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The map label for this gene is nlpI [C]

Identifier: 17231874

GI number: 17231874

Start: 5252152

End: 5253087

Strand: Reverse

Name: nlpI [C]

Synonym: all4382

Alternate gene names: 17231874

Gene position: 5253087-5252152 (Counterclockwise)

Preceding gene: 17231876

Following gene: 17231873

Centisome position: 81.9

GC content: 40.38

Gene sequence:

>936_bases
ATGAGACTACCATTCTATAAATATCGCATAACAGCGTTGCTGAGTTTGATATTACTAGGTGAATGCTTGACACCAGCCAG
AGCAACTATCCCCATCATCCCCAAATTATTAGCACAATATAGTCTTCCTACAGCCCCTACCTTATTAAATCAGGGATTAC
AGGCAATCCAAGCCGGTAGGCTCCAAGATGCGATCGCTGCTTTCCAGTCAGCCATTCAGTTAGATCCTAACCTAGCCGCA
GCCCACTACAATCTCGGTTTAGCACTGCGACAAACTGGACAATTACAACCAGCCGCCGACGCATTTTATCGCGCTACTCA
AAGTGACCCCAATTTTGCTTTAGCCTTTGCTAATTTGGGCGGCTCATTATTGGAAGGCAATAATTTACAACAAGCCAATG
ACTATTTGCAACGTGCATTGGAATTAGAACCAAGGTTGGGTTTTGCACATTATAACTTGGGGTTAGTCAGACAGCAGCAA
CAAAATTGGGAAGGAGCGATCGCCTCATTTCAAAAAGCAGTAGAGTTGAGTAAAAATGCACCGGAACCTCATTATTATCT
AGGGATTTCTTATTTACAACAAGGTAAATTAAATGAAGCTAAAAATGCTTTCAATCAAGCGATAAAAATCAACCCGCGAT
ATTCCGAAGCTTATTATAATCTGGGCGTTGTCTTATTTAATCAAGGCCAACCCCAAGAAGCATTAACAGCCTTTAGAAAG
TCAGCCGAAGCTAATCCTAATTATCCCAATGCTTATTACGGTGCAGGATTAGTTTTTACCCAATTAAATCAATATGGTGA
AGCAGCAAAAGTATTTAATCACGCCAAGAATTTATATAGTACCCAAGGGAATCCCCAATGGGCAAAAAATGCCGAACAAT
TGTTACAACAAGTACAAAATTTAAATTCTCAACCACGCGGAGGTAAGAATAATTAA

Upstream 100 bases:

>100_bases
AAACTTTAATGCAGAATCTAGAATTTTTGTTAAAACGTAATTTTGAATGTCAGTTTATTTGAAGTAAAGATAACGCAAAT
TGTTGTGAGTTAGCCCATCA

Downstream 100 bases:

>100_bases
CCTACGGTAAAAATGAGATATGGGGTGAATTAATTATTGTCGTCTCCAACTAACCCCTATCCACATGAACAAGAAACTCA
AAAAGCGTACCAAGAGTAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRLPFYKYRITALLSLILLGECLTPARATIPIIPKLLAQYSLPTAPTLLNQGLQAIQAGRLQDAIAAFQSAIQLDPNLAA
AHYNLGLALRQTGQLQPAADAFYRATQSDPNFALAFANLGGSLLEGNNLQQANDYLQRALELEPRLGFAHYNLGLVRQQQ
QNWEGAIASFQKAVELSKNAPEPHYYLGISYLQQGKLNEAKNAFNQAIKINPRYSEAYYNLGVVLFNQGQPQEALTAFRK
SAEANPNYPNAYYGAGLVFTQLNQYGEAAKVFNHAKNLYSTQGNPQWAKNAEQLLQQVQNLNSQPRGGKNN

Sequences:

>Translated_311_residues
MRLPFYKYRITALLSLILLGECLTPARATIPIIPKLLAQYSLPTAPTLLNQGLQAIQAGRLQDAIAAFQSAIQLDPNLAA
AHYNLGLALRQTGQLQPAADAFYRATQSDPNFALAFANLGGSLLEGNNLQQANDYLQRALELEPRLGFAHYNLGLVRQQQ
QNWEGAIASFQKAVELSKNAPEPHYYLGISYLQQGKLNEAKNAFNQAIKINPRYSEAYYNLGVVLFNQGQPQEALTAFRK
SAEANPNYPNAYYGAGLVFTQLNQYGEAAKVFNHAKNLYSTQGNPQWAKNAEQLLQQVQNLNSQPRGGKNN
>Mature_311_residues
MRLPFYKYRITALLSLILLGECLTPARATIPIIPKLLAQYSLPTAPTLLNQGLQAIQAGRLQDAIAAFQSAIQLDPNLAA
AHYNLGLALRQTGQLQPAADAFYRATQSDPNFALAFANLGGSLLEGNNLQQANDYLQRALELEPRLGFAHYNLGLVRQQQ
QNWEGAIASFQKAVELSKNAPEPHYYLGISYLQQGKLNEAKNAFNQAIKINPRYSEAYYNLGVVLFNQGQPQEALTAFRK
SAEANPNYPNAYYGAGLVFTQLNQYGEAAKVFNHAKNLYSTQGNPQWAKNAEQLLQQVQNLNSQPRGGKNN

