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The map label for this gene is nadA [H]

Identifier: 17232165

GI number: 17232165

Start: 5573697

End: 5574671

Strand: Reverse

Name: nadA [H]

Synonym: all4673

Alternate gene names: 17232165

Gene position: 5574671-5573697 (Counterclockwise)

Preceding gene: 17232167

Following gene: 17232163

Centisome position: 86.92

GC content: 42.97

Gene sequence:

>975_bases
GTGTTTACCACTGCCTTTGCTCAACGGGAACAGACTCAACCAGGTGGACTACCACTAGATTTATTTGCCGCTATTGAGAG
TCTGAAAAAAGAACTCAATGCGGTTATTTTGGCGCATTATTATCAAGAGCCGGATATTCAAGATATTGCAGACTTTATAG
GCGATTCATTACAACTAGCTAGAGCCGCAGCTCAGACTAATGCAGATGTGATAGTCTTTGCTGGTGTTCATTTTATGGCA
GAGACAGCCAAGATTCTTAATCCCGAAAAATTGGTACTGTTACCAGATTTAAATGCGGGTTGTTCTTTAGCAGATAGTTG
TCCACCAAAAGAATTTGCCGCTTTTAAAGCAGCACATCCCGATCATTTAGTAGTTTCCTATATTAACTGCTCTGCTGAAA
TTAAAGCTATGAGCGATATTATCTGCACCAGTTCCAACGCCGTGAAAATTGTGCAGCAAATCCCTAAAGAACAGCCGATT
ATTTTTGCTCCTGACAGAAATTTGGGGCGTTATGTGATGGAGCAAACGGGACGGGATTTGGTACTGTGGCAAGGTAGCTG
TTTGGTGCATGAAACCTTTTCTGAGAAGAAGATTGTACAATTAAAAGTCGCTCATCCCCAAGCAGAGGCGATCGCTCACC
CAGAATGTGAAAGTAGTGTCTTGCGTCACGCTAGTTTTATCGGCTCTACAGCAGCCTTACTCCAATACTGTCAAACCAGC
CCCAGTCAAGAATTTATCGTGGCGACTGAGCCAGGAATTATCCACCAAATGCAGAAACTAGCACCTAACAAGCATTTTAT
TCCTGCGCCACCCATAAATAATTGTGCTTGCAATGAATGTCCATTTATGCGGTTAAACACCCTAGAAAAACTCTACTGGG
CAATGAAAAATCGTACTCCGGAAATTACCATGTCGGAAGATATCCGACTCGCGGCTCTGCGACCAATGCAACGAATGTTA
GAGATGAGTAATTAG

Upstream 100 bases:

>100_bases
TTGGACACTATTTAGGGGTATTAACCCAGCATCTACTTTTGGTAAAAACTACTATAATTAAATAACCAGACAAAATTTGT
AATAAAAAGTAACCCTAACT

Downstream 100 bases:

>100_bases
TCAATAAATTCTTATATTTTTTACAAATAAAATGGGGAAATCACGTTTCCCCATTTTCCATATCATCTCTGTTTTCCCAA
TCCTCAAATCTAAAAATTCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MFTTAFAQREQTQPGGLPLDLFAAIESLKKELNAVILAHYYQEPDIQDIADFIGDSLQLARAAAQTNADVIVFAGVHFMA
ETAKILNPEKLVLLPDLNAGCSLADSCPPKEFAAFKAAHPDHLVVSYINCSAEIKAMSDIICTSSNAVKIVQQIPKEQPI
IFAPDRNLGRYVMEQTGRDLVLWQGSCLVHETFSEKKIVQLKVAHPQAEAIAHPECESSVLRHASFIGSTAALLQYCQTS
PSQEFIVATEPGIIHQMQKLAPNKHFIPAPPINNCACNECPFMRLNTLEKLYWAMKNRTPEITMSEDIRLAALRPMQRML
EMSN

Sequences:

>Translated_324_residues
MFTTAFAQREQTQPGGLPLDLFAAIESLKKELNAVILAHYYQEPDIQDIADFIGDSLQLARAAAQTNADVIVFAGVHFMA
ETAKILNPEKLVLLPDLNAGCSLADSCPPKEFAAFKAAHPDHLVVSYINCSAEIKAMSDIICTSSNAVKIVQQIPKEQPI
IFAPDRNLGRYVMEQTGRDLVLWQGSCLVHETFSEKKIVQLKVAHPQAEAIAHPECESSVLRHASFIGSTAALLQYCQTS
PSQEFIVATEPGIIHQMQKLAPNKHFIPAPPINNCACNECPFMRLNTLEKLYWAMKNRTPEITMSEDIRLAALRPMQRML
EMSN
>Mature_324_residues
MFTTAFAQREQTQPGGLPLDLFAAIESLKKELNAVILAHYYQEPDIQDIADFIGDSLQLARAAAQTNADVIVFAGVHFMA
ETAKILNPEKLVLLPDLNAGCSLADSCPPKEFAAFKAAHPDHLVVSYINCSAEIKAMSDIICTSSNAVKIVQQIPKEQPI
IFAPDRNLGRYVMEQTGRDLVLWQGSCLVHETFSEKKIVQLKVAHPQAEAIAHPECESSVLRHASFIGSTAALLQYCQTS
PSQEFIVATEPGIIHQMQKLAPNKHFIPAPPINNCACNECPFMRLNTLEKLYWAMKNRTPEITMSEDIRLAALRPMQRML
EMSN

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=42.5806451612903, Blast_Score=253, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 35901; Mature: 35901

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTTAFAQREQTQPGGLPLDLFAAIESLKKELNAVILAHYYQEPDIQDIADFIGDSLQLA
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHCCHHHHH
RAAAQTNADVIVFAGVHFMAETAKILNPEKLVLLPDLNAGCSLADSCPPKEFAAFKAAHP
HHHHHCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCC
DHLVVSYINCSAEIKAMSDIICTSSNAVKIVQQIPKEQPIIFAPDRNLGRYVMEQTGRDL
CCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCEE
VLWQGSCLVHETFSEKKIVQLKVAHPQAEAIAHPECESSVLRHASFIGSTAALLQYCQTS
EEEECCEEEEECCCCCEEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PSQEFIVATEPGIIHQMQKLAPNKHFIPAPPINNCACNECPFMRLNTLEKLYWAMKNRTP
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EITMSEDIRLAALRPMQRMLEMSN
CEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTTAFAQREQTQPGGLPLDLFAAIESLKKELNAVILAHYYQEPDIQDIADFIGDSLQLA
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHCCHHHHH
RAAAQTNADVIVFAGVHFMAETAKILNPEKLVLLPDLNAGCSLADSCPPKEFAAFKAAHP
HHHHHCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCC
DHLVVSYINCSAEIKAMSDIICTSSNAVKIVQQIPKEQPIIFAPDRNLGRYVMEQTGRDL
CCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCEE
VLWQGSCLVHETFSEKKIVQLKVAHPQAEAIAHPECESSVLRHASFIGSTAALLQYCQTS
EEEECCEEEEECCCCCEEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PSQEFIVATEPGIIHQMQKLAPNKHFIPAPPINNCACNECPFMRLNTLEKLYWAMKNRTP
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EITMSEDIRLAALRPMQRMLEMSN
CEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA