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The map label for this gene is bcsAI [H]

Identifier: 17231249

GI number: 17231249

Start: 4537835

End: 4539916

Strand: Direct

Name: bcsAI [H]

Synonym: alr3757

Alternate gene names: 17231249

Gene position: 4537835-4539916 (Clockwise)

Preceding gene: 17231248

Following gene: 17231250

Centisome position: 70.75

GC content: 40.15

Gene sequence:

>2082_bases
ATGGCAGTTATTGGATGTCTGGTGCTTCCCAGTGATGTAACAGGACTTGGGAGTCCTGTCTCCGACAAGAATTTTATTAC
CAGTGTCAAAATGACTTCTATTAATCATGATCCAACTTTTTCTGGCAATAGTCGCTCCACCCTCAAAAAAAGAACACTTT
TATTTCGTTACCTCGCAGAAATCAATTTAATTTTTGGTCTGTGGTATTTACAATGGCGCATTACCAACTCCATCAATTTT
GATGCGTTATGGCTCTCGATTCCGTTGTTGCTGGCGGAAATTTATAGCTACCTTGGCGGAGTGATGTTTGTCATTGGCTT
GTGGCGACCTTTAGTCCGACAGATTAAGTCACTTGACCAGTTGACTCCATCTCTACCGCAAACAGATTGGCCAATTGTAG
ATGTCTTTATCACCTGTTACAACGAACCGCCGGAGATGGTCGAACAAACGGCCCAAGCAGCTTTAGCCATAGATTATCCA
CCAACTAAGCTGTATGTTTATGTTTTGGATGATGGTAACTCCCCTGCTATGCGAGCCATGACGGAAAAGTTATGTATTGC
AGATTTACAGTCACCACTACTACAGCAAGAAGCCAACCGCATTGATGCAGAACGCTCACACTTGGTAGAACGTCTGCAAA
AGTTAGAAAGTTTCACCTCTAATATTCAAGTGGCTGAAGAATGGTTGTCAAAATCGTCATCAGTTCCCAACCAGGACAAA
ACCACAGATGAAGTTTTAGCGCAGAGTTTGCAACAGTTTATTCGTTGGTTATCTCCCAAACATCACAGTATTGCTGAACG
CCTCAAAACTGAACGCCAAGTTTTAGCAGGCGCTATTCGCCAAAAAGAACTGGAATTGGTCGAACTCACTAGATTTCGTT
ATATTGCTCGTCCCAAACCTGCGGGTGTACCCCACCATGCGAAAGCAGGAAACCTCAATTACGCAATTTTTTCTGGTGAA
ACTTCGGGAGAATTTATTCTCACTTTAGATGCTGATCATATTCCCAAACCCCAATTTCTCAAGCGGGTTTTGCCATATTT
CTACACATATAATCTGTTTAATGGCAAGTATGAGCAAAACCGCATTGCTTTTGTACAGACACCTCAGGACTTTTATAATA
TTCCTCCCAGTGATCCCTTTGGGCATCGAGCCAGTTTATTTTATGGGCCACTACAACAGGGTAAAGATGGGATGAATGCG
GCCTTTTATACAGGTACTAACGCTATTTTGCGACGTGAGGCCTTAATTAATGTGGGACTACAATATTTTGCCGATGATTT
TACCAAAGATGAAAAACGATTAGATGAATTTCAATTGGTTGGTGGTCTATCTAGCAACAGTATTACAGAAGATATGAATA
CCGCTATGCGTTTGCATGGTGCTGGTTGGAAATCAGTTTATCATCATGAACTTTTGGCAGAAGGTTTAGCACCTGATGAC
CTCAGTTCTACTTTAAAACAAAGACTACGTTGGGCGCAGGGAACAATCCAAGTACTAGTTAAAGAAAACCCACTGAGGAA
ATCAGGACTCACGTTTTGGCAACGTCTGCAATATTTTAAGACGATGTATAGTTATTTTTCCGGTTTTGCTACGCTTATTT
TTATTTCTTGTCCAATTATTTATTTTTTTACAGAAATTGTTCCTGTAAAAACATACGGTACTGATTTCATTCTACACTTT
TTACCCACCTTTATAATCAATCGTCTAACGTTTGTTGTAGCAATATGGGGTATTCCAGCTAGTGAAATCTGGCGTTCTGA
ACAATATGCGATCGCTTTATTTCCCATATTTATTCAAGCTGTTTGGAGTGTATTCACTGGACAGAAGATGAACTTTCAAG
TTACCCCTAAAGAACGGCAATCAGGTATTTATCTGAGCATGATTTGGCCACAATTATTAATCTTCTTTTTAACTATTATA
GGCATATTTTGGAGTCTTTATAGCTTTGCGATTGGTCGTCTCAATCATCCTTGGGTAAACCTGCTCAATAGTTCCTGGGC
TGTCTATAACTTGCTACTCTTATCAGGTATCATTCGTGCATCTGTTTGGCAAATGCCAAAATATGATTCAAAGAAAGTGT
AA

Upstream 100 bases:

>100_bases
GCCATGCAATCACCTTGGTGGCAAGCTGTGGCTCAAGGGGACTCCGGCCGAGGCTTACCGAGAATTGCTAAATCAAAAGT
CAGATTAATTTCTGATAGTT

Downstream 100 bases:

>100_bases
ATATTATTTATTGGTCGTTATTTTACAAACAAAATTGATGTCCGGCAGGGGATATTATCCACAAAAATACTTAATCTCAT
CCAATAATTAAATTTTATTT

Product: cellulose synthase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MAVIGCLVLPSDVTGLGSPVSDKNFITSVKMTSINHDPTFSGNSRSTLKKRTLLFRYLAEINLIFGLWYLQWRITNSINF
DALWLSIPLLLAEIYSYLGGVMFVIGLWRPLVRQIKSLDQLTPSLPQTDWPIVDVFITCYNEPPEMVEQTAQAALAIDYP
PTKLYVYVLDDGNSPAMRAMTEKLCIADLQSPLLQQEANRIDAERSHLVERLQKLESFTSNIQVAEEWLSKSSSVPNQDK
TTDEVLAQSLQQFIRWLSPKHHSIAERLKTERQVLAGAIRQKELELVELTRFRYIARPKPAGVPHHAKAGNLNYAIFSGE
TSGEFILTLDADHIPKPQFLKRVLPYFYTYNLFNGKYEQNRIAFVQTPQDFYNIPPSDPFGHRASLFYGPLQQGKDGMNA
AFYTGTNAILRREALINVGLQYFADDFTKDEKRLDEFQLVGGLSSNSITEDMNTAMRLHGAGWKSVYHHELLAEGLAPDD
LSSTLKQRLRWAQGTIQVLVKENPLRKSGLTFWQRLQYFKTMYSYFSGFATLIFISCPIIYFFTEIVPVKTYGTDFILHF
LPTFIINRLTFVVAIWGIPASEIWRSEQYAIALFPIFIQAVWSVFTGQKMNFQVTPKERQSGIYLSMIWPQLLIFFLTII
GIFWSLYSFAIGRLNHPWVNLLNSSWAVYNLLLLSGIIRASVWQMPKYDSKKV

Sequences:

>Translated_693_residues
MAVIGCLVLPSDVTGLGSPVSDKNFITSVKMTSINHDPTFSGNSRSTLKKRTLLFRYLAEINLIFGLWYLQWRITNSINF
DALWLSIPLLLAEIYSYLGGVMFVIGLWRPLVRQIKSLDQLTPSLPQTDWPIVDVFITCYNEPPEMVEQTAQAALAIDYP
PTKLYVYVLDDGNSPAMRAMTEKLCIADLQSPLLQQEANRIDAERSHLVERLQKLESFTSNIQVAEEWLSKSSSVPNQDK
TTDEVLAQSLQQFIRWLSPKHHSIAERLKTERQVLAGAIRQKELELVELTRFRYIARPKPAGVPHHAKAGNLNYAIFSGE
TSGEFILTLDADHIPKPQFLKRVLPYFYTYNLFNGKYEQNRIAFVQTPQDFYNIPPSDPFGHRASLFYGPLQQGKDGMNA
AFYTGTNAILRREALINVGLQYFADDFTKDEKRLDEFQLVGGLSSNSITEDMNTAMRLHGAGWKSVYHHELLAEGLAPDD
LSSTLKQRLRWAQGTIQVLVKENPLRKSGLTFWQRLQYFKTMYSYFSGFATLIFISCPIIYFFTEIVPVKTYGTDFILHF
LPTFIINRLTFVVAIWGIPASEIWRSEQYAIALFPIFIQAVWSVFTGQKMNFQVTPKERQSGIYLSMIWPQLLIFFLTII
GIFWSLYSFAIGRLNHPWVNLLNSSWAVYNLLLLSGIIRASVWQMPKYDSKKV
>Mature_692_residues
AVIGCLVLPSDVTGLGSPVSDKNFITSVKMTSINHDPTFSGNSRSTLKKRTLLFRYLAEINLIFGLWYLQWRITNSINFD
ALWLSIPLLLAEIYSYLGGVMFVIGLWRPLVRQIKSLDQLTPSLPQTDWPIVDVFITCYNEPPEMVEQTAQAALAIDYPP
TKLYVYVLDDGNSPAMRAMTEKLCIADLQSPLLQQEANRIDAERSHLVERLQKLESFTSNIQVAEEWLSKSSSVPNQDKT
TDEVLAQSLQQFIRWLSPKHHSIAERLKTERQVLAGAIRQKELELVELTRFRYIARPKPAGVPHHAKAGNLNYAIFSGET
SGEFILTLDADHIPKPQFLKRVLPYFYTYNLFNGKYEQNRIAFVQTPQDFYNIPPSDPFGHRASLFYGPLQQGKDGMNAA
FYTGTNAILRREALINVGLQYFADDFTKDEKRLDEFQLVGGLSSNSITEDMNTAMRLHGAGWKSVYHHELLAEGLAPDDL
SSTLKQRLRWAQGTIQVLVKENPLRKSGLTFWQRLQYFKTMYSYFSGFATLIFISCPIIYFFTEIVPVKTYGTDFILHFL
PTFIINRLTFVVAIWGIPASEIWRSEQYAIALFPIFIQAVWSVFTGQKMNFQVTPKERQSGIYLSMIWPQLLIFFLTIIG
IFWSLYSFAIGRLNHPWVNLLNSSWAVYNLLLLSGIIRASVWQMPKYDSKKV

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose. The thick cellulosic mats generated by this enzyme probably provide a specialized protective environment to the bacterium [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=422, Percent_Identity=27.9620853080569, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR005150
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF03552 Cellulose_synt; PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 79317; Mature: 79185

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVIGCLVLPSDVTGLGSPVSDKNFITSVKMTSINHDPTFSGNSRSTLKKRTLLFRYLAE
CCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
INLIFGLWYLQWRITNSINFDALWLSIPLLLAEIYSYLGGVMFVIGLWRPLVRQIKSLDQ
HHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPSLPQTDWPIVDVFITCYNEPPEMVEQTAQAALAIDYPPTKLYVYVLDDGNSPAMRAM
HCCCCCCCCCCCEEHEEEECCCCHHHHHHHHHHEEEEECCCCEEEEEEEECCCCHHHHHH
TEKLCIADLQSPLLQQEANRIDAERSHLVERLQKLESFTSNIQVAEEWLSKSSSVPNQDK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TTDEVLAQSLQQFIRWLSPKHHSIAERLKTERQVLAGAIRQKELELVELTRFRYIARPKP
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGVPHHAKAGNLNYAIFSGETSGEFILTLDADHIPKPQFLKRVLPYFYTYNLFNGKYEQN
CCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
RIAFVQTPQDFYNIPPSDPFGHRASLFYGPLQQGKDGMNAAFYTGTNAILRREALINVGL
CEEEEECCHHHCCCCCCCCCCCCCHHEECCHHCCCCCCCEEEEECCHHHHHHHHHHHHHH
QYFADDFTKDEKRLDEFQLVGGLSSNSITEDMNTAMRLHGAGWKSVYHHELLAEGLAPDD
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCH
LSSTLKQRLRWAQGTIQVLVKENPLRKSGLTFWQRLQYFKTMYSYFSGFATLIFISCPII
HHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFFTEIVPVKTYGTDFILHFLPTFIINRLTFVVAIWGIPASEIWRSEQYAIALFPIFIQA
HHHHHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHH
VWSVFTGQKMNFQVTPKERQSGIYLSMIWPQLLIFFLTIIGIFWSLYSFAIGRLNHPWVN
HHHHHCCCCCEEEECCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLNSSWAVYNLLLLSGIIRASVWQMPKYDSKKV
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AVIGCLVLPSDVTGLGSPVSDKNFITSVKMTSINHDPTFSGNSRSTLKKRTLLFRYLAE
CEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
INLIFGLWYLQWRITNSINFDALWLSIPLLLAEIYSYLGGVMFVIGLWRPLVRQIKSLDQ
HHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPSLPQTDWPIVDVFITCYNEPPEMVEQTAQAALAIDYPPTKLYVYVLDDGNSPAMRAM
HCCCCCCCCCCCEEHEEEECCCCHHHHHHHHHHEEEEECCCCEEEEEEEECCCCHHHHHH
TEKLCIADLQSPLLQQEANRIDAERSHLVERLQKLESFTSNIQVAEEWLSKSSSVPNQDK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TTDEVLAQSLQQFIRWLSPKHHSIAERLKTERQVLAGAIRQKELELVELTRFRYIARPKP
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGVPHHAKAGNLNYAIFSGETSGEFILTLDADHIPKPQFLKRVLPYFYTYNLFNGKYEQN
CCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
RIAFVQTPQDFYNIPPSDPFGHRASLFYGPLQQGKDGMNAAFYTGTNAILRREALINVGL
CEEEEECCHHHCCCCCCCCCCCCCHHEECCHHCCCCCCCEEEEECCHHHHHHHHHHHHHH
QYFADDFTKDEKRLDEFQLVGGLSSNSITEDMNTAMRLHGAGWKSVYHHELLAEGLAPDD
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCH
LSSTLKQRLRWAQGTIQVLVKENPLRKSGLTFWQRLQYFKTMYSYFSGFATLIFISCPII
HHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFFTEIVPVKTYGTDFILHFLPTFIINRLTFVVAIWGIPASEIWRSEQYAIALFPIFIQA
HHHHHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHH
VWSVFTGQKMNFQVTPKERQSGIYLSMIWPQLLIFFLTIIGIFWSLYSFAIGRLNHPWVN
HHHHHCCCCCEEEECCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLNSSWAVYNLLLLSGIIRASVWQMPKYDSKKV
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382968 [H]