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The map label for this gene is quiP [H]

Identifier: 17231416

GI number: 17231416

Start: 4731430

End: 4733973

Strand: Reverse

Name: quiP [H]

Synonym: all3924

Alternate gene names: 17231416

Gene position: 4733973-4731430 (Counterclockwise)

Preceding gene: 17231419

Following gene: 17231415

Centisome position: 73.81

GC content: 42.14

Gene sequence:

>2544_bases
ATGGCACAGCACCCAAATATGAAAAGTTTCAGAAAAAATAGTTTGTATCAGGGAATAAAGATTACCGTAATTATGCTAGT
GGTGCTATGTATATTATTGTTGGGATTTTTATTCTATACTGTACGGCGTTCTTTCCCTGTAGAAAATGGAGCGATCGCTT
TATCCTCAATCAAATCTGAAGTTACCATCAAACGCGACCAATGGGGAATCCCCCACATCTACGCCAGCAATTCCCATGAT
TTATTCATGGCTCAGGGCTATATTCATGCTCAAGACCGCTTTTGGCAAATGGACTTTTGGCGGCACATCGGGTCTGGGCG
ACTGGCAGAAATGTTTGGTGCTTCCCAGGTGGAAACTGATAAATATCTACGCACGATGGGCTGGGGAAGGGTAGCGCAGC
AAGAAATCCAGCAGATGGATGCAGTAATGAAGGCTGATTTGCAAGCCTACGCTGATGGTGTCAATGCCTATATCCAAGAG
CATCAAGGTAGCGCCCTGAGTTTAGAATATGCCGTATTGCAATTACTCAATCCTGGTTACAAACCCGAACCCTGGCAAAT
CTTGCACTCCCTGACTTGGGGTAAGGTGATGGCTTACGACTTGGGGCGAAATTTTCAAAGCGAAATTGAACGGACAATTT
TGCTGAAAACTCTCACCCCTGCTCAGGTAGAAGAACTTTTTCCGCCTTATCCCGCAAATTTGCCAGTAATTTTGCCTGAT
TTACAAGCTCAGGCTTTGCCGGAGAAACAACTAATTACAACTGTCATCAAAGAAGTTGGTGAAATTGCTCCTGTCTTAGA
ATCAATCAAAAAACCGATGGTGGCGTTAGAAAAACTCATCGGCCATACAGGAGTAGGAATTGGCTCGAATAACTGGGTAA
TATCTGGTGAACGCACAGCTACAGGTAAGCCGATATTGGCAAATGATCCCCATCTAGCAGTACAAATGCCTTCTATTTGG
TACGAGGTAGCACTACACTGCATAAAACAAACGGATGATTGCCCCTACAACGTGAGCGGGTTTTCTTTTCCTGGTATGCT
GGGCGTGATTGTGGGACATAGCGATCGCATCGCTTGGGGTGTGACAAATACTCAAGGCGATGTTATGGATTTATACATTG
AAAAAATTAATCCCAACAACCCCAACCAATATGAAGTCAATGGCAAATGGGTAGATATGCAGGTTTTGCCAGAGACAATC
AAAGTTGCTGGGAAAGAGTCTATTGTGCAGACAGTTCGTTACACCAGACACGGGCCGATTCTTTCGGATGTTTCACCGAA
TTTAAAACAGTTTAATCAAAAATCAACTGTCAACTTACCACAAAATTATGCTGTGGCTTTGCGGTGGACAGCTTTAGAAC
CATCAAACTTAGCATCTGCAATTACCCAAATAAATCGCGCCCAAAATTGGCAAGATTTCCGCACTGCTGCTAATAAATTT
GATATCGCTGCTCAAAATTTAGTTTACGCTGATATTGAAGGAAATATTGGTTATCAAATGCCAGGAAAATTTCCTATTCG
GAATAAGGGAAATGGACGTTATCCTGTTCCTGGTTGGACAGATGAATATGAATGGCAAGGCTATATTGATTTTGAAAAGT
TACCTCAAAGCTTCAATCCATCATCAGGTTATATTGTCACTGCAAATAATTTAGTCGCCAATCAATATCCTTATGTAATA
ACTACAGACTGGGTTTATGGCTACCGAGCAAAGCGGATTGTAGATATGATTGCCCAGCAAGATAAACAGATTTCGCTGCC
AGATGTACAACAGATACAAGGTGATAATTTCAATTTAAATGCACAGAATATTGTGCCGATACTACAACAAATATCATTTA
ATGATTCCCGGTTGCAAACAGCACAAAAATTATTTCAAAATTGGAACTTACAGCTAGTAACTCAATCATCTGCTGCTGCT
TTATTTGAAGTATTCTGGAAACATTTGTTAGCAGATACATTCCACGAACAACTACCAAAAGAATACTTTCCTGATGGAGG
CGATCGCTGGTATGCTGTCATCGAGAATATTATCCAACAACCTAACAGTAATTGGTGGGATAATCGCCAAACTAGTCAAG
TAGAGAACCGTGACCAAATATTTCGTCAAGCCTTTACAAAAGCTGTAGACGAACTAGAACGCCTCCAAGGTAAAAATCCT
CAATCTTGGAATTGGGGAAAGCTGCACACCATCACTTTTCGTAACGCCACCTTGGGTAAGTCTGGAGTTGCACCAATCGA
AGCTTTATTTAACCGTGGTGCCTTTACTACGTCGGGTAACGGAGAAACCGTCAATGCCAACCGTTGGCGAGCAAATCAAT
CCTTTGAAGTCACAGATATTCCTTCACTGCGGATAATTGTAGATTTAGCAAATCTCGATGACTCAGTAGCTATTCACGCC
CCTGGACAGTCAGGTCATGCCTTCCATCAACACTATGACGACATGATTGAGTCCTGGCGCAAACTTGAATATCATCCAAT
GCTTTGGCAACAGCAGACGGTAACAGCTAACACGTCGGCAAAATTGCAGTTAATGCCCAAATGA

