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The map label for this gene is ribH [H]

Identifier: 17231485

GI number: 17231485

Start: 4811761

End: 4812333

Strand: Direct

Name: ribH [H]

Synonym: alr3993

Alternate gene names: 17231485

Gene position: 4811761-4812333 (Clockwise)

Preceding gene: 17231484

Following gene: 17231486

Centisome position: 75.02

GC content: 45.03

Gene sequence:

>573_bases
ATGGCAGTTTTCGAGGGAACTTTTACTCAAACAGAACCTTTGCGTTTAGCGGTAGTGATTGGTCGGTTCAATGACCTTGT
AACCACAAAGCTACTAGCAGGATGTCAAGATTGCTTAAAACGCCACGGTGTAGATCCCGATCCCCACGGGAATCAAGTAG
ACTATGTTTGGGTTCCTGGAAGTTTTGAAGTACCTCTTGTTGCTCGTCAACTAGCTCTTACCCATCGTTATGATGCAATC
ATCTGTCTTGGTGCTGTGATTCGTGGACAAACACCCCATTTTGATTATGTCTCCGCCGAAGTATCCAAAGGCATTGCTGC
TGCTAGTTTCCAGACAGGCGTACCTGTAATTTTTGGGATTTTGACAGTAGATACCATGCAGCAAGCTTTAGAAAGAGCAG
GTATCAAAGCTAATCATGGTTGGGACTATGCCATGAATGCTCTAGAAATGGCTAGCCTTATGCGCCAATTGCGTTCTAAC
GTTACAGATTCTTACTCCCAAACCCAATCCTTACCAGCCGCCTTTCCCAATGCCAGCATTGGTAAATTGACCGCAGAGTC
TGAAGAAGTGTAA

Upstream 100 bases:

>100_bases
TTTTTTCTTGTTTTCCCTACCTAATTGTGTTCTCCTGCTCTTCAATATTTAGAGAAGAAATGTATATTGACAAGAAGTAT
ATTAGATTCCAGGTAGAGTC

Downstream 100 bases:

>100_bases
AAAAGTCAGGACTTACGCATGAAAACGAAAAATCAAGGGTTTGGACAAGGATATAGGGTATATATGTTTAAAACCCCTAC
ACCCTTACACCCTTACACCC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MAVFEGTFTQTEPLRLAVVIGRFNDLVTTKLLAGCQDCLKRHGVDPDPHGNQVDYVWVPGSFEVPLVARQLALTHRYDAI
ICLGAVIRGQTPHFDYVSAEVSKGIAAASFQTGVPVIFGILTVDTMQQALERAGIKANHGWDYAMNALEMASLMRQLRSN
VTDSYSQTQSLPAAFPNASIGKLTAESEEV

Sequences:

>Translated_190_residues
MAVFEGTFTQTEPLRLAVVIGRFNDLVTTKLLAGCQDCLKRHGVDPDPHGNQVDYVWVPGSFEVPLVARQLALTHRYDAI
ICLGAVIRGQTPHFDYVSAEVSKGIAAASFQTGVPVIFGILTVDTMQQALERAGIKANHGWDYAMNALEMASLMRQLRSN
VTDSYSQTQSLPAAFPNASIGKLTAESEEV
>Mature_189_residues
AVFEGTFTQTEPLRLAVVIGRFNDLVTTKLLAGCQDCLKRHGVDPDPHGNQVDYVWVPGSFEVPLVARQLALTHRYDAII
CLGAVIRGQTPHFDYVSAEVSKGIAAASFQTGVPVIFGILTVDTMQQALERAGIKANHGWDYAMNALEMASLMRQLRSNV
TDSYSQTQSLPAAFPNASIGKLTAESEEV

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=146, Percent_Identity=45.2054794520548, Blast_Score=137, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324429, Length=148, Percent_Identity=34.4594594594595, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 20653; Mature: 20522

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFEGTFTQTEPLRLAVVIGRFNDLVTTKLLAGCQDCLKRHGVDPDPHGNQVDYVWVPG
CCEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
SFEVPLVARQLALTHRYDAIICLGAVIRGQTPHFDYVSAEVSKGIAAASFQTGVPVIFGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCCCHHHHHHH
LTVDTMQQALERAGIKANHGWDYAMNALEMASLMRQLRSNVTDSYSQTQSLPAAFPNASI
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCC
GKLTAESEEV
CCCCCCCCCC
>Mature Secondary Structure 
AVFEGTFTQTEPLRLAVVIGRFNDLVTTKLLAGCQDCLKRHGVDPDPHGNQVDYVWVPG
CEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
SFEVPLVARQLALTHRYDAIICLGAVIRGQTPHFDYVSAEVSKGIAAASFQTGVPVIFGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCCCHHHHHHH
LTVDTMQQALERAGIKANHGWDYAMNALEMASLMRQLRSNVTDSYSQTQSLPAAFPNASI
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCC
GKLTAESEEV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA