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The map label for this gene is yfiK [H]

Identifier: 17232127

GI number: 17232127

Start: 5539239

End: 5539898

Strand: Reverse

Name: yfiK [H]

Synonym: all4635

Alternate gene names: 17232127

Gene position: 5539898-5539239 (Counterclockwise)

Preceding gene: 17232128

Following gene: 17232125

Centisome position: 86.38

GC content: 38.64

Gene sequence:

>660_bases
ATGATTAAAGTCTTATTAGTAGATGATCAAAATCTGATCCGTCAAGGATTAAGAGCATTATTAGAGCTAGAACCTGATAT
AGAAATCGTGGGAGAGGCAGAAAATGGAAAAATCGCTATTGATTTGATTCCACAATTTCATCCAGATGTAGTATTGATGG
ATATGCGAATGCCAATTATGGATGGAGTAGCTGCTACACAAGAAATTCAACAGAATTTCCCTAATGTTAAAGTTCTAGTT
CTGACAACTTTTGATGATGATGAATATGTCAAAGCAGCTTTACAACATGGTGCAATGGGTTATTTACTCAAAGATACACC
CTCAGAAGAATTAGCTGTGGCAATTCGCGCAGTTGAGAAAGGTTACACTCAACTAGGGCCAGGAATAGTCAAGAAACTCT
TAGTGCAGTTTCAGTCTACACCAAACCACACGCCACCTGCGCCGACTCATTTAGCTGATCTTACGCCCAGAGAAAAAGAA
GTTTTACGCTTAATTGCCGCAGGTGCAAATAACCGAGAAATTGCCCAACAACTCTATATTTCTGAGGGGACAGTTAAAAA
TCATGTGACGAATATTTTAAATCGGTTGAATTTGCGCGATCGCACCCAAGCCGCTATCATTGCCAATACCTATTTAAATT
ATCTCAATGAATCTGAATAA

Upstream 100 bases:

>100_bases
TGCGCGATCGCACTCTGGCTTTAGGAGGAAAATTTGCTATCAATAGCGCTGTTGGTGATGGTTGTCAAATTACAGTTGAT
ATTCCCGCAAGCAGATTAAT

Downstream 100 bases:

>100_bases
AAGATAGTAAATTCACTATTATTATCTGATTTCACTAAAACAAATTCAAACATTCCTGTCGAAGAATGCCCTTAGTCACT
TTGATGTTTCTCAAAGATTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIKVLLVDDQNLIRQGLRALLELEPDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIMDGVAATQEIQQNFPNVKVLV
LTTFDDDEYVKAALQHGAMGYLLKDTPSEELAVAIRAVEKGYTQLGPGIVKKLLVQFQSTPNHTPPAPTHLADLTPREKE
VLRLIAAGANNREIAQQLYISEGTVKNHVTNILNRLNLRDRTQAAIIANTYLNYLNESE

Sequences:

>Translated_219_residues
MIKVLLVDDQNLIRQGLRALLELEPDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIMDGVAATQEIQQNFPNVKVLV
LTTFDDDEYVKAALQHGAMGYLLKDTPSEELAVAIRAVEKGYTQLGPGIVKKLLVQFQSTPNHTPPAPTHLADLTPREKE
VLRLIAAGANNREIAQQLYISEGTVKNHVTNILNRLNLRDRTQAAIIANTYLNYLNESE
>Mature_219_residues
MIKVLLVDDQNLIRQGLRALLELEPDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIMDGVAATQEIQQNFPNVKVLV
LTTFDDDEYVKAALQHGAMGYLLKDTPSEELAVAIRAVEKGYTQLGPGIVKKLLVQFQSTPNHTPPAPTHLADLTPREKE
VLRLIAAGANNREIAQQLYISEGTVKNHVTNILNRLNLRDRTQAAIIANTYLNYLNESE

Specific function: Member of the two-component regulatory system yfiJ/yfiK [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=38.3495145631068, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788222, Length=199, Percent_Identity=35.1758793969849, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787473, Length=203, Percent_Identity=35.4679802955665, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=31.5533980582524, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786747, Length=195, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789937, Length=213, Percent_Identity=27.2300469483568, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788712, Length=195, Percent_Identity=24.6153846153846, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788546, Length=219, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=36.697247706422, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87082052, Length=105, Percent_Identity=40, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787277, Length=207, Percent_Identity=28.0193236714976, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24382; Mature: 24382

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVLLVDDQNLIRQGLRALLELEPDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIM
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEEEECCCCHH
DGVAATQEIQQNFPNVKVLVLTTFDDDEYVKAALQHGAMGYLLKDTPSEELAVAIRAVEK
HHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
GYTQLGPGIVKKLLVQFQSTPNHTPPAPTHLADLTPREKEVLRLIAAGANNREIAQQLYI
CHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
SEGTVKNHVTNILNRLNLRDRTQAAIIANTYLNYLNESE
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIKVLLVDDQNLIRQGLRALLELEPDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIM
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEEEECCCCHH
DGVAATQEIQQNFPNVKVLVLTTFDDDEYVKAALQHGAMGYLLKDTPSEELAVAIRAVEK
HHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
GYTQLGPGIVKKLLVQFQSTPNHTPPAPTHLADLTPREKEVLRLIAAGANNREIAQQLYI
CHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
SEGTVKNHVTNILNRLNLRDRTQAAIIANTYLNYLNESE
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]