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The map label for this gene is grxC [C]

Identifier: 17231352

GI number: 17231352

Start: 4658547

End: 4658819

Strand: Reverse

Name: grxC [C]

Synonym: asl3860

Alternate gene names: 17231352

Gene position: 4658819-4658547 (Counterclockwise)

Preceding gene: 17231353

Following gene: 17231351

Centisome position: 72.64

GC content: 41.76

Gene sequence:

>273_bases
ATGGCTGCCACAGTAGAAATTTACACTTGGAGAACTTGCCCTTTTTGCATTCGAGCAAAAAATTTGCTCAATAACAAGGG
TGTTGAGTTTGTTGAATACAGTATCGATGGTGATGAGGAGGCAAGGGATAAAATGGCTCAGAGAGCCAATGGTAGACGCT
CATTACCACAAATTTTTATCAATGATCGCCATGTGGGTGGTTGTGATGATATCCATGCTCTTGAACGTCAAGGCCAACTT
GATGAGTTATTAGCATCTAGTACTAGCCTCTAG

Upstream 100 bases:

>100_bases
TTCATACCAAGCAGCAAAAGCACAGTTTATAACTACTATTAAGCATCTACCATCAGTACCAAAGTTCTAAAATTAGTTAT
GAGATCATGTTGAGGACATT

Downstream 100 bases:

>100_bases
AAACTTAAGCAACAGGATTACGCTTTTTTCCTCACCACTAATTGTCAATCTGTCAGGATATCGAGGGATAATTTATCTGA
GAATTTCCTGGCGTTGAGGC

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 89

Protein sequence:

>90_residues
MAATVEIYTWRTCPFCIRAKNLLNNKGVEFVEYSIDGDEEARDKMAQRANGRRSLPQIFINDRHVGGCDDIHALERQGQL
DELLASSTSL

Sequences:

>Translated_90_residues
MAATVEIYTWRTCPFCIRAKNLLNNKGVEFVEYSIDGDEEARDKMAQRANGRRSLPQIFINDRHVGGCDDIHALERQGQL
DELLASSTSL
>Mature_89_residues
AATVEIYTWRTCPFCIRAKNLLNNKGVEFVEYSIDGDEEARDKMAQRANGRRSLPQIFINDRHVGGCDDIHALERQGQLD
ELLASSTSL

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaredoxin family [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=56.0975609756098, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10171; Mature: 10039

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATVEIYTWRTCPFCIRAKNLLNNKGVEFVEYSIDGDEEARDKMAQRANGRRSLPQIFI
CCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEE
NDRHVGGCDDIHALERQGQLDELLASSTSL
CCCCCCCCHHHHHHHHCCCHHHHHHHCCCC
>Mature Secondary Structure 
AATVEIYTWRTCPFCIRAKNLLNNKGVEFVEYSIDGDEEARDKMAQRANGRRSLPQIFI
CCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEE
NDRHVGGCDDIHALERQGQLDELLASSTSL
CCCCCCCCHHHHHHHHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]