Upstream 100 bases:

>100_bases
CAAAATTATTTATACCTAAGTACAAAACAAAAATTCACGTAAGACATTTTACGAGAGATGAGACGGCAAGCTGTATAATG
TCCCAGTGATTTGATTGACG

Downstream 100 bases:

>100_bases
GTTACTGGATACCTGACTTCTTGAAGAAGTCGATTATCTGACCATAATCATCAAATCTATCTATAGAGCAATGCAAAAAT
AGCATCAACTATTAAATAAA

Product: hypothetical protein

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 847; Mature: 846

Protein sequence:

>847_residues
MAQHPNMKSFRKNSLYQGIKITVIMLVVLCILLLGFLFYTVRRSFPVENGAIALSSIKSEVTIKRDQWGIPHIYASNSHD
LFMAQGYIHAQDRFWQMDFWRHIGSGRLAEMFGASQVETDKYLRTMGWGRVAQQEIQQMDAVMKADLQAYADGVNAYIQE
HQGSALSLEYAVLQLLNPGYKPEPWQILHSLTWGKVMAYDLGRNFQSEIERTILLKTLTPAQVEELFPPYPANLPVILPD
LQAQALPEKQLITTVIKEVGEIAPVLESIKKPMVALEKLIGHTGVGIGSNNWVISGERTATGKPILANDPHLAVQMPSIW
YEVALHCIKQTDDCPYNVSGFSFPGMLGVIVGHSDRIAWGVTNTQGDVMDLYIEKINPNNPNQYEVNGKWVDMQVLPETI
KVAGKESIVQTVRYTRHGPILSDVSPNLKQFNQKSTVNLPQNYAVALRWTALEPSNLASAITQINRAQNWQDFRTAANKF
DIAAQNLVYADIEGNIGYQMPGKFPIRNKGNGRYPVPGWTDEYEWQGYIDFEKLPQSFNPSSGYIVTANNLVANQYPYVI
TTDWVYGYRAKRIVDMIAQQDKQISLPDVQQIQGDNFNLNAQNIVPILQQISFNDSRLQTAQKLFQNWNLQLVTQSSAAA
LFEVFWKHLLADTFHEQLPKEYFPDGGDRWYAVIENIIQQPNSNWWDNRQTSQVENRDQIFRQAFTKAVDELERLQGKNP
QSWNWGKLHTITFRNATLGKSGVAPIEALFNRGAFTTSGNGETVNANRWRANQSFEVTDIPSLRIIVDLANLDDSVAIHA
PGQSGHAFHQHYDDMIESWRKLEYHPMLWQQQTVTANTSAKLQLMPK

Sequences:

