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The map label for this gene is coaX

Identifier: 17231388

GI number: 17231388

Start: 4699617

End: 4700447

Strand: Direct

Name: coaX

Synonym: alr3896

Alternate gene names: 17231388

Gene position: 4699617-4700447 (Clockwise)

Preceding gene: 17231382

Following gene: 17231389

Centisome position: 73.27

GC content: 45.61

Gene sequence:

>831_bases
GTGATATCACAGCAGTCTGCAAAACACATAGAAAATCAGTGGTTAGCCTTGGAAATCGGTAATTCCCGGCTACATTGGGC
TTTATTCATGGGCGAATCCCTTGAGTTTACGTGGGATACAGAATATCTACCTGAGTCAGTTATACAGCAGTTAGGTAACG
GTGAGACAAAATTGGAAGTGGGAAGCGAGGAAAAGGAAATTTTCTTTACTTTTTTCCCCCTTCCCCCTGCCCCCTGCCCC
CTACCTCTTTTCATCGCCTCTGTTGTTCCGCAGCAAACTGTTCTTTGGGAAAATTACCTTAATGTTCGCGTAATTACTTT
AGACCAGATACCGCTTAACAATATATATCCTACCTTGGGAATTGACCGGGCTTTGGCTTTGTGGGGTGCGGGGATGAGTT
GGGGTTTTCCGGTGTTGGTGATTGATGCGGGGACGGCGCTAACTTTCACGGCTGCGGATGGTGGAAAAAATTTGGTTGGT
GGGGCAATTTTGCCGGGGGTGGGTTTACAATTTGCGAGTTTAGGTCAACAAACTGGACAATTACCGCAAGTAGAGATGGA
AGCCATCAAGTCTCTACCTCCACGTTTTGCGCTGAATACGACAGAAGCAATCCAAAGCGGTGTGATTTATACCTTAATAG
CGGGAATGAGGGATTTTACGGAAGAGTGGTTGTCTCTATTTCCTGATGGGAAGGTGGCAATTAAAGGAGGCGATCGCATC
TTACTATTAAACTACCTCCAAGCTCTCTATCCTGACCTAGCAGCGCGTTTAATAGTGGAACCAAACCTAATTTTTTGGGG
TATGCAAACAATAGTAGCAGGTGTTGCTTAA

Upstream 100 bases:

>100_bases
CTTTACACAATGAGTATTTATTCCTCTAGTCTTATTGTGACACGGAATATTTGTAAATTTTTATTAAAAAACCTATAGAT
AACTTAAAAAATATAAAAAA

Downstream 100 bases:

>100_bases
CAGAAAATTTAAGGTATTATCATCGCCAGGAAATCATATTAGCCTCTATTACGTACTAGATTGAAATTATTGTCATGTAC
ATGAGGTTTTGAGATGTCGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MISQQSAKHIENQWLALEIGNSRLHWALFMGESLEFTWDTEYLPESVIQQLGNGETKLEVGSEEKEIFFTFFPLPPAPCP
LPLFIASVVPQQTVLWENYLNVRVITLDQIPLNNIYPTLGIDRALALWGAGMSWGFPVLVIDAGTALTFTAADGGKNLVG
GAILPGVGLQFASLGQQTGQLPQVEMEAIKSLPPRFALNTTEAIQSGVIYTLIAGMRDFTEEWLSLFPDGKVAIKGGDRI
LLLNYLQALYPDLAARLIVEPNLIFWGMQTIVAGVA

Sequences:

>Translated_276_residues
MISQQSAKHIENQWLALEIGNSRLHWALFMGESLEFTWDTEYLPESVIQQLGNGETKLEVGSEEKEIFFTFFPLPPAPCP
LPLFIASVVPQQTVLWENYLNVRVITLDQIPLNNIYPTLGIDRALALWGAGMSWGFPVLVIDAGTALTFTAADGGKNLVG
GAILPGVGLQFASLGQQTGQLPQVEMEAIKSLPPRFALNTTEAIQSGVIYTLIAGMRDFTEEWLSLFPDGKVAIKGGDRI
LLLNYLQALYPDLAARLIVEPNLIFWGMQTIVAGVA
>Mature_276_residues
MISQQSAKHIENQWLALEIGNSRLHWALFMGESLEFTWDTEYLPESVIQQLGNGETKLEVGSEEKEIFFTFFPLPPAPCP
LPLFIASVVPQQTVLWENYLNVRVITLDQIPLNNIYPTLGIDRALALWGAGMSWGFPVLVIDAGTALTFTAADGGKNLVG
GAILPGVGLQFASLGQQTGQLPQVEMEAIKSLPPRFALNTTEAIQSGVIYTLIAGMRDFTEEWLSLFPDGKVAIKGGDRI
LLLNYLQALYPDLAARLIVEPNLIFWGMQTIVAGVA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_NOSS1 (Q8YQD7)

Other databases:

- EMBL:   BA000019
- PIR:   AI2292
- RefSeq:   NP_487936.1
- ProteinModelPortal:   Q8YQD7
- STRING:   Q8YQD7
- GeneID:   1107494
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr3896
- NMPDR:   fig|103690.1.peg.4203
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   NYLQALY
- ProtClustDB:   PRK13331
- BioCyc:   NSP103690:ALR3896-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 30272; Mature: 30272

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: ACT_SITE 122-122 BINDING 116-116 BINDING 145-145 BINDING 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISQQSAKHIENQWLALEIGNSRLHWALFMGESLEFTWDTEYLPESVIQQLGNGETKLEV
CCCCHHHHHHHCCEEEEEECCCEEEEEEEECCCEEEEECCHHCCHHHHHHHCCCCEEEEE
GSEEKEIFFTFFPLPPAPCPLPLFIASVVPQQTVLWENYLNVRVITLDQIPLNNIYPTLG
CCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCC
IDRALALWGAGMSWGFPVLVIDAGTALTFTAADGGKNLVGGAILPGVGLQFASLGQQTGQ
HHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCC
LPQVEMEAIKSLPPRFALNTTEAIQSGVIYTLIAGMRDFTEEWLSLFPDGKVAIKGGDRI
CCHHHHHHHHCCCCCEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEE
LLLNYLQALYPDLAARLIVEPNLIFWGMQTIVAGVA
EHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
>Mature Secondary Structure
MISQQSAKHIENQWLALEIGNSRLHWALFMGESLEFTWDTEYLPESVIQQLGNGETKLEV
CCCCHHHHHHHCCEEEEEECCCEEEEEEEECCCEEEEECCHHCCHHHHHHHCCCCEEEEE
GSEEKEIFFTFFPLPPAPCPLPLFIASVVPQQTVLWENYLNVRVITLDQIPLNNIYPTLG
CCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCC
IDRALALWGAGMSWGFPVLVIDAGTALTFTAADGGKNLVGGAILPGVGLQFASLGQQTGQ
HHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCC
LPQVEMEAIKSLPPRFALNTTEAIQSGVIYTLIAGMRDFTEEWLSLFPDGKVAIKGGDRI
CCHHHHHHHHCCCCCEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEE
LLLNYLQALYPDLAARLIVEPNLIFWGMQTIVAGVA
EHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840