKVVVKF
>Mature_356_residues
MVGAEVRRGFVIVCVFGHFLGMKRESYRKLIAKGLSQDFKSAAEIVEVPIPQVGIGQLLIENKFAGINGGFDTLVCRGDI
PYFEIIPPFDLGVEAVGKVVAVGENVTGFQIGDAVVTTVRGSGYREYQVIDANLAVKVREATPEVLTLMPTGVSALVALE
QVGEMTSNEVVLVTAAAGGTGHIAVQLAKLAGNHVIGTCSSEAKSKLLKALGCDRIINYRTENLDQVLKQEYPKGINLIF
ECVGKDVFDTCVDNLAIRGRLVSIGHISEYGKNVEPVTQARIYHQLMWKAASVRGFLTPYYQEYIPEAGDRLLNLFYNGK
LQVSVDPTQFNGLESIPTAVEYLLSGHNCGKVVVKF

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI28557745, Length=369, Percent_Identity=40.650406504065, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI226246682, Length=212, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI226246680, Length=212, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI22748929, Length=212, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI226059159, Length=338, Percent_Identity=26.0355029585799, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226059133, Length=338, Percent_Identity=26.0355029585799, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI22538446, Length=233, Percent_Identity=29.1845493562232, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI22538444, Length=233, Percent_Identity=29.1845493562232, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=26.1146496815287, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI226056130, Length=252, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI194239674, Length=229, Percent_Identity=29.2576419213974, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI13236495, Length=229, Percent_Identity=29.2576419213974, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790485, Length=295, Percent_Identity=31.5254237288136, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI226510941, Length=360, Percent_Identity=25.2777777777778, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI133901710, Length=286, Percent_Identity=29.020979020979, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI133901712, Length=286, Percent_Identity=29.020979020979, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17507255, Length=245, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=229, Percent_Identity=35.3711790393013, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323729, Length=220, Percent_Identity=28.6363636363636, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=210, Percent_Identity=28.0952380952381, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 38629; Mature: 38629

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGAEVRRGFVIVCVFGHFLGMKRESYRKLIAKGLSQDFKSAAEIVEVPIPQVGIGQLLI
CCCCHHHCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHE
ENKFAGINGGFDTLVCRGDIPYFEIIPPFDLGVEAVGKVVAVGENVTGFQIGDAVVTTVR
ECCCCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHCCEEEECCCCCCEEECCCEEEEEC
GSGYREYQVIDANLAVKVREATPEVLTLMPTGVSALVALEQVGEMTSNEVVLVTAAAGGT
CCCCEEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCC
GHIAVQLAKLAGNHVIGTCSSEAKSKLLKALGCDRIINYRTENLDQVLKQEYPKGINLIF
CHHEEEEEHHCCCCEEEECCHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHCCCHHHHHH
ECVGKDVFDTCVDNLAIRGRLVSIGHISEYGKNVEPVTQARIYHQLMWKAASVRGFLTPY
HHHCHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
YQEYIPEAGDRLLNLFYNGKLQVSVDPTQFNGLESIPTAVEYLLSGHNCGKVVVKF
HHHHCCHHHHHHHHHEECCEEEEEECCHHCCCCHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MVGAEVRRGFVIVCVFGHFLGMKRESYRKLIAKGLSQDFKSAAEIVEVPIPQVGIGQLLI
CCCCHHHCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHE
ENKFAGINGGFDTLVCRGDIPYFEIIPPFDLGVEAVGKVVAVGENVTGFQIGDAVVTTVR
ECCCCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHCCEEEECCCCCCEEECCCEEEEEC
GSGYREYQVIDANLAVKVREATPEVLTLMPTGVSALVALEQVGEMTSNEVVLVTAAAGGT
CCCCEEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCC
GHIAVQLAKLAGNHVIGTCSSEAKSKLLKALGCDRIINYRTENLDQVLKQEYPKGINLIF
CHHEEEEEHHCCCCEEEECCHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHCCCHHHHHH
ECVGKDVFDTCVDNLAIRGRLVSIGHISEYGKNVEPVTQARIYHQLMWKAASVRGFLTPY
HHHCHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
YQEYIPEAGDRLLNLFYNGKLQVSVDPTQFNGLESIPTAVEYLLSGHNCGKVVVKF
HHHHCCHHHHHHHHHEECCEEEEEECCHHCCCCHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]