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The map label for this gene is lrrA [H]

Identifier: 17231591

GI number: 17231591

Start: 4939577

End: 4940470

Strand: Direct

Name: lrrA [H]

Synonym: alr4099

Alternate gene names: 17231591

Gene position: 4939577-4940470 (Clockwise)

Preceding gene: 17231587

Following gene: 17231592

Centisome position: 77.02

GC content: 39.15

Gene sequence:

>894_bases
ATGAAAATTTCCCAACTTCGCGCTGTAGTTGCAGTGGCAGAGCGTGGTAATTTTAGTGAAGCGGCTTTAGAATTACAGCT
GACACAGCCGGCGGTTAGTCATGCGATCGCTACCTTGGAAGAAGAATTGGGTATTCCTTTATTTGCTAGAGGTCGTCATG
GCGCTGTATTAACACCAGTCGGAGAGCGAATTTTACATCATATTCGCCAAGCAATGCAGCACTTAGAAAAGATACAGGAA
GAAGCCAGCACCCACAAATGTTTACATGGTGGTCATGTAAGAGTTGCAGCTTTTCGTTGTGTAGCAACTCATCTATTACC
AAAAGCGATCGCTCAATTTCATAACCAATTTCCCGAAGTTGCTGTCACAATCATCGAATGTCTTTCTGATCTTGATGTAG
AACAGTGTTTGCGTGAAGGTCGTGCTGATATAGGTGTCACTTCTTTACCCACTAGTGATGAATTTACAACATGGGAAATT
CTCAGAGATGAATATATTGCTTTACTACCACCGAAAGCTAAAGTTAATAGTTGTCAATTTACTTGGGAAGATATTGCTAG
ATACTCACCAGTAATAGTGTCTCATTCAGCTTCTGAAAAATCCCTTAATCAAAACCTCAAACAGTTAGCACCTTTTATCA
ACACCACCAGTCATATTCCAGAAGAATCGATGATTGTTAACATGGTACATCAAGGATTAACAGCAGCAATTTTGCCTTAT
TTAGCAGCAATACCAATTCCCCCAGGCGTACAAGTTCATAGTCTACCAAAACCTATAGAAAAAGTAATTTCTGTAGCTGT
CAGTCCTCATTCCCTAAATATTCCGGCTGTATTTAAATTATTAGAAATGCTTAAGAATTTTGATTTTCCTACTTTAGCCA
AATGTCCTTTTTAA

Upstream 100 bases:

>100_bases
CTCAGTAATTAAATATGGTTCTTAGAAATCCAAGATACTCCGGACTTTCGTAATTAGTCATCACCAATTATTTATTAAAA
ATTGAACTGTTTAATTCCCT

Downstream 100 bases:

>100_bases
TTTGTAATTAACAATTATAAATGACTTCTCTAAGAGGTTGTTTTAAAAATGGTAAAATGTGACTTTAATAACTTGCTGAT
CCCCCCTAACCCCCCTTAGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKISQLRAVVAVAERGNFSEAALELQLTQPAVSHAIATLEEELGIPLFARGRHGAVLTPVGERILHHIRQAMQHLEKIQE
EASTHKCLHGGHVRVAAFRCVATHLLPKAIAQFHNQFPEVAVTIIECLSDLDVEQCLREGRADIGVTSLPTSDEFTTWEI
LRDEYIALLPPKAKVNSCQFTWEDIARYSPVIVSHSASEKSLNQNLKQLAPFINTTSHIPEESMIVNMVHQGLTAAILPY
LAAIPIPPGVQVHSLPKPIEKVISVAVSPHSLNIPAVFKLLEMLKNFDFPTLAKCPF

Sequences:

>Translated_297_residues
MKISQLRAVVAVAERGNFSEAALELQLTQPAVSHAIATLEEELGIPLFARGRHGAVLTPVGERILHHIRQAMQHLEKIQE
EASTHKCLHGGHVRVAAFRCVATHLLPKAIAQFHNQFPEVAVTIIECLSDLDVEQCLREGRADIGVTSLPTSDEFTTWEI
LRDEYIALLPPKAKVNSCQFTWEDIARYSPVIVSHSASEKSLNQNLKQLAPFINTTSHIPEESMIVNMVHQGLTAAILPY
LAAIPIPPGVQVHSLPKPIEKVISVAVSPHSLNIPAVFKLLEMLKNFDFPTLAKCPF
>Mature_297_residues
MKISQLRAVVAVAERGNFSEAALELQLTQPAVSHAIATLEEELGIPLFARGRHGAVLTPVGERILHHIRQAMQHLEKIQE
EASTHKCLHGGHVRVAAFRCVATHLLPKAIAQFHNQFPEVAVTIIECLSDLDVEQCLREGRADIGVTSLPTSDEFTTWEI
LRDEYIALLPPKAKVNSCQFTWEDIARYSPVIVSHSASEKSLNQNLKQLAPFINTTSHIPEESMIVNMVHQGLTAAILPY
LAAIPIPPGVQVHSLPKPIEKVISVAVSPHSLNIPAVFKLLEMLKNFDFPTLAKCPF

Specific function: Could Be The Regulator Of The Abg Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=175, Percent_Identity=32, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081904, Length=171, Percent_Identity=32.1637426900585, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=294, Percent_Identity=24.8299319727891, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788748, Length=250, Percent_Identity=25.2, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787530, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788887, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=31.2056737588652, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=236, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787128, Length=135, Percent_Identity=28.8888888888889, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=164, Percent_Identity=29.2682926829268, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=25.6, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=121, Percent_Identity=31.404958677686, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790399, Length=154, Percent_Identity=27.9220779220779, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32759; Mature: 32759

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISQLRAVVAVAERGNFSEAALELQLTQPAVSHAIATLEEELGIPLFARGRHGAVLTPV
CCHHHHHHHHHHHHCCCCCHHHEEEEECCHHHHHHHHHHHHHHCCCEEECCCCCCEECHH
GERILHHIRQAMQHLEKIQEEASTHKCLHGGHVRVAAFRCVATHLLPKAIAQFHNQFPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTIIECLSDLDVEQCLREGRADIGVTSLPTSDEFTTWEILRDEYIALLPPKAKVNSCQF
HHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHEEECCCCCCCCCEE
TWEDIARYSPVIVSHSASEKSLNQNLKQLAPFINTTSHIPEESMIVNMVHQGLTAAILPY
CHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LAAIPIPPGVQVHSLPKPIEKVISVAVSPHSLNIPAVFKLLEMLKNFDFPTLAKCPF
HHHCCCCCCCEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKISQLRAVVAVAERGNFSEAALELQLTQPAVSHAIATLEEELGIPLFARGRHGAVLTPV
CCHHHHHHHHHHHHCCCCCHHHEEEEECCHHHHHHHHHHHHHHCCCEEECCCCCCEECHH
GERILHHIRQAMQHLEKIQEEASTHKCLHGGHVRVAAFRCVATHLLPKAIAQFHNQFPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTIIECLSDLDVEQCLREGRADIGVTSLPTSDEFTTWEILRDEYIALLPPKAKVNSCQF
HHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHEEECCCCCCCCCEE
TWEDIARYSPVIVSHSASEKSLNQNLKQLAPFINTTSHIPEESMIVNMVHQGLTAAILPY
CHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LAAIPIPPGVQVHSLPKPIEKVISVAVSPHSLNIPAVFKLLEMLKNFDFPTLAKCPF
HHHCCCCCCCEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8661945 [H]