Click here to switch to the map view.

The map label for this gene is nlpI [C]

Identifier: 17232151

GI number: 17232151

Start: 5560273

End: 5560983

Strand: Reverse

Name: nlpI [C]

Synonym: all4659

Alternate gene names: 17232151

Gene position: 5560983-5560273 (Counterclockwise)

Preceding gene: 17232154

Following gene: 17232148

Centisome position: 86.7

GC content: 44.44

Gene sequence:

>711_bases
ATGAACAGTCACTCATTTTTAGCCTCCGGTGATCAGCAGAATAACTGTTACCAATTTATTACTAAAACTAAACTTGACCC
TCAAGAAAATGGGGCTAGGGGTGATGAGTCGGGGTTCGGTGATGGCTACTTACGCTCTTGTGCTTTGAGATCAGCACAAC
AGGGAAATTATAGCGAAGCGATCGCTCTCCTTAACCAATTGATTAACCGCCATCCTGACAACGCGGTTGACTATAACAAC
CGGGGGTTAATCTATTTTCAAAGTGGACGTACCCAAAAGGCGCTACAAGATTACAACACTGCATTACAGTTGAATCCTGA
TTTAGCTAGCGCTTACAACAATCGCGCGAATTATTACGCAGCTTGTGGACAATTAGCATCTGCCCTAGCTGATTATGATC
GTGCTATTGATTTAAATCCTCGTCATGTAAGAGCCTGGATTAATCGCGGCATTACTCTACGCGATTTGGGCGAATATGAC
CAAGCAATTGAGAATTTTGATATTGCCCTGGTTTTTGGTCAGCTAGAGGGACATATCTGGGCTGAACGTGGTAGAACTTA
CCATCTTTGGGGTGATTGGAATTGTGCGATCGCCGACTATCGTCGTGCCGAAAATCAATTACCTTCGTTGCATGGTCGCA
GAGATGTTCCTGGCTACCGTTTGCGGTTACAGATGGAAAATTGGTTAAATGAATTGCTGCCTTCGGCGTAA

Upstream 100 bases:

>100_bases
AGTCTGTATCAGGTGTGCTTGTCTGCAAGAAAATTTCTGAACAAGCTACCACAACAACTCTAATTTAATTTCTCAGACTA
AGCAGCTAAGGTAGGAAAAC

Downstream 100 bases:

>100_bases
TTCACAATTAGTCAATAGTTATTAGTTCTTCTCCCTGCCCCCTGCTTCCTGCCTAATCTGCACTACAACCCTGTATTTAT
AAGCCACTACATCTATAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MNSHSFLASGDQQNNCYQFITKTKLDPQENGARGDESGFGDGYLRSCALRSAQQGNYSEAIALLNQLINRHPDNAVDYNN
RGLIYFQSGRTQKALQDYNTALQLNPDLASAYNNRANYYAACGQLASALADYDRAIDLNPRHVRAWINRGITLRDLGEYD
QAIENFDIALVFGQLEGHIWAERGRTYHLWGDWNCAIADYRRAENQLPSLHGRRDVPGYRLRLQMENWLNELLPSA

Sequences:

>Translated_236_residues
MNSHSFLASGDQQNNCYQFITKTKLDPQENGARGDESGFGDGYLRSCALRSAQQGNYSEAIALLNQLINRHPDNAVDYNN
RGLIYFQSGRTQKALQDYNTALQLNPDLASAYNNRANYYAACGQLASALADYDRAIDLNPRHVRAWINRGITLRDLGEYD
QAIENFDIALVFGQLEGHIWAERGRTYHLWGDWNCAIADYRRAENQLPSLHGRRDVPGYRLRLQMENWLNELLPSA
>Mature_236_residues
MNSHSFLASGDQQNNCYQFITKTKLDPQENGARGDESGFGDGYLRSCALRSAQQGNYSEAIALLNQLINRHPDNAVDYNN
RGLIYFQSGRTQKALQDYNTALQLNPDLASAYNNRANYYAACGQLASALADYDRAIDLNPRHVRAWINRGITLRDLGEYD
QAIENFDIALVFGQLEGHIWAERGRTYHLWGDWNCAIADYRRAENQLPSLHGRRDVPGYRLRLQMENWLNELLPSA

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=168, Percent_Identity=27.3809523809524, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32307150, Length=168, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=168, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=168, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17647755, Length=168, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585827, Length=168, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585829, Length=168, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 26834; Mature: 26834

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHSFLASGDQQNNCYQFITKTKLDPQENGARGDESGFGDGYLRSCALRSAQQGNYSEA
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
IALLNQLINRHPDNAVDYNNRGLIYFQSGRTQKALQDYNTALQLNPDLASAYNNRANYYA
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCEEEECCHHHHHHCCCCHHHH
ACGQLASALADYDRAIDLNPRHVRAWINRGITLRDLGEYDQAIENFDIALVFGQLEGHIW
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEECCCCEEE
AERGRTYHLWGDWNCAIADYRRAENQLPSLHGRRDVPGYRLRLQMENWLNELLPSA
ECCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MNSHSFLASGDQQNNCYQFITKTKLDPQENGARGDESGFGDGYLRSCALRSAQQGNYSEA
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
IALLNQLINRHPDNAVDYNNRGLIYFQSGRTQKALQDYNTALQLNPDLASAYNNRANYYA
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCEEEECCHHHHHHCCCCHHHH
ACGQLASALADYDRAIDLNPRHVRAWINRGITLRDLGEYDQAIENFDIALVFGQLEGHIW
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEECCCCEEE
AERGRTYHLWGDWNCAIADYRRAENQLPSLHGRRDVPGYRLRLQMENWLNELLPSA
ECCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]