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The map label for this gene is typA [H]

Identifier: 17231632

GI number: 17231632

Start: 4984481

End: 4986271

Strand: Reverse

Name: typA [H]

Synonym: all4140

Alternate gene names: 17231632

Gene position: 4986271-4984481 (Counterclockwise)

Preceding gene: 17231634

Following gene: 17231631

Centisome position: 77.74

GC content: 47.63

Gene sequence:

>1791_bases
ATGACGCTCCCAATTCGTAACGTCGCCATCATCGCCCACGTTGACCACGGCAAAACCACCCTGGTTGATGCACTCCTCAA
ACAATCCGGCATTTTCCGCGAAGGCGAAGACGTTCCGGATTGCGTTATGGACTCCAACGCTTTAGAGCGAGAACGGGGTA
TTACTATTCTGTCGAAAAATACAGCTGTTCGTTACAAAGAAACACTAATCAATATTGTTGATACCCCTGGACACGCCGAT
TTTGGTGGTGAAGTGGAACGGGTACTCGGCATGGTTGACGGATGTCTGCTGATTGTTGATGCCAATGAAGGCCCCATGCC
TCAAACACGGTTTGTGTTGAAAAAAGCTTTAGAAAAAGGCTTGCGCCCCATCGTTGTCATCAATAAGATTGACCGCGCTA
AAGCCGACCCCCACGTTGCTGTGGATAAGGTGTTGGATCTGTTCTTAGAATTAGGTGCAGACGAAGACCAGTGTGATTTT
ACCTACCTGTTTGCTTCCGGTATGGGCGGTTATGCCAAGGAAAGCATGGAAGCAGAGGCGGTAGATATGCAGCCCCTGTT
TAATGCGATTCTGCAACACGTTCCACCACCAGTAGGCGACATCAACAAGCCCCTACAATTGCAAGTCACAACCCTAGATT
ATTCTGAATATTTGGGACGGATTGTCATTGGCAGAATCCACAATGGTACTATCCGCGCTGGTCAGCAAGCGGCTCTGGTT
ACAGAAAGTGGCTCTATTGTCAAGGGAAAAATCACCAAGTTGATGGGATTTGAAGGGCTGAAGCGGGTAGAGATGGAAGA
AGCAACCGCAGGTTATATTGTTGCGGTGGCTGGTTTTGCTGATGCTTACATCGGTGAAACAATTACTGATCCAACCGAAC
CCCAAGCTTTACCACTAATTAAAGTGGATGAGCCTACCTTACAGATGACCTTCTGGGTAAACGATTCACCCTTTGCTGGT
CAAGAAGGTAAATTGGTGACATCCAGACAAGTACGCGATCGCCTATTCCGCGAACTAGAAACCAACGTTGCTTTACGCGT
TGAAGAAACCGACTCCCCCGACAAATTCCTAGTTTCCGGTCGTGGAGAACTGCACCTGGGTATCTTAATCGAAACCATGC
GCCGCGAAGGTTTTGAGTTCCAAGTATCTCAGCCACAAGTAATTTACCGCGAAATCAACGGTCAACCTTGCGAACCTTAT
GAATTGTTGGTGTTAGACGTTCCTGCTGATTCTGTCGGTAGCTGTATCGAACGTCTAGGACAACGCAAAGGCGAAATGCA
AGATATGCAGCCTGGAAGTGGCGATCGCACCCAGCTAGAGTTTGTCATTCCCGCCCGTGGTTTGATTGGTTTCCGTGGTG
AATTCATGCGGATGACCCGTGGTGAAGGCATCATGAATCACAGCTTCTTAGATTACCGTCAACTCAGTGGTGATATTGAA
GCCCGTAACAAAGGCGTTCTCATCTCCTTTGAAGAAGGCGTTTCTACTTTCTACGCCATGAAGAACGCTGAAGATAGAGG
CTCATTCTTCATTACTCCCGGTACTAAAGTTTACCGAGGCATGATTGTCGGTGAACACAATCGCCCTCAAGACTTAGAAT
TGAATGTCTGCAAAACCAAGCAGTTAACTAACCACCGTGCTGCTGGTGGTGATGAATTGGTTCAGTTGCAAGCACCAATC
GACATGAGTTTAGAGCGTGCATTAGAGTACATCGGCCCCGATGAGTTAGTGGAAGTTACACCCCAATCAATCCGTCTACG
GAAGATGTCGAAGAAATTGGCAAAACGATAA

Upstream 100 bases:

>100_bases
ATTAAAGCTTCTTTACAGAATTCGCAGATCATCCCCAATTCTGTTAAAACAGCCTAGACCTAAATGTAAATTGTAAAATT
CCCCTTAGCTAAAAGCCTCT

Downstream 100 bases:

>100_bases
GTAAAGCGATCGTTTAATTAATTAATTTAAAAAGCCCGCTAATGCGGGCTTTTTATTTTTTATTTATCTTGCATTATGTA
TAGAATGAACTACCTTGTAC

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MTLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDVPDCVMDSNALERERGITILSKNTAVRYKETLINIVDTPGHAD
FGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVVINKIDRAKADPHVAVDKVLDLFLELGADEDQCDF
TYLFASGMGGYAKESMEAEAVDMQPLFNAILQHVPPPVGDINKPLQLQVTTLDYSEYLGRIVIGRIHNGTIRAGQQAALV
TESGSIVKGKITKLMGFEGLKRVEMEEATAGYIVAVAGFADAYIGETITDPTEPQALPLIKVDEPTLQMTFWVNDSPFAG
QEGKLVTSRQVRDRLFRELETNVALRVEETDSPDKFLVSGRGELHLGILIETMRREGFEFQVSQPQVIYREINGQPCEPY
ELLVLDVPADSVGSCIERLGQRKGEMQDMQPGSGDRTQLEFVIPARGLIGFRGEFMRMTRGEGIMNHSFLDYRQLSGDIE
ARNKGVLISFEEGVSTFYAMKNAEDRGSFFITPGTKVYRGMIVGEHNRPQDLELNVCKTKQLTNHRAAGGDELVQLQAPI
DMSLERALEYIGPDELVEVTPQSIRLRKMSKKLAKR

Sequences:

>Translated_596_residues
MTLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDVPDCVMDSNALERERGITILSKNTAVRYKETLINIVDTPGHAD
FGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVVINKIDRAKADPHVAVDKVLDLFLELGADEDQCDF
TYLFASGMGGYAKESMEAEAVDMQPLFNAILQHVPPPVGDINKPLQLQVTTLDYSEYLGRIVIGRIHNGTIRAGQQAALV
TESGSIVKGKITKLMGFEGLKRVEMEEATAGYIVAVAGFADAYIGETITDPTEPQALPLIKVDEPTLQMTFWVNDSPFAG
QEGKLVTSRQVRDRLFRELETNVALRVEETDSPDKFLVSGRGELHLGILIETMRREGFEFQVSQPQVIYREINGQPCEPY
ELLVLDVPADSVGSCIERLGQRKGEMQDMQPGSGDRTQLEFVIPARGLIGFRGEFMRMTRGEGIMNHSFLDYRQLSGDIE
ARNKGVLISFEEGVSTFYAMKNAEDRGSFFITPGTKVYRGMIVGEHNRPQDLELNVCKTKQLTNHRAAGGDELVQLQAPI
DMSLERALEYIGPDELVEVTPQSIRLRKMSKKLAKR
>Mature_595_residues
TLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDVPDCVMDSNALERERGITILSKNTAVRYKETLINIVDTPGHADF
GGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVVINKIDRAKADPHVAVDKVLDLFLELGADEDQCDFT
YLFASGMGGYAKESMEAEAVDMQPLFNAILQHVPPPVGDINKPLQLQVTTLDYSEYLGRIVIGRIHNGTIRAGQQAALVT
ESGSIVKGKITKLMGFEGLKRVEMEEATAGYIVAVAGFADAYIGETITDPTEPQALPLIKVDEPTLQMTFWVNDSPFAGQ
EGKLVTSRQVRDRLFRELETNVALRVEETDSPDKFLVSGRGELHLGILIETMRREGFEFQVSQPQVIYREINGQPCEPYE
LLVLDVPADSVGSCIERLGQRKGEMQDMQPGSGDRTQLEFVIPARGLIGFRGEFMRMTRGEGIMNHSFLDYRQLSGDIEA
RNKGVLISFEEGVSTFYAMKNAEDRGSFFITPGTKVYRGMIVGEHNRPQDLELNVCKTKQLTNHRAAGGDELVQLQAPID
MSLERALEYIGPDELVEVTPQSIRLRKMSKKLAKR

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=312, Percent_Identity=32.0512820512821, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI94966754, Length=160, Percent_Identity=41.875, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=42.0689655172414, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=37.9310344827586, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI34147630, Length=281, Percent_Identity=31.6725978647687, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI25306287, Length=460, Percent_Identity=26.304347826087, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI19923640, Length=142, Percent_Identity=40.8450704225352, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI25306283, Length=142, Percent_Identity=40.8450704225352, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310132016, Length=113, Percent_Identity=43.3628318584071, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310110807, Length=113, Percent_Identity=43.3628318584071, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310123363, Length=113, Percent_Identity=43.3628318584071, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI217272894, Length=134, Percent_Identity=41.7910447761194, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI217272892, Length=134, Percent_Identity=41.7910447761194, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI94966752, Length=156, Percent_Identity=31.4102564102564, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI48994988, Length=589, Percent_Identity=53.9898132427844, Blast_Score=631, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=499, Percent_Identity=28.8577154308617, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789738, Length=174, Percent_Identity=36.7816091954023, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=32.4137931034483, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790412, Length=279, Percent_Identity=28.3154121863799, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789737, Length=279, Percent_Identity=28.3154121863799, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17557151, Length=285, Percent_Identity=32.6315789473684, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI71988811, Length=132, Percent_Identity=40.1515151515151, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=132, Percent_Identity=40.1515151515151, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=40.8450704225352, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17506493, Length=174, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=144, Percent_Identity=43.0555555555556, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=38.0597014925373, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17556456, Length=271, Percent_Identity=28.7822878228782, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323320, Length=506, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324707, Length=203, Percent_Identity=36.9458128078818, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=203, Percent_Identity=36.9458128078818, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324761, Length=272, Percent_Identity=29.7794117647059, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=40.5405405405405, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=149, Percent_Identity=38.255033557047, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=38.7323943661972, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324550, Length=295, Percent_Identity=24.0677966101695, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706572, Length=487, Percent_Identity=26.4887063655031, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28574573, Length=137, Percent_Identity=41.6058394160584, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24582462, Length=139, Percent_Identity=43.8848920863309, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24585711, Length=151, Percent_Identity=39.7350993377483, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24585713, Length=151, Percent_Identity=39.7350993377483, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24585709, Length=151, Percent_Identity=39.7350993377483, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363316, Length=272, Percent_Identity=30.5147058823529, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17864358, Length=272, Percent_Identity=30.5147058823529, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=41.044776119403, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19921738, Length=246, Percent_Identity=30.4878048780488, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221458488, Length=144, Percent_Identity=39.5833333333333, Blast_Score=84, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66107; Mature: 65976

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDVPDCVMDSNALERERGITILSKN
CCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHCCEEEEECC
TAVRYKETLINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKG
CCCEEHHHHHEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHC
LRPIVVINKIDRAKADPHVAVDKVLDLFLELGADEDQCDFTYLFASGMGGYAKESMEAEA
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCHH
VDMQPLFNAILQHVPPPVGDINKPLQLQVTTLDYSEYLGRIVIGRIHNGTIRAGQQAALV
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHCEEEEEEECCCEECCCCCEEEE
TESGSIVKGKITKLMGFEGLKRVEMEEATAGYIVAVAGFADAYIGETITDPTEPQALPLI
ECCCCEEEHHHHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHCCCCCCCCCCCCCEEEE
KVDEPTLQMTFWVNDSPFAGQEGKLVTSRQVRDRLFRELETNVALRVEETDSPDKFLVSG
EECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEC
RGELHLGILIETMRREGFEFQVSQPQVIYREINGQPCEPYELLVLDVPADSVGSCIERLG
CCCEEEHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHH
QRKGEMQDMQPGSGDRTQLEFVIPARGLIGFRGEFMRMTRGEGIMNHSFLDYRQLSGDIE
HCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHCCCCE
ARNKGVLISFEEGVSTFYAMKNAEDRGSFFITPGTKVYRGMIVGEHNRPQDLELNVCKTK
ECCCCEEEEEHHCCHHHHHCCCCCCCCCEEECCCHHHEEEEEEECCCCCCCCEEEEECCH
QLTNHRAAGGDELVQLQAPIDMSLERALEYIGPDELVEVTPQSIRLRKMSKKLAKR
HHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDVPDCVMDSNALERERGITILSKN
CCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHCCEEEEECC
TAVRYKETLINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKG
CCCEEHHHHHEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHC
LRPIVVINKIDRAKADPHVAVDKVLDLFLELGADEDQCDFTYLFASGMGGYAKESMEAEA
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCHH
VDMQPLFNAILQHVPPPVGDINKPLQLQVTTLDYSEYLGRIVIGRIHNGTIRAGQQAALV
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHCEEEEEEECCCEECCCCCEEEE
TESGSIVKGKITKLMGFEGLKRVEMEEATAGYIVAVAGFADAYIGETITDPTEPQALPLI
ECCCCEEEHHHHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHCCCCCCCCCCCCCEEEE
KVDEPTLQMTFWVNDSPFAGQEGKLVTSRQVRDRLFRELETNVALRVEETDSPDKFLVSG
EECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEC
RGELHLGILIETMRREGFEFQVSQPQVIYREINGQPCEPYELLVLDVPADSVGSCIERLG
CCCEEEHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHH
QRKGEMQDMQPGSGDRTQLEFVIPARGLIGFRGEFMRMTRGEGIMNHSFLDYRQLSGDIE
HCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHCCCCE
ARNKGVLISFEEGVSTFYAMKNAEDRGSFFITPGTKVYRGMIVGEHNRPQDLELNVCKTK
ECCCCEEEEEHHCCHHHHHCCCCCCCCCEEECCCHHHEEEEEEECCCCCCCCEEEEECCH
QLTNHRAAGGDELVQLQAPIDMSLERALEYIGPDELVEVTPQSIRLRKMSKKLAKR
HHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]