Click here to switch to the map view.

The map label for this gene is holB [H]

Identifier: 17232197

GI number: 17232197

Start: 5610552

End: 5611514

Strand: Reverse

Name: holB [H]

Synonym: all4705

Alternate gene names: 17232197

Gene position: 5611514-5610552 (Counterclockwise)

Preceding gene: 17232200

Following gene: 17232196

Centisome position: 87.49

GC content: 44.13

Gene sequence:

>963_bases
ATGACCAATAACCCATTTGCACCACTGGTAGGACAAAAGCAAGCTATTGAGCTACTAACTCAGGCTGTTAAGCAAAACCG
AGTCGCCCCGGCTTATCTATTTGCGGGGCCAGATGGTGTAGGACGGAGTTTAGCGGCGCGTTGCTTTGTAGAGTTGTTAT
TTGCATCTGTTGTGGAAGCGCGACTTCTCCCATCTCTACAACAGCGTTTGCGTCAAGGTAATCACCCTGATTTACTCTGG
GTACAGCCGACTTATCAATACCAAGGACAAAGATTCACAGCCGCCCAAGCAGCAGAAAAGAAACTCAAGCGCAAAGCACC
GCCTTTAATTCGTTTAGAACAAATTCGAGAAATTACCGAATTTCTCGGCCGTCCTCCCTTAGAAGCACCAAGGAATGTGG
TGGTGTTGGAGGAGGCACAAACAATGGCGGAACCAGCAGCAAATGCCTTGTTGAAGACTTTAGAAGAACCAGGACAAGCT
ACCATAATTTTGATTACGCCTTCTCCTGAGTCCGTATTGCCGACTTTGGTGTCACGCTGTCAACGTATTCCCTTTTACAG
CTTAGATACAAAATCTTTGACTCAAGTACTGACACAAACAGGGAATCAAGAAGTTTTACAGCACCCAGCAGTGTTGAGTT
TAGCATCTGGCAGTCCGGGGAGTGCGATCGCCTCTTATGAACAATTACAAATTATTCCCCCTGACTTACTGCAAGATTTA
ACAACAGCACCAAAATCTCAACGTCACGCGTTGGAATTAGCGAAAAGAATCGACAAGGATTTAGAGACGGAAGCACAATT
ATGGTTAGTTGATTATTTACAGCAATCTTACTGGCAAAAGCGGCATCAACCAGGGATTATCAGTCAATTAGAAAAAGCTC
GTAAATACCTACTTGTCTATGCTCAACCGCGTCTTGTGTGGGAATGTACTTTATTATCTGTATATCAGGAATTTAATATC
TAA

Upstream 100 bases:

>100_bases
AATTTTAATTATTTAAGTTACACAATCCATCATGAGATCTTTTGACAGTTAACAGCCCTGATGAGTAGTTATGCAATTTA
GACGTGCATTAGCTTAAAGA

Downstream 100 bases:

>100_bases
CTACTGGACAATTGATCCTCAACTGCGATACATCTTTTCTGGAGGAATGCAATTGTACAAAACCCAGTTATAGAAATGAT
GGAAACCGCAACTGCTGATA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEARLLPSLQQRLRQGNHPDLLW
VQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITEFLGRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQA
TIILITPSPESVLPTLVSRCQRIPFYSLDTKSLTQVLTQTGNQEVLQHPAVLSLASGSPGSAIASYEQLQIIPPDLLQDL
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHQPGIISQLEKARKYLLVYAQPRLVWECTLLSVYQEFNI

Sequences:

>Translated_320_residues
MTNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEARLLPSLQQRLRQGNHPDLLW
VQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITEFLGRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQA
TIILITPSPESVLPTLVSRCQRIPFYSLDTKSLTQVLTQTGNQEVLQHPAVLSLASGSPGSAIASYEQLQIIPPDLLQDL
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHQPGIISQLEKARKYLLVYAQPRLVWECTLLSVYQEFNI
>Mature_319_residues
TNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEARLLPSLQQRLRQGNHPDLLWV
QPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITEFLGRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQAT
IILITPSPESVLPTLVSRCQRIPFYSLDTKSLTQVLTQTGNQEVLQHPAVLSLASGSPGSAIASYEQLQIIPPDLLQDLT
TAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHQPGIISQLEKARKYLLVYAQPRLVWECTLLSVYQEFNI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35915; Mature: 35784

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RLLPSLQQRLRQGNHPDLLWVQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITE
HHHHHHHHHHHCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FLGRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQATIILITPSPESVLPTLVSRC
HHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
QRIPFYSLDTKSLTQVLTQTGNQEVLQHPAVLSLASGSPGSAIASYEQLQIIPPDLLQDL
HHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHH
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHQPGIISQLEKARKYLLVY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEE
AQPRLVWECTLLSVYQEFNI
ECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNNPFAPLVGQKQAIELLTQAVKQNRVAPAYLFAGPDGVGRSLAARCFVELLFASVVEA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RLLPSLQQRLRQGNHPDLLWVQPTYQYQGQRFTAAQAAEKKLKRKAPPLIRLEQIREITE
HHHHHHHHHHHCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FLGRPPLEAPRNVVVLEEAQTMAEPAANALLKTLEEPGQATIILITPSPESVLPTLVSRC
HHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
QRIPFYSLDTKSLTQVLTQTGNQEVLQHPAVLSLASGSPGSAIASYEQLQIIPPDLLQDL
HHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHH
TTAPKSQRHALELAKRIDKDLETEAQLWLVDYLQQSYWQKRHQPGIISQLEKARKYLLVY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEE
AQPRLVWECTLLSVYQEFNI
ECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]