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=233, Percent_Identity=31.3304721030043, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI32307148, Length=233, Percent_Identity=31.3304721030043, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI118766330, Length=232, Percent_Identity=29.7413793103448, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI118766328, Length=232, Percent_Identity=29.7413793103448, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI83415184, Length=208, Percent_Identity=26.4423076923077, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI301336134, Length=208, Percent_Identity=26.4423076923077, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI22749211, Length=256, Percent_Identity=28.515625, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI167466175, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI167466177, Length=189, Percent_Identity=27.5132275132275, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI33188431, Length=227, Percent_Identity=24.6696035242291, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI170784867, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI33188427, Length=227, Percent_Identity=24.6696035242291, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI33188429, Length=227, Percent_Identity=24.6696035242291, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI189011544, Length=278, Percent_Identity=24.1007194244604, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706671, Length=253, Percent_Identity=25.6916996047431, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI196259772, Length=260, Percent_Identity=25.3846153846154, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI21361204, Length=260, Percent_Identity=25.3846153846154, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI196259770, Length=260, Percent_Identity=25.3846153846154, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI196259776, Length=260, Percent_Identity=25.3846153846154, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI196259774, Length=260, Percent_Identity=25.3846153846154, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=251, Percent_Identity=26.6932270916335, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115532690, Length=251, Percent_Identity=26.6932270916335, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25147174, Length=221, Percent_Identity=24.8868778280543, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6319589, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647755, Length=233, Percent_Identity=30.4721030042918, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585827, Length=233, Percent_Identity=30.4721030042918, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585829, Length=233, Percent_Identity=30.4721030042918, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24647123, Length=211, Percent_Identity=30.3317535545024, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI161076610, Length=171, Percent_Identity=29.8245614035088, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920486, Length=171, Percent_Identity=29.8245614035088, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24659892, Length=183, Percent_Identity=25.1366120218579, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364285, Length=172, Percent_Identity=28.4883720930233, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24581187, Length=172, Percent_Identity=28.4883720930233, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 34369; Mature: 34369

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPFYKYRITALLSLILLGECLTPARATIPIIPKLLAQYSLPTAPTLLNQGLQAIQAGR
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LQDAIAAFQSAIQLDPNLAAAHYNLGLALRQTGQLQPAADAFYRATQSDPNFALAFANLG
HHHHHHHHHHHHHCCCCCEEHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCC
GSLLEGNNLQQANDYLQRALELEPRLGFAHYNLGLVRQQQQNWEGAIASFQKAVELSKNA
CCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PEPHYYLGISYLQQGKLNEAKNAFNQAIKINPRYSEAYYNLGVVLFNQGQPQEALTAFRK
CCCEEEEEHHHHHCCCCHHHHHHHHHHEECCCCHHHHHHCCEEEEECCCCCHHHHHHHHH
SAEANPNYPNAYYGAGLVFTQLNQYGEAAKVFNHAKNLYSTQGNPQWAKNAEQLLQQVQN
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
LNSQPRGGKNN
CCCCCCCCCCC
>Mature Secondary Structure
MRLPFYKYRITALLSLILLGECLTPARATIPIIPKLLAQYSLPTAPTLLNQGLQAIQAGR
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LQDAIAAFQSAIQLDPNLAAAHYNLGLALRQTGQLQPAADAFYRATQSDPNFALAFANLG
HHHHHHHHHHHHHCCCCCEEHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCC
GSLLEGNNLQQANDYLQRALELEPRLGFAHYNLGLVRQQQQNWEGAIASFQKAVELSKNA
CCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PEPHYYLGISYLQQGKLNEAKNAFNQAIKINPRYSEAYYNLGVVLFNQGQPQEALTAFRK
CCCEEEEEHHHHHCCCCHHHHHHHHHHEECCCCHHHHHHCCEEEEECCCCCHHHHHHHHH
SAEANPNYPNAYYGAGLVFTQLNQYGEAAKVFNHAKNLYSTQGNPQWAKNAEQLLQQVQN
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
LNSQPRGGKNN
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]