>Translated_847_residues
MAQHPNMKSFRKNSLYQGIKITVIMLVVLCILLLGFLFYTVRRSFPVENGAIALSSIKSEVTIKRDQWGIPHIYASNSHD
LFMAQGYIHAQDRFWQMDFWRHIGSGRLAEMFGASQVETDKYLRTMGWGRVAQQEIQQMDAVMKADLQAYADGVNAYIQE
HQGSALSLEYAVLQLLNPGYKPEPWQILHSLTWGKVMAYDLGRNFQSEIERTILLKTLTPAQVEELFPPYPANLPVILPD
LQAQALPEKQLITTVIKEVGEIAPVLESIKKPMVALEKLIGHTGVGIGSNNWVISGERTATGKPILANDPHLAVQMPSIW
YEVALHCIKQTDDCPYNVSGFSFPGMLGVIVGHSDRIAWGVTNTQGDVMDLYIEKINPNNPNQYEVNGKWVDMQVLPETI
KVAGKESIVQTVRYTRHGPILSDVSPNLKQFNQKSTVNLPQNYAVALRWTALEPSNLASAITQINRAQNWQDFRTAANKF
DIAAQNLVYADIEGNIGYQMPGKFPIRNKGNGRYPVPGWTDEYEWQGYIDFEKLPQSFNPSSGYIVTANNLVANQYPYVI
TTDWVYGYRAKRIVDMIAQQDKQISLPDVQQIQGDNFNLNAQNIVPILQQISFNDSRLQTAQKLFQNWNLQLVTQSSAAA
LFEVFWKHLLADTFHEQLPKEYFPDGGDRWYAVIENIIQQPNSNWWDNRQTSQVENRDQIFRQAFTKAVDELERLQGKNP
QSWNWGKLHTITFRNATLGKSGVAPIEALFNRGAFTTSGNGETVNANRWRANQSFEVTDIPSLRIIVDLANLDDSVAIHA
PGQSGHAFHQHYDDMIESWRKLEYHPMLWQQQTVTANTSAKLQLMPK
>Mature_846_residues
AQHPNMKSFRKNSLYQGIKITVIMLVVLCILLLGFLFYTVRRSFPVENGAIALSSIKSEVTIKRDQWGIPHIYASNSHDL
FMAQGYIHAQDRFWQMDFWRHIGSGRLAEMFGASQVETDKYLRTMGWGRVAQQEIQQMDAVMKADLQAYADGVNAYIQEH
QGSALSLEYAVLQLLNPGYKPEPWQILHSLTWGKVMAYDLGRNFQSEIERTILLKTLTPAQVEELFPPYPANLPVILPDL
QAQALPEKQLITTVIKEVGEIAPVLESIKKPMVALEKLIGHTGVGIGSNNWVISGERTATGKPILANDPHLAVQMPSIWY
EVALHCIKQTDDCPYNVSGFSFPGMLGVIVGHSDRIAWGVTNTQGDVMDLYIEKINPNNPNQYEVNGKWVDMQVLPETIK
VAGKESIVQTVRYTRHGPILSDVSPNLKQFNQKSTVNLPQNYAVALRWTALEPSNLASAITQINRAQNWQDFRTAANKFD
IAAQNLVYADIEGNIGYQMPGKFPIRNKGNGRYPVPGWTDEYEWQGYIDFEKLPQSFNPSSGYIVTANNLVANQYPYVIT
TDWVYGYRAKRIVDMIAQQDKQISLPDVQQIQGDNFNLNAQNIVPILQQISFNDSRLQTAQKLFQNWNLQLVTQSSAAAL
FEVFWKHLLADTFHEQLPKEYFPDGGDRWYAVIENIIQQPNSNWWDNRQTSQVENRDQIFRQAFTKAVDELERLQGKNPQ
SWNWGKLHTITFRNATLGKSGVAPIEALFNRGAFTTSGNGETVNANRWRANQSFEVTDIPSLRIIVDLANLDDSVAIHAP
GQSGHAFHQHYDDMIESWRKLEYHPMLWQQQTVTANTSAKLQLMPK

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 96099; Mature: 95968

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQHPNMKSFRKNSLYQGIKITVIMLVVLCILLLGFLFYTVRRSFPVENGAIALSSIKSE
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
VTIKRDQWGIPHIYASNSHDLFMAQGYIHAQDRFWQMDFWRHIGSGRLAEMFGASQVETD
EEEECCCCCCCEEEECCCCCEEEECCEEEECHHHHHHHHHHHCCCCHHHHHHCCCCCHHH
KYLRTMGWGRVAQQEIQQMDAVMKADLQAYADGVNAYIQEHQGSALSLEYAVLQLLNPGY
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCC
KPEPWQILHSLTWGKVMAYDLGRNFQSEIERTILLKTLTPAQVEELFPPYPANLPVILPD
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEECC
LQAQALPEKQLITTVIKEVGEIAPVLESIKKPMVALEKLIGHTGVGIGSNNWVISGERTA
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
TGKPILANDPHLAVQMPSIWYEVALHCIKQTDDCPYNVSGFSFPGMLGVIVGHSDRIAWG
CCCCEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEE
VTNTQGDVMDLYIEKINPNNPNQYEVNGKWVDMQVLPETIKVAGKESIVQTVRYTRHGPI
ECCCCCCEEEEEEEECCCCCCCEEEECCEEEEEEECCHHHHHCCHHHHHHHHHHHHCCCC
LSDVSPNLKQFNQKSTVNLPQNYAVALRWTALEPSNLASAITQINRAQNWQDFRTAANKF
HHCCCCCHHHCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DIAAQNLVYADIEGNIGYQMPGKFPIRNKGNGRYPVPGWTDEYEWQGYIDFEKLPQSFNP
CEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHCCCCCCC
SSGYIVTANNLVANQYPYVITTDWVYGYRAKRIVDMIAQQDKQISLPDVQQIQGDNFNLN
CCCEEEEECCEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
AQNIVPILQQISFNDSRLQTAQKLFQNWNLQLVTQSSAAALFEVFWKHLLADTFHEQLPK
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCH
EYFPDGGDRWYAVIENIIQQPNSNWWDNRQTSQVENRDQIFRQAFTKAVDELERLQGKNP
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QSWNWGKLHTITFRNATLGKSGVAPIEALFNRGAFTTSGNGETVNANRWRANQSFEVTDI
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCEEECCCCCEECCCCCCCCCCEEEECC
PSLRIIVDLANLDDSVAIHAPGQSGHAFHQHYDDMIESWRKLEYHPMLWQQQTVTANTSA
CCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
KLQLMPK
EEEECCC
>Mature Secondary Structure 
AQHPNMKSFRKNSLYQGIKITVIMLVVLCILLLGFLFYTVRRSFPVENGAIALSSIKSE
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
VTIKRDQWGIPHIYASNSHDLFMAQGYIHAQDRFWQMDFWRHIGSGRLAEMFGASQVETD
EEEECCCCCCCEEEECCCCCEEEECCEEEECHHHHHHHHHHHCCCCHHHHHHCCCCCHHH
KYLRTMGWGRVAQQEIQQMDAVMKADLQAYADGVNAYIQEHQGSALSLEYAVLQLLNPGY
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCC
KPEPWQILHSLTWGKVMAYDLGRNFQSEIERTILLKTLTPAQVEELFPPYPANLPVILPD
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEECC
LQAQALPEKQLITTVIKEVGEIAPVLESIKKPMVALEKLIGHTGVGIGSNNWVISGERTA
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
TGKPILANDPHLAVQMPSIWYEVALHCIKQTDDCPYNVSGFSFPGMLGVIVGHSDRIAWG
CCCCEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEE
VTNTQGDVMDLYIEKINPNNPNQYEVNGKWVDMQVLPETIKVAGKESIVQTVRYTRHGPI
ECCCCCCEEEEEEEECCCCCCCEEEECCEEEEEEECCHHHHHCCHHHHHHHHHHHHCCCC
LSDVSPNLKQFNQKSTVNLPQNYAVALRWTALEPSNLASAITQINRAQNWQDFRTAANKF
HHCCCCCHHHCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DIAAQNLVYADIEGNIGYQMPGKFPIRNKGNGRYPVPGWTDEYEWQGYIDFEKLPQSFNP
CEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHCCCCCCC
SSGYIVTANNLVANQYPYVITTDWVYGYRAKRIVDMIAQQDKQISLPDVQQIQGDNFNLN
CCCEEEEECCEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCC
AQNIVPILQQISFNDSRLQTAQKLFQNWNLQLVTQSSAAALFEVFWKHLLADTFHEQLPK
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCH
EYFPDGGDRWYAVIENIIQQPNSNWWDNRQTSQVENRDQIFRQAFTKAVDELERLQGKNP
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QSWNWGKLHTITFRNATLGKSGVAPIEALFNRGAFTTSGNGETVNANRWRANQSFEVTDI
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCEEECCCCCEECCCCCCCCCCEEEECC
PSLRIIVDLANLDDSVAIHAPGQSGHAFHQHYDDMIESWRKLEYHPMLWQQQTVTANTSA
CCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
KLQLMPK
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]